Phyllostomus hastatus (greater spear-nosed bat): 123811124
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Entry
123811124 CDS
T07912
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor isoform X1
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521
EGFR tyrosine kinase inhibitor resistance
phas01522
Endocrine resistance
phas03272
Virion - Hepatitis viruses
phas04010
MAPK signaling pathway
phas04012
ErbB signaling pathway
phas04014
Ras signaling pathway
phas04015
Rap1 signaling pathway
phas04020
Calcium signaling pathway
phas04066
HIF-1 signaling pathway
phas04068
FoxO signaling pathway
phas04072
Phospholipase D signaling pathway
phas04144
Endocytosis
phas04151
PI3K-Akt signaling pathway
phas04510
Focal adhesion
phas04520
Adherens junction
phas04540
Gap junction
phas04630
JAK-STAT signaling pathway
phas04810
Regulation of actin cytoskeleton
phas04912
GnRH signaling pathway
phas04915
Estrogen signaling pathway
phas04921
Oxytocin signaling pathway
phas04926
Relaxin signaling pathway
phas04928
Parathyroid hormone synthesis, secretion and action
phas04934
Cushing syndrome
phas05160
Hepatitis C
phas05163
Human cytomegalovirus infection
phas05165
Human papillomavirus infection
phas05171
Coronavirus disease - COVID-19
phas05200
Pathways in cancer
phas05205
Proteoglycans in cancer
phas05206
MicroRNAs in cancer
phas05207
Chemical carcinogenesis - receptor activation
phas05208
Chemical carcinogenesis - reactive oxygen species
phas05210
Colorectal cancer
phas05212
Pancreatic cancer
phas05213
Endometrial cancer
phas05214
Glioma
phas05215
Prostate cancer
phas05218
Melanoma
phas05219
Bladder cancer
phas05223
Non-small cell lung cancer
phas05224
Breast cancer
phas05225
Hepatocellular carcinoma
phas05226
Gastric cancer
phas05230
Central carbon metabolism in cancer
phas05231
Choline metabolism in cancer
phas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03272 Virion - Hepatitis viruses
123811124 (EGFR)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
123811124 (EGFR)
04015 Rap1 signaling pathway
123811124 (EGFR)
04630 JAK-STAT signaling pathway
123811124 (EGFR)
04066 HIF-1 signaling pathway
123811124 (EGFR)
04068 FoxO signaling pathway
123811124 (EGFR)
04072 Phospholipase D signaling pathway
123811124 (EGFR)
04151 PI3K-Akt signaling pathway
123811124 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123811124 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04915 Estrogen signaling pathway
123811124 (EGFR)
04921 Oxytocin signaling pathway
123811124 (EGFR)
04926 Relaxin signaling pathway
123811124 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
123811124 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123811124 (EGFR)
05206 MicroRNAs in cancer
123811124 (EGFR)
05205 Proteoglycans in cancer
123811124 (EGFR)
05207 Chemical carcinogenesis - receptor activation
123811124 (EGFR)
05208 Chemical carcinogenesis - reactive oxygen species
123811124 (EGFR)
05230 Central carbon metabolism in cancer
123811124 (EGFR)
05231 Choline metabolism in cancer
123811124 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123811124 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
123811124 (EGFR)
05212 Pancreatic cancer
