Pteropus vampyrus (Indian flying fox): 120584753
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Entry
120584753 CDS
T07511
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig01521
EGFR tyrosine kinase inhibitor resistance
pgig01522
Endocrine resistance
pgig04012
ErbB signaling pathway
pgig04066
HIF-1 signaling pathway
pgig04140
Autophagy - animal
pgig04150
mTOR signaling pathway
pgig04151
PI3K-Akt signaling pathway
pgig04152
AMPK signaling pathway
pgig04211
Longevity regulating pathway
pgig04213
Longevity regulating pathway - multiple species
pgig04350
TGF-beta signaling pathway
pgig04371
Apelin signaling pathway
pgig04666
Fc gamma R-mediated phagocytosis
pgig04714
Thermogenesis
pgig04910
Insulin signaling pathway
pgig04931
Insulin resistance
pgig05163
Human cytomegalovirus infection
pgig05165
Human papillomavirus infection
pgig05170
Human immunodeficiency virus 1 infection
pgig05200
Pathways in cancer
pgig05205
Proteoglycans in cancer
pgig05207
Chemical carcinogenesis - receptor activation
pgig05210
Colorectal cancer
pgig05212
Pancreatic cancer
pgig05221
Acute myeloid leukemia
pgig05224
Breast cancer
pgig05225
Hepatocellular carcinoma
pgig05226
Gastric cancer
pgig05231
Choline metabolism in cancer
pgig05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
120584753 (RPS6KB2)
04350 TGF-beta signaling pathway
120584753 (RPS6KB2)
04371 Apelin signaling pathway
120584753 (RPS6KB2)
04066 HIF-1 signaling pathway
120584753 (RPS6KB2)
04151 PI3K-Akt signaling pathway
120584753 (RPS6KB2)
04152 AMPK signaling pathway
120584753 (RPS6KB2)
04150 mTOR signaling pathway
120584753 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
120584753 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
120584753 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
120584753 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
120584753 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
120584753 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
120584753 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120584753 (RPS6KB2)
05205 Proteoglycans in cancer
120584753 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
120584753 (RPS6KB2)
05231 Choline metabolism in cancer
120584753 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
120584753 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
120584753 (RPS6KB2)
05212 Pancreatic cancer
120584753 (RPS6KB2)
05225 Hepatocellular carcinoma
120584753 (RPS6KB2)
05226 Gastric cancer
120584753 (RPS6KB2)
05221 Acute myeloid leukemia
120584753 (RPS6KB2)
05224 Breast cancer
120584753 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
120584753 (RPS6KB2)
05163 Human cytomegalovirus infection
120584753 (RPS6KB2)
05165 Human papillomavirus infection
120584753 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
120584753 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
120584753 (RPS6KB2)
01522 Endocrine resistance
120584753 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pgig01001
]
120584753 (RPS6KB2)
Enzymes [BR:
pgig01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
120584753 (RPS6KB2)
Protein kinases [BR:
pgig01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
120584753 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Pkinase_fungal
Kinase-like
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
120584753
NCBI-ProteinID:
XP_039696630
LinkDB
All DBs
Position
Unknown
AA seq
557 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEGEPEFSPADVCPLAELRAAGLEPVGHYEEVELTETSVNLGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGSNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSASPASSGGQEWGREAVSRSGQGQCRWEAHKAPFT
LHPPPATLHCREPEEDHGQDHQREAGAAPVPHPGCPRPRQKVSEAESQPADRGRPRGRCR
CAGGSGVTTRGWGCSGREFLREPRGGELVACLGALYPQRHPFFRHINWDDLLARRVDPPF
RPCLQSEDDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIREGFNFQ
PKLRSPRRLNSSPRTPISPLKLSPFEGFRPSPGPPEPMEPPLPPLLPPPPPSSTAPLPIQ
PPSGTKKSKRGRGRPGR
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtgtttgacctggacctggagacggaggaaggcagcgagggcgagggcgag
ccagagttcagccctgcggacgtgtgtccccttgccgagttgagggctgctggcctggag
cctgtgggacactatgaagaggtggagctcactgagaccagtgtgaacctgggccctgag
cgcattggaccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaag
gtgttccaggtgcgaaaggtgcagggcagcaacttgggcaaaatatacgccatgaaagtc
ctgaggaaggccaaaattgtgcgcaacgccaaggacacggcacacacacgggctgagcgg
aacattctagagtccgtgaagcaccccttcattgtggaactggcctacgccttccagact
ggtggcaaactctacctcatcctcgagtgcctcagtggcggcgagctcttcacacatctt
gagcgagagggcatcttcctggaagacacggcctgtttctacctagcagagatcacactg
gccctggggcacctccactcccaaggcatcatctaccgggacctcaaaccagagaacatc
atgctcaacagccagggccacatcaaactgacggactttggactctgcaaggagtcgatt
cacgagggcgctgtcacccacaccttctgtggcaccattgagtacatggcccctgagatt
ctggtgcgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtac
gacatgctcactggatcggcaagtccagcctcctcgggagggcaggagtgggggcgggag
gcggtctcccgctcagggcaggggcagtgccggtgggaggcccacaaggctccttttacc
ctccacccccctccagccacccttcactgcagagaaccggaagaagaccatggacaagat
catcaaagggaagctggtgctgcccccgtacctcaccccggatgcccgcgacctcgtcaa
aaagtttctgaagcggaatcccagccagcggatcgggggcggccccggggacgctgccga
tgtgcaggtgggtctggggtcaccacgagggggtggggctgttcgggcagagagttcctg
agggagccaagggggggtgaactggtggcatgtttgggggcactgtacccacagaggcac
cccttttttcggcacattaattgggatgatctcctggcccgccgcgtggacccccctttc
cggccctgtctgcagtcagaggacgacgtgagccagtttgacacccgcttcacacggcag
acgccagtggacagcccagacgacacggccctcagtgagagcgccaaccaggccttcctg
ggcttcacatacgtggcgccctccgtcctggacagcatcagagagggcttcaactttcag
cccaaactgcgctcccccagacgcctcaacagcagcccccggacccccatcagccccctg
aagttgtcaccctttgaggggttccggcctagccctggcccaccggagcccatggagccc
cctttacctcctctcctgccgccgccaccaccctcgagcactgcccctctccccatccaa
cccccctcggggaccaagaagtctaagaggggtcgcgggcgccctgggcgctag
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