Pteropus vampyrus (Indian flying fox): 120622970
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Entry
120622970 CDS
T07511
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
pgig
Pteropus vampyrus (Indian flying fox)
Pathway
pgig00562
Inositol phosphate metabolism
pgig01100
Metabolic pathways
pgig01521
EGFR tyrosine kinase inhibitor resistance
pgig04012
ErbB signaling pathway
pgig04014
Ras signaling pathway
pgig04020
Calcium signaling pathway
pgig04062
Chemokine signaling pathway
pgig04064
NF-kappa B signaling pathway
pgig04066
HIF-1 signaling pathway
pgig04070
Phosphatidylinositol signaling system
pgig04072
Phospholipase D signaling pathway
pgig04360
Axon guidance
pgig04370
VEGF signaling pathway
pgig04380
Osteoclast differentiation
pgig04611
Platelet activation
pgig04613
Neutrophil extracellular trap formation
pgig04625
C-type lectin receptor signaling pathway
pgig04650
Natural killer cell mediated cytotoxicity
pgig04662
B cell receptor signaling pathway
pgig04664
Fc epsilon RI signaling pathway
pgig04666
Fc gamma R-mediated phagocytosis
pgig04670
Leukocyte transendothelial migration
pgig04722
Neurotrophin signaling pathway
pgig04750
Inflammatory mediator regulation of TRP channels
pgig04919
Thyroid hormone signaling pathway
pgig04933
AGE-RAGE signaling pathway in diabetic complications
pgig04935
Growth hormone synthesis, secretion and action
pgig05167
Kaposi sarcoma-associated herpesvirus infection
pgig05169
Epstein-Barr virus infection
pgig05170
Human immunodeficiency virus 1 infection
pgig05171
Coronavirus disease - COVID-19
pgig05200
Pathways in cancer
pgig05205
Proteoglycans in cancer
pgig05206
MicroRNAs in cancer
pgig05214
Glioma
pgig05223
Non-small cell lung cancer
pgig05225
Hepatocellular carcinoma
Module
pgig_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pgig00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
120622970 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
120622970 (PLCG2)
04014 Ras signaling pathway
120622970 (PLCG2)
04370 VEGF signaling pathway
120622970 (PLCG2)
04064 NF-kappa B signaling pathway
120622970 (PLCG2)
04066 HIF-1 signaling pathway
120622970 (PLCG2)
04020 Calcium signaling pathway
120622970 (PLCG2)
04070 Phosphatidylinositol signaling system
120622970 (PLCG2)
04072 Phospholipase D signaling pathway
120622970 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
120622970 (PLCG2)
04613 Neutrophil extracellular trap formation
120622970 (PLCG2)
04625 C-type lectin receptor signaling pathway
120622970 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
120622970 (PLCG2)
04662 B cell receptor signaling pathway
120622970 (PLCG2)
04664 Fc epsilon RI signaling pathway
120622970 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
120622970 (PLCG2)
04670 Leukocyte transendothelial migration
120622970 (PLCG2)
04062 Chemokine signaling pathway
120622970 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
120622970 (PLCG2)
04919 Thyroid hormone signaling pathway
120622970 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
120622970 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
120622970 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
120622970 (PLCG2)
04380 Osteoclast differentiation
120622970 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
120622970 (PLCG2)
05206 MicroRNAs in cancer
120622970 (PLCG2)
05205 Proteoglycans in cancer
120622970 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
120622970 (PLCG2)
05214 Glioma
120622970 (PLCG2)
05223 Non-small cell lung cancer
120622970 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
120622970 (PLCG2)
05171 Coronavirus disease - COVID-19
120622970 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
120622970 (PLCG2)
05169 Epstein-Barr virus infection
120622970 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
120622970 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
120622970 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pgig04131
]
120622970 (PLCG2)
Enzymes [BR:
pgig01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
120622970 (PLCG2)
Membrane trafficking [BR:
pgig04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
120622970 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
120622970 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
SH3_1
C2
PH
SH3_9
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
PH_14
Adhesin_E
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
120622970
NCBI-ProteinID:
XP_039744743
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MTTMVNVDTLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGSQFVLSTLSLAADSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPMVNFKVGSA
