KEGG   Pteropus vampyrus (Indian flying fox): 120620377
Entry
120620377         CDS       T07511                                 
Symbol
GRIN2A
Name
(RefSeq) glutamate receptor ionotropic, NMDA 2A
  KO
K05209  glutamate receptor ionotropic, NMDA 2A
Organism
pgig  Pteropus vampyrus (Indian flying fox)
Pathway
pgig04014  Ras signaling pathway
pgig04015  Rap1 signaling pathway
pgig04020  Calcium signaling pathway
pgig04024  cAMP signaling pathway
pgig04080  Neuroactive ligand-receptor interaction
pgig04082  Neuroactive ligand signaling
pgig04713  Circadian entrainment
pgig04720  Long-term potentiation
pgig04724  Glutamatergic synapse
pgig04728  Dopaminergic synapse
pgig05010  Alzheimer disease
pgig05014  Amyotrophic lateral sclerosis
pgig05017  Spinocerebellar ataxia
pgig05020  Prion disease
pgig05022  Pathways of neurodegeneration - multiple diseases
pgig05030  Cocaine addiction
pgig05031  Amphetamine addiction
pgig05033  Nicotine addiction
pgig05034  Alcoholism
pgig05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:pgig00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    120620377 (GRIN2A)
   04015 Rap1 signaling pathway
    120620377 (GRIN2A)
   04020 Calcium signaling pathway
    120620377 (GRIN2A)
   04024 cAMP signaling pathway
    120620377 (GRIN2A)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    120620377 (GRIN2A)
   04082 Neuroactive ligand signaling
    120620377 (GRIN2A)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    120620377 (GRIN2A)
   04728 Dopaminergic synapse
    120620377 (GRIN2A)
   04720 Long-term potentiation
    120620377 (GRIN2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    120620377 (GRIN2A)
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    120620377 (GRIN2A)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    120620377 (GRIN2A)
   05014 Amyotrophic lateral sclerosis
    120620377 (GRIN2A)
   05017 Spinocerebellar ataxia
    120620377 (GRIN2A)
   05020 Prion disease
    120620377 (GRIN2A)
   05022 Pathways of neurodegeneration - multiple diseases
    120620377 (GRIN2A)
  09165 Substance dependence
   05030 Cocaine addiction
    120620377 (GRIN2A)
   05031 Amphetamine addiction
    120620377 (GRIN2A)
   05033 Nicotine addiction
    120620377 (GRIN2A)
   05034 Alcoholism
    120620377 (GRIN2A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:pgig04040]
    120620377 (GRIN2A)
Ion channels [BR:pgig04040]
 Ligand-gated channels
  Glutamate (ionotropic)
   120620377 (GRIN2A)
SSDB
Motif
Pfam: NMDAR2_C Lig_chan Lig_chan-Glu_bd ANF_receptor SBP_bac_3
Other DBs
NCBI-GeneID: 120620377
NCBI-ProteinID: XP_039741251
LinkDB
Position
Unknown
AA seq 1456 aa
MGRLGYWTLLVLPALLIWRGPAQGAAAEKGPPALNIAVLLGHSHDVTERELRNLWGPEQA
AGLALDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSQT
FVPILGIHGGSSMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGY
RDFISFIKTTVDNSFVGWDMQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLIL
SEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGLGILT
TAASSMLERFSYIPEAKASCYGQAEKPEIPLHTLHQFMVNVTWDGKDLSFTEEGYQVHPR
LVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVE
DIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLV
TNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRS
NGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFT
IGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVD
QVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSL
KTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALL
QFVGDGEMEELETLWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFVWEHL
FYWKLRFCFTGVCSDRPGLLFSISRGIYSCIHGVHIEEKKKSPDFNLTGSQSNMLKLLRS
AKNISGLSNMNSSRMDSPKRAADLIQRGSLIMDMVSDKGNLIYSDNRSFQGKDSIFGDNM
NELQTFVANRHKDNLNNYVFQGQHPLTLNESNPNTVEVAVSTEAKGSSRPRQLWKKSMDS
LRQDSVTQNPVSQRDEGTAENRTHSLKSPRYLPEEVAHSDISETSNRAACHREPNNNKNH
KTKDNFKRSVASKYPKDCGEVERSYLKSKASPQGTLHQRRRSRPPDPSSGNTLPENVDFP
DAYQDRGESFRQGDPTLPMNRNPPHKEDGLPNNNQYKLYSKHFTLKDKSSPLSEGSDRYR
QNSTHCRSCLSNLPTYAGHFTVRSPFKCDACLRMGNLYDIDEDQMLQETGNPATQEEVYQ
QDWAQNNTLQFQKNKLRISRQHSYDNILDKPRELDLSRPSRSISLKDRERLLEGNLYGSL
VSVPSSKLLGNKSSLFPRGLEDTRRSKSLLPDHASDNPFLHPCADDQRLVIGRCPSDPYK
HSLPSQTASDSYLRSSLRSTASYCSRDSRGHSDVYISEHVMPYAANKNHMYSAPRVLNSC
SNRRVYKKMPSIESDV
NT seq 4371 nt   +upstreamnt  +downstreamnt
atgggcagactgggctattggaccctgctggtgctgccggcacttctcatctggcgcggt
ccggcgcagggcgcggcggcggagaagggtcccccggcactgaacatcgcggtgctgctg
ggccacagccacgacgtgacggagcgcgaactgcgaaacctgtggggcccagagcaagca
gcagggctggccctggacgtgaatgtggtagcgctgttaatgaaccgcaccgaccccaag
agcctcatcacacatgtgtgcgacctcatgtccggggcacgcatccacggcctagtgttt
ggggacgacaccgaccaagaggccgtggcccagatgctggattttatctcctcacagact
tttgtccccatcctgggcatccatgggggctcatctatgatcatggctgacaaggacccg
acgtctaccttcttccagtttggcgcatccatccaacaacaagccacggtcatgctgaag
atcatgcaggattatgactggcacgtcttctccctggtgaccaccatcttccctggctac
agagacttcatcagcttcatcaagaccacagtggacaatagctttgtgggttgggacatg
cagaacgtgatcaccctggacacttctttcgaggatgccaagactcaagtccagttgaaa
aagatccattcttctgtcatcttgctctactgttccaaagatgaggccgtcctcatcctg
agtgaggcccgctcccttggcctcaccgggtatgacttcttctggattgtcccaagcctg
gtctctgggaacacggagctcatccccaaagagtttccgtcaggactcatttcagtctct
tacgacgactgggactacagcctggaggcacgagtaagggacggcctgggcatcctaacc
actgctgcgtcttccatgttggagaggttctcctacatccctgaagccaaggccagctgc
tacgggcaggcggagaagccagagatcccgctgcacacgctgcaccaatttatggtcaat
gtgacatgggatggcaaagacctgtccttcactgaggaaggctatcaagtacaccccagg
ctggtggtgatcgtgctgaacaaggaccgagaatgggaaaaggtgggcaagtgggaaaac
cacaccctgagcctgaggcacgctgtgtggccaaggtacaagtccttttcagactgtgag
ccagacgacaaccacctgagcatcgtcaccctggaggaggcgccctttgtcatcgtggag
gacatagacccgctgaccgagacatgtgtaaggaacactgtaccgtgtcggaagttcgtc
aaaatcaataattcaaccaatgagggaatgaatgtaaaaaaatgctgcaagggcttctgc
atcgatatcctaaagaagctttccagaaccgtcaagtttacctatgacctttacctggtg
acgaacgggaagcacggcaaaaaagttaacaacgtgtggaatggaatgattggcgaagtc
gtctatcagcgggcggtcatggcagttggctcactcaccatcaatgaggaacgttccgaa
