Pantherophis guttatus (corn snake): 117666894 Help Entry 117666894         CDS       T07329                                  Symbol UBR4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism pgut  Pantherophis guttatus (corn snake) Brite KEGG Orthology (KO) [BR:pgut00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pgut04121]     117666894 (UBR4) Enzymes [BR:pgut01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      117666894 (UBR4) Ubiquitin system [BR:pgut04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     117666894 (UBR4) SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4_TPR UBR4_Ub UBR4 zf-UBR_1 zf-UBR Motif Other DBs NCBI-GeneID:  117666894 NCBI-ProteinID:  XP_060541262 UniProt:  A0ABM3YYQ7 LinkDB All DBs Position Unknown AA seq 5166 aa AA seqDB search MAASGGVGGGPGSSERDPGWEVAVRPLLSASYSAFEMRELPQLLASVIESESEILHHDKQ YEPFYSSFVALATHYITTVCGVVPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHL ILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKQLASPVRPELRQKEV QMNFLNQLTSVFNPKMALAPMTTLQAQGEGEGEEQAVTDQSSTAKTKSIFVAQNVASLQE LGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGFHSLVIDVTMA LDTLSLPVLEPLTPSRLQDVTVLALSCLYAGVSVATCMAILHVGTTQQVRTGSTSSKEED YENDAAIIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTTL ADKGKEKDPLAALRVRDIIVRSKEGVGSPKLGPGKGHQGFGILSVVLANHAIKLLTLLFQ DLHVEALHKGWDTDGPPAALNIMAQSTSIQRIQRLIESVPLANLLLTLLSTAYRKACVLQ RQRKGSMSSNVSASTDSNTYYEDDFSSTEDSSQDDDSEPILGQWFEETISPSKEKVAPPP PPPPPPLESSPRVKSPNKQSAGENGNILASRKDPELFLNLASNILNFLTSSMLDSKNNFI RNYLSVSLTEQHMATLASIIKEVDKDGLKGTSEEEEFAAALYHFNHSLVTSDLQSPTLQN ILLQQLGVSPFSEGPWPLYIHPQSLSVLSRFLLIWQHKASTQMDPDVPECLNVWERFVGT LKQNALQGVLPGDAEDLNVEHLQLLLLIFHSFSEKGRRSILTLCVQTILDVTANLDSQLR CVPLLLARLLLVFDYLLHQYSKAPVYLFEQVQYNLLTPPIVWAGVSQEGSRPTCSPLYHG FKEVEENWAKHCPSDAAPQPRFYCILSPEASEDDLNRLDSTVCEVLFSKAMKYDELYCAL ASLLAAGSQFDTLRRKENKSVTALEACALQYYFLILWRVLGLLPPSKSYMNQLAMNSPEM RECDILHTLRWSSRLHISSYVNWIKDHLIKQGMKTEHASSLVELTSAKCSSVKYDVEIAE EYFARQISSFCGVDCTTILQLHEIPSLQSIYTLDAAISKVQVSLDEHFSKLAAETDPHKS SEITKNLLPAALQLIDTYATFTRSYLLQSLSEDSSAENKPTEEKLQGYAAVLAIGSSRCK SNTLGPVLIQNLPSAVQSLCESWNSIHTNEFPNIGSWRNAFANDTIPAESYISAVQAAHL GTLCSQSLPLAASLKHTLLSLVRLTGDLVVWSDDLNPPQVIRTLLPLLLETSTESVAEMS SNSLERILGPAESDEFLSRVYEKLIMGCYNILANHSDPNSGLDEAILEECLQHLEKQLES SQARKAMEDFFAESGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLRLC GSLAQLACVEPARLQAWLTRMTTSPPKESDQLEMVQENRQLLQLLTTYIVRENSQVGEGA CTVLLSTLIPMATEMLANGDGTGFPELMVVMATLAGAGQGAGHLQLHSAALDWLGRCKKY LSQKNVIEKMNASVMHGKHVTILECTCHIVSYLADVTNALSQSNSQGTSHLSVDGEERAI EVDSDWVEELAAEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGV CTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQSEPR VSESVRHSSTSPTDKSKSSTSDGRGSDEDKPKKSSLCRNVEGCREQLQAQANFSFASLVL DLLNFLMEAIQINFQQASAMGSSSRAQQALNQLHTLDKTVEMTDQLMVPTLGSQEGAFEN VRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQ ADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVL HPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLLPSSKIRDITFL FNEESKNIVVIMSSAGYIYLQLMEEASSAQHGPFYVTNVLEVNHEDLKDSNGQVAGGGVS VYYSHVLQMLFFSYSQGKSFAATISRATLEVLHLFPINIKSSNGGSKTSPALCQWSEVMN HPGLLCCVQQTTGIPLVMMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMIL LCEDGSLRIYMANVENTSHWLQPALQPSSVVSIMKPVRKRKAAAIPTRSSTQVNFPIDFF EHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTLEVTNNNSTMVMTGM RVQIGTQAIERAPSYLEVFGRTLQLNLSRPRWFDFPFTREEALQADKKLTIFIGASVDPA GVTMLDAVKIYGKTKEQFGWPDEPPEDFPTASVSSVCPPNLNQGNGAGDTESATPAAVGG TVLERLVVSSLEALESWFAVGPVNEKEKTKAATQELATMLLSTPAPSSVQQQTKSLLASL HASRSAYHNHKDQALLSKAIQYLTTSNKEGKDLEPEVFQRLVITARSIAIMRPNNLVHFT ESKFPSLETESIEEGQEAAKAPEGEGCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTH VEATVNALIDILHGYCICELDCINVASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRR HVTLPSSPRSNTPMGDKDDYDDDDADDKMQTPGLPSGEDIRQESQEQNEVDHGDFEMVSE SMVLETADNVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSS SSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGS VGSESGGSAVDSVAGEHSVSGRSSAYGDTTAEGHPAGPGSISSSTGAISTATGQPEGEGS EGEGEGEGDVHASNRLHMVRLMLLERLLQTLPQLRNVGGVRAIPYMQVILMLTTDLDGDE EKDKGALDNLLAQLIAELCMEKKDVSKKNERSPLNEVHLVIMRLLSVFMSRTKSGSKSSI CESSSLISSATAAALLSSGAVDYCLHVLKSLLDYWKNQQNDEEPVPASQLLKPHTTTSPP DMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFL SEYLMIQQTPYVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRAS VVIASSGSALQYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFLLQVSFLVDEG VSPVLLQLLSCALCGSKVLSGSASAGSSGTSAPGGSSSGQPSGQSKSSTKKSKKEDKEKE REGDGSSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIYR NSNKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEKKFKEYSQKAVEIL RMQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYT TTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKK VQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNC GENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLFAKPCCAVDPIENEEDRKKAVT NINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDDSGGSGGLSSTSASVNRYIL QLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAASKSSRSAVQPTFTASQYR ALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNAAIRHILVSQGLIRELFDYNLRRG AASMREDVRQLMCLLTRDNPEATQQMNDLIISKVSAALKGHWANPDLASSLQYEMLLLTD SISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDT PVDSLTTVKPYSNEIHAQAQLWLKRDPKAAYEVWKKCLLARGLEANGKSPGRTELRHLYL TEKYAWKWKQFMSKRGKRTCPLDLKLGHNNWLRLVLFTPATQAARQAACTIVEALATIPS RKQQVLDLLTSYLDELSVAGECAAEYLALYQKLIKPARWKVYLAARGVLPYVGNLITKEI ARLLALEEATLSTDLQQGYALKSITGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLV VQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCS IIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLV ALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIE