Pteropus vampyrus (Indian flying fox): 120583126 Help Entry 120583126         CDS       T07511                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism pgig  Pteropus vampyrus (Indian flying fox) Pathway pgig01521   EGFR tyrosine kinase inhibitor resistance pgig04151   PI3K-Akt signaling pathway pgig04217   Necroptosis pgig04380   Osteoclast differentiation pgig04550   Signaling pathways regulating pluripotency of stem cells pgig04620   Toll-like receptor signaling pathway pgig04621   NOD-like receptor signaling pathway pgig04630   JAK-STAT signaling pathway pgig04658   Th1 and Th2 cell differentiation pgig04659   Th17 cell differentiation pgig05140   Leishmaniasis pgig05145   Toxoplasmosis pgig05152   Tuberculosis pgig05160   Hepatitis C pgig05161   Hepatitis B pgig05162   Measles pgig05163   Human cytomegalovirus infection pgig05164   Influenza A pgig05165   Human papillomavirus infection pgig05166   Human T-cell leukemia virus 1 infection pgig05167   Kaposi sarcoma-associated herpesvirus infection pgig05168   Herpes simplex virus 1 infection pgig05169   Epstein-Barr virus infection pgig05171   Coronavirus disease - COVID-19 pgig05200   Pathways in cancer pgig05203   Viral carcinogenesis pgig05212   Pancreatic cancer pgig05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:pgig00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     120583126 (JAK1)    04151 PI3K-Akt signaling pathway     120583126 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     120583126 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     120583126 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     120583126 (JAK1)    04621 NOD-like receptor signaling pathway     120583126 (JAK1)    04658 Th1 and Th2 cell differentiation     120583126 (JAK1)    04659 Th17 cell differentiation     120583126 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     120583126 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120583126 (JAK1)    05203 Viral carcinogenesis     120583126 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     120583126 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     120583126 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     120583126 (JAK1)    05161 Hepatitis B     120583126 (JAK1)    05160 Hepatitis C     120583126 (JAK1)    05171 Coronavirus disease - COVID-19     120583126 (JAK1)    05164 Influenza A     120583126 (JAK1)    05162 Measles     120583126 (JAK1)    05168 Herpes simplex virus 1 infection     120583126 (JAK1)    05163 Human cytomegalovirus infection     120583126 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     120583126 (JAK1)    05169 Epstein-Barr virus infection     120583126 (JAK1)    05165 Human papillomavirus infection     120583126 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     120583126 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     120583126 (JAK1)    05140 Leishmaniasis     120583126 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     120583126 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pgig01001]     120583126 (JAK1) Enzymes [BR:pgig01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      120583126 (JAK1) Protein kinases [BR:pgig01001]  Non-receptor tyrosine kinases   JAK family [OT]    120583126 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 SH2_1 ABC1 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  120583126 NCBI-ProteinID:  XP_039694391 LinkDB All DBs Position Unknown AA seq 1159 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELN WFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKQKKDEEKNKIR EEWSNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKAEVSQAIWPRVSLQPGPGAGADGTTLGGWGEVGSCLFESDSTQLSRHWLLGILGFC SPAQTPLLLSTEISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIY SGTLVDYKDDEGISEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCV RDVENIMVEEFVEGGPLDLFMHRKSDVLTTPWKLKVAKQLASALSYLEDKDLVHGNVCTK NLLLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWS FGTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFF RAIMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEG DNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEF LPSGSLKEYLPKNKNKINLNQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVK IGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYC DSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEIYQLMRKCWEFHPSN RTTFQNLIEGFEALLKLAA NT seq 3480 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgcgg agctccaagaagaccgaggtgaatctggaagcccctgagccaggggtggaagtgctcttc tatctgtcggatagggagcccctccggctgggcagtggagagtacactgcagaggagcta tgcatccgggcggcacaggaatgctgtatctctcctctgtgtcacaacctttttgccttg tatgatgagaacaccaagctctggtatgccccaaatcgcaccatcactgtcgacgataag acatcgcttcggctccactatcggatgaggttctattttaccaactggcatgggaccaat gataatgagcagtcagtatggcgacattctccgaagaagcagaaaaatggctatgagaaa aaaaaagttccagatgcaactcctctccttgacgccagctccctggagtatctgtttgct cagggacagtatgacttggtcaaatgcctggctccaatccgagaccccaagactgagcag gatgggcatgacatagagaacgagtgtctggggatggctgtcctggccatctcccattat gccatgataaagaagatgcagttgccagaactccccaaggacatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgaggata aataatgtcttcaaggatttcctaaaggaatttaacaacaagaccatttgtgacagcagt gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggtgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagctgaat tggtttcatccaaatgacagtggaaatgttctctactatgaagtgatggtgactggaaat cttggaatccagtggaggcagaaaccaaatgttgttcctgtcgaaaaggaaaaaaataaa ctgaaacggaaaaaactggaaaataaacagaagaaagatgaggagaaaaacaaaatccgg gaagagtggagcaatttttcttacttccctgaaatcactcatattgtaataaaggaatct gtggtcagcattaataagcaagacaacaaaaaaatggaactgaagctctcttcgcacgag gaggccttgtcttttgtgtccctggtagatggctactttcggctcacagcagacgcccat cattacctttgcaccgatgtggctcccccactgatcgtccacaacatacagaatggctgt catggtccaatctgcacagaatatgccatcaataaattgcggcaagaaggaagcgaggag gggatgtacgtgctgcggtggagctgcactgacttcgacaacatcctcatgaccgtcacc tgctttgaaaaggctgaggtcagtcaagccatatggcccagggtgtcattgcaacctggc ccaggagctggtgcagatgggactactcttggggggtggggggaagttgggagttgcctg tttgaatccgactctacccagctcagcagacactggctacttggaatcttgggcttttgc tcccctgctcagacacctctcctcttgtccacagaaatctccaatctgctggtggctact aagaaagcccaggagtggcagcctgtctaccccatgagccagctgagtttcgatcggatc ctcaagaaagacattatgcaaggcgaacaccttgggagaggcacgcggacacacatctac tctgggaccctggtggattacaaggatgacgaaggaatatctgaagagaagagaataaaa gtgatcctcaaagtcttagatcccagccacagagacatttctctggccttctttgaggca gccagcatgatgagacaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtc cgagacgtggagaatatcatggtggaagagtttgtggagggagggcccctggatctcttc atgcaccggaaaagtgatgtcctcaccacaccatggaagctcaaagttgctaaacagttg gccagtgccttgagttacttggaggataaagacctggtccacggaaacgtgtgcacgaaa aacctcctcctggctcgtgagggcatcgacagtgagtgtggcccattcatcaagctcagt gaccccggcatccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccgtgg attgctcctgagtgtgtcgaagactccaagaacctgagcgtggccgctgacaagtggagc tttggaaccacactctgggaaatctgctacaacggcgagatccccctgaaagacaagacg ctgatcgagaaagaaagattctatgaaagccggtgcaggccagtgacaccatcttgtaag gagctggctgaccttatgactcgctgcatgaactatgaccccaaccagagaccctttttc cgagccatcatgagagacatcaataagctggaagagcagaatccagacattgtttcagaa aaaaagccagcaactgaagtggaccccacacattttgaaaagcggttcttgaagaggatc cgtgatttgggagagggccactttgggaaagttgagctctgcaggtatgaccctgaaggg gacaatacaggagagcaggtggctgtcaaatccctgaagcctgagagcggaggtaaccac atagctgatctgaagaaggaaattgaaatcttaaggaacctctatcacgagaacattgtg aagtacaaaggcatctgcacagaagatggaggaaatggtattaagctcatcatggaattt ctgccttcaggaagcctgaaggaatatcttccaaagaataagaacaaaattaacctcaac cagcagttaaaatatgccgttcagatttgtaaggggatggactatttgggttcacgacaa tacgttcaccgagacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaa atcggagactttgggttaaccaaagcaatcgaaaccgataaggagtactacacagtcaag gatgatcgggacagccctgtgttttggtacgctccagaatgtttaattcagtgtaaattt tatatcgcctctgacgtctggtctttcggagtgactctgcacgagctgcttacttactgt gattcagattccagtcccatggcgttgttcctgaaaatgataggccccactcatggccag atgacagtaacaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacct aactgtccagatgagatttatcaacttatgagaaaatgctgggaattccacccatctaat cggacaacctttcagaaccttatcgaaggatttgaagcacttttaaaattagcagcatga

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