Phyllostomus hastatus (greater spear-nosed bat): 123813761
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Entry
123813761 CDS
T07912
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00310
Lysine degradation
phas01100
Metabolic pathways
phas05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
123813761 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
123813761 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
phas03036
]
123813761 (DOT1L)
Enzymes [BR:
phas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
123813761 (DOT1L)
Chromosome and associated proteins [BR:
phas03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
123813761 (DOT1L)
HMT complexes
Dot1-containing complex
123813761 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
123813761
NCBI-ProteinID:
XP_045686988
LinkDB
All DBs
Position
Unknown
AA seq
1732 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTAAPSPQDAYKSPQSPFYQLPPSVQRQPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDSASLHLRGKGGLGRELEAEPGRLHLELDCSKFSLPHFSSMSPELSMNGHVAGY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASVKASAGELHPRAEHTKENGLPYQSPGLTNGIKLSPQDPQPSSPMALQM
TGEKGSEKGLKERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRST
PSPVPQTRESSSTLEKQMGANGHGAGSNVAGSKGLALAPTAGFSYTGSVAISGALAGSPA
PLAAGAEPSAFDESSSSGSLFTTMSSRSSTPQHHQLLVQPRNSGPASPTHQLCVSPRLSA
AQGPLPDSSKGDLPPEAGFSDPENEAKRRIIFTISAGAGSAKQSPSNKHSPLPGGARGDS
NQSHGQDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNIN
QPLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEQ
GSTRIERKIATISLESKSPPKTLENGGSLIGRKPVPSSEPINSSKWKSTFSPIADLSLAK
AADSPLQASSALSQNSLFAFRPALEELGSVDAKLAAHPRKSFPGALSGAGGLSPVSNPPN
GFAFSGGLAADLSLHSFSDGASLSHKAPEATSLGAPLSFSAPRGKEGSTEPGPFVNKRQL
DVLGGPKGEGVKGREAEGGLPMCTPSDKALSHGKVGKGRDREPDFKNGHNLFISAAAVPT
GGLLSGPGLTTAVSSAGGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFS
SVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHAVPSSSTHPFGTSFGSGA
ACRSTTLSLTPMQAVASTPASSFQALSSVETRQPPPQPPLPMSRPPAGPPALHEPPPPNV
ALPPTPVMLPANSEPVVLQKLAPLPSNQAFLPASSAASLPSANASLSIKLASLPHKVSRP
SFMVHHQSLPGLALAQASPMIPQASSTGPSAMWVSLGMPPPYAARLAGVKPR
NT seq
5199 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccgtggccgctgccggtctacgacaaacaccatgatgctgctcatgaaatcattgagacc
atccgatgggtctgtgaggaaatcccagacctcaagcttgctatggagaattatgtccta
attgactacgacaccaaaagctttgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagttgtggaagggaaccacacaacctatgaagctcaacacg
cggccatccaacgggctcctgcggcacatcctgcagcaggtttacaaccactcagtgacg
gaccctgagaagctcaacaactacgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggtcgcgcagatgattgacgaaatcaagatgacagaggatgacctgttcgtg
gacctgggaagtggagtgggccaggtcgtgctgcaggtcgcggcagccaccaactgcaaa
catcactacggagtcgagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgatttcctctcggaggagtggagagagcggatcgccaatacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaatatg
aaggaaggtggcagaattgtgtcctcgaagccctttgctcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccattgaccgcacc
atacttgaaaactacttctctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgagaaaacaagagtaatacaaccacccccacgaaggtgcct
gagagcaaggcagctgtgcctgcagacacctctgtggattctggtgctgaggaagagaaa
gcagcgacaaccgctatcaagaagccgtccccctccaaagcacggaagaagaaactgaac
aagaagggacggaagctggctggccggaagcgtggacgtccgaagaagatgagcactgcg
aaccccgagcgtaagcccaagaagaaccctactgcactggacctgctgcacgcccagact
gtgtcccagacggccgcaccctcaccgcaggatgcgtacaagtcacctcaaagtccgttt
tatcagctacctcccagcgtgcagcggcagccccctgaccaactgctgctggcacccacc
ccacccgcactgcagaagctgctagagtccttcaagatccagtacctgcagttcctagca
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgctcggttgctgggggccgcacagcagctatttggccactgccaggcccagaaa
gaagaaataaagagactcttccagcagaaactggatgagttgggagtgaaggctctgacc