SLDSTTDEEEDEEEVYKMAGVMAQCGGLGCMLNRLTGIKDFKQGRHLLTVLLKLFSYCVK VKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEP LSEDKGNLILTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGETEKMEILVDR FKPYCSFDKYDEEHSGDDKVFLDCFCKIAAGIKNNSNGHLLKDLILQRGITQGALDYMKK HIPSAKNLDADVWKKFLSRPALPFILRLLRGLATQHPATQALIGTDSISNLHKLEQVSSD EGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQV VTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEFENKPRKQQGY STVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLA RHNTYLQECTGQREPTYQLNVHDTKLLFLRFATEQSFSVDTGGGGRESNIHLIPYIIHTV LYVLNTTRATSREEKNLQSFLEQPKEKWVEGAFEVDGPHYYTVLALHILPPERWKAVHID ILKRLLVISHARTVSPAGASKLTDKAVKDYAAYRSSLLFWALVDLIYNMFRKVPTSNTEG GWSYSLAEYIRQNDMPIYEAADRALKSFQEEFMPAETFSEFLDVAGLLSEICDPDGFLKD LFNSLP NT seq 15501 nt NT seq  +upstreamnt  +downstreamnt atggcggcgtcggggggcgtcggcggcgggcccgggtcttcggagcgggatcccggctgg gaggtggcggtgcggccgctgctgtcggcctcctactcggccttcgagatgcgcgagctg ccgcagctactggcctccgtcattgagagcgagtcggaaattctgcaccacgacaagcaa tacgagcctttctactcatcctttgttgcccttgcaacgcactacatcaccacggtgtgt ggagtggtacctcggaaccagctgcagtctgtagcagctgcctgcaaagtactgattgaa ttctccctgttgcgacttgaaaacccagacgaggcttgcgctgtctcacagaaacacctg atcctgctgatcaaggggttgtgcaccggttgcagccgcttggatcggacagagatcatc actttcacagcgatgatgaagtcggccaagctgcctcagacagtgaagaccctctcagac gtggaggatcagaaacagctggcttctcctgtcaggcctgaactgcgccagaaggaggtt cagatgaacttcctcaatcagctgacctcggtcttcaatcccaaaatggccctggcacca atgacgacgctgcaggctcagggggaaggcgaaggcgaagagcaggccgtcacagaccaa tcctccacagccaaaaccaagagtatatttgttgcccagaatgtggccagcttgcaagaa ctcggcggttctgaaaagctgctacgcgtctgcttgaatctcccgtacttcctgcgctat attaaccgcttccaggatgccgtgtcggccaattccttcttcatcatgccggctactgtt gccgacgccacagcagtccgcaacgggttccattccttggtgattgacgtcaccatggcc ctggacacgctctccctccctgtcctggaacctctgacaccctcccgcctgcaggacgtg accgttctggccctcagctgcctctatgcaggggtcagcgtggccacctgcatggccatc ctacacgtgggcaccacccagcaagtccgcacgggctccacgagctccaaagaagaggac tacgaaaacgatgccgccatcattgtacagaaatgcttagaaatctacgacatgatcggc caagccatcagcagttcccgccgtgcaggtggggagcactaccagaacttccagctactc ggggcctggtgtctgctgaacagcttattcctcatcttgaacctcagcccgaccaccctg gccgacaaagggaaagagaaggaccccctggcagcccttcgggtccgggatattattgtg cggtccaaagagggtgtcggatctcccaaacttggacctggcaaagggcaccaaggattt ggcatcctctccgtcgtcctggccaatcacgccattaagctcctcactttgctctttcaa gacctccatgtggaggcccttcacaaggggtgggacacggatggccctccggccgccctg aatatcatggcccagagtacgtcgatccagaggatccaacgcttgatcgagtcggtgcct ctcgccaacctgctgctgaccttgctgtccacagcgtatcggaaggcttgcgtcttgcag agacaacgaaaggggtccatgagcagcaacgtcagcgcctccacggactccaacacctac tacgaagacgacttcagcagcacggaagacagcagccaagacgatgacagcgagccgatc cttgggcagtggttcgaagagaccatctcccccagcaaggagaaagtggcccctcctccc cctcctcccccaccccctctggagagctccccccgggtgaagagccccaacaagcagtcg gcaggagaaaacgggaacatcctggccagtcgcaaagacccggaattgttcttaaatctg