Phyllostomus hastatus (greater spear-nosed bat): 123809613
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Entry
123809613 CDS
T07912
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00230
Purine metabolism
phas01100
Metabolic pathways
phas04927
Cortisol synthesis and secretion
phas04934
Cushing syndrome
phas05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123809613 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
123809613 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
123809613 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123809613 (PDE8A)
Enzymes [BR:
phas01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
123809613 (PDE8A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PDE8
PAS_4
PAS_3
PAS_8
DUF5894
Response_reg
Motif
Other DBs
NCBI-GeneID:
123809613
NCBI-ProteinID:
XP_045680759
LinkDB
All DBs
Position
Unknown
AA seq
828 aa
AA seq
DB search
MGCAPSIHVSESRSAYGGGKEAADAPGPAGPRLPHDPETTASPATGGPGLAASGPRGGGS
NTATTEVQFGPMKFHPDQLQVLLVFTKEDNQCHGFCKACEKAGFKCTVTKEAHSVMACFL
AKHHDIIIIDHRNPRQLDAEALCRSIRSSKVSENTVIIGVVRRAEREEPSVLPLIAAGFT
RRYVENPSLMACYNELLQLEFGEVRSQLKLRACNSVFTALEKSQEAIEIISEDHIIQYAN
PAFETTMGYKSGDLIGKELAEVPINEKKADLLDTINSCVKTGKEWQGVYYARNGDNMQQN
VKIVPVIGQGGKIRHYVSIIRVCSGNNKAEKIAECVQSDTHTDSQLGKHKDKRKSSLDVR
SVASRTNELASQRRHSSMARIHSMTIEAPITKVINIINAAQENSPTPVTEALDRVLEILR
TTELYSPQLGVKDDDPHASDLVGGLMSDGLRKLSGNEYVLSTKGLPHISSSIVTPVTLHD
VPPRIARAIENEDYWDFDIFELEAATQKRPLIYLSLKIFTRFGICEFLNCSETTLRSWLQ
VIEANYHSSNPYHNSTHAADVLHATAYFLCRERIKQTLDPLDEAAALIAATIHDVDHPGR
TNSFLCNAGSELAVLYNDLAVLESHHAALAFQLTAGDDKCNIFKNMERNDYRTLRQAIID
MVLATEMTKHFEHVNKFINSVNKPLAALEESEKTEEDQEAINTALRTPENRALIKRMLIK
CADVSNPCRPLDQCIEWAARISEEYFCQTDEEKQQNLPVVMPVFDRNTCSIPKSQISFID
YFITGMFDAWDAFVDLPELLQHLDNNFKYWKGLDEMKLRSIRPPPEPE
NT seq
2487 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgccccgagcatccacgtttccgagagccggtcggcgtacggcggcggcaag
gaggccgcggacgcgcccggccccgccgggccgcgcctccctcacgacccggagaccacc
gcctcgcccgcgaccggcggccccggcctcgcggcgtccgggccgcgcggcggcggcagc
aacacggcgaccactgaagtgcaatttggccccatgaaatttcatccagatcaactccag
gtacttttagtgtttaccaaagaggacaaccagtgtcacgggttctgtaaggcgtgtgaa
aaagcagggtttaagtgcacggtcaccaaggaggcccactccgtcatggcctgtttcctg
gccaaacaccacgacatcatcatcatcgaccaccgaaatccccggcagctggacgcagag
gcgctgtgcaggtctattagatcctcaaaagtctcggaaaacacagttattattggcgta
gtacgcagggcggagagggaagagccgtccgtgctgcccctcatcgctgccggcttcacc
aggaggtacgtggagaacccgagcctcatggcctgctacaacgagctgctgcagctggag
ttcggagaggtgcgctcgcagctgaaactcagggcttgtaactcagtattcacggcatta
gagaaaagtcaagaagcaattgaaattataagtgaagaccacattatacagtatgcaaat
cctgcatttgaaacaacaatgggctataaatcaggtgacctaatagggaaggagttagca
gaagtgcctataaatgaaaaaaaggcggacttgctcgacactataaattcgtgtgtcaag
acggggaaggagtggcaaggagtttactacgccagaaacggggacaacatgcagcagaac
gtgaagatagtgcctgtcattgggcaggggggaaaaattagacactatgtgtccattatc
agagtgtgcagtggcaacaacaaggctgagaaaatagctgaatgtgttcagtctgacact
cacacagacagccagctgggcaagcacaaagacaagaggaagagctccctggacgtcaga
agtgtggcctcccgaacgaacgaactggccagccagaggcgacactcctccatggcccgg
atacactccatgaccatcgaggcgcccatcaccaaggtgatcaacattatcaacgctgcg
caggaaaacagccccacgcccgtgacagaagccctagaccgcgtgctggagattctgaga
accactgagctgtactcgccgcagctcggcgtcaaggacgacgacccccacgccagcgac
ctcgtggggggcctgatgtctgatggtttgcgaaagttatccgggaatgaatatgtcctt
tcaacaaaaggcctgccccacatttccagcagtatcgtcactcccgtcaccctgcacgac
gtgccgccgcggatagcgcgggccatagagaatgaggactactgggacttcgatattttc
gagctggaggctgccactcagaaaaggcctttgatttatctcagtctcaagatcttcact
cgttttggaatctgcgaattcttgaactgctccgagacaacgctgaggtcgtggctgcag
gtcatcgaagccaactaccactcctccaacccctaccacaactcgacgcacgccgccgac
gtgctgcacgccacggcctacttcctctgcagggagaggatcaagcaaactctagacccg
ctcgatgaggccgcagccctcattgcagccaccattcacgatgtggaccaccccgggagg
acgaactccttcctgtgcaacgcggggagcgagctggccgtcctgtacaatgacctcgcc
gtgctggagagccaccacgcggccttggccttccagctgactgctggagacgacaagtgc
aacatcttcaaaaacatggagaggaacgactatcggaccctgcgccaggctatcatcgac
atggtcttggccacggagatgacaaagcacttcgagcacgtcaacaagttcatcaacagc
gtcaacaagcccttggcggcactggaggagagcgagaaaactgaggaagatcaagaagcc
atcaacactgctctcaggaccccggagaaccgggctctgatcaagcggatgctgatcaag
tgcgctgacgtgtccaacccctgccggcccctggaccagtgcatcgagtgggctgcacgc
atctcggaagagtatttttgtcagaccgacgaagaaaagcagcagaacttacctgtagtg
atgccggtgtttgacagaaatacctgcagcatccccaagtcccagatctccttcatcgac
tacttcatcacaggcatgttcgatgcttgggacgccttcgtagacctgccagagttactg
cagcacctggacaacaacttcaaatactggaaaggactcgacgagatgaagctgcggagc
atccggccacccccggaaccagaatag
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