KEGG   Pteropus vampyrus (Indian flying fox): 120588349
Entry
120588349         CDS       T07511                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
pgig  Pteropus vampyrus (Indian flying fox)
Pathway
pgig01522  Endocrine resistance
pgig04010  MAPK signaling pathway
pgig04012  ErbB signaling pathway
pgig04014  Ras signaling pathway
pgig04024  cAMP signaling pathway
pgig04068  FoxO signaling pathway
pgig04071  Sphingolipid signaling pathway
pgig04137  Mitophagy - animal
pgig04140  Autophagy - animal
pgig04141  Protein processing in endoplasmic reticulum
pgig04210  Apoptosis
pgig04215  Apoptosis - multiple species
pgig04217  Necroptosis
pgig04310  Wnt signaling pathway
pgig04380  Osteoclast differentiation
pgig04510  Focal adhesion
pgig04530  Tight junction
pgig04620  Toll-like receptor signaling pathway
pgig04621  NOD-like receptor signaling pathway
pgig04622  RIG-I-like receptor signaling pathway
pgig04625  C-type lectin receptor signaling pathway
pgig04657  IL-17 signaling pathway
pgig04658  Th1 and Th2 cell differentiation
pgig04659  Th17 cell differentiation
pgig04660  T cell receptor signaling pathway
pgig04664  Fc epsilon RI signaling pathway
pgig04668  TNF signaling pathway
pgig04722  Neurotrophin signaling pathway
pgig04723  Retrograde endocannabinoid signaling
pgig04728  Dopaminergic synapse
pgig04750  Inflammatory mediator regulation of TRP channels
pgig04910  Insulin signaling pathway
pgig04912  GnRH signaling pathway
pgig04914  Progesterone-mediated oocyte maturation
pgig04917  Prolactin signaling pathway
pgig04920  Adipocytokine signaling pathway
pgig04926  Relaxin signaling pathway
pgig04930  Type II diabetes mellitus
pgig04931  Insulin resistance
pgig04932  Non-alcoholic fatty liver disease
pgig04933  AGE-RAGE signaling pathway in diabetic complications
pgig04935  Growth hormone synthesis, secretion and action
pgig04936  Alcoholic liver disease
pgig05010  Alzheimer disease
pgig05012  Parkinson disease
pgig05016  Huntington disease
pgig05017  Spinocerebellar ataxia
pgig05020  Prion disease
pgig05022  Pathways of neurodegeneration - multiple diseases
pgig05132  Salmonella infection
pgig05133  Pertussis
pgig05135  Yersinia infection
pgig05142  Chagas disease
pgig05145  Toxoplasmosis
pgig05152  Tuberculosis
pgig05161  Hepatitis B
pgig05162  Measles
pgig05166  Human T-cell leukemia virus 1 infection
pgig05167  Kaposi sarcoma-associated herpesvirus infection
pgig05169  Epstein-Barr virus infection
pgig05170  Human immunodeficiency virus 1 infection
pgig05171  Coronavirus disease - COVID-19
pgig05200  Pathways in cancer
pgig05208  Chemical carcinogenesis - reactive oxygen species
pgig05210  Colorectal cancer
pgig05212  Pancreatic cancer
pgig05231  Choline metabolism in cancer
pgig05415  Diabetic cardiomyopathy
pgig05417  Lipid and atherosclerosis
pgig05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pgig00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    120588349 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120588349 (MAPK10)
   04012 ErbB signaling pathway
    120588349 (MAPK10)
   04014 Ras signaling pathway
    120588349 (MAPK10)
   04310 Wnt signaling pathway
    120588349 (MAPK10)
   04668 TNF signaling pathway
    120588349 (MAPK10)
   04068 FoxO signaling pathway
    120588349 (MAPK10)
   04071 Sphingolipid signaling pathway
    120588349 (MAPK10)
   04024 cAMP signaling pathway
    120588349 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    120588349 (MAPK10)
   04137 Mitophagy - animal
    120588349 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    120588349 (MAPK10)
   04215 Apoptosis - multiple species
    120588349 (MAPK10)
   04217 Necroptosis
    120588349 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    120588349 (MAPK10)
   04530 Tight junction
    120588349 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    120588349 (MAPK10)
   04621 NOD-like receptor signaling pathway
    120588349 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    120588349 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    120588349 (MAPK10)
   04660 T cell receptor signaling pathway
    120588349 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    120588349 (MAPK10)
   04659 Th17 cell differentiation
    120588349 (MAPK10)
   04657 IL-17 signaling pathway
    120588349 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    120588349 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    120588349 (MAPK10)
