KEGG   Pteropus vampyrus (Indian flying fox): 120589895
Entry
120589895         CDS       T07511                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X1
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
pgig  Pteropus vampyrus (Indian flying fox)
Pathway
pgig04010  MAPK signaling pathway
pgig04015  Rap1 signaling pathway
pgig04218  Cellular senescence
pgig04620  Toll-like receptor signaling pathway
pgig04664  Fc epsilon RI signaling pathway
pgig04668  TNF signaling pathway
pgig04714  Thermogenesis
pgig04750  Inflammatory mediator regulation of TRP channels
pgig04912  GnRH signaling pathway
pgig04935  Growth hormone synthesis, secretion and action
pgig04936  Alcoholic liver disease
pgig05014  Amyotrophic lateral sclerosis
pgig05022  Pathways of neurodegeneration - multiple diseases
pgig05132  Salmonella infection
pgig05135  Yersinia infection
pgig05145  Toxoplasmosis
pgig05161  Hepatitis B
pgig05169  Epstein-Barr virus infection
pgig05170  Human immunodeficiency virus 1 infection
pgig05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pgig05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pgig00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120589895 (MAP2K3)
   04015 Rap1 signaling pathway
    120589895 (MAP2K3)
   04668 TNF signaling pathway
    120589895 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    120589895 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    120589895 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    120589895 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120589895 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    120589895 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    120589895 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    120589895 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120589895 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    120589895 (MAP2K3)
   05161 Hepatitis B
    120589895 (MAP2K3)
   05169 Epstein-Barr virus infection
    120589895 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120589895 (MAP2K3)
   05135 Yersinia infection
    120589895 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    120589895 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    120589895 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    120589895 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120589895 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    120589895 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pgig01001]
    120589895 (MAP2K3)
Enzymes [BR:pgig01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     120589895 (MAP2K3)
Protein kinases [BR:pgig01001]
 Serine/threonine kinases: STE group
  STE7 family
   120589895 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1
Other DBs
NCBI-GeneID: 120589895
NCBI-ProteinID: XP_039703561
UniProt: A0A6P3RFH1
LinkDB
Position
Unknown
AA seq 347 aa
MESPASSQPASIPQSKGKSKRKKDLRISCVSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNTQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPVERMSYLELMEHPFFTLHKTKKTDITAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcccgcctcgagccagcctgccagcataccccagtccaaaggaaaatctaag
aggaagaaggatttacgaatatcctgtgtgtccaagccacctgtgcccaaccctacgcca
ccccggaacctggactcccggaccttcatcaccattggagataggaactttgaggtggag
gctgatgacctggtgaccatctcggaactgggacgtggagcctatggggtggtagagaag
gtgcggcatgcccagagcggcaccatcatggctgtaaagcggatccgggccactgtcaac
acacaggagcagaagcgtctgctcatggacttggacgtcaacatgcgtacagtcgactgc
ttctataccgtcaccttctatggagccctcttcagagagggagatgtatggatctgcatg
gagctcatggacacatccttggataagttctaccggaaggtgcttgataaaaacatgacg
attccagaggacattcttggggagattgctgtgtctattgtgagggcactggagcatctg
cacagcaagctgtccgtgatccacagagatgtgaagccatctaatgtcctcatcaacaag
gagggccatgtgaagatgtgcgattttgggatcagcggctacttggtggattctgtggcc
aagacgatggatgctggctgcaagccctatatggctcctgagagaatcaacccggagctg
aaccagaagggctacaacgtcaagtctgatgtctggagcctcggaatcaccatgatcgag
atggccattctacggtttccttatgagtcttgggggaccccgttccagcaactgaagcaa
gtggtggaggagccgtccccccagctcccagctgaccgtttttcccctgagtttgtggac
ttcaccgcacagtgcctaagaaagaaccccgtggagcgcatgagctacctggagctgatg
gaacatcctttcttcaccttgcacaaaaccaagaagacagacatcactgcttttgtgaag
gaaatcctgggagaggactcatag

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