Pteropus vampyrus (Indian flying fox): 120621751
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Entry
120621751 CDS
T07511
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig01521
EGFR tyrosine kinase inhibitor resistance
pgig01522
Endocrine resistance
pgig04010
MAPK signaling pathway
pgig04012
ErbB signaling pathway
pgig04014
Ras signaling pathway
pgig04062
Chemokine signaling pathway
pgig04068
FoxO signaling pathway
pgig04072
Phospholipase D signaling pathway
pgig04150
mTOR signaling pathway
pgig04151
PI3K-Akt signaling pathway
pgig04510
Focal adhesion
pgig04540
Gap junction
pgig04630
JAK-STAT signaling pathway
pgig04650
Natural killer cell mediated cytotoxicity
pgig04660
T cell receptor signaling pathway
pgig04662
B cell receptor signaling pathway
pgig04664
Fc epsilon RI signaling pathway
pgig04714
Thermogenesis
pgig04722
Neurotrophin signaling pathway
pgig04810
Regulation of actin cytoskeleton
pgig04910
Insulin signaling pathway
pgig04912
GnRH signaling pathway
pgig04915
Estrogen signaling pathway
pgig04917
Prolactin signaling pathway
pgig04926
Relaxin signaling pathway
pgig04935
Growth hormone synthesis, secretion and action
pgig05034
Alcoholism
pgig05160
Hepatitis C
pgig05161
Hepatitis B
pgig05163
Human cytomegalovirus infection
pgig05165
Human papillomavirus infection
pgig05200
Pathways in cancer
pgig05205
Proteoglycans in cancer
pgig05206
MicroRNAs in cancer
pgig05207
Chemical carcinogenesis - receptor activation
pgig05208
Chemical carcinogenesis - reactive oxygen species
pgig05210
Colorectal cancer
pgig05211
Renal cell carcinoma
pgig05213
Endometrial cancer
pgig05214
Glioma
pgig05215
Prostate cancer
pgig05220
Chronic myeloid leukemia
pgig05221
Acute myeloid leukemia
pgig05223
Non-small cell lung cancer
pgig05224
Breast cancer
pgig05225
Hepatocellular carcinoma
pgig05226
Gastric cancer
pgig05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
120621751 (SOS1)
04012 ErbB signaling pathway
120621751 (SOS1)
04014 Ras signaling pathway
120621751 (SOS1)
04630 JAK-STAT signaling pathway
120621751 (SOS1)
04068 FoxO signaling pathway
120621751 (SOS1)
04072 Phospholipase D signaling pathway
120621751 (SOS1)
04151 PI3K-Akt signaling pathway
120621751 (SOS1)
04150 mTOR signaling pathway
120621751 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
120621751 (SOS1)
04540 Gap junction
120621751 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
120621751 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
120621751 (SOS1)
04660 T cell receptor signaling pathway
120621751 (SOS1)
04662 B cell receptor signaling pathway
120621751 (SOS1)
04664 Fc epsilon RI signaling pathway
120621751 (SOS1)
04062 Chemokine signaling pathway
120621751 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
120621751 (SOS1)
04912 GnRH signaling pathway
120621751 (SOS1)
04915 Estrogen signaling pathway
120621751 (SOS1)
04917 Prolactin signaling pathway
120621751 (SOS1)
04926 Relaxin signaling pathway
120621751 (SOS1)
04935 Growth hormone synthesis, secretion and action
120621751 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
120621751 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
120621751 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120621751 (SOS1)
05206 MicroRNAs in cancer
120621751 (SOS1)
05205 Proteoglycans in cancer
120621751 (SOS1)
05207 Chemical carcinogenesis - receptor activation
120621751 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
120621751 (SOS1)
05231 Choline metabolism in cancer
120621751 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
120621751 (SOS1)
05225 Hepatocellular carcinoma
120621751 (SOS1)
05226 Gastric cancer
120621751 (SOS1)
05214 Glioma
120621751 (SOS1)
05221 Acute myeloid leukemia
120621751 (SOS1)
05220 Chronic myeloid leukemia
120621751 (SOS1)
05211 Renal cell carcinoma
120621751 (SOS1)
05215 Prostate cancer
120621751 (SOS1)
05213 Endometrial cancer
120621751 (SOS1)
05224 Breast cancer