gtggtggacttctccgtgcccttcgtggagacgggaatcagtgtcatggtttcgagaagc
aacggcaccgtctcaccttctgcttttctagaaccattcagtgcctccgtctgggtgatg
atgtttgtgatgctgctcattgtttccgccatagctgttttcgtctttgaatacttcagt
cctgtgggatacaacagaaacttagccaaagggaaagcaccccacgggccttcttttacc
attggaaaagctatatggctcctttggggcctggtgttcaacaactctgtgcctgtccag
aaccctaaaggcaccaccagcaagatcatggtgtccgtgtgggccttctttgctgtcata
ttcctggccagctacacggccaatctggcggctttcatgatccaggaggaatttgtggac
caagtgaccggcctcagtgacaaaaagtttcagagaccccacgactattccccacctttt
cgattcggcacggtgcctaacggcagcaccgaaagaaacatccggaataactacccctac
atgcatcagtacatgaccaaatttaatcagaagggagtggaggacgccttggtcagcttg
aaaacagggaagctggacgcgttcatctacgatgcggcggtcttgaattacaaggctggg
cgggacgaaggctgcaagctggtgaccattgggagtggatacatctttgccaccactggt
tacggaattgccctccagaaaggctccccttggaagaggcagattgacttggccctgctt
cagtttgtgggcgatggtgagatggaggagctggagaccctgtggctcactggcatctgc
cacaacgagaagaatgaggtgatgagcagtcagctggacatcgacaacatggcgggtgtc
ttctacatgctggcggccgccatggccctgagcctcatcaccttcgtttgggagcacctc
ttctactggaagctgcgcttctgtttcacgggcgtgtgctccgatcgacccgggctgctc
ttctccatcagcaggggtatttacagctgcattcacggggtacacatcgaggaaaagaag
aagtcaccagacttcaatctgaccgggtcgcagagcaacatgttgaagctccttcggtca
gccaagaacatctccggcctgtccaacatgaactcctcaagaatggattcccccaaaaga
gctgccgacctcatccaaagaggttccctcatcatggacatggtttcggataaggggaac
ctgatatattcagacaacaggtcctttcaggggaaagacagcatttttggggacaacatg
aacgagctccagacgttcgtggccaacaggcacaaggacaacctcaacaactatgtgttc
cagggtcagcaccctctgaccctcaacgagtccaaccccaacacggtggaggtggccgtg
agcacggaggccaaagggagctcccggcctcggcagctttggaagaagtccatggactcg
ctacgccaagattcggtgacccagaaccccgtctcccagagggacgaaggtacagcggag
aacaggacccactccctgaagagtcccaggtaccttccagaagaggtggcccactcggac
atttcggaaacttcgaatcgggccgcgtgccacagggaacccaacaacaacaagaaccac
aagaccaaggacaatttcaaaaggtcggtggcctccaagtaccccaaggactgcggcgag
gtcgagcgctcctacctgaagagcaaagccagcccccaggggacactacaccagcgcaga
aggagccggccacctgaccccagttctggaaacacccttccggagaacgtggacttccca
gacgcctaccaggaccgtggcgagagcttccgccagggggaccccacgctgcccatgaac
aggaaccccccgcacaaggaggacgggcttcccaacaacaaccagtataaactctactcc
aagcacttcaccttgaaggacaagagctccccgctgagcgagggcagcgaccggtaccgg
cagaactccacgcactgcaggagctgcctgtccaacctgcccacctacgcaggccatttc
accgtgcggtcccccttcaagtgcgacgcctgcctacggatggggaacctctacgacatc
gacgaagaccagatgcttcaggagacaggtaatccagccacccaggaggaggtctaccag
caggactgggcacagaacaacaccctccagttccaaaagaacaagctccgaatcagccgt
cagcattcctatgataacattctcgacaaacctagggagctggaccttagcaggccctct
cggagcataagcctcaaggatagggagcggcttctggagggaaatttgtacgggagcctg
gttagcgtcccctccagcaaactgctggggaacaaaagctccctcttcccccggggtctg
gaggacactaggcggagcaagtctctcttgccagaccacgcctccgacaaccctttcctc
cacccctgtgcggacgaccagcgcttagtcattgggaggtgcccctcggacccttataaa
cactcactgccatcccagacagcgagtgacagctaccttcgatcgtccttgaggtcaacg
gcttcgtactgttccagggacagtagaggccacagcgatgtgtatatttctgagcatgtt
atgccttatgctgcaaataagaatcatatgtactctgcccccagggttttgaattcctgc
agcaatagacgcgtgtacaagaaaatgcctagtatcgaatccgatgtttaa

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