123811124 (EGFR)
05225 Hepatocellular carcinoma
123811124 (EGFR)
05226 Gastric cancer
123811124 (EGFR)
05214 Glioma
123811124 (EGFR)
05218 Melanoma
123811124 (EGFR)
05219 Bladder cancer
123811124 (EGFR)
05215 Prostate cancer
123811124 (EGFR)
05213 Endometrial cancer
123811124 (EGFR)
05224 Breast cancer
123811124 (EGFR)
05223 Non-small cell lung cancer
123811124 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
123811124 (EGFR)
05171 Coronavirus disease - COVID-19
123811124 (EGFR)
05163 Human cytomegalovirus infection
123811124 (EGFR)
05165 Human papillomavirus infection
123811124 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123811124 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123811124 (EGFR)
01522 Endocrine resistance
123811124 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123811124 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
phas04147
]
123811124 (EGFR)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123811124 (EGFR)
Protein kinases [BR:
phas01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
123811124 (EGFR)
Exosome [BR:
phas04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
123811124 (EGFR)
Exosomal proteins of pancreatic cancer cells
123811124 (EGFR)
Exosomal proteins of bladder cancer cells
123811124 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
123811124
NCBI-ProteinID:
XP_045683045
LinkDB
All DBs
Position
Unknown
AA seq
1209 aa
AA seq
DB search
MRPSGTAGAALLVLLAAHFPAGLALEEKKVCQGTNNKLTQLGTLDDHFLSLQRMLNNCEV
VLGNLEITYMQRNYDLSFLKTIQEVAGYVLIALNVVEKIPLENLQIIRGNVLLENTHALS
VLSNYGPNRTGLRELPMRNLQEILHGAVRFSNNPSLCSVDTVQWQDIVDASFLGNMSTDF
QSNPSSSCPKCDLSCPNGSCWGAGKENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCASG
CTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQVDVNPDGKYSFGATCVKKCPRNY
VVTDHGSCVRACGSDSYEVEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSVNATNIKHF
RNCTSISGDLHILPVAFRGDSFTHTQPLDPKELDILKTVKEITGSLLIQAWPENRTDLHA
FENLEIIRGRTKQHGRFSFAVVGLNISSLGLRALKEVSDGDVVISGNRHLCYADTVNWKT
LFGTPGQKTKIEKNRDRRDCRAQGHVCNPLCSPEGCWGPGPRNCRSCRNVSRDKECVEKC
NILEGEPREFEENSECIRCHPECLPQPMNVTCTGHGPDRCVQCAHYVDGPHCVSACPSGV
LGENNTLVWKFADAQRVCHLCHPNCTYGCTGPGREGCPDRPKISSIATGIVGGLLLVLVV
ALGVGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDHPHACRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIHEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQ
QAFFHGTSPSRTPLLGSLSATSSSSTAACVDRNGQSCPLKEDSSLQRYSSDPTGALTEDI
INGTFLPAPEYINQLIPKRPAGSVQNPVYHNQPLNLAPGRDPHYQNPHSNAVGNPEYLNT
APPPAVNGVPDGPTLWGQKGGHQISLDNPDYQQDFFPREAKSNGIFKGPTAENADYLRAG
APSSESIGA
NT seq
3630 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccctccgggacggcgggagccgcgctcctggtgctgctggcggcgcacttcccg
gcggggctggcgctggaggaaaagaaagtttgccagggcaccaacaacaagctgacgcag
ctgggcacactggacgaccacttcctgagcctccagaggatgctgaacaactgcgaggtg
gtcctggggaacctggagatcacctacatgcagaggaactacgacctctccttcctgaag
accatccaggaggtggctggctacgtcctcatcgccctcaacgtggtggagaagatccct
ctggaaaacctgcagatcatcagggggaacgtgctcctggagaacacccacgccttgtcc
gtcttatccaactacgggcccaaccgcacggggctgcgggagctgcccatgcggaacctg
caggagatcctgcatggcgccgtgcgattcagcaacaaccccagcctctgcagcgtggac
accgtccagtggcaggacatcgtcgacgccagcttcctgggcaacatgtccacggacttt
cagagcaacccatccagcagctgccccaagtgcgatctgagctgccccaacgggagctgc
