Pteropus giganteus (Indian flying fox): 120622031
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Entry
120622031 CDS
T07511
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
pgig
Pteropus giganteus (Indian flying fox)
Pathway
pgig05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
120622031 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pgig01002
]
120622031 (BACE1)
Enzymes [BR:
pgig01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
120622031 (BACE1)
Peptidases and inhibitors [BR:
pgig01002
]
Aspartic peptidases
Family A1: pepsin family
120622031 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
Motif
Other DBs
NCBI-GeneID:
120622031
NCBI-ProteinID:
XP_039743932
LinkDB
All DBs
Position
Unknown
AA seq
531 aa
AA seq
DB search
MGTKPGVGSWEGGPKQGQRAGVTVKRCLWRLREAKKPEQALGEVQSAVPQRTTGARRSQQ
RGGNWSPEKHGDLPMVTMSEPGPKLMSADFTALRRKDTEKKSPELRGEAELNILVDTGSS
NFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVR
ANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCG
AGFPLNQSEALASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMD
CKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTP
WNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAV
IMEGFYVVFDRARKRIGFAVSACHGESATVWVHDEFRTAAVEGPFVTPDMEDCGYNIPQT
DESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRHQHDDFADDISLLK
NT seq
1596 nt
NT seq
+upstream
nt +downstream
nt
atgggaaccaagccaggagtggggagctgggaaggagggccaaagcagggtcagagagct
ggggtgacagtgaagaggtgtctttggagactgagggaggccaagaagcctgagcaggcc
ttgggggaggtgcagtcagcagtgccacagaggaccactggagcaagaaggagccagcag
agaggaggaaactggagcccagagaagcatggtgacctgcctatggtgacaatgtcagag
cctggacccaaattgatgtcagctgacttcactgcactgaggagaaaagatacagaaaag
aaaagccctgagctcaggggagaagctgagctcaacatcctggtggacacaggaagcagt
aactttgcagtgggggctgcccctcacccttttctgcatcgctactaccagagacagctg
tccagcacataccgggacctccggaagggcgtgtatgtaccctatacccaggggaagtgg
gagggggagctgggcaccgacctggtgagcatcccccatggccccaatgtcactgtgcgt
gccaacattgctgccatcactgaatcagacaagttcttcattaacggctccaactgggaa
ggcatcctggggctggcctatgctgagatcgccaggcccgatgactctctggagcctttc
tttgactccctggtaaagcagacccacgttcccaacctcttctccctgcagctctgtggt
gctggcttccccctcaaccagtcagaagcgctggcctcagttggagggagcatgatcatt
gggggtatcgaccactcactgtacacaggcagcctctggtacacacccatccggcgggag
tggtattatgaggtgatcattgtgcgggtagagatcaatggacaggatctgaaaatggac
tgcaaggagtacaactatgacaagagcatcgtggacagtggcaccaccaaccttcgtttg
cccaagaaagtttttgaagctgcagtcaaatccatcaaggcagcctcctcgacggagaag
tttccagacggcttttggctaggggaacagttggtatgctggcaagcagggactacccct
tggaacattttccccgtcatctcactctacctaatgggtgaagtgaccaatcagtccttc
cgcatcaccatccttccacagcaatacctgcggccagtggaagacgtggccacgtctcaa
gacgactgttacaagtttgccatctcacagtcatccaccggcactgttatgggagctgtt
atcatggagggcttctatgtcgtctttgatcgggcccgaaaacgaattggctttgctgtc
agtgcctgccatggtgagagcgccacagtgtgggtacacgatgagttcaggacggcagcg
gtggaaggcccttttgtcaccccagacatggaagactgtggctacaacattcctcagaca
gatgaatcaacactcatgaccattgcctatgtcatggctgccatttgcgccctcttcatg
ctgccactctgcctcatggtgtgtcagtggcgctgtctccgctgtctacgccatcaacat
gatgactttgctgatgacatctccctgctgaagtga
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