Phyllostomus hastatus (greater spear-nosed bat): 123809769
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Entry
123809769 CDS
T07912
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521
EGFR tyrosine kinase inhibitor resistance
phas01522
Endocrine resistance
phas04010
MAPK signaling pathway
phas04014
Ras signaling pathway
phas04015
Rap1 signaling pathway
phas04066
HIF-1 signaling pathway
phas04068
FoxO signaling pathway
phas04081
Hormone signaling
phas04114
Oocyte meiosis
phas04140
Autophagy - animal
phas04144
Endocytosis
phas04150
mTOR signaling pathway
phas04151
PI3K-Akt signaling pathway
phas04152
AMPK signaling pathway
phas04211
Longevity regulating pathway
phas04213
Longevity regulating pathway - multiple species
phas04510
Focal adhesion
phas04520
Adherens junction
phas04550
Signaling pathways regulating pluripotency of stem cells
phas04730
Long-term depression
phas04913
Ovarian steroidogenesis
phas04914
Progesterone-mediated oocyte maturation
phas05200
Pathways in cancer
phas05202
Transcriptional misregulation in cancer
phas05205
Proteoglycans in cancer
phas05214
Glioma
phas05215
Prostate cancer
phas05218
Melanoma
phas05224
Breast cancer
phas05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123809769 (IGF1R)
04014 Ras signaling pathway
123809769 (IGF1R)
04015 Rap1 signaling pathway
123809769 (IGF1R)
04066 HIF-1 signaling pathway
123809769 (IGF1R)
04068 FoxO signaling pathway
123809769 (IGF1R)
04151 PI3K-Akt signaling pathway
123809769 (IGF1R)
04152 AMPK signaling pathway
123809769 (IGF1R)
04150 mTOR signaling pathway
123809769 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
123809769 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123809769 (IGF1R)
04140 Autophagy - animal
123809769 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
123809769 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123809769 (IGF1R)
04520 Adherens junction
123809769 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
123809769 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
123809769 (IGF1R)
04914 Progesterone-mediated oocyte maturation
123809769 (IGF1R)
09156 Nervous system
04730 Long-term depression
123809769 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
123809769 (IGF1R)
04213 Longevity regulating pathway - multiple species
123809769 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123809769 (IGF1R)
05202 Transcriptional misregulation in cancer
123809769 (IGF1R)
05205 Proteoglycans in cancer
123809769 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
123809769 (IGF1R)
05214 Glioma
123809769 (IGF1R)
05218 Melanoma
123809769 (IGF1R)
05215 Prostate cancer
123809769 (IGF1R)
05224 Breast cancer
123809769 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123809769 (IGF1R)
01522 Endocrine resistance
123809769 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123809769 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
phas04090
]
123809769 (IGF1R)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123809769 (IGF1R)
Protein kinases [BR:
phas01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
123809769 (IGF1R)
CD molecules [BR:
phas04090
]
Proteins
123809769 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
123809769
NCBI-ProteinID:
XP_045681009
LinkDB
All DBs
Position
Unknown
AA seq
1368 aa
AA seq
DB search
MKSGSGGGSLTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLRRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAASNNYIVGNKPPKECGD
LCPGTVEEKPLCEKTTINNEYNYRCWTTHHCQKTCPSACGKRACTENSECCHPECLGSCS
APDDDAACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANILNAESSDTEGFVIHD
GECMQECPSGFIRNGTQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTNTWKNRIIVTWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPSNKDMEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQDSYLYRH
NYCSKADKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERKRRDLAQIANTTMSSRIRNSTMPDTYNVTELEEPETEYPFFE
ARVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVPRQEYRKHGGARLNRLNPG
NYTARIQATSLSGNGSWTEPVFFYVQAKTTYENFIHLIIALPVAALLIVGGLVIMLYVFH
RKRNSNRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEIENNPAFHPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAAR
NCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFG
VVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF
