Pteropus vampyrus (Indian flying fox): 120602732
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Entry
120602732 CDS
T07511
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
120602732 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
pgig03021
]
120602732 (SETX)
Enzymes [BR:
pgig01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
120602732 (SETX)
5.6.2.5 RNA 5'-3' helicase
120602732 (SETX)
Transcription machinery [BR:
pgig03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
120602732 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
SLFN-g3_helicase
AAA_16
Helicase_RecD
nSTAND3
TniB
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
120602732
NCBI-ProteinID:
XP_039718853
LinkDB
All DBs
Position
Unknown
AA seq
2683 aa
AA seq
DB search
MSTCCWCTPGGVSTVDFLKLYASETPSSEFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETRRLIIHFEKSMRAEIEDDDELYIVDNNGETQLFDFTGQDFENKLRVPLLEILKY
PYLLLHARVNELCVEALCRMEQANCSFQVFEKHPGVYLFLVHPNEMVRRWAILTAKGLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLVLLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKENDFMQLILHTMERQSDDDSGDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNRSYNREIQSIRNSSVRTKLEPESCMDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTVVVCDKVTEFFFLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGSGSKGTPMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFRDKLNLFLRGNLSLGWQLTSQETQELQTCLKQIIRNIKFKVP
QCSAIVDLTPPCKILPASCDKEENEQVGKKCKNMLCVESSSPTFSKEPMKADAYQLQESI
LSKASSAVEEDNEPNYIKDLKLEDHLSAESCLKQSSKNLFAGRAQDQVKMRTGKQKSVKD
NSLYTSKNCTARNGPERGCGRGIILSTHSPTDSSADTQEKMSTSNGDFSSKDGVLGKTSK
AKSKAQKDEICAKLSCVIKKPHRKNTSVNSTVKFEGNLAASNVENFCSRKDAGGQKGDSF
MHSLSSGSDGILDNKNGEQKAHNSLLLKKKQVKSEELDVFSSHENDCQIQECDVGNKDLV
LFTETTNTFMHKTSPFKSPGAVLESREKRVSKNTDFREQAPSISPKSDTLTDSQVDRDLH
KLSRIAQASVIKFPSDSNQRSSSQLQRKVKDKSFTANQSNVGDTCRGQIIIISDSDDDDE
DADERILEFEKLKHIKQDKVSIKKEGPGPRTSEAHTNTERKPIKEEKPASPLEFEECDSQ
VFEFESQHEVFSVWQDQKTDDSSVPEDGKSSCLTHIVDITNDWGYETDYPVSEEVAEVTK
DVENAEPRSSRVSVEKFCEIEVRRSKRKQFEKPVAEDPLRPSSSARNEDQSDILNERELT
ENDLKIADVRTTTPDARVQRATAAALKKSPPKLRAYSKPIRRVPVSKAAKKTHSDARKGQ
SKSSNYISCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRRAFELSQRSLEYIVQLRDH
GKTVGVVDTRKKTKLISPQTLPVKNKKLLANQDLQLQRQVRPKSQQNRQGVFDCESTDAA
RAGPDAAQIPDVFVAESARSDCSNKAGAEVIASSNGRQSVTCVSSEQEPMKAKFISQETE
DPCPLNQRECVMANGGILTHERALSTSEDPVGGGDLTTPHLDVATLNKGEPASNSDMEED
NIFLTQCDPEDMDLCSQMQQNDNDKLIEVVHGKDTVQVGEDSLSRPPLESLSSTKCKYRD
CAETLKNQGEYCSKHCEAKAADEDVFRKPGLPLSAAKPLRPSTTKIFSSSSTSRIAHLSR
SLEKASALLPALKNKSNGAQSVLKAPPPAPLAPPQKPVVEVKSLCNILNSPPSNNSSRQG
YRLPFSESRPFSSSPVNMLLSSQSISDAFVKEILKWKYEMFLNFDQCGPPASLCQSISRP
VPVRFQDCGDYFDVFFPLMILNTFETVAQEWISSPNKEKFYQLHLRKFPADYKKYWELVV
YLDEGELAKQLHPKENDLVFLVPGTLNGEEHGLEHSLLQEPHEPYCGYVHKFRRTSVMRN
GKAECCLSIQTQDNVAVNLSEFVKCTVISSLVTTQRKLKAMSLLSGRNQLARAILNPNPM
DFCTKDLLTTTSERITLYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKT
IVGLLYRLLTENQRRGHPDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKK
NPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSYVQEMHKRKEYLDHQLD
DLSRQRALCRGGREIQRQELDEKIARVSKERQELASKIKEVQGRPQKTQSNVILESHIIC
CTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLP
PTVISMKAQEYGYEQSMMARFYKLLEENVEHNVVGRLPVLQLTVQYRMHPDICLFPSNYI
YSRSLKTNRQTETIRCSSDWLFQPYLVFDVGDGAERRDNDSYVNVQEIKLVMEIIKLIKD
KKKDVSFRNIGIITHYKAQKMMIQKELDKEFDGKGPAEVDTVDAFQGRQKDCVIVTCVRA
NAMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCD
KNYKHDAMKILKLKPVLTRSLTHPLTVTPEVARPQGGDLPGTKPDSSFTKVAFALSLCHL
ASDSKEALATVAAKDSERPPAKDQPRDPRLFRRMGVSPETKGKCLQDPQPLSPQYPGATP
PLGEPGCVSPQALGSLAEQPSATGSSHRPRVPSEPPAAGTDAASDQRKCDQEGEHGHRRE
TRASSEGNQERRGPAGRHTKRNSSWDGRVPEREDRSSKKRKLP
NT seq
8052 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgttggtgtacgccaggtggcgtttccaccgtcgacttcctgaagctc
tatgcgtccgagaccccatccagtgaatttcagaccgccgacgaagacctctgctactgc
ttggagtgtgtggccgagtaccacaaggccagggatgagctgccgttcttgcacgaggtt
ttatgggaattagaaacccgacgtctcataattcattttgaaaaatccatgagggcagaa
atcgaagatgatgatgaattatacatagtggacaacaatggagagacacagctgtttgac
tttactggccaagactttgaaaataagcttcgggttcctcttcttgaaatcctgaaatat
ccttatctgctcttacacgcacgtgttaatgaattatgcgttgaagcactttgtcggatg
gaacaggccaattgttcctttcaggtttttgaaaagcatcctggggtctatttgtttttg
gtccatcccaatgaaatggttcggcgctgggccatcctgaccgcaaaaggcctggggaaa
gtggacagggacgattactatgacttacaggaggttttgacttgcctctttaaagtcatc
gagttggggcttttagaaagtccagacatttatacttcctctgtcctcgagaagggtaaa
ctggttcttctgccctcacacatgtatgatactacaaactacaaaaactattggctaggt
atctgcatgttgcttaccattcttgaagagcaggccatggattcactgttgttgggctcg
gacaaagagaacgattttatgcagttgatacttcacaccatggagaggcagtcagacgac
gatagtggggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt
ggatccaaggtctgggggcagctcattgaccctatcgaggcatttcaaaccatcatcaac
aaccggagctacaaccgagagatccagagtatccggaacagctctgtgaggaccaagtta
gaaccggagtcgtgtatggatgatatggtgacttgcagccagattgtatacaattataat
cctgaaaagaccaaaaaggattcaggctggagatcagccatttgcccagattattgccct
aacatgtacgaagagatggaaacattagccagcgtgcttcaatcagacatcggtcaagac
atgcgtgttcacaacagcacattcctgtggttcattccgttcgttcagtccctcatggat
ctgaaggatctgggcgtggcctacatagtagaggttatccatcatctgcactcggaagtc
aaagatgtcctcaaccagacagttgtcgtgtgtgacaaagtcactgaatttttttttcta
attttggtgtcagtgatcgaactacataggaataaaaaatgcttgcatttgctgtgggtg
agctcccagcagtgggtggaggctgtcgtgaagtgtgccaagctcccgaccactgccttt
gcacggagctcggagaagtcatccggcagcggctccaaaggaacaccgatgatatcatct
ctgtctctccattcaatgccatctaactccgtacagctcgcttgcgtgcagctgattaga
agtctccttaaagaaggttaccagcttgggcagcagactctttgtaagcggttcagggat
aagctcaacttattcctgcgagggaacttatctctaggctggcagttgactagtcaggaa
acccaggagttgcaaacttgtttaaagcaaatcattagaaacatcaaattcaaagtacca
caatgtagcgctattgtggacctgactcctccatgtaagattcttccggcatcttgtgat
aaagaagaaaatgagcaagtagggaagaagtgtaaaaacatgctctgtgtggaaagttcc
agcccaacgttttctaaagaaccaatgaaagctgacgcgtatcagctgcaagagagtatc
ttgagcaaagcaagtagcgctgtggaagaggataatgagccaaattacattaaagatttg
aaactagaggaccatctctcagctgagtcatgcttaaagcagagtagtaaaaaccttttc
gctggaagagctcaagatcaagttaaaatgcgtacggggaagcaaaagtctgtcaaagac
aattctttatacacatcaaagaactgtactgcaaggaatggtccagaaagaggatgtggc
agaggaataatactgtcaacacattcgccaactgattctagcgctgatactcaggagaag
