Pteropus vampyrus (Indian flying fox): 120600114
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Entry
120600114 CDS
T07511
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig04140
Autophagy - animal
pgig04141
Protein processing in endoplasmic reticulum
pgig04210
Apoptosis
pgig04932
Non-alcoholic fatty liver disease
pgig05010
Alzheimer disease
pgig05012
Parkinson disease
pgig05014
Amyotrophic lateral sclerosis
pgig05016
Huntington disease
pgig05017
Spinocerebellar ataxia
pgig05022
Pathways of neurodegeneration - multiple diseases
pgig05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
120600114 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
120600114 (ERN1)
09143 Cell growth and death
04210 Apoptosis
120600114 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
120600114 (ERN1)
05012 Parkinson disease
120600114 (ERN1)
05014 Amyotrophic lateral sclerosis
120600114 (ERN1)
05016 Huntington disease
120600114 (ERN1)
05017 Spinocerebellar ataxia
120600114 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
120600114 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
120600114 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
120600114 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pgig01001
]
120600114 (ERN1)
Enzymes [BR:
pgig01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
120600114 (ERN1)
Protein kinases [BR:
pgig01001
]
Serine/threonine kinases: Other
IRE family
120600114 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
120600114
NCBI-ProteinID:
XP_039715352
LinkDB
All DBs
Position
Unknown
AA seq
1003 aa
AA seq
DB search
MGPKARLRTAQCSFQIILDFFSRLDCRLVICASFYTKESFTDNRTQILGSPSTVTLPETL
LFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEG
LTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVVDLLTGEKQQTLSSAFADSLCPSTS
LLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSE
SGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPK
ETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGEC
VITPSTDLKFDPGLKGKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIP
ADSEKKSFEEVIHLVDQTSETAPTTVSQDVEEKFANAPAKPEAPMDSMLKDIATIILSTF
LLIGWVAFIITYPLSMHQQQQRQHQQFQKELEKIQLLQQQQLPFHAPGDVAPDAELLDSS
GLYSESSGTSSPSTSPRASNHSLHSSGSASRTGASPFLEQDDEDEETSMVMVGKISFCPK
DVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTERD
RQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNI
LLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTCT
VDIFSAGCVFYYVVSEGSHPFGKSLQRQANILLGAYSLDCLHSEKHEDVIARELIEKMIA
MDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDW
RENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVRYFT
SRFPHLLSHTYRAMELCSHERLFQPYYFHPPPEPQPPVTPDAL
NT seq
3012 nt
NT seq
+upstream
nt +downstream
nt
atgggacccaaggcaagactgagaaccgcgcagtgttctttccaaattattttggacttc
ttttcacgtctcgattgccggcttgtaatttgtgcatctttctacacaaaagaaagcttt
accgacaacagaacgcaaattttgggaagtcccagcacagtgactcttcctgaaaccctg
ttgttcgtgtcaaccctggatggaagtttgcatgctgtcagcaagcggacaggctccatc
aaatggactttaaaagaagatccagttctgcaggttccaacccacgttgaagaacctgcc
ttcctcccagatcccaatgatggcagcctgtacacacttgggggcaagaataacgaaggc
ctgacgaaacttccctttacgatcccagagttggtacaggcatccccgtgccgaagttca
gatggaatcctctacatgggtaaaaagcaggacatttggtatgtggttgaccttctgacc
ggggagaagcaacagactttgtcatcagcctttgcagatagtctctgcccatcaacctct
cttctgtaccttggacgaacagagtacaccatcaccatgtacgacaccaaaacccgagag
ctccggtggaacgccacctacttcgactacgcagcctcgctgcccgaggacgacgtggac
tataagatgtcccattttgtgtccaatggcgatgggctggtggtgactgtggacagtgaa
tctggcgacgtcctgtggatccaaaactacgcttcccctgtggtggccttttatgtctgg
cagcgggagggtctgaggaaggtgatgcacatcaacgtcgctgtggagaccctgcgctat
ctgaccttcatgtctggggaggtggggcgcatcaccaagtggaagtaccccttccccaag
gagacggaggccaagagcaagctgacgcccaccctctatgttggtaaatactctaccagc
ctctacgcctccccctcaatggtccacgagggggtcgccgttgtgccccgaggcagcact
cttcctttgctggaaggcccccagaccgacggtgtcaccattggggacaaaggggagtgt
gtgatcacacccagcacggacctaaagtttgaccctgggctcaaagggaagaacaagctc
aactatttgaggaactactggcttctgataggacaccacgaaactcctctctccgcgtct
actaagatgctggagagattccccaacaacctgcccaaacaccgggaaaatgtgattcct
gctgactcagagaagaagagctttgaggaagttatccacctggtggaccagacctcagag
actgcacccaccaccgtttctcaggacgtggaggagaagttcgctaacgcccccgccaag
cctgaggcccccatggattccatgctcaaggacatagccaccatcatcctgagcaccttc
ctgctcatcggctgggtggccttcatcatcacctaccccttgagcatgcatcagcagcag
cagcgccagcaccagcagttccagaaggaactggagaaaatccagctcctgcaacagcag
cagctgcccttccacgcccccggggacgtggctccggacgccgagctcctggactcatct
ggcttgtattcggagagctcgggcaccagcagccccagcacgtcccccagagcctccaac
cactcgctgcactccagcggctctgcctccaggactggcgccagccccttcctggagcaa
gatgacgaggacgaggaaaccagcatggtgatggttgggaaaatttcattctgccccaag
gatgtcctgggccacggagcggagggcacaatcgtgtaccggggcatgttcgacaaccgt
gacgtggcggtcaagcggatccttcccgagtgcttcagtttcgcagaccgcgaggtccag
ctgctgcgagaatcagacgagcacccgaacgtgatccgctacttctgcacggagagggac
cggcagttccagtacattgccattgaactgtgcgcggccactctgcaggagtacgtggag
cagaaggactttgcccaccttggcctggagcccatcaccttgctgcagcagaccacctcg
ggcctggcccacctgcactctctcaacattgttcacagagacctaaaaccccacaacatc
ctcctctccatgcccaatgcacatggaaggatcaaggccatgatctctgactttggcctc
tgcaagaagctggcagtgggtagacacagcttcagccgccgttcaggggtgcccggcaca
gaaggctggattgctccagagatgctgagtgaagactgtaaggagaaccccacctgcaca
gtggacatcttctctgcgggctgcgtcttttactatgtggtgtctgagggcagccaccct
tttggcaagtccctgcagcggcaagcaaacatcctcctgggcgcctacagcctcgactgc
ttacactctgagaagcacgaagatgtcatcgccagggaattgatcgagaagatgatcgcg
atggaccctcagaagcgcccctcggcgaagcacgtgcttaaacacccgttcttctggagc
ctcgagaagcagctccagttctttcaggacgtgagtgaccgcatagagaaggaatccctg
gatggcccgatcgtgaagcagctggagagaggcgggagagccgtggtgaagatggactgg
agggagaacatcaccgtccctctccagacagatctgcgtaaattcagaacctataaaggc
ggctctgtcagagatctcctccgagccatgagaaataagaagcaccactaccgggagctc
cccgcagaggtacgggagaccctgggctccctccccgatgacttcgtgcgctacttcaca
tcccgcttcccccatctgctctcacacacctaccgggccatggagctgtgcagccacgag
aggctcttccaaccctactacttccacccgcccccggagcctcagcccccagtgactcca
gacgccctctga
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