Pteropus vampyrus (Indian flying fox): 120583726
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Entry
120583726 CDS
T07511
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig00310
Lysine degradation
pgig01100
Metabolic pathways
pgig05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
120583726 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
120583726 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pgig03036
]
120583726 (DOT1L)
Enzymes [BR:
pgig01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
120583726 (DOT1L)
Chromosome and associated proteins [BR:
pgig03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
120583726 (DOT1L)
HMT complexes
Dot1-containing complex
120583726 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
120583726
NCBI-ProteinID:
XP_039695071
LinkDB
All DBs
Position
Unknown
AA seq
1715 aa
AA seq
DB search
MDYFGSFRFWKDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCD
KYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVY
GETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAE
TMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKER
FANMKEGTAVTGSHVSGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWT
GKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVPESKVAV
TADTPVDSGAEEEKTGTATIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTANPERKP
RKSPTALDLLHAQTVSQAAASPQDAYKSPHSPFHQLPPSVQRHPPDQLLLAPTPPALQKL
LESFRIQYLQFLAYTKTPQYKAGLQQLLDQEKEKNARLLGAAQQLFGHCQAQKEEIKRLF
QQKLDELGVKALTYDDLIQAQKEISAHNQQLREQTEQLETDNRALRGQSLQLLKARCEEL
RLDWPTLSLEKLLKEKQALKSQISEKQRRCLELQISIVELEKSQRQQELLQLKSCVPPDE
AVAMHLRGKGGLGRELEVEPSRLHLELDCSKFSLPPFSSLSPELSVNGHAAAYELCGTLS
RPPSKQNTPQDLASVLDQEVVPCTPSHGSRPRLDKLSGLASPDYTRLSPAKLVLRRHLSQ
DHAAGSKAATSELHPRAEHVKENGLPYHSPGLANGIKLSPQEPRPSSPVALQMTGEKGSE
KGLKERGHASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRSTPSPVPQA
RESSSTLEKQVGAHAHGAGSKGLTLAPTAGFSYAGSVAITGALTGSPAPLAPGAEPPAFD
ESSSSGSLFAPMGSRSSTPQHPPLLAQPRNSGPASPAHQLCASPRLGATQGPLPDASKGD
LPSEAGFSDPESEAKRRAVFTVSASAGSAKQSPSSKHSPLPAGTQNHGQDSRKRGRRKRA
SAGTPSLSTGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQPLEITAISSPESSLKS
SPIPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEPGSARIERKIATISLESK
SPPKTLENGGGLAARKPMPASEPVNSSKWKATFSPISDLGLAKAADSPLQAGPALSQNSL
FAFRPAPEEPGPADAKLATHPRKSFPGAVPGAGGLSPSSNPSNGFAFSGGLAADLSLHSF
SDGASLPHKAPEAAGLGAPLSFPAPRGKEGGTEPSPFVNKRQLDGLGGLKGEGGKGREAE
LGPPTCAPSDKASAHGKAGKGRDREPDFKNGHNLFISAAAVPPGGLLSGPGLASAASSAG
STAPSAQTHRPFLGTFAPGPQFSLGPMSLQANLGPSVLQSLFSSVPAAAGLVHVSSAATR
LTNSHAMGSFSSGVAGGAVGGVSNHAVPSASAHPFGASFGSGAACHSSTLSLTPLQAVAS
TPASSFQAPPSMEPRPPPPPPPPPPGQPPAGPPTLHAPPPPNAALPPAPALHPANSEPVL
LQNLAPLSANQAFLPVSSAASLPPANSALSIKLASLPHKVSRPSFTVHHQPLPGLALAQA
APVLPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5148 nt
NT seq
+upstream
nt +downstream
nt
atggactacttcggaagcttcagattttggaaggacaaacaccacgatgctgctcacgaa
atcatcgagaccatcagatgggtctgcgaggaaattccggacctcaagctcgccatggag
aactacgtcctcattgactacgacaccaaaagctttgaaagcatgcagaggctttgtgac
aagtacaaccgggccatcgacagcattcaccagctgtggaagggcaccacgcagcccatg
aagctgaacacgcggccgtccaacggactcctgcggcacatcctgcagcaggtgtacaac
cactcggtgacggaccccgagaagctcaacaactacgagcccttctccccggaggtgtac
ggggagacctcctttgacctggtcgcgcagatgatcgacgagatcaagatgaccgaggat
gacctgttcgtggacctgggcagtggagtgggccaggtcgtgctgcaggttgccgcggcc
accaactgcaaacatcactacggcgtcgagaaagctgatatcccagccaagtatgcggag
accatggaccgcgagttcaggaagtggatgaaatggtacggaaaaaagcatgcagaatac
acactggaaagaggcgacttcctctcggaggagtggagagagcggatcgccaacacgagt
gttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaaggagcga
tttgcaaacatgaaggaaggaacagcagtgaccggttctcatgtttcaggtggcagaatc
gtgtcctcgaagccctttgcacctctgaacttcagaataaacagtagaaacttgagtgac
atcggcaccatcatgcgcgttgtggagctctctcctctgaagggctcggtgtcatggacg
gggaagccggtgtcctactacctgcataccatcgaccgcactatacttgaaaactatttt
tctagtctgaaaaatccaaaactcagggaggaacaagaggcagctcggcgccggcagcaa
cgagaaaacaagagcaacacgaccacgcccacgaaagtgcctgagagcaaggtggccgtg
actgcggacacccccgtggattctggtgctgaggaagaaaaaacagggacggctaccatc
aagaagccgtctccctccaaggcacggaaaaagaagctgaacaagaaggggcggaagctg
gctggccggaagcgcgggcgccccaagaagatgagcactgcgaaccccgagcgtaagccc
aggaagagcccaactgcactggacctgctgcacgcccagaccgtgtcccaggccgcggcc
tcgccgcaggatgcgtacaagtcacctcacagcccatttcatcagctacctcccagcgtg
cagcggcaccctcccgaccagctgctgttggcacccaccccccctgcactgcagaagctg
ctagagtccttcaggattcagtatctgcagttcctggcatacacgaagaccccccagtac
aaggccggcctgcagcagctgctggaccaggagaaggagaagaatgcccgcttgctgggt
gccgcccagcagctgttcggccactgccaggcccagaaggaagagatcaagaggctgttc
cagcagaagctggacgagctgggagtgaaggctctgacctacgacgacctgatccaggct
cagaaggagatctccgcccacaatcagcagctgcgggagcagacggagcagctggagacg
gacaaccgggcgctgaggggccagagcctgcagctgctgaaggctcgctgtgaggagctg
aggctggactggcccacgctgtccctggagaagctgctgaaggagaagcaggccctgaag
agccagatctcagagaagcagaggcgctgcctggagctgcagatcagcatcgtggagctg
gagaagagccagcggcagcaggagctcctgcagctcaagtcctgcgtgccgcctgacgag
gccgtggccatgcacctgcgtgggaagggtggcctgggccgagagctggaggtggagccc
agtcggctgcacctggagctggactgctccaagttttcactacccccgttcagcagcctg
agccccgagctctccgtgaacggccatgcagccgcctacgagctgtgcggcacactgagc
cggccaccatccaagcagaacacgccccaggacctggcctccgtgctggaccaggaagtc
gtgccctgcacccccagccacggcagccggccccggctcgacaagctgtcgggcctggcc
tcacctgactacactcggctctcaccagccaagctcgtgctgaggcggcacctgagccag
gaccacgccgccggcagcaaggcggccaccagtgagctgcacccacgagctgagcacgtc
aaggagaacggccttccataccacagtccaggcctggctaacggcatcaagctgagccct
caggagccacggccctcgtcccccgtggccttgcagatgaccggagagaagggcagcgag
aagggtctgaaggaacgcggccacgccagcagcggggaggccatcaccagcctacccgtc