atgtccacatcaaatggggatttctcttcgaaggatggtgttcttggcaaaacttcaaaa
gcaaaatctaaggcccagaaagatgaaatctgtgctaagttatcgtgtgtaataaagaag
ccacacaggaaaaacacctcggtcaatagtactgtgaagttcgaaggaaacctggccgca
tctaacgttgagaatttctgttcaaggaaagacgcaggaggtcagaaaggggatagcttc
atgcacagtctctcttcaggctccgacggtattctggataataaaaatggagaacaaaaa
gctcacaacagtttattgctgaaaaagaaacaggtgaagagtgaagagttagatgttttt
tcttctcatgaaaatgattgtcaaatacaggaatgtgatgtcggcaataaagatttggtc
ctatttacagaaacgaccaatactttcatgcataaaacatctccctttaaaagtcccggg
gctgtacttgaatcaagggagaagagagtcagcaagaatactgactttagagaacaggcc
cctagcatcagccctaagtctgacaccttaacagattctcaggtagacagagacctccac
aaattatctcgaatagctcaagccagtgtcattaaatttccatcagattcaaatcaaaga
agctcatcccagctacaaagaaaagtgaaagacaaaagtttcacagccaaccaaagtaat
gtcggggacacctgccgtggtcaaattattattatttcagattccgatgatgatgatgaa
gatgctgatgaaagaattctggagtttgagaaattaaaacacattaaacaagataaagta
agcattaagaaagaaggcccagggccgcgtacatcagaagctcatacgaacacagaaagg
aagccgatcaaagaagagaagccagcttcccctttagagtttgaggagtgcgactcgcag
gtgttcgagtttgaaagccaacatgaagtgttttcagtctggcaagatcagaaaacagac
gacagttcagttccagaggacggaaagagctcctgcttgactcacattgtcgatatcaca
aatgactggggctacgagacagattatcctgtttctgaagaagttgccgaagtcaccaag
gacgtcgaaaatgcggagccacggagcagtcgtgtttccgttgagaaattttgtgaaatt
gaagtaagaagatctaagagaaaacaatttgaaaagcctgtggccgaagatcctttaagg
ccttcgtcttctgccagaaatgaggaccagtctgacatcctcaacgagagagagctgact
gaaaacgatcttaaaattgcagacgtgcggacgacgacccctgatgcgcgtgtccagcgg
gccaccgcggccgccctgaagaagtccccgcccaagctgcgcgcctactccaaacccatc
cggagggtccccgtgtccaaagccgcaaagaagacacattcggatgccagaaaggggcag
agtaaaagttcaaattacataagctgtaggacaactcctgccatcgtgccaccaaagaaa
tttcgccagtgtcctgaacccacctccacggttgagaagctgggtctgaaaaaggctccc
cgcagggcgtttgagctgtctcagcggtctttggagtacatagttcagctgcgtgaccat
ggcaaaaccgttggtgtcgtcgacacccgaaaaaagactaaattgatctctcctcagact
cttcctgtcaaaaataagaaactgcttgcaaatcaagatcttcagttgcaaaggcaggtg
agacccaaatcacagcaaaacagacaaggagtttttgactgtgaaagcacagatgccgcg
agagcgggcccagatgcggcacagattcctgacgtgttcgtagcagaatcagctaggtca
gattgtagtaacaaagcgggagctgaggtcatcgccagcagtaatggaagacagtcagtg
acatgcgtgtcttccgaacaagagcccatgaaagcgaaattcatttcccaggagaccgag
gatccttgtcccttaaaccagcgtgagtgtgtcatggcaaatggagggatactgacgcat
gaaagagctctctctacttcagaggaccctgtaggtggaggtgacctaacgacacctcat
ttagacgtggcaactttgaacaagggagagcccgcatccaacagtgacatggaggaagat
aatatatttttaacccagtgcgatcctgaagatatggatttatgttctcagatgcagcag
aacgataatgacaaactcattgaagtagttcatggaaaagatacagtccaggtaggagaa
gattcactcagtcggcctcccttggagtctttgagcagcacaaaatgtaagtacagagat
tgtgccgaaactctgaaaaaccagggcgagtactgctcgaaacactgcgaagccaaagca
gcggatgaagacgtgtttcggaagccgggcctgcccctttccgcggctaaacccctgaga
ccgtccacgacgaagatttttagctcaagtagtacctcacgaattgctcatctttcccgc
tctttggaaaaagcctccgcgctcctcccagctttaaaaaataagtcaaacggggcacag
tccgttttgaaagcgccaccgccagcccctctggcgcctcctcagaagccagtggttgaa
gtgaagagtttgtgcaacattcttaattctccaccttcgaataattccagcaggcaaggt
tacagacttccgttcagtgaaagcagacctttttcttcttctccggtaaacatgctcttg
tcctcacagtccatctccgacgccttcgtgaaagagatcctcaaatggaagtatgaaatg