gcctccaacatcctcaacttcctaacttcctccatgctggactcgaagaacaatttcatt cgcaactacctgagcgtgtctctgacggagcagcacatggccaccctggccagcatcatc aaagaagtggacaaggatgggctcaaagggacctccgaagaggaagagtttgcggctgcg ctgtaccatttcaaccattccttggtgacctctgatctccagtctccgaccttgcagaat attctcctgcaacagctgggggtgtctcctttctccgaagggccgtggcctctctacatc cacccccagagcttgtccgtgctctcccgttttctcctcatctggcagcataaagccagc acccagatggacccggatgtcccagagtgtctgaatgtgtgggagaggtttgtgggcact ttgaagcaaaacgccctgcagggggttcttcccggcgacgcagaggacctcaacgtggag cacctccagctcctgctgctcatcttccacagcttctccgaaaaaggccggcggtccatc ctgaccctctgcgtccagaccatcctggacgtgacagccaacctggactctcagctccga tgcgtccctctcctgctcgcccgccttctcttggtcttcgactacctgcttcaccaatac tcaaaggctcccgtgtatttatttgagcaggtccagtacaacctcttaactccccccatc gtttgggccggcgtgagccaggagggcagccgaccgacctgttccccactttatcacggc ttcaaggaagtggaagaaaactgggccaagcactgtccctctgacgctgccccccagcca cgcttctactgcattctctccccggaagcatctgaagatgacttgaatcgcctcgatagc acggtgtgcgaagtcttgttctccaaggccatgaaatacgacgagctctactgcgccctg gcttcgctgctggctgccggctcccagtttgacaccctccggcggaaggagaacaaaagc gtcaccgccttggaggcctgcgcgcttcagtattacttcctgattctttggcgggtcttg ggcctccttcccccgtccaagagctacatgaatcagctggccatgaacagcccggagatg cgggaatgcgacatcctccacaccctgcgctggtcttcccgcctccacatctcctcctat gtcaactggatcaaggaccacctcatcaaacaagggatgaaaactgagcacgcctcttcc ctggtcgagctgacttcggccaaatgcagctccgtcaagtacgacgtggagatcgcagag gaatatttcgccagacagatctcctctttctgcggggtcgactgcaccaccatccttcag ctgcacgagatccccagcttgcagtccatctataccttggacgcggccatttccaaagtc caggtctcgctggacgagcacttctccaagctggctgccgaaaccgacccccacaaatcc tcggagatcaccaagaacctgctgccagccgccctgcagctgatcgatacctacgccacc ttcaccagatcttacctgcttcagagcctttccgaggacagctcggcagagaacaaaccc accgaagagaagctgcaaggatacgctgccgtgctggccattggctccagtcgctgcaaa tccaatactctggggccggttctgatccagaatttgccgtccgccgtccagtcgctatgc gaatcctggaacagcattcataccaacgagttccccaacattgggtcttggcgcaacgcc tttgccaacgacacaatcccggccgagagctacatcagcgccgttcaggccgcccacctg ggcaccctgtgcagtcagagccttcccttggcggcctcgttgaagcacaccctcctctcc ttggtcagactcaccggagaccttgtggtctggtccgatgacctgaacccgccccaggtg atccgcacactgctgcctctccttctggagaccagcacagagagcgtggccgagatgagc agcaattccctggagaggatcctgggcccggcagagtcggacgagttcctctcgcgggtc tacgagaagctgatcatgggctgctacaacattctggccaatcactccgacccgaacagc ggcctcgacgaagccatcttggaggaatgtctgcaacatctggagaaacagctggagagc agccaggcccggaaagccatggaggatttttttgcggagagtggagagctggtccagatc atgatggcaaccgccaacgagaacctctcggccaaattctgcaaccgggttctgaaattc ttcaccaagctcttccagctaaccgagaagagcccaaaccccagccttctgcgcttgtgt ggctccttggcccagctggcgtgcgtggagcctgcacgcctccaggcgtggttgacccgt atgaccacctctccccccaaggagtctgaccagctggagatggtgcaggaaaaccgacaa ctgctccaactcctgaccacctacatcgtgcgggagaacagccaagtcggcgagggagcc tgcactgtcctcctgagtaccctgattcccatggctaccgagatgttggcaaatggagac gggaccggctttccagagcttatggtggtcatggcgacccttgccggagccggacaagga gctggtcacctccagctgcacagtgcagcgctggactggctggggagatgcaagaaatat