KFLKDKFVEIGAHKDELSFEQFHLLYKKLMFEQQKSIFDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDIQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCGVEQQRYMARV
FKEVFGDLLLIKPTEASADQLPSPTQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEELPQDTPPTELHFGEKWFHKKVEKR
ISAEKLLQEYCNETGGKDGTFLVRESERFPNDYTLSFWRSGRVQHCRIRSTMEGGIMKYY
LTDNLMFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRKREGTDSYAITFRAKGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMKLRYPVTPELLERYNMERDVNSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTVDVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDKVEELFEWF
HSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSVVRQKPIDLLKYNLKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccatggtcaacgtggacacccttccggaatacgagaagagccagatcaagagg
gccttggagctgggcacggtgatgactgtgttcagcttccgcaagtccaccccggagcgg
aggactgtccaggtgatcatggagacgcggcaagtggcctggagtaagacggctgacaaa
atcgagggcttcttggatatcatggaaataaaggaaatccgccccgggaagaactccaag
gatttcgagcgtgcaaaagcagtccgccagaaggaagactgctgtttcaccatcttgtat
ggcagccagttcgtcctcagcacactcagtttagcagctgactctaaggaagatgcaact
aagtggctctctggcttgaaaatcttacaccaagaagcgatgagcgcgtccacacccacc
attatcgagagttggctgagaaagcagatttattctgtggatcaaaccaggagaaatagc
atcagcctccgagagttgaaaaccatcttgcccatggtcaacttcaaagtaggcagtgcc
aagttcctcaaagataagtttgtggaaataggcgcacacaaagatgaactcagctttgaa
cagttccacctcctctataaaaagcttatgtttgaacaacaaaaatcgatttttgatgaa
ttcaaaaaagattcctccgtgttcatcttgggcaacaccgaccggccggatgcctccgct
gtccacttgcacgacttccagcggtttctcttacatgaacagcaggagcactgggctcag
gatctgaacaaagtccgtgagcggatgaccaaatttatcgatgacacgatgagggaaact
gccgagcccttcttgtttgtcgatgagttcctcacatacctgttttcacgggagaacagc
atttgggatgaaaagtatgacgtggtagacatacaggacatgaacaaccccttatcccat
tactggatctcctcatcacataacacgtacctcacaggtgaccagctgcggagtgagtca
tccacggaagcatacatccgctgtctgcgcatgggctgtcgctgcattgagctggactgc
tgggacgggcccgatgggaagcccatcatctaccatggctggacacggaccaccaagatc
aagtttgatgatgtcgtgcaggccatcaaagaccatgcctttgtcacctcaagcttccct
gtgatcctgtccatcgaggagcactgtggtgtggagcagcagcgctacatggccagagtg
ttcaaggaggtgtttggcgacttgctgctgataaagcccacggaggccagtgccgaccag
ctgccctcgcccacccagctgcgtgagaagatcatcatcaagcataagaagctgggcccc
cgaggtgatgtagatgtcaacatggaggacaagaaagatgagcacaagcaacagggtgaa
ctgtacatgtgggattccattgaccagaaatggactaggcactactgcgccattgctgat
gccaagttgtccttcagcgatgacattgaacagactgtggaagaggagctaccccaggat
acgccccccacggaactgcattttggagagaagtggttccataagaaggtggagaagagg
ataagtgccgagaagctgctgcaggaatactgcaatgagacggggggcaaggatgggacc
ttcctggtgcgggagagtgagaggttccccaacgactacaccttgtccttctggcggtct
ggccgggtccagcactgccggatccgctccaccatggagggtgggatcatgaagtactac
ctgactgacaacctcatgttcaccagcatctacgccctcatccagcactaccgtgagacg
cacctacggtgtgccgagttcgagctccggctcaccgaccccgtgcccaaccccaacccc
catgagtcaaagccgtggtactatgatgggctgagccgcggagaagcagaggacatgctg
atgagggttccccgggacggggccttcctcatccggaagcgagaaggtaccgactcgtac
gccatcaccttcagggccaagggcaaggtgaagcactgtcgcatcaaccgggatggccgg
cactttgtgctagggacctctgcctactttgagagcctggtggaactcgtcagttactac
gagaagcacgcgctctaccgaaagatgaaactgcgctaccccgtgacccccgagctcctg
gaacgctacaatatggaaagagatgtaaactccctgtatgacgtcagcagaatgtatgtg
gatcccagtgaaatcaatccttctatgcctcagagaaccgtgaaagctctgtatgactac
aaagccaagcagagtgatgagctgagcttttgccgtggtgctctcattcacaacgtctcc
aaggaacccgggggctggtggaaaggagactacggaaccagaatccagcagtacttcccg
tctaattacgtcgaggacatttcaacagtggatgtggaggagctggagaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatattggatctcaacacctataacgtt
gtgaaagccccacaagggaaaaaccagaagcctttcgtctttatcctggagcccaagaag
cagggtgaccctccggtggagtttgccacagacaaggtggaagagctctttgagtggttt
cacagcattcgggagatcacctggaagattgacaccaaggagaacaacatgaagtactgg
gagaagaaccagtcgattgccatcgagctctcggacctggtcgtctactgcaaaccaacc
agcaagaccaaggacaatttagaaaaccccgacttccgagaaatccgctcctttgtggag
acgaaggctgacagcgtcgtcagacagaaacccattgatctcctgaagtacaatctaaag
ggcctgacccgcgtttacccgaagggacagagggtggactcctccaactacgatcccttc
cgcctctggctgtgtggctcccaaatggtggcgctcaatttccagacagcagataaatac
atgcagatgaatcaggccttgttttcactcaatgggcggactggctacgtcctacagcct
gagagcatgaggacggagaagtatgaccccatgccgcctgagtcccagcggaagatcctg
atgaccttgacagtcaaggttctcggggctcgacatctccccaagcttggacgaagtatt
gcgtgtccctttgtggaggtggaaatatgtggagctgaatatgacaacaacaagtttaag
acgacggttgtgaatgacaatggcctaagccctgtttgggctccaacacaggagaaggtg
acatttgaaatttatgacccaaaccttgcatttctgcgctttgtggtgtacgaggaagat
atgttcagtgatcccaacttcctggctcatgctacctaccccattaaaggaattaaatca
ggatttagatctgttcctctgaagaacgggtacagcgaagacattgaactggcttccctc
ctggttttctgtgagatgcggccagtcctggagagtgaagaggagctgtactcctcctgt
cgccagctgcggaggcggcaagaagagctgaacaaccagctctttctgtatgacacacac
cagaacttgcgcaatgccaaccgggacgccctggtgaaagaattcaacgtcaacgagaac
cagctccagctgtaccaggagaagtgcaaccgcaggttaagagagaagagagtcagcaac
agcaagttttactcatag
DBGET
integrated database retrieval system