tttttgaacttcgatcagtgcgggcccccagcaagtctctgtcagtccatctcaagacct
gtgcctgtcaggtttcaagattgtggagattattttgatgtgtttttccctttgatgata
ttgaatacttttgaaacagtagcacaggaatggatcagctctccaaataaagaaaaattc
tatcagctgcatttacgaaaatttcctgcagattataaaaagtactgggagctcgtggtt
tatcttgatgaaggcgaactagctaaacagctccacccaaaggagaacgatttggtgttt
ttggtccctggaacactgaacggagaggagcacggcctggagcacagcctcctgcaggag
ccgcacgagccttactgtggttatgtgcacaagtttcgccgcacttcagtcatgcgtaat
gggaaagctgagtgttgcctttccatccagactcaagataacgtggcggtcaacttaagt
gaatttgtgaaatgcactgtaatcagttctctggtaactacacaaaggaagttgaaagcc
atgtctttgttgagtggtcggaaccagctggctagagctattctgaatccaaaccccatg
gacttctgtacaaaagatttactgacgacaacatctgagagaattaccctctacttaaaa
gatttcaatgaagaccaaaagaaagccatagaaactgcatatgccatggtgaaacactcc
ccatctgtcgccaagatctgtctgattcacggaccacctggaacgggaaaatccaaaacc
attgtcggcctgctgtaccgcctgctgacggagaaccagaggagggggcatcccgatgaa
aactccaacgccaagatcaagcagaaccgcgtcctggtgtgtgcgccttccaacgcggcc
gttgatgagctcatgaagaaaatcatcctcgaattcaaagagaaatgtaaagacaagaag
aatcctttgggaaactgtggagatataaacttagtacgtctgggtccagaaaagtccatt
aataatgaagtcctgaaattcagcttggacagccaggttaaccacagaatgaaaaaagac
ttaccttcttatgtccaggagatgcacaaaagaaaggaatatctggatcatcaactcgat
gacctttcccgccagcgtgctttatgccgaggtgggagggaaatacagagacaagaacta
gacgaaaaaattgccagagtttcaaaagaaaggcaggaacttgcttctaaaattaaagag
gttcaaggccgcccacagaaaacacagagcaatgtcatcttggagtcccacatcatctgc
tgcacactgagcacaagtggcggtttattgctcgagtccgcttttcggggacagggaggg
gttcccttcagttgcgtcattgtcgatgaggccgggcagtcttgtgaggtggaaaccctc
accccactcatccaccgctgcaacaagcttatcctcgtgggggatcccaagcagctccct
cccaccgtcatctctatgaaggcccaggagtatggctacgagcagtcgatgatggcccgc
ttctacaaactgctggaggagaatgtggagcacaatgtggtgggcaggctgcccgtgctg
cagctcaccgtccagtaccgcatgcacccggacatctgcctcttcccgtccaattacatc
tacagcagaagcctgaagacgaacaggcagacggagaccatccggtgttcgtcagactgg
ctgttccaaccctacttggtgttcgacgtcggagacggcgcagagagacgggacaacgac
tcgtatgtaaatgttcaagaaataaaactggtaatggaaataattaaacttattaaagac
aaaaaaaaagatgtctctttccgaaacatcggcatcataacccattacaaggctcagaag
atgatgattcagaaggagttggacaaagaatttgatggaaaagggccagcggaagtagat
actgtggatgcattccagggtcgtcagaaagattgtgtcattgtcacgtgtgtcagagcg
aatgccatgcaaggctcaatcggatttctggcaagtttgcagagattgaacgtcaccatt
acacgagccaagtacagcctcttcatcctcggacacttgaggaccctgatggagaaccag
cactggaatcacctgattcaggacgcacagaagcgcggtgccattatcaagacctgtgac
aaaaactacaagcacgacgcaatgaagatcctgaaactcaagcccgtgctgacgagaagt
ctgacgcaccctctgaccgtcacccccgaggtggccagaccccagggcggcgacctgccc
ggcaccaagccggacagcagcttcaccaaggtagcttttgctttgtccctgtgccaccta
gcctctgactccaaagaggctcttgcgactgttgctgcaaaggactcggaaaggccgcct
gcgaaggaccagcctcgcgacccgcggctttttaggaggatgggcgtgagccctgaaacc
aaagggaagtgcctgcaggacccacagcccttgagcccccagtatcctggagccacgcct
cccctgggggagccaggctgcgtgagtccccaggctctgggcagcctcgcagagcagccc
tctgccaccggcagcagccacagacctcgcgtgccgagtgaacctccagccgccggcacc
gatgctgccagcgatcaaaggaaatgtgaccaggaaggggagcacggccaccggagagag
accagggcttccagcgaggggaaccaggagcggcggggccctgcgggccgtcacaccaag
aggaactcttcctgggatggccgggtgccggagagggaggaccgcagctccaagaagagg
aagctcccgtag
DBGET
integrated database retrieval system
