KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123814829
Entry
123814829         CDS       T07912                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521  EGFR tyrosine kinase inhibitor resistance
phas01522  Endocrine resistance
phas04012  ErbB signaling pathway
phas04015  Rap1 signaling pathway
phas04062  Chemokine signaling pathway
phas04081  Hormone signaling
phas04137  Mitophagy - animal
phas04144  Endocytosis
phas04360  Axon guidance
phas04370  VEGF signaling pathway
phas04510  Focal adhesion
phas04520  Adherens junction
phas04530  Tight junction
phas04540  Gap junction
phas04611  Platelet activation
phas04613  Neutrophil extracellular trap formation
phas04625  C-type lectin receptor signaling pathway
phas04727  GABAergic synapse
phas04750  Inflammatory mediator regulation of TRP channels
phas04810  Regulation of actin cytoskeleton
phas04912  GnRH signaling pathway
phas04915  Estrogen signaling pathway
phas04917  Prolactin signaling pathway
phas04919  Thyroid hormone signaling pathway
phas04921  Oxytocin signaling pathway
phas04926  Relaxin signaling pathway
phas05100  Bacterial invasion of epithelial cells
phas05135  Yersinia infection
phas05152  Tuberculosis
phas05161  Hepatitis B
phas05163  Human cytomegalovirus infection
phas05167  Kaposi sarcoma-associated herpesvirus infection
phas05168  Herpes simplex virus 1 infection
phas05203  Viral carcinogenesis
phas05205  Proteoglycans in cancer
phas05207  Chemical carcinogenesis - receptor activation
phas05208  Chemical carcinogenesis - reactive oxygen species
phas05219  Bladder cancer
phas05417  Lipid and atherosclerosis
phas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    123814829 (SRC)
   04015 Rap1 signaling pathway
    123814829 (SRC)
   04370 VEGF signaling pathway
    123814829 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    123814829 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    123814829 (SRC)
   04137 Mitophagy - animal
    123814829 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123814829 (SRC)
   04520 Adherens junction
    123814829 (SRC)
   04530 Tight junction
    123814829 (SRC)
   04540 Gap junction
    123814829 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123814829 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123814829 (SRC)
   04613 Neutrophil extracellular trap formation
    123814829 (SRC)
   04625 C-type lectin receptor signaling pathway
    123814829 (SRC)
   04062 Chemokine signaling pathway
    123814829 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123814829 (SRC)
   04915 Estrogen signaling pathway
    123814829 (SRC)
   04917 Prolactin signaling pathway
    123814829 (SRC)
   04921 Oxytocin signaling pathway
    123814829 (SRC)
   04926 Relaxin signaling pathway
    123814829 (SRC)
   04919 Thyroid hormone signaling pathway
    123814829 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    123814829 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123814829 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    123814829 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123814829 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    123814829 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    123814829 (SRC)
   05203 Viral carcinogenesis
    123814829 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    123814829 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    123814829 (SRC)
   05168 Herpes simplex virus 1 infection
    123814829 (SRC)
   05163 Human cytomegalovirus infection
    123814829 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123814829 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    123814829 (SRC)
   05152 Tuberculosis
    123814829 (SRC)
   05100 Bacterial invasion of epithelial cells
    123814829 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123814829 (SRC)
   05418 Fluid shear stress and atherosclerosis
    123814829 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123814829 (SRC)
   01522 Endocrine resistance
    123814829 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:phas01001]
    123814829 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:phas04131]
    123814829 (SRC)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     123814829 (SRC)
Protein kinases [BR:phas01001]
 Non-receptor tyrosine kinases
  SRC family
   123814829 (SRC)
Membrane trafficking [BR:phas04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    123814829 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    123814829 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    123814829 (SRC)
  Macropinocytosis
   Kinases
    123814829 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 123814829
NCBI-ProteinID: XP_045688860
LinkDB
Position
Unknown
AA seq 543 aa
MGSNKSKPKDASQRRRSLEPAENTHGGGSGGAFPTSQTPSKPASADGHRGPNTAFSPAAA
EPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRK
VDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRG
TFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYY
SKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTT
RVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFL
KGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARL
IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNRE
VLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPG
ENL
NT seq 1632 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccagcgacgccgaagcctggagcct
gctgagaacacccatggtggtggcagtgggggtgccttccccacctcccagacccccagc
aagccggcctccgccgacggccaccgaggccccaacacggcgttctcccctgcggccgct
gagcccaagctgttcggcggcttcaactcctcagacacagtcacctccccgcagagggcg
gggcccctggctggtggagtgaccacctttgtggccctctatgactatgagtcccgcacg
gagaccgacctgtccttcaagaaaggggagcggctgcagatcgtcaacaacacgaggaag
gtggatgtcagagagggagactggtggctggcccactcgctcagcacgggacagacgggc
tacatccccagcaactacgtggcgccctccgactccatccaggctgaggagtggtacttt
ggcaaaatcacgagacgggagtcagaacggttactgcttaatgcagagaacccgaggggg
accttcctggtgcgagaaagcgagaccacgaaaggtgcctactgcctctcagtgtccgac
ttcgacaacgccaagggcctcaatgtgaagcactacaagatccgcaagctggacagcggc
ggcttctacatcacctctcgcacccagttcaacagtctgcagcagctcgtagcctactac
tccaagcatgccgacggcctgtgtcaccggctcaccactgtgtgccccacatccaagccg
cagactcagggcctggccaaggacgcctgggagatcccccgggagtcgctgcggctggag
gtcaagctgggccagggctgcttcggagaggtgtggatggggacctggaatggcaccacc
agagtggccatcaaaaccctgaagccaggcacgatgtctccagaggccttcctgcaggag
gcccaggtcatgaagaaactgaggcacgagaagctggtgcagctgtacgcagtggtgtct
gaggagcccatctacatcgtcacggagtacatgagcaaggggagtttgctggactttctc
aagggggagacaggcaagtacctgcggctgcctcaactggtggacatggcagctcagatc
gcctcaggcatggcatacgtcgagcggatgaattacgtccaccgggacctgcgtgcggcc
aacatcctggtgggagagaacctcgtgtgcaaagtggccgacttcggcctggctcggctc
atcgaggacaacgagtacacggcccggcaaggcgccaaattccccatcaagtggacagct
ccagaagccgccctctacggccggttcaccatcaagtcagacgtgtggtctttcgggatc
ctgctgacggagctcaccacaaaggggcgggtgccctaccccgggatggtaaaccgtgag
gtgctggaccaggtggagcggggctaccggatgccctgtccccctgagtgtcccgagtcc
ctgcacgacctcatgtgccagtgctggcggaaggagccggaggagcgacccaccttcgaa
tacctgcaggccttcctggaggactatttcacgtccacggagccccagtaccagcctgga
gagaacctatag

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