| Entry |
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| Symbol |
PDE3B
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| Name |
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase B
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| KO |
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| Organism |
phas Phyllostomus hastatus (greater spear-nosed bat)
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| Pathway |
| phas04914 | Progesterone-mediated oocyte maturation |
| phas04923 | Regulation of lipolysis in adipocytes |
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| Brite |
KEGG Orthology (KO) [BR:phas00001]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123810006 (PDE3B)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
123810006 (PDE3B)
04024 cAMP signaling pathway
123810006 (PDE3B)
04022 cGMP-PKG signaling pathway
123810006 (PDE3B)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123810006 (PDE3B)
04922 Glucagon signaling pathway
123810006 (PDE3B)
04923 Regulation of lipolysis in adipocytes
123810006 (PDE3B)
04914 Progesterone-mediated oocyte maturation
123810006 (PDE3B)
04924 Renin secretion
123810006 (PDE3B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
123810006 (PDE3B)
Enzymes [BR:phas01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
123810006 (PDE3B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1120 aa
MRRDERDSKAMRYPQPPDGAGLPPESMRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELL
LPPASPQQPRRSPFTGARLALGALAAFVLALLLGSWTESWAARAARLWTLLRVCSLSLSP
LFSIACAFFFLTCFLTRTKRGPNAGWSSAGGSWWLLALPACCYLGDFLVWQWWSWTCGDE
DIGALAPHTPPAATGRLFLVLSCVGLLTLAHRVRLQHSILVLLFSSSVWWVSATSLGSLP
SALRPLLACLVGGAGCLLALGLDNFFQIREAPHHPRLSSTAEEKVPVIRPRRRSSCVSFG
ETSASYYGSCKMFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGSGVDLSVLNEARN
MVSDLLTDPTLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPADRGD
RKLHKGLNSRNSLPTPQLRRSSGTSSLPPIETSASRWERSNGKRPHQEFGISSQGCYLNG
PFSSNLLTTPKQRSSSVSQTHHIGLRRAGVLPSLSPVNSPGHGPVSAGSLANRSPIEFPG
TADFLAKPSVILHRSLGNAPTSPDFYQQLKNSGSNLCNSCGHQILKYVSTSESVSGTDCH
NGKSGDEDNTIFSKESLNLTEAQQEVETEKRDSRKLFLEGDNHLTEEAQNEQQSNIEQAA
SQDLILIEDYDSLIEKMSNWNFQIFELVEEMGEKSGKILSQVMYTLFQDTGLLEVFKIPT
LQFMNYFCALENGYRDIPYHNRIHATDVLHAVWYLTTRPIPGLQQIHSNHGTGSETESDG
RINPGQIAYISSRSCSIPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATN
APQAVLYNDRSVLENHHAASAWNLYLSSPDYNFLLNLDHMEFKRFRFLVIEAILATDLKK
HFDFLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRNLHLKWTEGIVN
EFYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIEAE
EDDDTESCYDEDGEELDTDDEEIEDNLNLKPQRRKGRRQIFCQLMHHLTENHKIWKEIIE
EEEKCKTDGNKVQVENSSLPQADEIQVIEEADEEEERQFE |
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| NT seq |
3363 nt +upstreamnt +downstreamnt
atgaggagggacgagcgagactccaaagccatgcggtacccgcagccgccggacggggcc
ggcttaccccctgagagtatgaggaacggctacgtgaagagctgcgtgagccccttgcgg
caggacccaccgcgcggcttcttcttccacctctgccgcttctgcaacgtggagctgctg
ctgccgccagcctccccccagcagccgcggcgctcccccttcaccggggcgcgcctcgcg
ctgggcgccctagctgcctttgtcctcgccctactgctcggctcgtggaccgagagctgg
gctgccagggctgccaggctgtggaccctgctgcgtgtctgctccctcagcctcagcccc
