Phyllostomus hastatus (greater spear-nosed bat): 123816701
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Entry
123816701 CDS
T07912
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00061
Fatty acid biosynthesis
phas00620
Pyruvate metabolism
phas00640
Propanoate metabolism
phas01100
Metabolic pathways
phas01212
Fatty acid metabolism
phas04152
AMPK signaling pathway
phas04910
Insulin signaling pathway
phas04922
Glucagon signaling pathway
phas04936
Alcoholic liver disease
Module
phas_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
123816701 (ACACA)
00640 Propanoate metabolism
123816701 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
123816701 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
123816701 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
123816701 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
123816701 (ACACA)
04922 Glucagon signaling pathway
123816701 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123816701 (ACACA)
Enzymes [BR:
phas01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
123816701 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
123816701 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
123816701 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
MetallophosN
Motif
Other DBs
NCBI-GeneID:
123816701
NCBI-ProteinID:
XP_045691788
LinkDB
All DBs
Position
Unknown
AA seq
2381 aa
AA seq
DB search
MDEVTQAKCISSFWKWISAQTVRIIRALRAHFEEIMDEPSHLAKPLELNQHSRFIIGSVS
EDNSEDEISNLVKLDLLEEKEGSLSPASVSSDTLSDVGISGLQDGLALHVRSSMSGLHLV
KQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMF
RNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAV
WAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGL
RVDWQESDFSKRILNVPQELYEKGYVKDVDDGLKAAEEVGYPVMIKASEGGGGKGIRKVN
NADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQ
KIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVE
HPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDAPIDFENSAHVPCPRGHV
IAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGE
NREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQLNRIDTGWLDRLIAEKVQAER
PDTLLGVVCGALHVADVSLRNSISNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVLKV
TRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVF
EKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAIESGCVHYVKRP
GAALDPGCVIAKMQLDNPSKVQQAELHTGSLPQIQSTALRGEKLHRVFHYVLDNLVNVMN
GYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQY
ASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKA
VVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNAVLNYIFSHAQVTKKNLLVTMLI
DQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFL
SAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNS
VQHRQLKDSTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNS
FTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSPPQSPTFPEAGHTSLYDEDKVPRDEP
IHILNVAIKTDGDIEDDRLAVMFREFTQQNKATLVEHGIRRLTFLVAQEDFRKQISYEVD
QRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYL
GAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTN
VRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKA
IPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQS
KRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDDQGQL
VHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASEL
ARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVDPEDPYKGFKYLYLTPQDYKRVSALN
SVYCEHVEDEGESRYKITDIIGKEEGLGAENLRGSGMIAGETSLAYDEIITISLVTCRAI
GIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHSTV
CDDFEGVFTVLHWLSYMPKSVNISVPILNSKDPIDRIIEFVPTKTPYDPRWMLAGRPHPT
QKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLD
SEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGA
YIIDGLRECSQPVMIYIPPQAELRGGSWVVIDPTINPRHMEMYADRESRASVLEPEGTVE
IKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKEREEFLTPIYHQVAVQ
FADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQ
AMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTEEDGVRSVVEENIKYISRDYVLKQIR
SLVQANPEVAMDSIVHMTQHISPTQRAEVVRILSTMDPPST
NT seq
7146 nt
NT seq
+upstream
nt +downstream
nt
atggatgaagtcactcaggcaaaatgtataagttctttttggaagtggatatctgctcag
acagtaagaatcataagagctctgagagctcattttgaagaaataatggatgaaccatcc
cacttggccaaacctttggagctaaaccagcactcccgattcataattggttctgtgtct
gaagataactcagaggatgagatcagcaacctggtgaagctggacctcctggaggagaag
gaaggttctttgtcaccagcttctgtcagctcagacacactctctgatgtgggaatctct
ggcctacaggatggcttggccttacatgtgaggtccagcatgtctggcttgcacctagta
aagcaaggtcgagaccgaaagaaaatagactcacagagagatttcactgtagcttctcca
gcagaattcgttactcgttttggggggaataaagtgattgagaaggttcttattgccaac
aatggcattgcagcagtgaaatgcatgcggtctatccgtcggtggtcttatgagatgttt
cgaaatgaacgtgcaatccgatttgttgtcatggtcacacctgaggatcttaaagccaat
gcagagtacattaagatggcagatcactatgtgccagtgccaggaggaccaaacaacaac
aactatgcaaatgtggaattaattcttgatattgctaaaaggatcccagtacaagcagtg
tgggctggctggggtcatgcttctgagaatcccaagctcccagaacttcttttgaaaaat
ggcatcgccttcatgggtccaccaagccaggccatgtgggctctgggggataagattgca
tcttccatagtggctcaaactgcaggcatcccaactctcccctggagtggcagtggtctt
cgtgtggactggcaagaaagtgatttttcaaaacgtattttaaatgttccccaggaactc
tatgaaaaaggctatgtgaaggatgtggatgacgggctaaaggcagcagaggaagttggg
tatccagtaatgatcaaggcctcagaaggaggaggaggaaagggaatcagaaaagtcaat
aatgcggatgacttccctaacctcttcagacaggttcaagctgaagtccctggctctcct
atatttgtgatgagactagcaaagcaatctcgtcatctggaggtgcagatcttggcagat
cagtatggcaatgctatctctttgtttggtcgcgattgctccgtacagcgcaggcatcag
aagattattgaagaggcacctgctgctatcgctactccagcagtatttgaacatatggag
cagtgtgcggtgaaacttgccaaaatggttggctatgtgagtgcggggactgtagaatac
ctttacagccaggatggcagcttctactttctggaactgaaccctcggctacaggtggag
cacccttgtacagagatggtggctgatgtcaacctccctgcagcacaactccagattgcc
atggggatccctctatacagaatcaaggatattcgtatgatgtatggggtatctccctgg
ggtgatgctcccattgattttgaaaattctgctcatgttccttgtccaaggggccatgtt
attgctgctcggatcactagtgaaaatccagatgagggttttaagcccagctcaggaaca
gttcaggaactgaacttccgcagcaataagaacgtctggggttatttcagtgttgctgct
gcagggggacttcatgagtttgctgattctcagtttggtcactgtttctcctggggagaa
aacagagaggaagcaatttcaaacatggtggtggctttgaaggagctgtctattcgaggt
gactttcgaactactgttgaatacctgatcaaattattggagactgaaagctttcagttg
aatagaattgacactggctggctggacagactgatagcagaaaaagtacaggcagagcga
cctgacaccctgttgggagttgtctgtggggctctccatgtggctgatgtgagcctgcgg
aatagcatctctaacttccttcactccttggaaaggggtcaagtccttcctgctcataca
cttctgaacactgtagatgttgaacttatctatgagggagtcaaatatgtccttaaggtg
actcggcagtcccctaactcctatgtggtgatcatgaacggctcctgtgtggaggtggat
gtgcatcggctgagtgatggaggactgctcttgtcctatgatggcagcagttataccacg
tacatgaaggaagaagtggatagatatcgcatcacgattggcaataaaacctgtgtgttt
gagaaggagaatgacccttcagtgatgcggtcaccttctgctgggaagttaatccagtac
attgtggaggacggaggccatgtgtttgctggccagtgctatgctgagattgaggtgatg
aagatggtaatgactttaacagctatagagtctggctgtgttcattacgtcaagcggcct
ggagcagctcttgatccgggctgtgtaatagccaaaatgcagttggataaccccagcaag
gtccagcaggctgagcttcacaccggtagtctgccacagatccagagcacagcacttcga
ggcgagaagctccatcgagtgttccactatgtcttggataatctggtcaacgtgatgaat
ggatactgccttccagatcctttctttagcagcagggtaaaagactgggtagagcggttg
atgaagaccctcagagatccctccttacctctcctagaattgcaagatatcatgaccagt
gtctctggccgcataccccccaacgtggagaagtctattaagaaggaaatggctcagtat
gctagcaacatcacatcagtcctctgtcagtttcccagccagcagattgccaacatccta
gatagccatgcagctacactgaaccggaaatctgaacgggaagtcttcttcatgaacact
cagagtatcgtccagctggtacagaggtaccgaagtggcatccgaggccacatgaaggct
gtggtgatggatctgctgcggcagtacctgcgagtggagacgcagttccagaatggtcac
tatgacaaatgtgtgttcgcccttcgggaggagaataagagtgacatgaacgctgtactg
aactatatcttctctcacgctcaagtcaccaagaagaatcttctggtcacaatgcttatt
gaccagttgtgtggccgggaccctactctcactgatgagctactgaatatcctcacagag
ctaactcaactcagtaagaccaccaatgccaaagtggcacttcgagcacgccaggttctt
attgcctctcatttgccatcatatgagcttcgccataaccaagtagagtctatcttccta
tcagctattgacatgtacggacatcagttttgtattgagaacctgcagaaactcatcttg