LEIIGSIKDELEPGFQEVSFYYSDENKPPDTEELDLEPDIMESVPLDPSASACSLPLPDR
YSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERPLPLPQSSTC
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgaagtccggctccggaggagggtccctgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcggccccggcatcgacatccgc
aatgactaccagcagctgcggcgcctggagaactgcacggtgatcgagggctacctgcac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggggacctcttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatcgggctgtacaacctgcggaacatcacccggggggcc
atccggatcgagaagaacgccgacctctgctacctgtccacggtggactggtccctcatc
ctggacgcggcctccaacaactacatcgtgggcaacaagcccccgaaggagtgcggggac
ctgtgtccggggacggtggaggagaagcccctgtgcgagaagaccaccatcaacaacgag
tacaactaccggtgctggaccacccaccactgccagaaaacgtgcccgagcgcgtgcggg
aagcgggcctgcacggagaacagcgagtgctgccacccggagtgcctgggcagctgcagc
gcgcccgacgacgacgcggcctgcgtggcctgccgccactactactacgccggcgtctgc
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatcctcaacgccgagagcagcgacaccgagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcacccagagcatgtac
tgcatcccctgcgaaggcccttgccccaaggtctgtgaggaagaaaagaagacgaagacc
atcgactcggtgacgtccgcgcagatgctccaaggctgcaccatcttcaagggcaatttg
ctcattaacatccgacggggcaataacattgcctcggagctggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccactcccacgccttggtctccttgtcc
ttcctcaagaaccttcgcctgatcttaggagaggagcagctcgaggggaactactccttc
tacgtcctcgacaaccagaacctgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaggcgggcaagatgtacttcgccttcaaccccaagctgtgcgtctccgaaatctac
cgcatggaggaggtgacggggaccaaagggcgccagagcaaaggggacataaacaccagg
aacaacggagagagggcctcctgtgagagcgacgtgctgcacttcacctccaccaacacg
tggaagaaccgcatcatcgtcacgtggcaccggtaccggcccccggactaccgggacctc
atcagcttcaccgtctactacaaggaagcgcccttcaaaaacgtgacggagtacgacggc
caggacgcctgcggctccaacagctggaacatggtggacgtggacctgccctccaacaag
gacatggagccgggcatcctgctgcacgggctgaagccctggacgcagtacgcggtgtac
gtgaaggccgtgaccctcaccatggtggagaacgaccacatccgcggggccaagagcgag
atcctgtacatccgcaccaacgcctcagttccttccatccccctggacgttctctcggcg
tccaactcctcctcgcagctgatcgtgaagtggaacccgccgtcgctgcccaacggcaac
ctgagctactacatcgtccggtggcagcagcagccccaggacagctacctgtaccggcac
aattactgctccaaagcagacaaaatccccatccggaagtacgccgacggcaccatcgac
atcgaggaggtgacggagaaccccaagaccgaggtgtgcgggggcgagaaggggccgtgc
tgcgcctgccccaagaccgaggcggagaagcaggccgagaaggaggaggccgagtaccgc
aaggtcttcgagaacttcctgcacaactccatcttcgtgcccagacccgagaggaagcgg
agggacctcgcgcaaattgccaacaccaccatgtccagccggatccgaaacagcacgatg
ccggacacctacaacgtcacagagctggaggagccggagacggagtacccgttcttcgag
gccagagtggacaacaaggagaggacggtcatttccaacctgcggcctttcaccctgtac
cgcatcgacatccacagctgcaaccacgaggccgagaagctgggctgcagcgcctccaac
tttgtctttgcgaggaccatgcctgcagaaggagcagacgacattcccgggccggtgacc
tgggagccgaggcctgagaactccatcttcctgaagtggccggaacccgagaatcccaat
gggctgatcctgatgtacgagataaaatacggctcgcaggtcgaggatcagcgggagtgc
gtgcccaggcaggagtacaggaagcacggaggggccaggctgaaccggctcaacccgggg
aactacacggcccggatccaggccacctctctgtctggcaacggctcgtggacggagccc
gtgttcttctacgtccaggccaaaacgacatacgagaacttcatccacctcatcatcgcg
ctgccggtcgccgcgctgctcatcgtgggagggctggtgatcatgctgtacgtcttccac
aggaagcggaacagcaacaggctggggaatggcgttctgtacgcttccgtgaacccagaa
tatttcagcgcggcggacgtgtacgtgcccgacgagtgggaggtggcccgtgagaagatc
accatgagccgggagctgggccagggctccttcgggatggtgtacgagggggtcgccaag
ggcgtggtcaaggatgagcccgagacccgggtggccatcaagaccgtcaacgaggccgcg
agcatgcgcgagcgcatcgagttcctcaacgaggcttcggtgatgaaggagttcaactgc
caccacgtggtgcgtttgctgggcgtggtgtcgcagggccagccgacgctggtcatcatg
gagctcatgactcggggcgatctcaaaagctatctcaggtctctgcggccggaaatagag
aataacccagccttccatcccccgagcctcagcaagatgatccagatggccggggagatt
gcagacggcatggcgtacctcaacgccaacaagttcgtgcaccgagacctcgctgcccgg
aactgcatggtggccgaagacttcacggtcaagatcggagatttcggcatgacgagagac
atctacgagactgactattaccggaaaggagggaagggccttctgcccgtgcgctggatg
tcccccgagtccctcaaggatggcgtgttcaccactcactccgacgtctggtccttcggg
gttgtcctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaacgag
caagtcctgcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgac
atgctgtttgagctcatgcgcatgtgctggcagtacaaccccaagatgaggccctccttc
ctggagatcatcggcagcattaaagacgagttggagcccggcttccaggaggtgtccttc
tactatagcgacgagaacaagccgcccgacaccgaggagctggacctggagccggacatc
atggagagcgtgccgctggacccctcggcctccgcgtgctccctgccgctgcccgacaga
tactcaggacacaaggccgagaacggcccgggccccggcgtgctggtgctgcgggccagc
ttcgacgagaggcagccttacgcgcacatgaacggcggccgcaagaacgagaggcccctg
cccctgccccagtcgtccacctgctga
DBGET
integrated database retrieval system