ttgtctcagaagaatgtgattgagaaaatgaacgccagcgtcatgcacgggaagcacgtg actatcctggagtgcacctgtcacattgtctcctacctggccgacgtcaccaatgccctg agccagagcaacagccaaggcaccagccacctctcggttgacggagaagagcgggccatc gaagtggactccgactgggtggaggaactggccgcggaggaggaggactcacaggctgaa gactcggacgaagactctctctgcaacaaactttgtacctttaccatcacgcagaaggaa ttcatgaatcagcactggtatcactgccacacctgcaaaatggtggatggtgtcggcgtg tgcaccgtctgcgccaaggtttgccacaaggaccacgagatttcgtatgcgaaatacgga tcgttcttttgtgactgcggagccaaggaggatggcagctgcctggccctggtgaagagg actcccagcagcggcatgagctccaccatgaaggagtcggccttccagagcgagcctcgc gtctcggagagcgtccgccattccagcacctcgcccaccgacaagtccaagtcctccacc agcgatggccgagggagcgacgaagacaagcccaagaagagcagcctctgcaggaacgta gaaggttgtcgggagcagttgcaggcccaggccaacttctccttcgcctctttggtcctc gacctgctcaacttcctgatggaggccatccagatcaacttccagcaagcctcggcgatg ggcagcagcagccgcgcccagcaggcgttgaaccagctgcacaccttggacaagacggtg gaaatgaccgaccagttgatggtgccgactctgggctctcaggaaggcgcctttgagaac gtccggatgaactacagcggagaccaaggccagaccatccggcagctgatcagcgcccac gtcctgcggcgggtggccatgtgcgtgctttcctcgcctcacggacggcgccagcacctg gcagtcagccacgagaagggcaagatcaccgtgctgcagctctctgcgctgctgaagcaa gctgattccagcaagaggaagttgacgctgacccgcctggcctccgcacccgtccccttc acggtcctgagcttgaccgggaatccctgcaaggaggactatctggctgtttgtggcttg aaggactgccacgtcctcacattcagcagttcgggctccgtctcggatcacttggtgctc caccctcagcttgccacgggcaatttcatcatcaaggcagtctggcttccgggatcccag acggaactggccatcgtcactgccgactttgtcaagatctacgacctctcggtggacgcc ttgagccccactttctacttcctgctgcccagctccaaaatccgggacatcactttcctc ttcaatgaagagagcaagaacattgtggtcatcatgtcctctgcgggctacatctatctg caactcatggaggaggccagcagcgcccagcacggccctttctacgtcaccaacgtcctc gaagtcaaccacgaggacctgaaggacagcaatggccaggtggccgggggcggagtgtcc gtctactactcccacgtcctgcagatgcttttcttcagctacagccaagggaagtccttt gcggccaccatcagccgagctaccttggaggtattacacctctttcccatcaacatcaaa agctctaacgggggcagcaagacctccccggccctttgccagtggtcagaggtcatgaac caccccggcctcttgtgctgcgtgcaacagaccaccggcattcctctcgtcatgatggtg aagcccgacactttcctgatccaagagatcaagaccttaccggcgaaagccaagatccaa gacatggtagccatccgtcacacggcctgcaacgagcagcagcggacgaccatgatcctc ctctgcgaggacggcagcctgcggatctacatggccaacgtggagaacacctcccactgg ctccagcccgccctgcagcccagcagcgtggtcagcatcatgaagcccgtccgcaagcgc aaagcggcagccatccccacccgcagctccacccaggtgaacttccccatcgacttcttt gaacacaaccagcagctgacagacgtggagttcgggggcaacgacctcctgcaggtctac aatgcccagcagatcaagcaccgtctcaactccaccggcatgtacgtggccaacaccaag cccgggggcttcaccctcgaggtgaccaacaacaacagcaccatggtgatgactggcatg agggtccagatcgggacacaagccatcgagagagctccttcctacctggaagtcttcggc cgcaccttgcagctcaacctcagccgcccccggtggttcgatttcccctttactcgtgag gaagccctgcaggccgacaagaagctgaccattttcatcggggcctctgtggaccccgcc ggagtcaccatgctggacgccgtcaagatctacggcaagaccaaggagcagtttggttgg ccggacgaacccccggaggacttcccgacggcatccgtgagcagtgtctgccccccaaac ctgaatcaagggaacggggccggagatacggaatcggcgacccctgcagccgtgggcggc