120621751 (SOS1)
05223 Non-small cell lung cancer
120621751 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
120621751 (SOS1)
05160 Hepatitis C
120621751 (SOS1)
05163 Human cytomegalovirus infection
120621751 (SOS1)
05165 Human papillomavirus infection
120621751 (SOS1)
09165 Substance dependence
05034 Alcoholism
120621751 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
120621751 (SOS1)
01522 Endocrine resistance
120621751 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
120621751
NCBI-ProteinID:
XP_039743294
UniProt:
A0A6P3Q5Y2
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITEQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKSFMAEIRQYIRELNLIIKVFREPFVSNSKLFSTN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPLHSSSDTVFTQLTLSHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSVSDAPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctagtgcctgcgctgaaaaaggtccagggacaagttcatcctactcttgagtct
agtgatgatgctcttcaatatgttgaagaattaatcttgcaactattaaatatgctatgc
caagctcagccccgaagtgcttccgatgtagaggaacgagttcaaaaaagttttcctcat
ccaattgataagtgggcaatagctgatgcccaatcggctattgaaaagaggaaacgaaga
aatcctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtacgaaatatacggcattatgaaattacagaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tactatgatttggtaaaatcatttatggcagaaattcgacaatacataagggaactaaat
ttaattataaaagtttttagagagccttttgtctccaattcaaaattgttttcaactaac
gatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgactgatgaaggcagtccccatccattagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggttttcacgatcattttcttagtcagttatcaaagcctggagca
gcactttatttacagtcaataggcgaaggtttcaaggaagctgttcaatatgttttaccc
aggctgcttctagccccggtttaccactgtctacattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcaaagtggtatggaaaaaatatgttcaaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaatgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagtaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccgaagtacactggaaaggatgcttgatgtgacaatgctacag
gaagagaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagcct
gactctgaagagaacataatatttgaagaaaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaactgatagagaggctcacataccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
attgctatagagaatggagatcaacccttgagtgcagaactaaaaagatttagaaaagaa
tatatacagcctgtacaactgcgcgtattaaatgtatgtcggcactgggttgagcatcac
ttctatgattttgaaagagatgcagatcttttgcagcgaatggaggaatttattgggaca
gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccgatagaaattgctcgacaactcactttacttgaatcagatctatatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcacaccactaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaataattgaaattctgcaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactca
tcacctgtttacaggctagaccacacgtttgagcaaataccaagtcgtcaaaagaaaatt
ttagaagaagctcacgaattaagcgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggttctaaaaaggcatggaaaagagcttataaactttagtaaa
aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtggaatcagatatcaaaaggttctttgaaaacttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccttaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
aggaaaattagttacagtcggatccctgaaagtgagacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttctagtaccacagat
gtttgcagcgtatttgattctgatcattcgagccctcttcactcaagcagcgataccgtc
tttacccaacttacactgtcccatggcccaagatctgcttcagtatcatctataagttta
accaagggcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcgtcgccatctaagattatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcttattcaccacgatactcaatatcagac
cggacttctgtatcagacgctcctgaaagccctcccttgttaccaccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgatcatggcaatgccttcttcccaaacagcccttcccccttcacgccacctcct
cctcaaacaccttctcctcatggcacgagaaggcatctgccatcaccaccgttgacacaa
gaagtggaccttcattccattgctgggccacctgttcctccacgacaaagcacttctcaa
catattcctaaactccctccaaaaacttacaaaagggagcacacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga
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integrated database retrieval system
