KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123806902
Entry
123806902         CDS       T07912                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01522  Endocrine resistance
phas04010  MAPK signaling pathway
phas04012  ErbB signaling pathway
phas04014  Ras signaling pathway
phas04024  cAMP signaling pathway
phas04068  FoxO signaling pathway
phas04071  Sphingolipid signaling pathway
phas04137  Mitophagy - animal
phas04140  Autophagy - animal
phas04141  Protein processing in endoplasmic reticulum
phas04210  Apoptosis
phas04215  Apoptosis - multiple species
phas04217  Necroptosis
phas04310  Wnt signaling pathway
phas04380  Osteoclast differentiation
phas04510  Focal adhesion
phas04530  Tight junction
phas04620  Toll-like receptor signaling pathway
phas04621  NOD-like receptor signaling pathway
phas04622  RIG-I-like receptor signaling pathway
phas04625  C-type lectin receptor signaling pathway
phas04657  IL-17 signaling pathway
phas04658  Th1 and Th2 cell differentiation
phas04659  Th17 cell differentiation
phas04660  T cell receptor signaling pathway
phas04664  Fc epsilon RI signaling pathway
phas04668  TNF signaling pathway
phas04722  Neurotrophin signaling pathway
phas04723  Retrograde endocannabinoid signaling
phas04728  Dopaminergic synapse
phas04750  Inflammatory mediator regulation of TRP channels
phas04910  Insulin signaling pathway
phas04912  GnRH signaling pathway
phas04914  Progesterone-mediated oocyte maturation
phas04917  Prolactin signaling pathway
phas04920  Adipocytokine signaling pathway
phas04926  Relaxin signaling pathway
phas04930  Type II diabetes mellitus
phas04931  Insulin resistance
phas04932  Non-alcoholic fatty liver disease
phas04933  AGE-RAGE signaling pathway in diabetic complications
phas04935  Growth hormone synthesis, secretion and action
phas04936  Alcoholic liver disease
phas05010  Alzheimer disease
phas05012  Parkinson disease
phas05016  Huntington disease
phas05017  Spinocerebellar ataxia
phas05020  Prion disease
phas05022  Pathways of neurodegeneration - multiple diseases
phas05132  Salmonella infection
phas05133  Pertussis
phas05135  Yersinia infection
phas05142  Chagas disease
phas05145  Toxoplasmosis
phas05152  Tuberculosis
phas05161  Hepatitis B
phas05162  Measles
phas05166  Human T-cell leukemia virus 1 infection
phas05167  Kaposi sarcoma-associated herpesvirus infection
phas05169  Epstein-Barr virus infection
phas05170  Human immunodeficiency virus 1 infection
phas05171  Coronavirus disease - COVID-19
phas05200  Pathways in cancer
phas05208  Chemical carcinogenesis - reactive oxygen species
phas05210  Colorectal cancer
phas05212  Pancreatic cancer
phas05231  Choline metabolism in cancer
phas05415  Diabetic cardiomyopathy
phas05417  Lipid and atherosclerosis
phas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:phas00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    123806902 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123806902 (MAPK10)
   04012 ErbB signaling pathway
    123806902 (MAPK10)
   04014 Ras signaling pathway
    123806902 (MAPK10)
   04310 Wnt signaling pathway
    123806902 (MAPK10)
   04668 TNF signaling pathway
    123806902 (MAPK10)
   04068 FoxO signaling pathway
    123806902 (MAPK10)
   04071 Sphingolipid signaling pathway
    123806902 (MAPK10)
   04024 cAMP signaling pathway
    123806902 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123806902 (MAPK10)
   04137 Mitophagy - animal
    123806902 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    123806902 (MAPK10)
   04215 Apoptosis - multiple species
    123806902 (MAPK10)
   04217 Necroptosis
    123806902 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123806902 (MAPK10)
   04530 Tight junction
    123806902 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123806902 (MAPK10)
   04621 NOD-like receptor signaling pathway
    123806902 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    123806902 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    123806902 (MAPK10)
   04660 T cell receptor signaling pathway
    123806902 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    123806902 (MAPK10)
   04659 Th17 cell differentiation
    123806902 (MAPK10)
   04657 IL-17 signaling pathway
    123806902 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    123806902 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123806902 (MAPK10)
   04920 Adipocytokine signaling pathway
