Pteropus vampyrus (Indian flying fox): 120586318
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Entry
120586318 CDS
T07511
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig00020
Citrate cycle (TCA cycle)
pgig00190
Oxidative phosphorylation
pgig01100
Metabolic pathways
pgig01200
Carbon metabolism
pgig04714
Thermogenesis
pgig04932
Non-alcoholic fatty liver disease
pgig05010
Alzheimer disease
pgig05012
Parkinson disease
pgig05014
Amyotrophic lateral sclerosis
pgig05016
Huntington disease
pgig05020
Prion disease
pgig05022
Pathways of neurodegeneration - multiple diseases
pgig05208
Chemical carcinogenesis - reactive oxygen species
pgig05415
Diabetic cardiomyopathy
Module
pgig_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pgig_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
pgig_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
120586318 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
120586318 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
120586318 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
120586318 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
120586318 (SDHA)
05012 Parkinson disease
120586318 (SDHA)
05014 Amyotrophic lateral sclerosis
120586318 (SDHA)
05016 Huntington disease
120586318 (SDHA)
05020 Prion disease
120586318 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
120586318 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
120586318 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
120586318 (SDHA)
Enzymes [BR:
pgig01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
120586318 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
DAO
HI0933_like
FAD_binding_3
Motif
Other DBs
NCBI-GeneID:
120586318
NCBI-ProteinID:
XP_039698810
LinkDB
All DBs
Position
Unknown
AA seq
665 aa
AA seq
DB search
MSVVRALSRLPRARRLALTKAQRPAALQTGSRDFHFTVDGNKRSSAKVSDSISTQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCI
EDGSIHRLRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLAIRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLRHVHGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KVPPIKANAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQEHAAVFRVGSVLQEGCGKL
SQLYGELRHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKE
RIDEYDYSKPIQGQQQKPFEQHWRKHTLSYVDSRTGKVSLEYRPVIDKTLNEADCATVPP
AIRSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atgtcggtggtccgggcgttgtcgcggctcccgcgcgccaggcgcctggcgctgaccaag
gcgcagcgtccagcagccctgcagacaggaagtcgtgactttcacttcactgttgacggg
aataagaggtcgtctgctaaagtttcagattcgatttccacacagtacccagtagtggat
catgaatttgatgccgtggtggtgggcgccggaggcgcaggcttgcgagctgcatttggc
ctttcggaggcagggttcaacacggcctgtgtcacaaagctcttccccaccaggtcccac
accgtggcagcccagggaggaatcaatgctgctctggggaacatggaggaggacaactgg
aggtggcacttctatgacaccgtgaagggctccgactggctgggggaccaggatgccatc
cactacatgacagagcaggcccctgcctctgtggtcgagctggagaactacggcatgccg
ttcagcagaaccgaggacggcaagatctaccagcgcgcttttggcggacagagcctcaag
tttgggaaaggcgggcaggcccaccggtgctgctgcgtggccgaccgcaccggccactca
ctgctgcacacgttgtatggaaggtccttgcggtacgacaccagctatttcgtggagtac
ttcgccttggacctcttgatggagaatggggagtgtcgtggcgtcatcgcactttgcata
gaagacgggtccatccatcgcctaagagcaaagaacacggttgtagccactggaggctac
gggcgcacctacttcagctgcacgtcggcccacaccagcaccggcgacggcaccgccatg
atcaccagggcagggcttccctgccaggacttggaatttgttcagttccaccccacaggg
atatacggtgccggctgtctcatcacggaggggtgccgtggagagggcggcattctcatt
aacagtcaaggcgagaggttcatggagcggtacgcccccgtcgccaaggacctggcctcc
agagacgtcgtgtctcggtccatgaccctggagatccgtgagggcagaggctgtgggcct
gagaaagatcacgtctacctgcagttgcaccacctgcccccggagcagctggccatccgc
ctgcctggcatttcagagacagccatgatctttgcgggtgtggatgtcaccaaagagccg
atccctgtccttcccaccgtgcattacaacatgggtggcattcccaccaactacaagggg
caggttctgaggcacgtgcacggccaggaccaggtcgtgcccggcctgtacgcctgtggg
gaggccgcctgcgcctcggtgcacggcgccaaccgccttggggctaactcactgctggac
ctggtcgtctttggccgggcatgcgccctgagcatcgcggagtcctgcagacccggagat
aaagttcccccgattaaagcaaatgctggggaagaatctgtcatgaatcttgacaaattg
agatttgccgacgggagcataagaacatcggaattgcgactcagcatgcagaagtccatg
caggagcacgcggcggtgttccgggtgggcagcgtgctgcaggagggctgcgggaaactc
agccagctctacggggaactgaggcacctgaagacctttgaccgaggaatggtctggaac
acggacctggtggagacgctggagctgcagaacctgatgctgtgcgcgctgcagaccatt
tacggggcggaggcccggaaggagtcgcgcggcgcccacgccagggaggactacaaggag
cggatcgatgagtacgattattccaagcccatccagggtcagcagcagaagccatttgag
cagcactggaggaagcacacgctttcctacgtcgatagcaggactgggaaggtctccctg
gaatacaggcctgtaatcgacaaaactttaaacgaggctgactgtgccacagtcccccca
gccattcgctcctactga
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