KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123816247
Entry
123816247         CDS       T07912                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01522  Endocrine resistance
phas04010  MAPK signaling pathway
phas04015  Rap1 signaling pathway
phas04068  FoxO signaling pathway
phas04071  Sphingolipid signaling pathway
phas04114  Oocyte meiosis
phas04148  Efferocytosis
phas04218  Cellular senescence
phas04261  Adrenergic signaling in cardiomyocytes
phas04370  VEGF signaling pathway
phas04380  Osteoclast differentiation
phas04517  IgSF CAM signaling
phas04550  Signaling pathways regulating pluripotency of stem cells
phas04611  Platelet activation
phas04613  Neutrophil extracellular trap formation
phas04620  Toll-like receptor signaling pathway
phas04621  NOD-like receptor signaling pathway
phas04622  RIG-I-like receptor signaling pathway
phas04625  C-type lectin receptor signaling pathway
phas04657  IL-17 signaling pathway
phas04658  Th1 and Th2 cell differentiation
phas04659  Th17 cell differentiation
phas04660  T cell receptor signaling pathway
phas04664  Fc epsilon RI signaling pathway
phas04668  TNF signaling pathway
phas04670  Leukocyte transendothelial migration
phas04714  Thermogenesis
phas04722  Neurotrophin signaling pathway
phas04723  Retrograde endocannabinoid signaling
phas04728  Dopaminergic synapse
phas04750  Inflammatory mediator regulation of TRP channels
phas04912  GnRH signaling pathway
phas04914  Progesterone-mediated oocyte maturation
phas04917  Prolactin signaling pathway
phas04926  Relaxin signaling pathway
phas04932  Non-alcoholic fatty liver disease
phas04933  AGE-RAGE signaling pathway in diabetic complications
phas04935  Growth hormone synthesis, secretion and action
phas04936  Alcoholic liver disease
phas05014  Amyotrophic lateral sclerosis
phas05020  Prion disease
phas05022  Pathways of neurodegeneration - multiple diseases
phas05132  Salmonella infection
phas05133  Pertussis
phas05135  Yersinia infection
phas05140  Leishmaniasis
phas05142  Chagas disease
phas05145  Toxoplasmosis
phas05152  Tuberculosis
phas05161  Hepatitis B
phas05163  Human cytomegalovirus infection
phas05167  Kaposi sarcoma-associated herpesvirus infection
phas05169  Epstein-Barr virus infection
phas05170  Human immunodeficiency virus 1 infection
phas05171  Coronavirus disease - COVID-19
phas05205  Proteoglycans in cancer
phas05208  Chemical carcinogenesis - reactive oxygen species
phas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
phas05415  Diabetic cardiomyopathy
phas05417  Lipid and atherosclerosis
phas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123816247 (MAPK11)
   04015 Rap1 signaling pathway
    123816247 (MAPK11)
   04370 VEGF signaling pathway
    123816247 (MAPK11)
   04668 TNF signaling pathway
    123816247 (MAPK11)
   04068 FoxO signaling pathway
    123816247 (MAPK11)
   04071 Sphingolipid signaling pathway
    123816247 (MAPK11)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123816247 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    123816247 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    123816247 (MAPK11)
   04218 Cellular senescence
    123816247 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    123816247 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123816247 (MAPK11)
   04613 Neutrophil extracellular trap formation
    123816247 (MAPK11)
   04620 Toll-like receptor signaling pathway
    123816247 (MAPK11)
   04621 NOD-like receptor signaling pathway
    123816247 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    123816247 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    123816247 (MAPK11)
   04660 T cell receptor signaling pathway
    123816247 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    123816247 (MAPK11)
   04659 Th17 cell differentiation
    123816247 (MAPK11)
   04657 IL-17 signaling pathway
    123816247 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    123816247 (MAPK11)
   04670 Leukocyte transendothelial migration
    123816247 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123816247 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    123816247 (MAPK11)
   04917 Prolactin signaling pathway
    123816247 (MAPK11)
   04926 Relaxin signaling pathway
