KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123811692
Entry
123811692         CDS       T07912                                 
Symbol
GCK
Name
(RefSeq) hexokinase-4
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00010  Glycolysis / Gluconeogenesis
phas00052  Galactose metabolism
phas00500  Starch and sucrose metabolism
phas00520  Amino sugar and nucleotide sugar metabolism
phas00524  Neomycin, kanamycin and gentamicin biosynthesis
phas01100  Metabolic pathways
phas01200  Carbon metabolism
phas01250  Biosynthesis of nucleotide sugars
phas04910  Insulin signaling pathway
phas04911  Insulin secretion
phas04917  Prolactin signaling pathway
phas04922  Glucagon signaling pathway
phas04930  Type II diabetes mellitus
phas04950  Maturity onset diabetes of the young
phas05230  Central carbon metabolism in cancer
Module
phas_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
phas_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:phas00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    123811692 (GCK)
   00052 Galactose metabolism
    123811692 (GCK)
   00500 Starch and sucrose metabolism
    123811692 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    123811692 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    123811692 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    123811692 (GCK)
   04910 Insulin signaling pathway
    123811692 (GCK)
   04922 Glucagon signaling pathway
    123811692 (GCK)
   04917 Prolactin signaling pathway
    123811692 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    123811692 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    123811692 (GCK)
   04950 Maturity onset diabetes of the young
    123811692 (GCK)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     123811692 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 123811692
NCBI-ProteinID: XP_045684048
LinkDB
Position
Unknown
AA seq 458 aa
MESAMKEKAEQILAEFRLQEEDLKKVMRRMQKEMARGLRLETHEEASVKMLPTYVRSTPE
GSEVGDFLSLDLGGTNFRVMLVKVGKGEEGHWSVKTKHQMYCIPEDAMTGTAEMLFDYVS
ECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRD
AIKRRGDFEMDVVALVNDTVATMISCYYEDRQCEVGMIVGTGCNACYMEEMHNVELVEGE
EGRMCVNTEWGAFGDAGELDEFLLEYDRMVDESSLNPGQQLYEKLIGGKYMGELVRLVLL
KLVDENLLFRGEASEQLRTRGAFETRFVSQVESDSGDRKQIYNILRTLGLRPSATDCDIV
RRACESVSTRAAHMCAAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASV
RRLTPSCEITFIQSEDGSGRGAALVSAVACKKACMLGQ
NT seq 1377 nt   +upstreamnt  +downstreamnt
atggagagcgccatgaaggaaaaggcggagcagatcctggcggagttccggctgcaggag
gaggacctgaagaaggtgatgaggcggatgcagaaggagatggcccggggcctgcggctg
gagactcacgaggaggccagtgtgaagatgctgcccacctacgtgcgctccacacctgaa
ggctcagaagtcggggacttcctgtcgctggacctgggcggcaccaacttcagggtgatg
ctggtgaaggtgggcaagggtgaggagggccactggagcgtgaagaccaagcaccagatg
tactgcatccccgaggacgccatgacgggcacggctgagatgctcttcgactacgtctcc
gagtgcatctccgacttcctggacaagcatcagatgaagcacaagaagctgcccttgggt
ttcaccttctcctttcccgtgaggcacgaagacatcgacaagggcatcctgctcaactgg
accaagggcttcaaggcctcgggagcggaagggaacaacatcgtggggctcctgcgagac
gccatcaagcggaggggggactttgagatggacgtggtggcgctggtgaacgacacggtg
gccacgatgatctcctgctactacgaagaccgccagtgtgaggttggcatgattgtgggc
accggctgcaacgcctgctacatggaggaaatgcacaacgtggagctggtggaaggggag
gagggccgcatgtgcgtcaacaccgagtggggcgccttcggggacgcgggcgagctggac
gagttcctgctggagtacgaccgcatggtggacgagagctccctgaaccccggccagcag
ctgtacgagaagctcatcggcggcaagtacatgggtgagctggtgcggctcgtgctgctg
aagctggtggatgagaacctgctcttccgcggggaggcctcggagcagctgcgcacgcgc
ggagccttcgagacgcgctttgtgtcgcaggtggagagcgactctggcgaccgcaagcag
atctacaacatcctgcgcacgttggggctgaggccctcggccacggactgcgacatcgtg
cgccgcgcctgtgagagcgtgtccacgcgcgccgcgcacatgtgcgccgcggggctggca
ggcgtcatcaaccgcatgcgcgagagccgcagcgaggacgtcatgcgcatcaccgtgggc
gtggacggctcggtgtacaagctgcaccccagcttcaaggagcggttccacgccagcgtg
cgcaggctgacacccagctgcgagatcaccttcatccagtccgaggacggcagcggccgg
ggcgcggctctggtctctgcggtggcctgtaagaaggcctgcatgctgggccagtga

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