tacagtgacctgatccaagcacagaaggagatctcagctcacaaccagcagctccgagag
cagacagagcagctggagaaggacaacagggagctaaggagccagagcctgcagctgctg
aaggctcggtgtgaggaactgaagctggactggtccacactgtcgctggagaacctgctg
aaggagaagcaggccctgaagagccagatctctgaaaaacagaggcactgtctagagctg
cagataagcattgtggagctggaaaagagccagcggcagcaggaactcctgcagctcaag
tcctgcgtgccaccagacgactccgcatctttgcacctgcgagggaaaggtggcctgggc
cgggaactggaggcggagcctggtcggctgcaccttgagctagactgctctaagttctca
ctgccccatttcagtagcatgagcccagagctctccatgaatggccatgtggctggctat
gagctctgcaacacgctgagccggccctcatccaaacagaacaccccccagtacttggcc
tccccactggaccaggaggttgtgccctgtacccccagccatagcagccggccccggctt
gagaagctgtctggcttggccttgccagactacaccaggctctccccagccaagctggtg
ctgagacgccacctgagtcaggaccacacagccagtgtcaaggcatctgctggcgagctg
catccacgagctgagcacaccaaggagaatggccttccgtaccagagtccaggcctcacc
aacggcatcaagctgagccctcaggacccacagccctcatcccccatggccttacagatg
acaggagaaaagggcagtgagaagggtctgaaggagcgcacctacgccagcagtggtgag
gccatcaccagcctacctgtcagcatcccgctcagcactgtgcagcccagcaagctgcct
gtcagcatccccctggccagcgtggtattgcccagccgcgccgagaaggtgagaagcacc
cccagccctgtgcctcagacccgagagtcctcatccacacttgaaaagcagatgggtgct
aatggccatggtgctgggagcaacgttgctgggagcaaaggcctcgccctggcccccaca
gcaggtttctcctacactggctcagtggccatcagtggagccctggcaggcagcccagcc
ccgctcgctgctggagctgagccttctgccttcgatgagtcctccagttcggggagcctc
ttcactaccatgagctcccgcagctccaccccacagcaccatcaactgctagtgcagccc
cggaactctggtccggcctcaccgactcaccagctctgtgttagcccccggctgagtgct
gcccagggcccactccctgattccagcaaaggagaccttccccctgaggctggcttctca
gatccagagaacgaggccaagaggaggatcatcttcaccatctcagctggtgctggcagc
gccaagcagtcgccttctaacaagcacagccctctgccagggggcgcccgcggagatagc
aaccagagccatggacaggacagccgaaagcggggcaggaggaagcgggcatcagcgggg
actcccagcctgagctcgggtgtgtcccccaagcgccgggccttgccatctgtcgccggt
ctcttcacgcagtcttcagggtcccccctcaacctgaactccatggtcaacaacattaac
cagcctttggaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtt
ccttaccaggacaatgaccagccgcccgtgctcaagaaagagaagcccctgagccaaacc
aatggggcccactactccccactgacctccgacgaggagccgggctctgaggacgagcaa
ggcagcaccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccg
aaaaccttagaaaatggtggcagtctgataggaaggaagccggtgccctccagcgagccc
atcaacagcagcaagtggaagtccaccttctcgcccatcgccgacctcagcctggccaag
gctgccgacagcccactacaggccagctccgctctgagccagaactccctgttcgctttc
cggcccgccctagaggagcttggctcggttgatgccaagctggccgcccaccccaggaag
agcttcccgggtgcactgtcaggggctggcgggctgagtcccgtcagcaaccctcccaac
ggctttgccttcagcgggggcctggctgccgacctcagtttacacagcttcagtgatggt
gcttctctctcccacaaggcccctgaggcgaccagcctgggtgcccccctgagcttttcc
gcccctaggggcaaggagggcagcacagagcctggcccctttgtgaacaagaggcagctg
gatgtattgggtggcccaaaaggcgagggggtcaagggcagggaggcagaggggggcctg
cccatgtgcacaccctcagacaaggccttgtcgcatggcaaggtgggcaagggccgggac
cgtgagcccgacttcaagaatggccacaatctcttcatttccgccgctgccgtgcctact
gggggcctcctcagcggtccaggcctcaccacagcagtgtcctcagcaggcggcacagcc
ccctcctcccagacacaccggcccttcctgggcactttcgcacctggcccacagtttgcc
ttgggccccatgtccctgcaggccaacctaggctcgtctgtgctgcagtccttgttcagc
tctgtgccggctgccgctggcctagtgcacgtctcatcagctgcaacaagactgaccaac
tcgcatgccatgggcagcttttcctctggtgtggcaggcggtgcagttggaggtatcttt
aaccacgcggtgccttcctcctccactcatccgtttggaaccagtttcggcagcggggct
gcttgtcgcagcaccacgctgagcttaacccccatgcaggcggtggccagtacccccgcc
tcttcctttcaggccctgtcctctgtggagacgaggcagcccccaccccagcctcctctg
cccatgagtcgtccccctgcggggccaccagcactccacgagcccccccctcctaacgtc
gccttgcctcctactcccgtgatgctccctgctaactctgagcccgtggtcctacagaaa
cttgcgcccctcccgtctaaccaagctttcttacctgcttcctctgctgcctctctgcct
tctgctaacgcctctctgtccatcaagctcgcctccctcccacacaaggtctcccgcccc
tctttcatggtgcaccaccagtccctgccagggctggccctggcccaggcctcgcccatg
atcccgcaggccagctccacggggccatccgccatgtgggtttcccttggcatgccgcct
ccttatgccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