accgtcttggagaggctagtagtgagttctttagaagccctggaaagttggtttgccgtc ggaccagtcaacgagaaggagaagaccaaggctgccactcaggagttggccaccatgctg ctgtctacaccggccccttccagcgtccagcagcagaccaagagcctgctggccagcctc catgccagccgctcagcttaccacaaccacaaggatcaggccctgttgagcaaagccatc cagtacctcaccacctcgaacaaagaagggaaggatctggaaccggaggtctttcagaga ttggtcatcacggcccgctccatcgccatcatgcggccgaataacctggtccatttcacg gagtcgaagtttccgtctctggaaacagaaagcatcgaagaaggtcaggaggctgcgaag gccccggaaggagaagggtgcagttttatcacccaactggtcaaccatttctggaaactt cacgcctccaaacccaagaacgccttcctggcgcctgcatgcttgccagggctgacccac gtcgaggccaccgtcaacgccctcatagacatcctccacggatattgcatctgcgagctg gactgcatcaatgtcgcctccaaaatctacatgcagatgttgctgtgcccggatccggct gtgagtttctcgtgcaagcaagcgctgatccgggtgctgaggcccaggaacaagaggaga cacgtgaccttgccttcttctcctcgaagcaacacccccatgggcgacaaagacgattat gacgacgacgatgctgatgacaagatgcagacccccggcctgcccagcggggaggacatt cggcaggagagccaggagcaaaatgaggtggaccatggagactttgagatggtgtctgaa tcgatggtcctggaaactgccgacaacgtgaacaacgggaacccgtctcccctggaggct ctcctggctggggccgagggcttcccccccatgctggacatcccccccgatgccgacgac gaaaccatggtcgagctggccattgccttgagcctgcaacaggaccagcagggcagcagc agcagcgctctcggcttacagagcctggggctgtctggacaggcccccagctcttcctct ctggatgccgggactctgtcagataccactgcatcagctccagcctccgacgacgaaggc agcacggctgcgaccgacggctccacgctccgcacctccccagccgaccacgggggcagc gtgggctctgagagcgggggcagcgcagtggactccgtggcaggcgagcacagtgtgtcc ggccgaagcagcgcctacggagacacgacggctgagggccatccggcagggcctgggagc atcagctccagcacgggggccatcagcaccgccacggggcagccggagggtgaaggctct gaaggcgagggcgaaggcgaaggggacgtccacgccagcaacaggttgcacatggtcagg ctaatgctgctggaacggctactgcagacccttcctcagctgaggaacgttggcggggtc cgggccatcccctacatgcaggtgatcctgatgctgaccactgaccttgatggcgatgaa gaaaaagacaaaggggcactggataaccttctcgcccagttgattgctgagctctgcatg gagaagaaggacgtgtccaagaaaaatgaacgctctcccctcaacgaagtccacctggtt atcatgaggctcttgagtgtcttcatgtcccggacaaaatctggatcaaaatcttccatt tgtgagtcgtcctccctgatttcgagtgccaccgcggcggctttgctgagctccggagcc gtggactattgccttcacgtcctgaagtccctgttggactactggaagaaccagcagaac gacgaggagcctgtgcccgccagccagctcctgaagccccacaccaccacctctcctccc gacatgagtcctttctttctgcgacagtatgtcaagggtcacgcggccgacgtcttcgag gcctacactcagcttctgacagagatggtcctgcggctgccctatcagatcaaaaagatc gccgacaccaactcccgcattccgccccccgtcttcgatcattcgtggttctacttcttg tccgagtacctgatgatccagcagaccccctacgtgcggcgtcaggtgcgcaaactcctc ctcttcatctgcggctccaaggagaagtaccgccagctgcgggacctgcacaccctcgat tcccacgtccgggggatcaagaagctgctggaggagcaaggcattttcctgagggccagc gtggtcatcgccagctccggctccgccctgcagtacgacacccttatcagtttgatggag cacctgaaggcctgtgccgaaattgccacccagcgcacggtcaactggcaaaaattctgc atcaaagacgattccgtcctctatttcctcctgcaagtcagcttcctggtcgatgagggt gtctcaccggtcctcctccagctactctcctgcgccctctgtggcagcaaggttctctct gggtcggcttcggccgggtcttcaggcacttcagcccccggagggtccagctcaggccag ccatccgggcagagcaaatcctccaccaagaagagcaagaaggaagacaaggagaaggag