    123816247 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    123816247 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    123816247 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    123816247 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    123816247 (MAPK11)
   04722 Neurotrophin signaling pathway
    123816247 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123816247 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123816247 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    123816247 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123816247 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    123816247 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123816247 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123816247 (MAPK11)
   05161 Hepatitis B
    123816247 (MAPK11)
   05171 Coronavirus disease - COVID-19
    123816247 (MAPK11)
   05163 Human cytomegalovirus infection
    123816247 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123816247 (MAPK11)
   05169 Epstein-Barr virus infection
    123816247 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123816247 (MAPK11)
   05135 Yersinia infection
    123816247 (MAPK11)
   05133 Pertussis
    123816247 (MAPK11)
   05152 Tuberculosis
    123816247 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123816247 (MAPK11)
   05140 Leishmaniasis
    123816247 (MAPK11)
   05142 Chagas disease
    123816247 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123816247 (MAPK11)
   05020 Prion disease
    123816247 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    123816247 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123816247 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    123816247 (MAPK11)
   05415 Diabetic cardiomyopathy
    123816247 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123816247 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    123816247 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123816247 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123816247 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:phas01001]
    123816247 (MAPK11)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     123816247 (MAPK11)
Protein kinases [BR:phas01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   123816247 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo Cas_CT1975
Other DBs
NCBI-GeneID: 123816247
NCBI-ProteinID: XP_045691073
LinkDB
Position
Unknown
AA seq 403 aa
MSGPRAGFYRQELNKTVWEVPQRLRGLRPVGSGAYGSVCSAYDTRLRQKVAVKKLSRPFQ
SLVHARRTYRELRLLKHLKHENVIGLLDVFTPATSVEDFSEVYLVTTLMGADLNNVVKCQ
VLSDEHVQFLVYQLLRGLKYIHSAGIIHRVGAGARAGLRGAACVPPVLPPLPPDPDPDPD
PDPTLQDLKPSNVAVNEDCELRILDFGLARQAEEEMTGYVATRWYRAPEIMLNWMHYNQT
AVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYLQSL
PPMPQKDLRSIFRGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEP
YDESVEEKERSVEEWKELTYQEVLSFKPPEPPQPPGGRDVVEQ
NT seq 1212 nt   +upstreamnt  +downstreamnt
atgtccggcccgcgcgccggcttctatcggcaggagctgaacaagacagtgtgggaggtg
ccgcagcgactgcgggggctgcgcccggtgggctcgggcgcctacggctccgtctgctcg
gcgtacgacacgcggctccgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcgctggtgcacgccaggcggacctaccgggagctgcggctgctcaagcacctgaagcac
gagaacgtcatcgggctgctggacgtcttcaccccggccacctccgtagaggacttcagc
gaagtgtacctggtgaccacgctgatgggcgccgacctgaacaacgtggtgaagtgccag
gtgctgagcgacgagcacgtccagttcctcgtgtaccagctgctgcgcgggctgaagtac
atccactcggccgggatcatccaccgggtaggtgcgggggcgagggccgggctccgcggg
gccgcctgcgttcctcccgtgctcccacccttgccacctgaccccgaccccgaccctgac
cccgacccgaccctgcaggacctgaagcccagcaacgtggcggtgaatgaggactgcgag
ctcaggatcctggacttcgggctggcccgccaggcggaggaggagatgaccggctacgtg
gccacccgctggtaccgcgcccctgagatcatgctcaactggatgcactacaaccagaca
gcagtggacatctggtctgtggggtgcatcatggcggagctcctccaggggaaggccctc
ttcccgggcagcgactacatcgaccagctgaagcgcatcatggaggtggtgggcacaccc
agccccgaggttctggccaagatatcgtcggaacatgcccggacgtacctccagtcgctg
ccccccatgccccagaaggacctccggagcatcttccgcggagccaaccccctggccgtg
gacctcttgggaaggatgctggtgctggacagcgaccagagggtcagtgcggccgaggcg
ctggcccacgcctacttcagccagtaccacgacccggacgacgagcccgaggccgagccg
tacgacgagagcgtggaggagaaggagcgctctgtggaggagtggaaggaactcacctac
caggaagtcctcagcttcaagcccccggagccaccgcagccgccgggcggccgggacgtc
gtcgagcagtga

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