   04920 Adipocytokine signaling pathway
    120588349 (MAPK10)
   04912 GnRH signaling pathway
    120588349 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    120588349 (MAPK10)
   04917 Prolactin signaling pathway
    120588349 (MAPK10)
   04926 Relaxin signaling pathway
    120588349 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    120588349 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    120588349 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    120588349 (MAPK10)
   04722 Neurotrophin signaling pathway
    120588349 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    120588349 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    120588349 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    120588349 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    120588349 (MAPK10)
   05231 Choline metabolism in cancer
    120588349 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    120588349 (MAPK10)
   05212 Pancreatic cancer
    120588349 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    120588349 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    120588349 (MAPK10)
   05161 Hepatitis B
    120588349 (MAPK10)
   05171 Coronavirus disease - COVID-19
    120588349 (MAPK10)
   05162 Measles
    120588349 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120588349 (MAPK10)
   05169 Epstein-Barr virus infection
    120588349 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120588349 (MAPK10)
   05135 Yersinia infection
    120588349 (MAPK10)
   05133 Pertussis
    120588349 (MAPK10)
   05152 Tuberculosis
    120588349 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    120588349 (MAPK10)
   05142 Chagas disease
    120588349 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    120588349 (MAPK10)
   05012 Parkinson disease
    120588349 (MAPK10)
   05016 Huntington disease
    120588349 (MAPK10)
   05017 Spinocerebellar ataxia
    120588349 (MAPK10)
   05020 Prion disease
    120588349 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    120588349 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120588349 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    120588349 (MAPK10)
   05415 Diabetic cardiomyopathy
    120588349 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    120588349 (MAPK10)
   04936 Alcoholic liver disease
    120588349 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    120588349 (MAPK10)
   04931 Insulin resistance
    120588349 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    120588349 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    120588349 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pgig01001]
    120588349 (MAPK10)
Enzymes [BR:pgig01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     120588349 (MAPK10)
Protein kinases [BR:pgig01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   120588349 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 120588349
NCBI-ProteinID: XP_039701733
LinkDB
Position
Unknown
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDMWSVGCIMGEMIKGAVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagt
aaaagcaaagttgacaaccaattctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatctaaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgctgtgcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacacatgccaagagagcttaccgggaactagtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctcctataccaaatgttgtgtggcatcaagcacctc
cactctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctcgactttggactggccaggacggcaggcacaagcttcatgatg
actccttatgtggtgacacgttattacagagcccccgaggtcatcttgggaatgggctac
aaggagaacgttgacatgtggtcagtagggtgcatcatgggagaaatgataaaaggtgca
gtgctgtttcctggcactgatcatattgaccaatggaacaaggtaattgagcaactagga
acaccgtgtccggaattcatgaagaaattgcaacccacagtgagaaactatgtggagaat
cggcccaagtatgccggactcaccttccccaagctctttccagattccctcttcccagcg
gattctgagcacaataaactcaaagccagccaagccagggacttgttgtcaaagatgcta
gtcattgacccagccaaaaggatatcagtggatgacgctttacagcacccatatatcaat
gtctggtatgaccctgccgaagtggaggcgcctccacctcagatatatgacaaacagttg
gatgaaagagaacacaccattgaagaatggaaagaacttatctacaaggaagtaatgaat
tcggaagaaaagactaaaaatggtgtcgtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccttcctcgtccgtcaatgacatctcctccatgtcc
actgaccagaccctggcatctgacactgacagcagcctggaagcctcggcgggacccctg
ggttgttgcaggtga

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