KEGG   Pteropus vampyrus (Indian flying fox): 120600014
Entry
120600014         CDS       T07511                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pgig  Pteropus vampyrus (Indian flying fox)
Pathway
pgig04010  MAPK signaling pathway
pgig04015  Rap1 signaling pathway
pgig04218  Cellular senescence
pgig04380  Osteoclast differentiation
pgig04620  Toll-like receptor signaling pathway
pgig04664  Fc epsilon RI signaling pathway
pgig04668  TNF signaling pathway
pgig04750  Inflammatory mediator regulation of TRP channels
pgig04912  GnRH signaling pathway
pgig04935  Growth hormone synthesis, secretion and action
pgig04936  Alcoholic liver disease
pgig05014  Amyotrophic lateral sclerosis
pgig05022  Pathways of neurodegeneration - multiple diseases
pgig05132  Salmonella infection
pgig05135  Yersinia infection
pgig05145  Toxoplasmosis
pgig05161  Hepatitis B
pgig05163  Human cytomegalovirus infection
pgig05167  Kaposi sarcoma-associated herpesvirus infection
pgig05169  Epstein-Barr virus infection
pgig05170  Human immunodeficiency virus 1 infection
pgig05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pgig05417  Lipid and atherosclerosis
pgig05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pgig00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120600014 (MAP2K6)
   04015 Rap1 signaling pathway
    120600014 (MAP2K6)
   04668 TNF signaling pathway
    120600014 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    120600014 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    120600014 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    120600014 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    120600014 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    120600014 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    120600014 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    120600014 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    120600014 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    120600014 (MAP2K6)
   05161 Hepatitis B
    120600014 (MAP2K6)
   05163 Human cytomegalovirus infection
    120600014 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    120600014 (MAP2K6)
   05169 Epstein-Barr virus infection
    120600014 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    120600014 (MAP2K6)
   05135 Yersinia infection
    120600014 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    120600014 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    120600014 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    120600014 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    120600014 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    120600014 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    120600014 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pgig01001]
    120600014 (MAP2K6)
Enzymes [BR:pgig01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     120600014 (MAP2K6)
Protein kinases [BR:pgig01001]
 Serine/threonine kinases: STE group
  STE7 family
   120600014 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 120600014
NCBI-ProteinID: XP_039715160
UniProt: A0A6P3QYW1
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLIIGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaggaagcattt
gaacagcctcagaccagttccacgccacctcgagatttagactccaaagcgtgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggaacctataatggagctggga
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacggtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtccttttacggtcaccttttatggcgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacatcgctagataaattctac
aaacaagtgattgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcgttagaacatttacacagtaagctgtctgtcattcatcgagatgtc
aagccttccaatgtgctgatcaatactctgggccaggtgaagatgtgcgattttggaatc
agtggctaccttgtagactccgtcgctaaaacgattgatgcaggatgcaaaccatacatg
gcccctgagagaataaacccagagctcaaccagaagggctacagcgtgaagtccgacatt
tggagtctgggcataacgatgattgagttggccatccttcggtttccctacgattcatgg
ggaactccctttcagcagctcaaacaagtagtagaggagccgtcgccacagctcccagca
gacaagttctccgaagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggccaacgtatccagagcttatgcaacatccatttttcaccctacatgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattattggagactaa

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