Phyllostomus hastatus (greater spear-nosed bat): 123807983
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Entry
123807983 CDS
T07912
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521
EGFR tyrosine kinase inhibitor resistance
phas01522
Endocrine resistance
phas04010
MAPK signaling pathway
phas04012
ErbB signaling pathway
phas04014
Ras signaling pathway
phas04062
Chemokine signaling pathway
phas04068
FoxO signaling pathway
phas04072
Phospholipase D signaling pathway
phas04150
mTOR signaling pathway
phas04151
PI3K-Akt signaling pathway
phas04510
Focal adhesion
phas04540
Gap junction
phas04630
JAK-STAT signaling pathway
phas04650
Natural killer cell mediated cytotoxicity
phas04660
T cell receptor signaling pathway
phas04662
B cell receptor signaling pathway
phas04664
Fc epsilon RI signaling pathway
phas04714
Thermogenesis
phas04722
Neurotrophin signaling pathway
phas04810
Regulation of actin cytoskeleton
phas04910
Insulin signaling pathway
phas04912
GnRH signaling pathway
phas04915
Estrogen signaling pathway
phas04917
Prolactin signaling pathway
phas04926
Relaxin signaling pathway
phas04935
Growth hormone synthesis, secretion and action
phas05034
Alcoholism
phas05160
Hepatitis C
phas05161
Hepatitis B
phas05163
Human cytomegalovirus infection
phas05165
Human papillomavirus infection
phas05200
Pathways in cancer
phas05205
Proteoglycans in cancer
phas05206
MicroRNAs in cancer
phas05207
Chemical carcinogenesis - receptor activation
phas05208
Chemical carcinogenesis - reactive oxygen species
phas05210
Colorectal cancer
phas05211
Renal cell carcinoma
phas05213
Endometrial cancer
phas05214
Glioma
phas05215
Prostate cancer
phas05220
Chronic myeloid leukemia
phas05221
Acute myeloid leukemia
phas05223
Non-small cell lung cancer
phas05224
Breast cancer
phas05225
Hepatocellular carcinoma
phas05226
Gastric cancer
phas05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
123807983 (SOS2)
04630 JAK-STAT signaling pathway
123807983 (SOS2)
04068 FoxO signaling pathway
123807983 (SOS2)
04072 Phospholipase D signaling pathway
123807983 (SOS2)
04151 PI3K-Akt signaling pathway
123807983 (SOS2)
04150 mTOR signaling pathway
123807983 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
123807983 (SOS2)
04660 T cell receptor signaling pathway
123807983 (SOS2)
04662 B cell receptor signaling pathway
123807983 (SOS2)
04664 Fc epsilon RI signaling pathway
123807983 (SOS2)
04062 Chemokine signaling pathway
123807983 (SOS2)
09152 Endocrine system
04915 Estrogen signaling pathway
123807983 (SOS2)
04917 Prolactin signaling pathway
123807983 (SOS2)
04926 Relaxin signaling pathway
123807983 (SOS2)
04935 Growth hormone synthesis, secretion and action
123807983 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
123807983 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
123807983 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123807983 (SOS2)
05206 MicroRNAs in cancer
123807983 (SOS2)
05205 Proteoglycans in cancer
123807983 (SOS2)
05207 Chemical carcinogenesis - receptor activation
123807983 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
123807983 (SOS2)
05231 Choline metabolism in cancer
123807983 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
123807983 (SOS2)
05225 Hepatocellular carcinoma
123807983 (SOS2)
05226 Gastric cancer
123807983 (SOS2)
05214 Glioma
123807983 (SOS2)
05221 Acute myeloid leukemia
123807983 (SOS2)
05220 Chronic myeloid leukemia
123807983 (SOS2)
05211 Renal cell carcinoma
123807983 (SOS2)
05215 Prostate cancer
123807983 (SOS2)
05213 Endometrial cancer
123807983 (SOS2)
05224 Breast cancer
123807983 (SOS2)
05223 Non-small cell lung cancer
123807983 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
123807983 (SOS2)
05160 Hepatitis C
123807983 (SOS2)
05163 Human cytomegalovirus infection
123807983 (SOS2)
05165 Human papillomavirus infection
123807983 (SOS2)
09165 Substance dependence
05034 Alcoholism
123807983 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123807983 (SOS2)
01522 Endocrine resistance
123807983 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
IQ_SEC7_PH
RHG20_PH
PH_19
Motif
Other DBs
NCBI-GeneID:
123807983
NCBI-ProteinID:
XP_045678086
LinkDB
All DBs
Position
Unknown
AA seq
1332 aa
AA seq
DB search
MQHAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDKKLFKSSDI
EKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVAQYFQSIADGFREAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFIMRKTQICDKEDSCEYKHAFELISKDENSVIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLPSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
AEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISKPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEIRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPNSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNMKSDDDPPAIPPRQPPPPKIKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDSPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDISTCPNSPN
TPPSTPSPRVPRRCYVLNSSHSNVVHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcatgcgccgcagccctacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgttggtctcggccctgaggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagaatctctctattacattgaagagctgatttttcagctacttaataaattatgc
atggcccaaccaaggactgttcaagatgtagaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctatagctgatgcacagtcggccatagagaaacgaaaacgaaga
aatcctctcttattgcctgtggacaaaatccatccttcactgaaggaagttttagggtac
aaagtggactaccatgtgtccttatatattgtggctgtactagagtatatctcagctgat
attttgaaattagctggtaattatgtttttaatattcgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgaacctagttcttcaggtgaattaaactattac
gatcttgtcagaactgaaattgcagaagaaagacagtatctgcgggaactaaatatgatc
ataaaagtgttccgagaagcctttctttctgacaaaaagctgttcaaatcttctgacatt
gaaaagattttcagtaatatttcagatatacatgaattgacagtaaaacttttagggttg
attgaagacacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggacatt
ctttcaccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcaa
tactttcagtccattgctgatggttttagagaggcagttcgttatgtccttccacgcctt
atgctggtgccagtgtatcactgttggcactattttgaattgttaaagcaattgaaagca
tgtagtgaagaacaagaggacagagaatgtttaaatcaagcaattactgctctcatgaat
ctccaaggtagtatggaccgaatttacaagcaatattcacctcgacgccgacctggggat
cctgtctgccctttttataaccgtcagttaagaagcaagcatttggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaatttattatggaaggtccattgacaagaattggtgctaaacatgaacggcatattttc
ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcacgccttccaggt
tatagtagtgcagaatacagattaaaagaaaaattcatcatgagaaaaacacaaatatgt
gataaagaagatagttgtgagtacaaacatgcatttgaattgatatccaaagacgaaaac
agcgtaatatttgctgctaagtctgcagaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatcgaatgttagattcagttttattgaaagaagaa
aatgagcaaccactgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgccaagtagaagtggaatccccattattaaa
ggaggaacggtggtgaagttaattgaaagactgacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaacttctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gcagagaaaggcgaacaaccaattagtgcagaccttaaaagatttcgcaaggaatatgtc
caaccagtacaacttaggatcctaaatgtatttcggcactgggttgaacaccatttctat
gactttgaaagagatttggagttgcttgaaaggctagaatccttcatttcaagtgtaaga
gggaaagccatgaagaaatgggtagagtccattgctaagatcatcaagagaaagaaacaa
gctcaggcaaatggaataagtcataatattacctttgaaagtccccctccaccaattgaa
tggcatatcagcaaaccaggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagttcaaccctct
gaacttgtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgtcatactacaaatcttacactttggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtagcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca
gtatacagactagatcatacctttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaggatcactttaaaaaatacctagcaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtggctgaaattactggagaaattcagcaatatcagaatcaaccttactgtttacgg
atagaaccagaaataaggcggttctttgaaaaccttaatcccatgggaagtgcttctgaa
aaagagtttacggattacttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcccaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggcactttaagaggtcatccaacaccattagaa
agagaaccatgtaaaataagctttagtcggattgctgaaaccgagcttgaatcaacagtg
tcggcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaatagttcctgtggcagcaatagcatctttgctcca
gttctcttgccaaattcaaaatctttcttcagttcgtgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatatgaaatctgatgatgaccctcctgctattccaccaagacaacct
cctcctccaaagataaaacccagagttcctgctcctactggtgcatttgatgggccactg
catagtccaccaccgccgccgccaagagatcctcttcctgatagccctccaccagttccc
cttcggcctccggaacactttataaactgtccatttaatcttcaaccgcctccactggga
catcttcacagagacccagactggttcagagacattagcacttgtccaaattcgccaaac
actcctcctagcacaccctctccaagggtaccacgtcgatgctatgtgctcaattctagt
cacagtaatgttgttcatccccaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttataaacgggagctttcacaccccccattgtat
agactgcctttgctagaaaacgcagaaactcctcaatga
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integrated database retrieval system