agcatcccgctcagcactgtgcagcccagcaagctgcccgtcagcatccctctggccagc
gtggtgctgcccagccgcgccgagaaggtgagaagcacccccagccctgtgccgcaggcc
cgggagtcctcgtccaccctggagaagcaagtgggcgctcatgcccacggcgcggggagc
aaaggcctcaccctggcccccacagcaggcttttcctacgccggctcagtggctatcact
ggggccctgacaggcagcccggctccgctcgctcctggggccgagccccctgcctttgac
gagtcctccagctcggggagcctcttcgcacccatgggctcccgcagctcgacaccgcaa
caccccccactgctggcccagccccggaactccggcccagcctcgcctgcccaccagctc
tgtgccagcccccggctcggcgccacccagggcccgctccccgacgccagcaaaggggac
ctgccctccgaggccggcttctcggatccagagagcgaggctaaaaggagggctgtcttc
accgtgtcggccagcgccggcagcgccaagcagtcaccttccagcaagcacagccctttg
cccgcaggcacccagaaccacgggcaggacagccgcaagcggggcaggaggaagcgggcg
tcagcgggcacgcccagcctgagtacgggcgtgtcccccaagcgccgggccctgccgtcc
gttgccggcctcttcacgcagtcttcagggtcccccctcaacctcaactccatggtcaac
aacattaaccagcccttggaaatcacggccatctcgtcccccgagagctccctgaagagc
tcccccatcccttaccaggacaatgaccagccgcccgtgctcaagaaggagaagcccctg
agccagaccaacggggcccactactcccctctgacttcagacgaagagccaggctctgag
gatgagccgggcagcgccagaattgagagaaaaattgcaactatctccttagaaagcaaa
tctcctccaaaaaccttggaaaatggcggtggcctggcggcaaggaagcccatgcctgcc
agcgagccggtcaacagcagcaagtggaaggccaccttctcgcccatctccgaccttggc
ctggccaaggccgccgacagcccgctgcaggctggccccgccctgagccagaactccctg
ttcgctttccggcccgccccagaggagcccggcccggccgacgccaagctggccacccac
cccaggaagagcttccccggggccgtgccgggggccggtgggctgagccccagcagcaac
ccctccaacggcttcgccttcagcggaggcctggccgctgacctcagtttacacagtttc
agtgatggtgcttctctcccccacaaggcccccgaggcggccggcctgggcgcccccttg
agcttccctgccccacgaggcaaggagggtggcacggaacccagcccctttgtgaacaag
aggcagctggacggactgggcggcctgaagggcgagggcggcaagggcagggaggcagag
ctgggcccccccacgtgtgcgccctcggacaaggcctcggcacacggcaaggcgggcaag
ggccgggaccgcgagcccgacttcaagaacggccacaacctcttcatttccgccgctgcc
gtgccccccgggggcctcctcagcggcccgggcctcgcctcggcggcgtcctcggcgggc
agcacggcgccctccgcccagacgcaccggcccttcctgggcaccttcgcgcccggcccg
cagttttccctgggccccatgtccctgcaagccaacctgggcccatccgtgctgcagtcc
ttgttcagctccgtgcccgccgccgccggcctggtgcacgtctcgtccgccgcgaccaga
ctgaccaactcgcacgccatgggcagcttttcctccggggtggcaggcggcgcagttgga
ggtgtctctaaccacgcggtgccctccgcctccgctcatccgtttggagccagtttcggc
agcggggctgcgtgtcacagcagcacgctgagcttaaccccgctgcaggcggtggccagc
acccccgcctcttcctttcaggccccgccctccatggagccgaggccgcccccgcccccg
cctcctccacccccgggccagccccctgcggggccacccaccctccacgcacccccacct
cctaacgccgccttgcctcctgctcccgcgctacaccccgctaactctgagcctgtgctc
ctgcagaacctcgcgcctctctcggctaaccaagctttcttacctgtctcctctgccgcc
tctctgccgcctgctaacagcgctctgtccatcaagctcgcctccctcccgcacaaggtc
tcccgcccctccttcacggtgcaccaccagcccctgcccgggctggccctggcccaggcc
gcgcccgtgctcccgcaggccagctccacggggccgtccgccgtgtgggtttcccttggc
atgccgcctccttatgccgcgcgccttgcgggggttaagccgcgataa
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