Pteropus vampyrus (Indian flying fox): 120610872
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Entry
120610872 CDS
T07511
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig04217
Necroptosis
pgig04380
Osteoclast differentiation
pgig04620
Toll-like receptor signaling pathway
pgig04621
NOD-like receptor signaling pathway
pgig04630
JAK-STAT signaling pathway
pgig04658
Th1 and Th2 cell differentiation
pgig04659
Th17 cell differentiation
pgig05145
Toxoplasmosis
pgig05160
Hepatitis C
pgig05161
Hepatitis B
pgig05162
Measles
pgig05164
Influenza A
pgig05165
Human papillomavirus infection
pgig05167
Kaposi sarcoma-associated herpesvirus infection
pgig05168
Herpes simplex virus 1 infection
pgig05169
Epstein-Barr virus infection
pgig05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
120610872 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
120610872 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
120610872 (TYK2)
04621 NOD-like receptor signaling pathway
120610872 (TYK2)
04658 Th1 and Th2 cell differentiation
120610872 (TYK2)
04659 Th17 cell differentiation
120610872 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
120610872 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
120610872 (TYK2)
05160 Hepatitis C
120610872 (TYK2)
05171 Coronavirus disease - COVID-19
120610872 (TYK2)
05164 Influenza A
120610872 (TYK2)
05162 Measles
120610872 (TYK2)
05168 Herpes simplex virus 1 infection
120610872 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
120610872 (TYK2)
05169 Epstein-Barr virus infection
120610872 (TYK2)
05165 Human papillomavirus infection
120610872 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
120610872 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pgig01001
]
120610872 (TYK2)
Enzymes [BR:
pgig01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
120610872 (TYK2)
Protein kinases [BR:
pgig01001
]
Non-receptor tyrosine kinases
JAK family [OT]
120610872 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
FERM_C_FAK1
Kdo
ABC1
RA_2
Motif
Other DBs
NCBI-GeneID:
120610872
NCBI-ProteinID:
XP_039729159
LinkDB
All DBs
Position
Unknown
AA seq
1183 aa
AA seq
DB search
MPLYHWGATARDSRPDGDGTQLTATRGGLKVFLHWAGPDGREPWVTFSEATLTAEDVCMH
IAHKVGITPPCFSLFALFDAQAQVWLPPNHILEVSRDTSLTLHFRMRFYFRNWHGTNPQE
PAVYRCRPPGAKASSEQAEQGMRLLDPASFEYLFEQGKHEFVNDVASLWDLSNEEEIHHF
KNESLGMAFLHLCHLSVCLGVPLKKVARKISFKDCIPRSFRQQIQQHNAFTQLRLWIIFH
KFLWAFQPGHLSQQVIMVKYLATLERLAPRFGSERVPVCHLELLAQAKGKPCYVEDSSQA
PPDPGPESAPGPPTHEVLVTGTGGIRWRPAQAEGPSGGDGGRRRNPHAGSSGKKMKAQES
VTQPVDRLQEAPWTYFCDFQDITHVVLRECHVSIHCQDKCLKLTLPSRAVALSLVSLVDG
YFRLTADSNHYLCHEVAPPRLVMSIQDGVHGPLLEPFVLAKLRPEDGLYLIHWSTSHFNR
LILTVAQKDQAPGGQCLRLRKFPIELHAGTFTLESWDRSFPSVRELRAALQGYLLRAGDD
CFSLRHCCLPQPGEISNLIIRWGPEASTKPLGLSQLSFHRVCQDDITQLSHLGQGTRTNV
YEGLLRVGDRGPEEDKADGGDSPTAGRGHGQELRVVLKVLDPSHHGIALAFYETASLMSQ
VSHMHLAFVHGVCVHGSKNIMVAEYVEHGPLDVWLRRERGCVPVAWKVVVAQQLASALSY
LEDKSLAHGNVCGRNILLARPGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLPPECL
SGGANSLSTAADKWGFGATLLEICFNGEAPLQGRSPSEKEHFYQKQYQLPEPSCLELAML
TSQCLTYEPAQRPSFRTILRDLTRLQPQNLDDGLAVNPDCQASDPTVFHKRYLKKIRDLG
EGHFGKVSLYCYDPTNDSTGEMVAVKALKAGSGPQLSTGWRREIDILRTLSHENIVKYKG
CCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHTQHYIHRDL
AARNVLLDNNRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDV
WSFGVTMYELLTYCDSSQSPPSKFIELIGFTQGQMTVLRLTELLERGERLPRPEKCPCEI
YLLMKKCWKAEASFRPTFQNLIPILKTAHEKYQGQAPSVFSVC
NT seq
3552 nt
NT seq
+upstream
nt +downstream
nt
atgcctttgtatcactggggggccacagccagggacagcaggcctgatggggacggaacc
cagctcacggccaccagaggaggcctgaaggtattcctgcactgggctggccccgatggt
