Pluralibacter gergoviae: LG71_24985
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Entry
LG71_24985 CDS
T03300
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pge
Pluralibacter gergoviae
Pathway
pge00260
Glycine, serine and threonine metabolism
pge00261
Monobactam biosynthesis
pge00270
Cysteine and methionine metabolism
pge00300
Lysine biosynthesis
pge01100
Metabolic pathways
pge01110
Biosynthesis of secondary metabolites
pge01120
Microbial metabolism in diverse environments
pge01230
Biosynthesis of amino acids
Module
pge_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pge_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pge_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
pge00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LG71_24985 (thrA)
00270 Cysteine and methionine metabolism
LG71_24985 (thrA)
00300 Lysine biosynthesis
LG71_24985 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LG71_24985 (thrA)
Enzymes [BR:
pge01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LG71_24985 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LG71_24985 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
AIR02954
UniProt:
A0AAU8RF95
LinkDB
All DBs
Position
complement(5352806..5355268)
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNASQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNITDAERIFAELLQGLADAQPGFPLERLAATVEQEFAQIKHVLHGISLLGQCPDGVNA
ALICRGEKLSIAIMAGLLEARDHKVSVIDPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKTMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASSD
EDALPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCVRAKRAMEDEFYLELKEGLLEPLSIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVVHQMLFNTDQVIEVFVIGVGGVGAAL
LEQLKRQRSWLKNKHIDLRVCGVANSRALLTSVHGLDLENWQGALAEAKEPFDIERLTRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHELRQAAAGSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRTA
REMGFTEPDPRDDLSGMDVARKLLILARETGRQLELADIQVESVLPAHFDDGGDTDDFMA
RLPQLDDEFSARIARARDAGKVLRYVGNIEEDGVCRVKIAEVDDSDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtcttgaagttcggcggtacatcagtggcgaatgcggaacgttttctgcgtgtc
gccgatattctggaaagtaacgccagtcaggggcaggtagcgaccgtgctctctgccccg
gccaaaatcaccaaccacctcgtggcgatgattgaaaaaaccattggtggtcaggatgct
ctgccgaatatcaccgacgccgaacgtatttttgccgaactgctgcaggggctcgccgac
gcccagcccggttttcctctcgaaagactcgccgctaccgttgagcaggagtttgctcag
atcaaacatgtcctgcacggcatcagcctgctggggcagtgcccggacggcgtcaatgcg
gcgctgatctgccggggcgaaaagctctcaatcgccatcatggcgggcctgctggaggcg
cgcgaccacaaggtcagcgtcatcgatccggtggagaagctgcttgccgtcggccactat
cttgaatctaccgtcgatatcgccgaatccacccgccgcattgccgccagccagatcccg
gcggaccacatgatcctgatggccggctttaccgccggcaacgataagggcgagctggtg
gtgttggggcgcaacggctccgactactccgccgcggtgctggccgcctgcctgcgcgcc
gactgctgcgaaatctggaccgatgtcgacggcgtctatacctgcgatccgcgccaggtc
ccggacgcgcgtttgctgaaaacgatgtcctatcaggaggcgatggagctctcctacttc
ggcgctaaggtgctgcatccgcgcactatcgccccgattgcccagttccagatcccctgc
ctgattaaaaataccggcaacccgcaggcgccgggtacgctgatcggcgccagcagcgat
gaagacgcgctgccggtgaagggcatttctaacctcaacaacatggcgatgttcaacgtc
tccggaccgggcatgaagggcatggtcggtatggcggcgcgggtattcgccaccatgtcg
cgcgccgggatttcggtggtgctgatcacccagtcctcgtcggagtacagcatcagcttc
tgcgtgccgcagagcgactgcgtccgggcgaagcgggcgatggaagatgagttctacctg
gagctgaaagagggtctgctggagccgctctccatcatggagcggctggccattatctcg
gtggtcggcgacggtatgcgcactctgcgcggcatctccgccaagttctttgccgccctg
gcccgcgccaatatcaatatcgtcgccattgcccagggctcttccgagcgctctatctcg
gtggtggtgaataacgacgatgccaccaccggcgtgcgcgtggtgcaccagatgctgttt
aacaccgatcaggtgatcgaagtgtttgtgatcggcgtcggcggcgtcggcgcggcgctg
ctggagcagctcaagcgccagcgcagctggcttaagaacaagcatatcgacttgcgggtt
tgcggcgtagccaactcccgcgcgctgctcaccagcgttcacggcctcgatctcgaaaac
tggcagggcgcgctggcggaggccaaagagccgttcgacattgagcgcctgacccgactg
gtgaaagagtatcacctgctcaacccggtcattgttgactgcacatctagccaggccgtg
gcggaccagtacgccgacttcctgcgcgaaggtttccacgtggtgacgccaaacaaaaag
gccaacacctcgtcgatggactattaccacgagctgcgtcaggccgcggcgggctcacgc
cgcaagttcctctatgacactaacgtcggcgccgggctgccggtgattgagaacctgcag
aatctgcttaacgccggtgacgaactgcagcgcttctccggcattctttccggttcgctg
tcgtttattttcggcaagttggatgaggggatgagcctgtcggaagccacccgcacggcg
cgggaaatgggctttaccgaaccggatccgcgcgacgacctttccggcatggacgtggcg
cgcaagctgctgatcctcgcccgcgaaacgggccgccagcttgagcttgccgatattcag
gtggagtcggtgctgccggcccactttgacgacggcggtgatactgacgactttatggcg
cgtctaccgcagctggacgatgagttctcggcgcgcatcgcccgcgcccgcgacgcgggc
aaagtgctgcgctacgtcggcaatatcgaagaagacggcgtctgccgggtgaaaattgcc
gaagtggacgacagcgatccgctgtataaagtgaagaacggcgagaacgcgctggccttc
tacagccactattatcagccgctgccgctggtgctgcgcggctatggcgccggtaacgac
gtgacggcggccggggtgtttgccgatctgctgcgcaccctgtcatggaagttaggagtt
taa
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