Pseudochaenichthys georgianus (South Georgia icefish): 117450938
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Entry
117450938 CDS
T09629
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pgeo
Pseudochaenichthys georgianus (South Georgia icefish)
Pathway
pgeo04217
Necroptosis
pgeo04620
Toll-like receptor signaling pathway
pgeo04621
NOD-like receptor signaling pathway
pgeo05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
pgeo00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
117450938 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117450938 (tyk2)
04621 NOD-like receptor signaling pathway
117450938 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
117450938 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pgeo01001
]
117450938 (tyk2)
Enzymes [BR:
pgeo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117450938 (tyk2)
Protein kinases [BR:
pgeo01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117450938 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
SH2
ABC1
Kinase-like
Kdo
RIO1
FERM_C_FAK1
ANTAR
Motif
Other DBs
NCBI-GeneID:
117450938
NCBI-ProteinID:
XP_033944863
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All DBs
Position
8:complement(18831990..18842261)
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AA seq
1182 aa
AA seq
DB search
MKPDCPFFSPLALNDLAVPTMSKRGSSKHSRHGAFPSLCDPPQGPGIHVYMFWSKEGERY
LSHTDGEVTAEDLCISAAEAVGITPLCHVLFALYNPQSSCWYSPNHTFTPENSSLVLHYC
MRFYFRNWHRLSGKEPSVYRYALRSGAGQGGSPLLEIASLQYLFSQAKYEFVNEVVQVED
VDSEEKLNRFENESLGMAVLQLSHQAMETGCSLQDVAQKISFLRCIPRSFAKHISRVNFL
TKIRIRRVFAEFVRTFQQHTVDKGRLGAQEIMYKYISTLEHLSPSFGTETFSVSQLELRE
DGDGSSSFSNTTQTEGASKGNCIDPATHEIMMSGTKGIQWRKVSGQKALANTYLRNDYMK
KRKQSDQPNANTPNKWTSFCDFPEITHIALTGDNVCISTQDNHCMEVQMNSSQEARSFIS
LLDGYNRLTAFAHHFLCHEVAPPRVVLSVANGLHGPLHDDFVLLKLKKEAEEGAFLVRWS
AHDYHCIILAVMKKSENGSRPNHKQFRILLKGSKFCLEGWDREFSSMKELTESLKTFVLQ
SGSDSFTVKKCCFPKQAELSNLLVMRQGARTESLFLNTTQLRFHQIKERELVQEQHLGRG
TRTNIYSGRLLVRGGGGNDEDDEFNNNLADRKGIPVVLKILDQSDKDIDIGFLETASLMS
QVSHSHLVFVHGVSVKGSENIMVEEFVEFGPLDVFLRKEKASVTPQWKFIVAKQLAIALN
YLETKRLFHGNVCAKNILVARRGLELGTSPFVKLSDPGIALSVLSREERLERIPWIAPEC
VESGAPIGNVADQWSFGVTLLEICNNGDLPMSGSTLSEKERFYQQKGRLAEPSSQELARF
ISMCMTYEPMERPSFLTVLRELTDIIIKNPDISPSETLPDSDPSVFHKRYLKKMRDLGEG
HFGKVTLYQYDPANDGTGERVAVKALKQENSQVLEGWMKEIDILKSLYHSNIVKYKGCCT
ELGGQVVQLIMEYLPLGSLKEYLPKRKLGRPQALMFAQQICQGMEYLHSKRYIHRDLAAR
NVLVENESLVKIGDFGLTKYIPEGDIYYRVREDGDSPVFWYALECLKENKFSFASDVWSF
GVTLYEILTRCVHRQSPQEKFREMMQDTQEQMTVMVLIKLLEKQHRLPGPENCPHEVKIL
MEQCWAADSAQRPSFETLIEKFEAIRQTYWLSNIKFSSAQIS
NT seq
3549 nt
NT seq
+upstream
nt +downstream
nt
atgaagcccgactgtcccttcttctctcctttggctttgaatgatttggctgtccccacc
atgtccaaacgtgggtcatccaagcattcaaggcacggggcgttcccgagcctgtgtgac
ccccctcagggtcctggtatccatgtttacatgttctggtcaaaggaaggggaaagatat
ttgtcccatacagatggagaagtcacagcagaagacctgtgcatctcagctgcggaggct
gtaggtataacacctctatgccatgtgttgtttgcgctgtacaatccacaatcaagctgc
tggtacagtccaaaccacacgtttactccagagaactccagccttgtacttcactactgt
atgaggttctactttcggaactggcacagactcagtgggaaggagccgagtgtttaccgt
tatgctctcagatctggggcaggtcagggaggttctcccttgcttgaaatcgcatcctta
caatacctgttctcccaggcaaaatatgaatttgtgaacgaagtggtacaggtggaagac