agagagccctgggtcaccttcagcgaggccacactgactgcagaggacgtctgcatgcac
attgcacacaaagtcggcatcactccaccctgcttcagtctctttgccctcttcgatgcc
caggcccaggtctggctgcccccaaaccacattctagaggtctccagagatacaagcctg
acgctgcacttccgcatgagattttatttccggaactggcatggcacaaatcctcaggag
ccagctgtgtaccgctgcaggcccccaggggccaaggcttcatcagaacaggcagagcag
ggcatgcgactcctggacccagcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgacgtagcatcgctgtgggacctgtcgaacgaggaggagatccaccacttt
aagaatgagagcctgggcatggcctttctgcacctctgccacctctctgtctgccttggt
gttcccctaaagaaggtggccagaaagatcagcttcaaagactgcatcccacgctccttc
cggcaacagatccagcaacacaacgcgttcacacaactgcgcctgtggatcatcttccac
aagttcctgtgggccttccagccaggccacctctcccaacaggtcatcatggtcaagtac
ctggccacactcgagcggctggcgccccgctttggctcggagcgcgtgcctgtgtgccac
ctagagctgctggcccaggccaaggggaagccgtgctacgtcgaggatagcagtcaggcc
cctccggaccctgggcccgagtctgctccaggaccccctacccatgaggtgctggtgact
ggcactggtggcatccggtggcggccagcacaggcagagggtcccagtggtggtgatggt
ggcaggagaaggaatccccatgccggctcatctgggaagaaaatgaaggcccaagagtca
gtcacccaacctgtggacaggctgcaggaggcgccatggacctacttctgtgacttccag
gacatcacccacgtagtactgagagaatgccatgtcagcatccactgtcaggacaagtgc
ctgaagctgactctgccttcccgggccgtggccctgtccttggtatcactggtggatggc
tatttccgcctgacggccgactcaaaccactacctatgccatgaagtggctcctccacgg
ctggtgatgagtatccaggatggtgtccacggacccctgctggagccattcgtgctggcc
aagctgcgaccagaggatggcctctatctcatccactggagcaccagccacttcaaccgc
ctcatccttacggtggcccagaaagaccaggcacctggcggacagtgcttgcgcctgcgg
aagttccccattgagctgcatgcagggacctttacgctggagagctgggacaggtccttc
cccagtgtgcgtgagcttcgggctgccctgcagggctacttgctgcgggccggtgatgac
tgcttctccctgcgccactgctgcctgccacagccaggagagatctccaacctcatcatc
aggtgggggcctgaggccagcaccaagcctctcggcctcagccagctcagcttccaccgg
gtctgccaggatgacatcacccagctgtcccacttaggccagggcacaaggaccaatgtg
tatgagggcctcctgagagtgggtgacagaggacctgaggaagacaaggcagatggtggg
gattcccccacagcaggcaggggccatgggcaggagctgcgagtggtgctgaaggtgctg
gaccccagccaccatggcatcgccctggccttctacgagacagccagcctcatgagccag
gtatcccacatgcacctggccttcgtccatggcgtctgcgtgcatggctccaagaacatc
atggtggcagagtacgtggaacatggacccctagatgtgtggctgcggcgggagaggggc
tgcgtgcctgtggcctggaaggtggtggtggcccagcagctggccagtgccctcagttac
ctggaagacaagagcctggcgcatggtaatgtgtgtggccggaacatcctgctggcacgt
ccagggttggcggagggcaccagcccattcatcaagctgagcgaccccggcgtgggcctg
ggtgccctctccagggaggaacgggtagagcggatcccctggctgcccccggagtgcctg
tctggtggggccaacagcctcagcacagcagctgacaagtggggttttggcgccaccctc
ctggagatctgcttcaacggggaggctcccctgcaaggccgcagcccctccgagaaagag
cacttctaccagaagcagtaccagctgcctgaaccctcgtgcctggagctggccatgctt
accagccagtgcctgacctatgagccagcccaacggccgtccttccgcaccatcctgcgt
gacctcactcggctgcagcctcaaaatcttgatgatggcttggctgtgaatccagactgt
caggcgtcagaccccactgttttccacaagcgctatttgaaaaagatccgggatctgggc
gagggtcactttggcaaagtcagcctgtactgctacgacccgaccaatgacagcactggc
gagatggtggccgtgaaggcccttaaggcgggctccggcccccagctcagcaccggctgg
aggcgggagatcgacatcctgcgcacgctctctcacgagaacatcgtcaaatacaagggc
tgctgcgaggaccaaggcgagaaatcagtgcagctcgtcatggagtacgtgcccctgggc
agcctccgagactacctgccccggcacagcgttggcctggcccagctgctgctgtttgct
cagcagatctgcgagggcatggcctacctgcacacgcagcactacatccaccgagacctg
gctgcgcgcaacgtgctgctggacaacaataggctggtcaagattggcgattttggccta
gccaaagctgtgcctgaaggccacgagtactaccgcgtgcgagaggatggggacagtcct
gtgttctggtatgccccagagtgcctgaaggagtgtaagttctactatgcatctgacgtc
tggtcctttggggtcaccatgtatgaactgctgacctactgtgactccagccaaagcccc
ccttcgaaatttatcgagcttataggcttcacccaggggcagatgacagtactgaggctc
acagagctgctggagcgaggagagaggctgccgcggccagagaaatgtccctgtgagatc
tatctcctcatgaagaagtgctggaaggcagaggcctcattccgcccaaccttccagaac
ctcatacccatcctgaaaacagcccacgagaaatatcagggccaggccccctcggtgttc
agtgtctgctga
DBGET
integrated database retrieval system
