Pteropus vampyrus (Indian flying fox): 120581644
Help
Entry
120581644 CDS
T07511
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
120581644 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pgig03032
]
120581644 (TOP2B)
03036 Chromosome and associated proteins [BR:
pgig03036
]
120581644 (TOP2B)
Enzymes [BR:
pgig01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
120581644 (TOP2B)
DNA replication proteins [BR:
pgig03032
]
Eukaryotic type
DNA Topoisomerases
120581644 (TOP2B)
Chromosome and associated proteins [BR:
pgig03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
120581644 (TOP2B)
Centrosome formation proteins
Centriole proteins
120581644 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
120581644
NCBI-ProteinID:
XP_039692668
LinkDB
All DBs
Position
Unknown
AA seq
1620 aa
AA seq
DB search
MAKAGGGGAGAGGNGALTWVTLFDQNNAAKKEESETANRNDSSKKLSVERVYQKKTQLEH
ILLRPDTYIGSVEPLTQLMWVYDEDVGMNCRDITFVPGLYKIFDEILVNAADNKQRDKNM
TCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDEEKKVTGGR
NGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSESKIKHFDGEDYTCITFQPD
LSKFKMEKLDKDIVALMTRRVYDLAGSCKGVKVIFNGKKLPVNGFRSYVDLYVKDKLDET
GVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVK
KKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKNFGSKCQLSEKFFKAA
SNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEG
DSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSY
DDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASK
NKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAG
PEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKE
LILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQ
ALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARRLFPPVD
DNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDG
LDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEP
MLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVL
FDHMGCLKKYETVQDILKEFFDLRLSYYGLRREWLVGMLGAESAKLNNQARFILEKIQGK
ITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKATEEEETQNQHDDSSSDSGTPSGPDF
NYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFAEELDKVEAQE
REDILAGMAGRTIKGKVGKPKVKKLQLDETMPSPYGRRIVPEITAMKADASKKLLKKKKG
DLDTTTVKVEFDEEFSGTPVEGTGEEALIQSVPVNKGPKPKREKKEPGTRVRKTPTSSGK
SSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAD
DDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKTTPEKSSHDKKSQDF
GNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTT
PKPKRTPKQKKVETINSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS
KTPSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcgcgggagccggcggcaacggggcactgacctgggtg
actctttttgatcagaacaatgctgcaaaaaaagaagagtctgaaactgcaaatagaaat
gattcttcaaagaagttgtctgttgagagagtatatcagaaaaagacacaactcgaacac
attctccttcgtcctgatacatacattgggtcagtggagccattgacacagttaatgtgg
gtgtatgatgaagatgtgggaatgaattgcagggatattacctttgtgccaggtttatac
aagatctttgatgaaatcttggttaatgcagctgacaataaacagagggataagaacatg
acctgtattaaagtttctattgatcctgaatctaacattataagcatttggaataatggg
aaaggcattccagtggtagaacacaaagtagagaaagtttatgttccagcgttaattttt
ggacagcttttaacatccagtaactatgatgatgaggagaaaaaagtaacaggtggtcgc
aatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaactgct
tgcaaagaatacaaacatagttttaagcagacctggatgaataatatgatgaagacttct
gaatccaaaattaaacatttcgatggtgaagattacacttgcataacattccaaccagat
ctgtccaaatttaagatggaaaaacttgacaaggatattgtggctctcatgaccagaaga
gtttatgatctcgctggttcatgcaaaggggtcaaggtcatatttaatggaaagaaattg
cctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaaattggatgaaact
ggagtggctctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtcttaca
ttgagtgaaaaaggattccagcaaatcagctttgtaaatagtatcgcaacaacaaaaggt
ggacggcacgtggattatgtagtagatcaagttgttggtaaactgattgaagtagtgaag
aaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatatatgggtt
tttattaattgccttatcgaaaatccaacttttgattctcagactaaagaaaacatgact
ttgcagcccaaaaattttgggtccaaatgtcaactgtcagaaaaatttttcaaagcagcc
tctaactgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagactcag
ctgaacaagaagtgttcatcagtaaagtacagtaaaattaaaggtattcccaaactggat
gatgctaatgatgctggtggcaaacattccctagagtgtacactgatactaacagaggga
gactcagccaaatcactggctgtgtctggattaggtgtgatcgggagagacagatatgga
gtctttccactcaggggaaaaattcttaatgtacgagaagcttctcataaacagatcatg
gaaaatgcagaaataaacaatattattaaaatagttggtctacaatacaaaaaaagttat
gatgatgcagaatctctgaagactttacgctatggaaagattatgattatgactgatcag
gatcaagatggttctcatataaaaggccttcttattaatttcatccatcacaattggcca
tcacttttgaagcatggttttcttgaagagttcattactccaattgtaaaggcaagcaaa
aataagcaggaactttccttctacagtattcccgaatttgatgagtggaaaaaacatata
gaaaaccagaaagcctggaaaataaaatactacaaaggattgggtaccagtacagctaaa
gaagcaaaggaatattttgctgatatggaaaggcaccgcatcttgtttagatatgctggt
cctgaagatgatgctgccattaccttggcattcagtaaaaagaagatcgatgacagaaaa
gaatggttaacaaattttatggaagaccggagacagcgtaggttacatggcttaccagag
caatttttatatggtacagcgacaaagcatttgacgtacaatgatttcatcaacaaggaa
ttgattctcttctcaaattcagacaatgaaagatctataccatctcttgttgatggcttt
aaaccaggccaacgaaaagttttatttacctgtttcaagagaaacgataaacgtgaagta
aaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaacaa
gcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaacattaac
ttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagc
ccgcgttatattttcacaatgttaagctctttagcaaggcggctttttcctcctgtggat
gataacctgcttaaattcctgtatgatgataatcaacgtgtagagcctgagtggtatatt
cccataatccccatggttttaataaatggtgctgagggcattggtactggatgggcttgt
aaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggc
ttggatcctcatcccatgcttccaaactacaaaaactttaaaggaacgatccaagaactt
ggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacacagtagag
attacagagcttccagttagaacttggacacaggtatacaaagaacaagttttagaacct
atgctaaatggaacagataaaacaccagcattaatttctgattataaagaatatcatact
gacacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagct
gctggactgcacaaagtttttaagcttcaaactactcttacttgtaattccatggtactc
tttgatcatatgggctgtctgaagaagtatgaaactgtacaggacattttgaaagagttc
tttgatttacgactaagttattatggtttacgtagggagtggcttgtagggatgttggga
gcagaatctgcaaagcttaacaatcaagctcgtttcattttagagaagatacaaggaaaa
attactatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttat
gaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcaacagaagaggaagaa
acacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccctgatttt
aattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaattgatt
aaacagagagatgcgaaaggacgagaggtcaatgatcttaaaagaaaatctccttcagat
ctttggaaagaagatttagcagcatttgctgaagaactggataaagtggaagctcaagaa
cgagaagatattctggctggaatggctggaagaacaataaaaggtaaagttggcaaacct
aaggtgaagaaacttcagttggatgagactatgccctcaccttacgggaggagaatcgtt
cccgaaatcactgctatgaaggcagatgccagcaaaaagttgttgaagaagaaaaagggc
gatcttgataccacaacagtaaaagtggaatttgatgaagaattcagtggaacaccagta
gaaggtacaggcgaagaggcattgatacagtcagtgcctgtaaataaaggtcccaaaccc
aaaagggagaagaaggagcctggtaccagggtgagaaaaacacctacatcatctggtaaa
tctagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaa
agcgacttggaagaaacagaacctgtggttattccaagagattctttgcttaggagagcg
gctgctgaaaggcctaagtacacgtttgatttctcagaagaagaggatgatgatgctgat
gatgatgatgacaataatgatttagaggaattaaaagttaaagcatctcccataacaaat
gatggggaagatgagtttgttccttcagatggcctagataaagatgaatatacattttca
ccaggcaaatctaaaactactccagaaaaatcttcgcatgataaaaaaagtcaggatttt
gggaatcttttctcatttccttcatactctcagaagtcagaagatgattcagctaaattt
gacagtaatgaagaagattctgcttctgttttttcaccgtcatttggtctgaaacaaaca
gataaagtaccaagtaaaacagtagctgctaaaaaaggaaaaccatcttcagatacaacc
cctaagcccaagagaactcccaaacagaagaaagtagagactataaactctgactcagat
tcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggccgaggggcaaag
aaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatcc
aaaacaccaagcaagaaaccgaagaaaacatcttttgatcaggattcggatgtggacatc
ttcccatcagacttcacttctgaaccaccttctctgccacggacgggtcgggctaggaaa
gaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgtttaat
taa
DBGET
integrated database retrieval system