gtggactcagaggagaagttaaatcgcttcgaaaatgagagcttggggatggctgtgctt
caactctcacatcaggcaatggaaacaggctgctccttgcaagatgttgcccaaaaaatc
agcttcttacgatgcattccaagatctttcgccaaacacatttccagagtcaacttcctg
acaaagatcaggatccgtcgggtgtttgcagagtttgtgcggaccttccagcagcacact
gttgataaggggagactgggcgcacaggaaatcatgtacaagtacatctctactcttgaa
cacttgtcaccgagttttggaacagaaaccttctctgtatcccagctggagcttcgagag
gacggggatggaagcagctctttctccaacaccacccaaacagagggtgcctcaaaaggc
aactgtatagatcctgccacacacgagataatgatgtcaggcaccaaggggattcagtgg
aggaaagtgtctggtcagaaggcactggcaaacacttacctccgaaatgactacatgaag
aaaagaaaacagtccgaccaaccgaacgcaaacactcccaacaaatggacgtccttctgt
gatttccctgaaattacgcacatagccctcactggagataatgtgtgcattagcactcag
gacaaccactgcatggaggttcagatgaactccagccaggaggcccgttccttcatctcc
ctgcttgatggatacaaccggctgactgcattcgcccaccactttctttgtcatgaagtg
gctcccccaagggtagtgctgagtgtagcaaatggactgcatggacctctgcatgatgat
tttgtgctgctgaagctgaaaaaggaggcagaggagggagctttcctggtacgctggagt
gcccacgactatcactgcatcatcctagcagtcatgaaaaaaagtgagaatggatcaagg
ccaaaccacaagcagtttcggattctgctcaagggttccaaattctgtctggagggctgg
gatcgagagttctccagtatgaaggagctcacggaaagcctcaagacctttgtcctccag
tctggttcggacagctttactgtaaagaaatgctgttttccaaaacaagcagagctctcc
aaccttctggtgatgaggcaaggtgctcgcacggagtccttgttcctgaacacaactcag
ctgcgcttccaccagatcaaggaaagagagcttgtacaggaacaacatttgggccgcggg
acaagaactaacatctactcaggacgtctgctggtgcgaggcggggggggaaatgatgag
gatgatgagttcaacaacaacttggctgaccgcaaaggaatccctgtggttctcaagatt
ctggaccaaagtgataaagatatcgatataggttttttagaaactgcgagtctcatgagc
caggtgtcccacagtcacctggtgtttgtacatggcgtgtcagtcaaaggatctgaaaat
atcatggtggaagaatttgtggagtttgggcctttggatgttttccttcgaaaggaaaag
gcctctgtgactcctcagtggaaattcattgttgcaaaacagcttgccattgccctcaat
tatcttgagaccaaacggctgtttcatggaaacgtctgtgctaagaacattctggtggca
aggcgaggtctcgagctcggcacctctccttttgtcaagctgagcgacccaggaattgcc
ctgagtgtcctttcaagggaagagcgtcttgagcgtatcccctggattgcccccgagtgt
gtggaaagcggcgcacccattggaaatgttgctgaccagtggagctttggcgttaccttg
ctggaaatctgcaacaacggcgatcttccaatgagtggcagcacattgtccgagaaagag
cgcttttatcaacaaaaaggccgtttagcagaaccatcctcccaggaactggctcgcttc
atcagcatgtgtatgacctacgagccaatggagaggccttcgttcctcactgtgctcaga
gagctcacagacatcataatcaaaaatccggatatatcccccagtgaaactctccctgac
tcagacccgagcgtgttccacaaacgctacctgaaaaagatgagggacttgggagaggga
cactttgggaaggtgactctctaccagtacgacccggccaatgatgggacaggagagcgc
gtggccgtgaaggctctgaaacaagagaacagtcaagtgcttgaaggctggatgaaggag
attgacatcctcaagtcactctatcacagtaacattgtcaagtacaaaggctgttgtact
gaactcggaggacaggtggtgcagttgataatggagtaccttcctctggggagcctgaag
gagtaccttcccaaacgtaagctgggaaggcctcaggcccttatgttcgctcagcagatc
tgtcagggtatggagtacttgcactccaaacgatacatccatcgagacctcgctgcccga
aatgtcttagtggaaaatgagagtttggtgaagattggagactttggcctgaccaaatac
atacctgaaggcgatatctactatcgtgtccgtgaggatggggacagtcccgtcttctgg
tatgcccttgagtgcttgaaggaaaataaattctcctttgcctcagatgtttggtccttt
ggcgttacattgtatgagatcctgacccgctgtgtacatcgccaaagcccgcaagagaag
ttcagggaaatgatgcaagacacccaggaacagatgactgtgatggtgctcataaagctg
ttggagaagcagcaccgattgcctggccccgaaaactgtccacatgaggtgaagatttta
atggagcagtgttgggctgcagactcagcacaacggccatcattcgaaaccctcatcgaa
aagtttgaggccattcgccaaacatactggctctccaatatcaagttttcctcggctcag
attagctga
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