Pteropus vampyrus (Indian flying fox): 120604448 Help Entry 120604448         CDS       T07511                                  Symbol SOS2 Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism pgig  Pteropus vampyrus (Indian flying fox) Pathway pgig01521   EGFR tyrosine kinase inhibitor resistance pgig01522   Endocrine resistance pgig04010   MAPK signaling pathway pgig04012   ErbB signaling pathway pgig04014   Ras signaling pathway pgig04062   Chemokine signaling pathway pgig04068   FoxO signaling pathway pgig04072   Phospholipase D signaling pathway pgig04150   mTOR signaling pathway pgig04151   PI3K-Akt signaling pathway pgig04510   Focal adhesion pgig04540   Gap junction pgig04630   JAK-STAT signaling pathway pgig04650   Natural killer cell mediated cytotoxicity pgig04660   T cell receptor signaling pathway pgig04662   B cell receptor signaling pathway pgig04664   Fc epsilon RI signaling pathway pgig04714   Thermogenesis pgig04722   Neurotrophin signaling pathway pgig04810   Regulation of actin cytoskeleton pgig04910   Insulin signaling pathway pgig04912   GnRH signaling pathway pgig04915   Estrogen signaling pathway pgig04917   Prolactin signaling pathway pgig04926   Relaxin signaling pathway pgig04935   Growth hormone synthesis, secretion and action pgig05034   Alcoholism pgig05160   Hepatitis C pgig05161   Hepatitis B pgig05163   Human cytomegalovirus infection pgig05165   Human papillomavirus infection pgig05200   Pathways in cancer pgig05205   Proteoglycans in cancer pgig05206   MicroRNAs in cancer pgig05207   Chemical carcinogenesis - receptor activation pgig05208   Chemical carcinogenesis - reactive oxygen species pgig05210   Colorectal cancer pgig05211   Renal cell carcinoma pgig05213   Endometrial cancer pgig05214   Glioma pgig05215   Prostate cancer pgig05220   Chronic myeloid leukemia pgig05221   Acute myeloid leukemia pgig05223   Non-small cell lung cancer pgig05224   Breast cancer pgig05225   Hepatocellular carcinoma pgig05226   Gastric cancer pgig05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pgig00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     120604448 (SOS2)    04630 JAK-STAT signaling pathway     120604448 (SOS2)    04068 FoxO signaling pathway     120604448 (SOS2)    04072 Phospholipase D signaling pathway     120604448 (SOS2)    04151 PI3K-Akt signaling pathway     120604448 (SOS2)    04150 mTOR signaling pathway     120604448 (SOS2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     120604448 (SOS2)    04660 T cell receptor signaling pathway     120604448 (SOS2)    04662 B cell receptor signaling pathway     120604448 (SOS2)    04664 Fc epsilon RI signaling pathway     120604448 (SOS2)    04062 Chemokine signaling pathway     120604448 (SOS2)   09152 Endocrine system    04915 Estrogen signaling pathway     120604448 (SOS2)    04917 Prolactin signaling pathway     120604448 (SOS2)    04926 Relaxin signaling pathway     120604448 (SOS2)    04935 Growth hormone synthesis, secretion and action     120604448 (SOS2)   09156 Nervous system    04722 Neurotrophin signaling pathway     120604448 (SOS2)   09159 Environmental adaptation    04714 Thermogenesis     120604448 (SOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120604448 (SOS2)    05206 MicroRNAs in cancer     120604448 (SOS2)    05205 Proteoglycans in cancer     120604448 (SOS2)    05207 Chemical carcinogenesis - receptor activation     120604448 (SOS2)    05208 Chemical carcinogenesis - reactive oxygen species     120604448 (SOS2)    05231 Choline metabolism in cancer     120604448 (SOS2)   09162 Cancer: specific types    05210 Colorectal cancer     120604448 (SOS2)    05225 Hepatocellular carcinoma     120604448 (SOS2)    05226 Gastric cancer     120604448 (SOS2)    05214 Glioma     120604448 (SOS2)    05221 Acute myeloid leukemia     120604448 (SOS2)    05220 Chronic myeloid leukemia     120604448 (SOS2)    05211 Renal cell carcinoma     120604448 (SOS2)    05215 Prostate cancer     120604448 (SOS2)    05213 Endometrial cancer     120604448 (SOS2)    05224 Breast cancer     120604448 (SOS2)    05223 Non-small cell lung cancer     120604448 (SOS2)   09172 Infectious disease: viral    05161 Hepatitis B     120604448 (SOS2)    05160 Hepatitis C     120604448 (SOS2)    05163 Human cytomegalovirus infection     120604448 (SOS2)    05165 Human papillomavirus infection     120604448 (SOS2)   09165 Substance dependence    05034 Alcoholism     120604448 (SOS2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     120604448 (SOS2)    01522 Endocrine resistance     120604448 (SOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH IQ_SEC7_PH PH_19 RHG20_PH PH_10 PH_13 Motif Other DBs NCBI-GeneID:  120604448 NCBI-ProteinID:  XP_039721103 LinkDB