cgagagggagacggctcctcgggcagccaggaagaccagctctgcaccgctctggtgaac cagctgaacaaatttgccgacaaagagacgctgattcagttcctgcgctgcttcctgctg gaatccaactcatcgtccgtgcgttggcaggctcactgtctcactctgcacatctaccgg aactccaacaagtcccagcaagagctgctgctggacctgatgtggtcgatctggccagag ctgccggcttacgggcggaaggcagcccagtttgtggacctcctgggctacttctctctg aaaacccaacagacggagaaaaagttcaaggaatactcccagaaggctgtggagatcctc aggatgcagaaccacatcctcaccaatcaccccaactccaacatctacaacaccctctcc ggcctggtggagtttgacggctactacttagagagcgacccctgtctcgtttgcaacaac ccggaagtgcctttctgctacatcaagctgtcctccatcaaggtggacacccgttacaca accacccagcaagtggtcaagctcatcggcagccacaccatcagcaaagtgacggtcaag attggagacctgaagcgcaccaagatggtccggaccatcaacctctactacaacaaccgg accgtgcaggccatcgtggagctgaagaacaagccggcccgctggcacaaagccaagaag gtccagctgacccccggccagacggaagtgaagatcgaccttcccctgcccatcgtggcc tccaatctgatgatcgaatttgccgacttctacgagaactaccaggcctccacggaaacc ttgcagtgcccccgatgcagcgcctcggtccccgccaaccccggagtctgcggaaactgt ggggagaacgtctaccagtgccacaagtgccggtcgatcaactacgatgagaaggacccc tttctctgcaacgcctgcggcttctgcaaatacgcccgctttgatttcatgctgttcgcc aaaccgtgctgcgccgtggaccccatcgagaacgaagaggaccggaagaaggccgtgacc aacatcaacaccctcctggacaaggccgaccgggtctaccaccagctgatgggccaccga cctcagttggagaacctgctctgcaaagtgaacgaggcggcgcccgaaaagccacaggat gactccgggggcagtggaggcctcagctccacctcagccagcgtgaacaggtacatctta cagctggcgcaggagtactgtggcgactgcaagaactcctttgacgagctctccaagatc atccagaaagtgtttgcctcccggaaggagctcctggagtacgacctccagcagagagag gccgccagcaagtcctcccgctcggctgtccagcccaccttcaccgccagccagtaccgc gccctctcggtcttgggttgcggccacacctcctccaccaaatgctacggctgtgcctca gccgtcaccgagcactgcatcacgctgctccgcgccttggccaccaacgccgccatccgc cacatcctggtctcccagggcctcatccgcgagctcttcgactacaacctgcgccgaggg gctgccagcatgagggaggacgtccgccagctcatgtgcctcctcactagagacaaccca gaagccacacagcagatgaacgacctcatcatcagcaaagtgtccgcagctctgaagggc cattgggccaatcctgatctggccagcagccttcagtacgagatgctgctgctgacggac tccatctccaaagaggacagttgctgggaattgcgcctgcgttgcgccctcagcctcttc ctcatggccgtgaacatcaagacgccggtggtggtggaaaacatcaccctgatgtgtcta cggatccttcagaagctgatcaagcccccggcgcccaccagcaagaagaacaaggacacg ccggtggactccctgaccacggtcaagccctacagcaatgagatccacgcccaggcccag ctgtggctcaagagggatcccaaggccgcctacgaggtgtggaagaagtgcctccttgcc agaggccttgaagccaacgggaaatctcccgggcgaacggagctccgccacctctacctg acggagaagtacgcctggaagtggaagcagttcatgagcaagcgggggaagaggacctgc cccctggacctcaagctgggacacaacaattggctgcggctggtcttgttcaccccagca acccaagcagcccggcaggcagcttgcaccatcgtggaagccttggccaccatccccagc cgcaagcagcaagtcctcgacctgctgaccagctacctggacgagctgagcgtggcgggc gagtgtgccgccgagtacctggccctctaccagaagctcatcaagccggcccgctggaag gtctacctggcggccaggggggtcctgccttatgtcggcaatctgatcaccaaggaaatc gcccgtctcctggccctggaggaagccaccctcagcaccgacctgcagcagggctacgct ctcaagagcatcaccggcctcctgtcctccttcgtggaagtcgagtccatcaagcgccac ttcaagagccggctggtggggacggtgctcaacggctacctctgcttgcggaaactggtg gtgcagcgcaccaagctgatcgacgagacccaggacatgttgctggagatgctggaagac