| Entry |
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| Symbol |
IL6R
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| Name |
(RefSeq) interleukin-6 receptor subunit alpha
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| KO |
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| Organism |
phas Phyllostomus hastatus (greater spear-nosed bat)
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| Pathway |
| phas01521 | EGFR tyrosine kinase inhibitor resistance |
| phas04060 | Cytokine-cytokine receptor interaction |
| phas04061 | Viral protein interaction with cytokine and cytokine receptor |
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| Brite |
KEGG Orthology (KO) [BR:phas00001]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
123804359 (IL6R)
04066 HIF-1 signaling pathway
123804359 (IL6R)
04151 PI3K-Akt signaling pathway
123804359 (IL6R)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
123804359 (IL6R)
04061 Viral protein interaction with cytokine and cytokine receptor
123804359 (IL6R)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
123804359 (IL6R)
04659 Th17 cell differentiation
123804359 (IL6R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123804359 (IL6R)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
123804359 (IL6R)
05163 Human cytomegalovirus infection
123804359 (IL6R)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
123804359 (IL6R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123804359 (IL6R)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:phas04050]
123804359 (IL6R)
04090 CD molecules [BR:phas04090]
123804359 (IL6R)
Cytokine receptors [BR:phas04050]
Interleukin receptor families
IL6/12 receptor family
123804359 (IL6R)
CD molecules [BR:phas04090]
Proteins
123804359 (IL6R)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
468 aa
MLAVRCALLTALLAAPGAALVPGVCPALEVESDVLTSRPGGSVALVCPGVDPEDNATVHW
VLRKQVSGSRRSTWAGMGRRLVLRRVLLSYSGNYSCYQNGHRVGIVRLLVEAPPEKPQLS
CFRKSPVNDVACEWSPRSAPSQRTEAMLLVRRLQHGPAKDFQEQCQYSQESQKFSCQLAV
PEGDNAFYIVSLCVTNSAGNESSRPQTFEGYEILQPDPPVNITVAAVDRNPRWLSVSWQD
PPSWNTYFYRLQFELRYRAKRSKTFTTWMVKDLQHHCIIHDAWKGMEHVVQLRAQEEFGH
GQWSEWSQEVTGTPWTEPMSSLTETKVEVSPSTEAFTVGKDDENTSYYSTNATSFPVRDS
PVPLYTFLVAGGSLAFGTLLCIGIILRFKKTWKLQALKEGKTSMHPPYSLGQLVPERPKP
TPVLAPLISPPVSPSSLGSDSTSRHSRPDAQGPQSQYDISNRDYFFPQ |
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| NT seq |
1407 nt +upstreamnt +downstreamnt
atgctggcggtccgctgcgccctgctcaccgccctgctggccgcgccgggggcggcactg
gtcccaggggtctgccccgcgctggaggtggagagtgacgtgctgaccagcaggcccgga
gggagcgtcgccctggtctgcccgggcgtggatccggaagacaatgccacggttcactgg
gtgctcaggaagcaggtctcgggctcacgccgtagcacctgggctggcatgggaaggagg
ctggttctgaggcgcgtgctgctcagctactctggaaactactcgtgctaccagaacggc
caccgggttggaattgtgcgcctgctggtggaggctcctccagagaagccccagctctcc
tgcttccggaagagccccgtgaacgacgtggcctgtgagtggagtcctcggagcgccccc
tcccagaggactgaggctatgttactggtgaggaggctgcagcacgggccggcgaaggac
ttccaggagcagtgccagtactcccaggagtcccagaagttctcctgccagttggcagtc
ccagagggagacaacgctttctacattgtgtccctgtgtgtcaccaacagtgctgggaac
gagtccagcagaccccaaacatttgagggttacgaaatcttgcagcctgacccacccgtc
aacatcaccgtcgctgccgtggacagaaacccccgctggctcagtgtcagctggcaagac
cccccctcctggaacacatacttctacaggctgcagtttgagctccgataccgggctaaa
cggtcaaagacatttacgacatggatggtcaaggatctccagcatcactgcatcatccac
gacgcctggaaaggcatggagcacgtggtgcagctgcgggcccaggaggagtttggacat
ggtcagtggagcgagtggagccaggaggtcacggggactccctggacagagcccatgagt
tctttaactgagaccaaggtggaggtgtctccctccacggaggcatttactgttggtaaa
gatgatgaaaatacttcctattattccacaaatgctacaagcttcccagtgcgagattct
ccagtaccactgtacacattcctggtggctggaggaagcctggcctttgggacgctcctt
tgcattggcatcatcctgaggttcaagaagacgtggaagctacaggctctgaaagaaggc
aagacgagcatgcacccaccttattctctgggacagctggtccccgagaggcccaagccc
acacccgtgctggcgcccctcatctccccaccagtgtcccccagcagccttgggtccgac
agcacctcgaggcacagccgacccgatgcccagggcccgcagagccagtatgacatcagc
aacagagactatttcttcccccagtag |
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