Porphyromonas gingivalis TDC60: PGTDC60_1102
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Entry
PGTDC60_1102 CDS
T01516
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pgt
Porphyromonas gingivalis TDC60
Pathway
pgt00300
Lysine biosynthesis
pgt00550
Peptidoglycan biosynthesis
pgt01100
Metabolic pathways
pgt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pgt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PGTDC60_1102 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PGTDC60_1102 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PGTDC60_1102 (murF)
Enzymes [BR:
pgt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PGTDC60_1102 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAK25259
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Position
1141524..1142828
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AA seq
434 aa
AA seq
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MTIEQLYAAYLAHPMVTTDSRQTPPDSIFFALKGELFDGNRFASSALEKGCVLAVVDDPS
VVRDERYLLVDDVLTALQQLAAFHRKSLGTPVIGITGTNGKTTTKELMAAVLSTTYPVLY
TEGNLNNHIGVPLTLLRLKAEHRIAIIEMGANKPGDIAELTRIARPNFGLITNIGRAHLQ
GFGSLEGVRRTKGELYDFIRAEGGILFLNFDDDTLIDMSQGLQSVSYGTSADATVRGRIV
ANNTPYLCLDLFDSSNEQRVCTNLVGDYNLPNALAAITAGRFFDVPDEAIVSALTTYKPS
NNRSQWIETERGNSLIVDAYNANPVSMRAALDNFDSLHTDKPLVLILGDMNELGAESKRE
HMALLERINTGRYRQILLCGPCLAALADSFPGGATGFADNAALEEYLKAHSIHDSLILLK
GSHGIHLEKIIPLC
NT seq
1305 nt
NT seq
+upstream
nt +downstream
nt
atgacaatcgaacaattatatgcagcctatctggctcatcctatggtgactaccgacagc
cgccaaacacctcccgacagtattttcttcgctctcaagggtgagctattcgatggcaat
cggtttgcctcctctgccttggagaaaggatgcgtcttggctgtggtggacgatccttca
gtcgttcgtgacgaacgctatctccttgtggacgatgtgctgacagctctccagcagctg
gctgcttttcatcgcaagagtctcggcacaccggttataggtatcacggggacgaatggc
aaaaccacgacaaaagagctaatggctgctgtcctttccactacttatcctgtactctat
acggagggcaatctcaataaccatataggagtgcctttgactttgttgaggctcaaagcc
gaacaccggatagctattatcgagatgggagccaataagcctggagacatcgccgagctg
acacgtatagctcgtcctaactttggactgatcaccaatatcggccgggcacatttacag
ggcttcggctctctggaaggggtaaggcgtaccaagggagagctttatgatttcattcga
gcagaggggggtatcctctttctgaatttcgatgatgataccctcatcgatatgtcgcag
gggctgcaatcggtctcttacggtacctcggcagatgccacggttcgaggacgaatagtt
gcaaacaacacgccttatctttgtctcgatttattcgactcatcgaacgaacagcgggtt
tgtaccaatcttgtgggcgattacaatctgccgaacgctttggctgccataacggcagga
cgctttttcgatgtccccgatgaagccatcgtatcggctcttactacttacaaaccgagt
aataatcggtcgcaatggatcgagacggagcgaggcaattccctgattgtggatgcctat
aatgccaatccggtgagcatgcgcgctgcactcgacaatttcgattccctgcataccgat
aagcctcttgtgcttatcctcggcgacatgaacgaactgggcgcggagagcaagcgtgag
catatggctcttctcgaacgtataaataccggccgctaccggcaaatattgctatgtggg
ccttgcctcgcggctttggcagatagctttcccggtggtgcaacgggatttgctgacaat
gctgctcttgaagagtatttgaaagctcattccattcacgattccctcatcttgctcaaa
ggatcgcacggcatccacctcgaaaagataattcctttatgttga
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