atgaccacaggcacagagtccgagaccaaggctttcatggccgtctgcatcgaaaccgcc aaacgctacagcctggacgactaccggacgcccgtcttcatcttcgagagactctgtagc atcatctacccggaggagaacgaagtgacggagttcttcgtcacgctggagaaggaccct cagcaagaggatttcctgcagggccggatgcccgggaacccctacagcagcaacgagccg ggcatcgggccgctgatgagggacatcaagaacaagatctgccaggactgcgacttggtg gctctgctggaagacgacagcgggatggagcttctggtgaacaacaagatcatcagcttg gatctcccggtggccgaagtgtacaagaaagtctggtgcccgacaaacgagggcgagccc atgaggataatttatcgcatgcggggcctgttgggggatgccacggaagaattcatagaa tcgctggattccactacagatgaagaggaggacgaggaagaggtgtacaagatggcggga gtcatggcgcaatgcggcggtctgggctgcatgctgaaccgcttgaccgggatcaaagac ttcaaacaaggccggcatctgctgacggtcctgctgaagctcttcagctactgcgtcaaa gtgaaggtcaaccgccagcagctggtgaagttggagatgaacacgctcaacgtcatgctg gggacgctgaacttggctttggtggccgagcaggaaagcaaggacagcggaggagcggcg gtggcagaacaagtcctcagcatcatggagattatcctggacgagtccaacgcggagccg ctgagtgaggacaagggcaacctgatcctgacgggcgacaaggaccagctggtgatgcta ctggatcagatcaacagtacatttgtccgctccaaccccagcgtgctccagggcctcctg cgcatcatcccttacctgtccttcggggagacggagaagatggagatcctggtggaccgt ttcaagccctactgcagcttcgacaagtacgacgaagaacacagcggcgacgataaagtc tttctggactgtttctgcaaaattgcagctggcatcaagaacaacagcaacgggcacctg ctgaaggacctcatcctgcagagagggattacccagggcgccttggactacatgaagaag catatccccagcgccaagaatttggatgccgatgtgtggaagaagtttctgtctcgaccg gccctcccgtttatcctgcggctgctccgaggactcgccacccagcatccggccacccag gctctgattgggaccgattcgatctccaacttgcacaagctggagcaggtctccagtgac gaaggcatcgggacgctggccgagaacctcctggaagctctgcgggagcacccggacgtc aacaagaagatcgacgcggcccgcagggagacacgggcagagaagaagcggatggccatg gccatgcggcagaaggccctgggcaccctcggcatgacgacgaacgaaaagggtcaggtg gtgacgaagacggcgctgctgaagcagatggaggagctgatcgaagagcccggcttgacg tgctgcatctgtcgggaaggctacaagttccagcccaccaaggtcctgggcatttacacc ttcaccaagcgggtagccctggaggagtttgagaacaagcctcggaagcaacagggctac agcaccgtctcccacttcaacatcgtccactacgattgccacctggccgcggtcaggttg gcgcggggtcgcgaggagtgggagagcgccgccctgcagaacgccaacaccaaatgcaac ggcctcctgccagtctgggggccgcacgtcccggaatctgcctttgccacctgcttggca aggcacaacacttacctccaggagtgtacggggcagcgggagcccacctaccagctcaac gtgcacgacaccaagctgctcttcctccggttcgccacggaacagtcgttcagcgtggac acgggcggcggcgggcgggagagcaacattcacctgatcccctacatcattcacacagtg ctttacgtcctcaacacgacgcgggcgacctctcgagaggagaagaacctgcagagcttc ctggaacagccgaaggagaagtgggtggagggagcctttgaggtggacggcccccattac tacaccgtcttggcgcttcacatcctgccccccgagcggtggaaggcggtgcacatcgac atcctgaagcgtctgctggtcatctcccacgcccggacggtgtccccggcgggagccagc aagctaacggacaaagccgtgaaggactacgcggcctatcgctccagcctcctcttctgg gccctggttgatctcatttacaacatgttcagaaaggtgcctacgagcaacacagagggg ggctggtcctactctctggccgagtacatccgccagaacgacatgcccatctacgaggcg gccgacagagccctcaagtccttccaggaggagttcatgcccgcggagaccttctcagaa ttcctggacgtggctggattgttatccgaaatctgcgaccccgacggcttcctcaaagat ctcttcaactctcttccctga

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