tggggcgcggggaaggaaaactgccagaaactgaccaaaatcatctgcgcccagcagtgt
tcggggcgctgccggggcaagtcccccagcgactgctgccacaaccagtgtgcgtccggc
tgcacggggccccgcgagagcgactgtctggtgtgccggaagttccgggacgaagccacg
tgcaaggacacctgcccgccgctcatgctgtacaaccccaccacgtaccaggtggacgtc
aacccggacgggaagtacagcttcggagccacctgtgtgaagaagtgtccccgcaactac
gtggtgaccgaccacgggtcgtgtgtgcgggcctgcggctccgacagctacgaggtggag
gaagacggcgtccgcaagtgtaaaaagtgcgaaggtccctgtcgcaaagtctgtaacgga
ataggcatcggagagttcaaggacaccctctccgtaaacgccacgaacatcaaacacttc
cggaactgcacgtccatcagcggcgacctccacatcctgccggtagcctttaggggcgac
tccttcacacacacgcagcctctggaccccaaggagctggacattctcaagaccgtcaag
gagatcacagggtctctgctgatccaggcctggccggagaacaggacggacctgcacgcg
ttcgagaacctggagatcatacgcggcaggaccaagcagcacggccgcttctccttcgcg
gtggtcgggctgaacatcagctccctggggctgcgcgcgctgaaggaggtcagcgacggc
gacgtggtgatctcggggaaccgccacctgtgctacgccgacacggtgaactggaagacg
ctcttcgggaccccgggccagaaaaccaagatcgagaagaaccgggaccggagagactgc
cgggctcaaggccacgtctgcaacccgctgtgctcgcccgagggctgctggggcccaggg
ccccggaactgcaggtcctgccggaacgtcagccgcgacaaggagtgcgtggagaaatgc
aacattctggagggcgagcccagggagttcgaggagaattccgagtgcatacggtgccat
cccgagtgcctgccgcagcccatgaacgtgacctgcacgggacacggcccggacaggtgt
gtgcagtgcgcccactacgtcgacggcccgcactgcgtcagcgcctgcccgtcgggggtc
ctgggcgagaacaacactctggtctggaagttcgcggacgcccagcgcgtatgccacctg
tgccacccgaactgcacctacggctgcacgggcccgggtcgggaaggctgcccagatagg
cccaagatctcatccatcgccacagggattgtgggcggcctcctcttggtgctggtggtg
gccctcggggtgggcctgtttatgcgcaggcgccacatcgtgcggaagcgcacgctgcga
aggctgctgcaggagcgcgagctcgtggagcccctcacgcccagcggagaagcgcccaac
caagctctcctgcggatcctaaaggagacagaattcaagaagatcaaggtgctgggctcg
ggcgccttcggcaccgtgtacaagggactctggatccccgagggcgagaaggtcaaaatc
cctgtggccatcaaggagttgagagaagccacgtctccgaaagccaacaaggagattctc
gacgaggcctacgtgatggccagcgtggaccacccccacgcgtgccgcctgctgggcatc
tgcctgacctccaccgtgcagctcatcacccagctcatgcccttcggctgcctgctggac
tacgtccgcgagcacaaggacaacatcggctcccagtacctgctcaactggtgtgtgcag
atcgccaagggcatgaactacctggaggaccggcgcctggtgcaccgggacctggcggcc
aggaatgtcctggtgaagacgccgcagcacgtcaagatcacggacttcgggctggccaag
ctgctgggcgcggaggagaaagagtaccacgcagagggaggcaaggtgcccatcaagtgg
atggctttggagtctatcttgcaccggatctatacccaccagagtgacgtctggagctac
ggggtgaccgtctgggagctgatgaccttcgggtccaagccgtacgacgggatcccggcg
agcgagatctcgaccgtgctggagaaaggagagcgcctcccgcagccgcccatctgcacc
atcgacgtctacatgatcatggtcaagtgctggatgatagacgcggacagccgccccaag
ttccgggagctgatccacgagttctccaagatggcccgcgacccccagcgctacctcgtc
atccagggcgatgagaggatgcacctgcccagccccacggactccaacttctaccgcgcg
ctgatggacgaggaggacatggaggacgtggtggacgcagacgagtacctcatcccccag
caggccttcttccacggcacctcgccctcgcgcacgcccctgctgggctccctgagtgcc
accagcagcagctccaccgcggcttgtgttgacaggaacgggcagagctgccccctgaag
gaagacagctccctgcagcggtacagctccgaccccaccggcgccctgaccgaggacatc
atcaacggcacgttcctcccggcgccagaatacataaaccagctgatccccaaacggccg
gcgggctccgtccagaaccccgtctaccacaaccagcccctcaacctggctccgggccga
gacccccactaccagaacccccacagcaacgccgtgggcaaccccgagtatctcaacacc
gcccctccccccgccgtcaacggcgtccccgacggccccaccctctgggggcagaaaggc
ggccaccaaatcagcctggacaaccccgactaccagcaggacttcttccccagggaagcc
aagtccaacggcatctttaaggggccgacggcggaaaatgcggactacctgagggcaggc
gccccgagcagtgagtccattggggcatga
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integrated database retrieval system