ctcttcagcatcgcctgtgccttcttcttcctcacctgcttcctgacccggaccaagcgg
ggccccaacgccggctggagcagcgccggcggctcctggtggttgctggcgctgcccgca
tgctgttacctgggggacttcttggtgtggcagtggtggtcttggacttgcggggacgaa
gacataggggctctggccccgcacacgcccccggcggcgacgggcaggttgtttttggtg
ctgagctgtgtgggcttgctgacgctcgcgcaccgggtgaggctgcagcacagcatcctg
gtgctgctcttctccagctcggtctggtgggtctcggccactagcctcgggtcgctgccc
tcagccctgcggcccctgctggcttgcctggtcgggggcgctggctgcctcttggccctg
gggttggataacttttttcaaatcagggaagctcctcatcatcctcggttgtccagtacc
gcggaagaaaaagtgcctgtgattagaccccgcaggaggtccagctgtgtttcattcgga
gaaacttcggccagttactatggaagttgcaaaatgttcaggagaccttcgttgccttgc
atttccagagaacagatgattctttgggattgggacttaaagcagtggtataaacctcat
taccagaattctggaggtggaagtggagttgatctttcagtgctaaatgaggctcgcaat
atggtgtcagatcttctaactgatccaaccctccccccacaagtcatttcttccctgcgg
agtatcagcagtttgatgggtgctttctcaggttcctgcaggccaaagattaaccctctc
acaccatttcctggattttacccctgttctgaaatagaagacccagctgacagaggagat
cgaaaacttcacaagggactgaacagcaggaacagtttgccaactccgcagctgaggagg
agctcaggaacttcaagtctgccacctattgaaacttctgcttcacggtgggaacgcagt
aatggcaaaaggcctcaccaagaatttggcatttcaagtcaaggatgctatctaaatggg
ccttttagttcaaatcttctgacaaccccgaagcaaaggtcatcttctgtatcgcaaact
caccatataggtctaagaagagctggtgttttacccagcctgagtcctgtgaattctcct
ggccatggaccagtgtctgctggctctttagctaatcgatcacctatagaatttcctggt
accgctgattttcttgctaagccaagtgttattttacacagatctctgggcaatgcaccc
acctcaccagatttttatcagcaacttaaaaattctggtagtaatttatgtaacagctgc
ggacatcaaatactgaaatatgtttcaacgtctgaatcagtgtctggtacagactgccac
aatggaaaatcaggtgatgaagacaataccattttctcaaaagaatcactcaaccttaca
gaagctcaacaagaagtggaaacagagaaaagagactccagaaaattatttttggaaggt
gataatcacctcacagaagaggcacagaatgaacagcaatcaaatattgaacaggcagca
tcacaggacctgattttaatagaagactatgattcattaatagaaaagatgagcaactgg
aattttcaaatttttgaacttgtagaagagatgggagagaaatcaggaaagatccttagt
caggttatgtataccttatttcaagatactggtttattggaagtatttaaaattcccact
ctacaattcatgaactatttttgtgcattagaaaatggctatcgagatattccttatcac
aatcgtatacatgccactgatgtcctgcatgcagtttggtatctgacgacacggccgatt
cctggcttgcagcagatccacagtaatcacggaacaggaagtgaaacagagtctgatggt
agaattaaccctgggcaaattgcttacatttcttcgaggagctgctcaatcccagatgag
agctatggatgcctgtcttcaaacattcctgctttggaattgatggctttatatgtggca
gctgctatgcatgattatgatcacccagggcggacaaatgcatttctggtggctacaaat
gcccctcaggcagttttatacaacgacagatctgttctggaaaatcatcatgctgcatcg
gcttggaatctgtatctttccagcccagattacaacttccttcttaatcttgatcatatg
gaattcaagcgttttcgttttttagtcattgaagcaatccttgccacggatcttaaaaag
cattttgatttccttgccgaattcaatgccaaggccaatgatgtaaatagtaatggtata
gaatggagcaatgaaaatgatcgcctcttagtatgccaggtgtgcatcaaactggcagat
ataaatggcccagcaaaagttcggaacttgcatttgaaatggacagaaggcattgtaaat
gaattttatgagcagggagatgaagaagcaaatcttggtttgcccatcagtcccttcatg
gatcgttcttctcctcaactagcaaagctccaagagtcttttatcacccacatagtgggt
cccctctgtaactcctatgatgctgctggtctgctccccggtcagtggatagaagcagaa
gaggatgatgatactgaaagctgttacgatgaagatggtgaagaattagatacagacgat
gaagaaatagaagacaatctaaatcttaaaccacagagaaggaaaggcagacggcaaata
ttttgtcagctaatgcaccacctcactgaaaaccacaagatatggaaggaaatcatagag
gaagaagagaaatgtaaaactgatgggaataaagtgcaggtggagaactcttccttacct
caagcagatgagattcaggtcattgaagaagcagatgaagaggaagagagacagtttgaa
taa |
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