    123806902 (MAPK10)
   04912 GnRH signaling pathway
    123806902 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    123806902 (MAPK10)
   04917 Prolactin signaling pathway
    123806902 (MAPK10)
   04926 Relaxin signaling pathway
    123806902 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    123806902 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    123806902 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    123806902 (MAPK10)
   04722 Neurotrophin signaling pathway
    123806902 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123806902 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123806902 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123806902 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    123806902 (MAPK10)
   05231 Choline metabolism in cancer
    123806902 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123806902 (MAPK10)
   05212 Pancreatic cancer
    123806902 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123806902 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    123806902 (MAPK10)
   05161 Hepatitis B
    123806902 (MAPK10)
   05171 Coronavirus disease - COVID-19
    123806902 (MAPK10)
   05162 Measles
    123806902 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123806902 (MAPK10)
   05169 Epstein-Barr virus infection
    123806902 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123806902 (MAPK10)
   05135 Yersinia infection
    123806902 (MAPK10)
   05133 Pertussis
    123806902 (MAPK10)
   05152 Tuberculosis
    123806902 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123806902 (MAPK10)
   05142 Chagas disease
    123806902 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123806902 (MAPK10)
   05012 Parkinson disease
    123806902 (MAPK10)
   05016 Huntington disease
    123806902 (MAPK10)
   05017 Spinocerebellar ataxia
    123806902 (MAPK10)
   05020 Prion disease
    123806902 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    123806902 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123806902 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    123806902 (MAPK10)
   05415 Diabetic cardiomyopathy
    123806902 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    123806902 (MAPK10)
   04936 Alcoholic liver disease
    123806902 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    123806902 (MAPK10)
   04931 Insulin resistance
    123806902 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123806902 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123806902 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:phas01001]
    123806902 (MAPK10)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     123806902 (MAPK10)
Protein kinases [BR:phas01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   123806902 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 123806902
NCBI-ProteinID: XP_045676312
LinkDB
Position
Unknown
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAALDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttactatactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggatttgacaaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccaattctacagcgtggaagtaggagactcaaccttcacagtt
ctcaagcgttaccagaatctaaaacctattggctctggggctcagggaatagtttgtgct
gcatatgatgctgcccttgacagaaatgtggccattaagaagctcagcagaccatttcag
aaccaaacgcacgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aaaaatattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccaa
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgaacggatgtcttaccttctataccaaatgttgtgtggcatcaagcacctt
cattctgctggaattattcacagggatctaaaaccaagtaacattgtagtcaagtctgat
tgtaccttgaaaattctcgactttggactggccaggaccgcaggcacaagcttcatgatg
actccttatgtggtgacacgttattacagagcccctgaggtcatcctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaagtaattgagcaactagga
acaccatgtccagaattcatgaagaaattgcagcccacagtaagaaactatgtggagaat
cggcctaagtatgcaggactcaccttccccaagctctttccagattccctctttcctgct
gattctgagcacaataaactcaaagccagccaagccagggacttgttgtcaaagatgcta
gtgattgaccctgccaagaggatatcagtggatgatgccttacagcatccatacatcaat
gtttggtacgaccctgctgaagtggaggcgcctccacctcagatatatgacaaacagttg
gatgaaagagaacacaccattgaagaatggaaagaacttatctacaaggaagtaatgaac
tcagaagaaaaaactaaaaatggtgtcgtaaaaggacagccctctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcctcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcggcgggacccctg
ggttgttgcaggtga

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