KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123809430
Entry
123809430         CDS       T07912                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X1
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas04010  MAPK signaling pathway
phas04015  Rap1 signaling pathway
phas04218  Cellular senescence
phas04620  Toll-like receptor signaling pathway
phas04664  Fc epsilon RI signaling pathway
phas04668  TNF signaling pathway
phas04714  Thermogenesis
phas04750  Inflammatory mediator regulation of TRP channels
phas04912  GnRH signaling pathway
phas04935  Growth hormone synthesis, secretion and action
phas04936  Alcoholic liver disease
phas05014  Amyotrophic lateral sclerosis
phas05022  Pathways of neurodegeneration - multiple diseases
phas05132  Salmonella infection
phas05135  Yersinia infection
phas05145  Toxoplasmosis
phas05161  Hepatitis B
phas05169  Epstein-Barr virus infection
phas05170  Human immunodeficiency virus 1 infection
phas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
phas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123809430 (MAP2K3)
   04015 Rap1 signaling pathway
    123809430 (MAP2K3)
   04668 TNF signaling pathway
    123809430 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    123809430 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123809430 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    123809430 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123809430 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    123809430 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123809430 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    123809430 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123809430 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123809430 (MAP2K3)
   05161 Hepatitis B
    123809430 (MAP2K3)
   05169 Epstein-Barr virus infection
    123809430 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123809430 (MAP2K3)
   05135 Yersinia infection
    123809430 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123809430 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123809430 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    123809430 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123809430 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123809430 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:phas01001]
    123809430 (MAP2K3)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     123809430 (MAP2K3)
Protein kinases [BR:phas01001]
 Serine/threonine kinases: STE group
  STE7 family
   123809430 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH
Other DBs
NCBI-GeneID: 123809430
NCBI-ProteinID: XP_045680570
LinkDB
Position
Unknown
AA seq 347 aa
MESPASSQPAGIPQSKGKSKRKKDLHISCVSKPFMPNPTPPRNLDSRAFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHTQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMMIPEDILGKIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILQFPYGSWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggaatcccccgcctccagccaacctgctggcataccccagtccaaaggaaaatccaag
aggaagaaggacttacatatatcctgtgtgtccaagccgttcatgcccaaccccaccccc
cccaggaaccttgactcccgggccttcatcaccattggagacaggaactttgaggtagag
gctgatgacctggtgacgatctcagagctggggcgcggagcctatggcgtggtggagaaa
gtacggcacacccagagcggcaccatcatggctgttaagcggatccgggccaccgtgaac
tcccaggagcagaagcgtctgcttatggacttggatgtgaacatgcgcacggttgactgc
ttctacactgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gaactcatggacacatccctggacaagttctaccgtaaagtgcttgataaaaacatgatg
attccagaggacattctggggaagattgctgtgtctattgtgagggcgctggagcacctg
catagcaagctgtccgtgattcacagagatgtaaagccatctaatgtcctcatcaacaag
gaggggcacgtgaagatgtgtgactttgggatcagcggctacttggtagattctgtggcc
aagacgttggatgccggctgtaagccctacatggctccggagagaatcaacccagaactg
aaccagaagggctacaacgttaagtctgacgtctggagcctcggcattaccatgatcgag
atggctatcttacagtttccttatgggtcctgggggaccccattccagcagctgaagcag
gtggtggaggagccgtctccccagctccccgctgaccgtttttctcctgagtttgtggac
ttcactgcacaatgcctgaggaagaaccctgccgaacgcatgagctacctggagttgatg
gagcatcctttcttcactttgcacaaaaccaagaagacagacatcgctgcttttgtgaag
gagatcctaggagaggactcatag

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