tctgaaacgtctatctttgatgtcttaccaaacttcttctatcacagcaaccaggtagtg
aggatggcagctctggaggtgtatgttcgaagggcttatattgcctatgaacttaacagc
gtacagcaccgccagcttaaggacagcacctgcgtggtggaattccagttcatgctgccc
acgtcccatccaaacagagggaacatccccacgctaaacagaatgtccttctcctccaac
ctcaaccactatggcatgactcatgtagctagtgtcagcgatgtgctgctggacaactca
ttcactccaccgtgtcagcggatgggcggaatggtctcttttcggacttttgaagatttt
gtcaggatctttgatgaagtgatgggctgcttctgtgattccccaccccaaagccccaca
ttccctgaggcgggtcacacatctctatacgatgaagacaaggtccccagggatgaacca
attcacattctcaatgtggctatcaagactgacggtgatattgaggatgacaggctggca
gtgatgttcagagagtttacccagcaaaataaagctactctggttgagcatggaatccgg
cgccttactttcctggttgcacaagaggatttcaggaaacagatcagctatgaggtggat
cagagatttcatagagaattccctaaatttttcacattccgagcaagggataagtttgag
gaggatcgtatctatcgtcacttggagcccgcccttgccttccagttagagctgaaccgg
atgagaaattttgaccttactgccattccatgtgctaatcacaagatgcacctgtatctt
ggggcagccaaagtggaagtgggcacagaagtgacagactataggttctttgtccgtgca
atcatcagacattctgatctggtcaccaaggaagcttcttttgaatatctgcaaaacgaa
ggggaacggctgctcctggaagccatggatgagttggaagttgcttttaataatacaaat
gtccgtaccgactgcaaccacatcttcctcaactttgtgcccacagtcatcatggaccca
tcaaagattgaggaatctgtgcggagcatggtaatgcgctatggaagtcggctgtggaaa
ttacgcgtcctccaggcagaactgaaaatcaacattcgcctgacaccaactggaaaagca
attcccattcgcctcttcctgacaaacgagtctggctattacttggacatcagcctatac
aaagaagtgactgactccaggacagcacagatcatgtttcaagcgtatggagacaaacag
ggaccattacatggaatgttaatcaacactccctatgtgaccaaagacctgcttcaatca
aagaggttccaggcacagtccttagggacaacatacatatatgatatcccagagatgttt
cgacagtccttgatcaaactctgggaatctatgtccactcaagcattccttccttcaccc
cctctgccttctgacatgctgacgtacaccgaactcgtgttggacgatcaaggccagctg
gtccacatgaacaggcttccaggaggaaatgagattggcatggtagcttggaagatgacc
cttaaaagtcctgaatatccagaaggtcgagatatcattgttattggcaatgacatcaca
taccgaattgggtcctttgggccccaggaggatttgctgtttctcagagcttctgagctt
gccagggcagaggggatcccacgcatctatgtagcagccaacagtggagcaagaattgga
ctggcagaggaaattcgtcatatgtttcatgtggcctgggtagatcctgaggatccttac
aagggattcaaatatttatacctgacccctcaagattataagagagtcagtgctctcaac
tctgtctattgtgaacacgtggaggatgaaggagaatccaggtacaagataaccgatatt
attgggaaggaagagggacttggagcagagaaccttcgaggttctggaatgattgctggg
gaaacctcgttggcctatgatgagatcatcaccattagcctggttacgtgccgagccatt
ggaattggtgcttaccttgtccggctgggacagagaaccatccaggttgaaaattctcac
ttaattctgacaggagccggggccctcaacaaagttctcgggcgggaagtctatacctcc
aataaccagctcggcggcatccagatcatgcacaacaatggggtgacccacagcactgtt
tgtgatgacttcgagggggttttcactgtcctgcactggctgtcttacatgcctaagagt
gtaaacatttcagttcccatcctgaattccaaggatcctatagatagaatcatcgagttt
gttcccacaaagaccccgtatgatcctcgatggatgctggcaggccgtcctcacccaacc
cagaaaggtcaatggttaagtggattttttgactatgggtctttctcagaaatcatgcaa
ccttgggcgcagactgtggtggttggcagagccagactaggaggaatacccgtgggagta
gttgctgtagaaacccggacagtggaactgagtatcccagctgatcctgcaaacctggat
tctgaagccaagataatccagcaagctggccaggtttggttcccagactctgcgtttaag
acctatcaggccatcaaggacttcaaccgtgaagggctgcccctgatggtctttgctaac
tggagaggcttctctggtgggatgaaagatatgtacgaccaagtgctgaaattcggtgct
tacatcattgatggcttacgggagtgctctcagcctgtgatgatttacatccctcctcag
gccgagcttcggggaggctcctgggtcgtgattgaccccaccatcaacccccggcacatg
gagatgtacgctgaccgagaaagcagggcatcagttctggagccagaagggacagtagaa
atcaaattccgaagaaaggatctggtgaaaaccatgcgtcgggtggacccagtctacatc
cacttggctgagcgattgggtaccccggagctcagtactgctgagcggaaggagctggag
aacaagctgaaggagcgggaggaattcctaactcccatttaccatcaggtagccgtgcag
tttgctgacttgcacgacaccccaggccggatgcaggagaagggtgtcattaacgacatc
ctggactggaagacatcccgcaccttcttctactggcggctgaggcgcctcctgctggag
gacctggtcaagaagaagatccacaatgccaaccccgagctgaccgatggccagatccag
gccatgctaaggcgctggtttgtggaagtggaaggcacggtgaaggcctacgtttgggac
aacaacaaggacctggtggagtggctggagaagcagctgacagaggaggacggggttcgc
tcagtcgtagaggaaaacatcaagtatatcagcagagactacgtcctcaagcagatccgc
agcttggtccaggccaacccagaggtcgccatggattccatcgtccacatgacccagcac
atctcccccacgcagcgagcagaagtcgtccggatcctctccacgatggaccccccctcc
acgtag
DBGET
integrated database retrieval system