All DBs Position Unknown AA seq 1332 aa AA seqDB search MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPSLSANEESLYYIEELIFQLLNKLC MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD IGLVSLCEDEPTSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKPSDI EKIFSNISDIHELTIKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI LSPKFSEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG CSSAEYRLKEKFVMRKIQICDKEDTCEYKHAFELVSKDENSIIFAAKSAEEKNNWMAALI SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHKDPDWFRDVSTCPNSPN TPPSTPSPRVPRRCYVLNSSQNNLAHPQAPPVPPRQTSSPHLPKLPPKTYKRELSHPPLY RLPLLENAETPQ NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg ggactgttagtctcggccctgcggaaggttcaggagcaagtacatcccagtctctcagct aatgaagaatctctgtattatattgaagagctgatttttcagctgcttaataaattatgc atggcccaaccaaggactgttcaagatgtggaggaacgagttcaaaaaacctttcctcat ccaattgataaatgggctattgctgatgcacagtctgccatagagaaacgaaaacgaaga aatcctctcttgctgcctgtggacaaaatccatccttcactgaaggaagttttagggtac aaagtggactaccatgtgtctttatatattgtggctgtactagagtatatctcagctgat attttgaaattggctggtaattatgtttttaatattcgacattatgaaatatctcagcag gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac ataggtttggtttctctttgtgaagatgaacctacttcttcaggtgaattaaactactat gatcttgtcagaactgaaattgcagaagaaagacagtatttacgggaactaaatatgatc ataaaagtttttcgagaagcctttctttctgacaaaaagctgtttaaaccttctgacatt gaaaagattttcagtaatatttcagatatacatgagttgactataaaacttttaggtttg attgaagacacagttgaaatgactgatgaaagcagtcctcatcctttagctggcagctgt tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt ctttcacctaaattcagtgaacatttcagtaagttgatggccagacctgcagtggctctt cactttcagtccattgctgatggttttaaagaagcagttcgttatgtccttccacgcctt atgctggtgccagtgtatcactgttggcactattttgaattattgaagcaattgaaagca tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat ctccaaggtagtatggaccgaatttacaagcagtattcaccccgacgccgacctggggat cctgtttgccctttttataatcgccaattaagaagcaagcatctggctattaaaaaaatg aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat gaatttattatggaaggtccattgacaagaattggtgctaaacatgaacggcatattttt ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcacgccttccaggt tgcagtagtgcagaatacagattaaaagaaaaatttgtcatgagaaaaatacaaatatgt gataaagaagatacttgtgagtacaaacatgcttttgagttagtatccaaagatgaaaac agtataatatttgcagctaagtccgctgaagagaaaaacaattggatggcagcacttatt tctcttcattatcgtagtactctagatcgaatgctagattcagtattattgaaagaagaa aatgaacaaccattgagattaccaagtcctgaagtatatcgttttgtggtaaaagactct gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa ggaggaactgtggtgaaattaattgaaaggttaacatatcatatgtatgcagatcccaat tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattgctaagc ttactaattgaacgatttgaaattccagagccagaacctactgaagccgataaattggca gtagagaaaggcgagcagccaattagtgcagaccttaaaaggtttcgcaaggaatacgtc caaccagtacaacttagaatcttaaatgtttttcggcactgggttgagcaccatttttat gactttgaaagagatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga gggaaagccatgaagaaatgggtagaatcaattgctaagatcatcaagaggaagaaacaa gctcaggcaaatggaataagccacaatattacctttgaaagtccacctccaccaattgaa tggcatatcagcagaccaggacagtttgaaacatttgatctcatgacacttcatccaata gaaattgcacgtcaactgacacttttggaatctgatctttacaggaaagtacaaccttct gaacttgtaggaagtgtatggaccaaagaagataaagaaataaattctccaaatttatta aaaatgattcgccacactacaaatcttacgctctggtttgaaaagtgcattgtggaagca gaaaattttgaggaacgagtggcagtactgagtagaattatagaaattctgcaagttttt caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca gtatacagactagaccatacctttgaggcattgcaggaaagaaaaaggagaattttggat gaagctgtggaattgagtcaagaccactttaaaaaatacctagtaaaacttaagtcaatc aatccaccctgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa gggaataatgattttttaaaaaagaaagggaaagacttaatcaatttcagtaagaggagg aaagtggctgaaattactggagaaattcagcagtatcagaatcaaccttattgtttacgg atagaaccagaaatgaggcgattctttgaaaatcttaaccccatgggaagtgcttctgaa aaagagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa cagccacctcgatttcctaggaaatcaactttctctttgaaatctcctggaataaggcct aatacaggccgacatggctctacctcaggcactttacgaggtcatccaacaccattggaa agagaaccatgtaaaataagctttagtcggattgctgaaactgagcttgagtcaacagtg tcagcaccaacctctccaaacacaccatctactccgccagtatctgcttcttcagacctc agtgtgtttttagatgtggatctcaatagttcctgtggcagcaatagcatctttgctcca gttctcttgccacattcaaagtctttcttcagttcgtgtggtagtttacataaacttagt gaagagccactgattcctcctccacttcctcctcgaaaaaagtttgatcatgatgcttca aattccaagggaaatatgaaatctgatgatgacccccctgctattccaccgagacaacct cctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgatgggcctctg catagtccacctccaccgccaccgagagatcctcttcctgatacccctccaccggttccc cttcggcctccagaacactttataaactgtccatttaatcttcagccacctccgctggga catcttcacaaagatccagactggttcagagatgttagtacgtgtcctaattcgccaaac actcctcctagcacaccctctccaagggtgccacgtcgatgctatgtgctcaattctagt cagaataatcttgctcatcctcaagctccccctgttccaccacggcagacttcaagccct cacctcccaaaactgccaccaaagacttacaaacgggagctttcacatcccccattgtac agactgcctttgctagaaaatgcagaaactcctcaatga

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