Phyllostomus hastatus (greater spear-nosed bat): 123816974
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Entry
123816974 CDS
T07912
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521
EGFR tyrosine kinase inhibitor resistance
phas01522
Endocrine resistance
phas01524
Platinum drug resistance
phas04010
MAPK signaling pathway
phas04012
ErbB signaling pathway
phas04020
Calcium signaling pathway
phas04066
HIF-1 signaling pathway
phas04151
PI3K-Akt signaling pathway
phas04510
Focal adhesion
phas04520
Adherens junction
phas04530
Tight junction
phas05200
Pathways in cancer
phas05205
Proteoglycans in cancer
phas05206
MicroRNAs in cancer
phas05212
Pancreatic cancer
phas05213
Endometrial cancer
phas05215
Prostate cancer
phas05219
Bladder cancer
phas05223
Non-small cell lung cancer
phas05224
Breast cancer
phas05226
Gastric cancer
phas05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123816974 (ERBB2)
04012 ErbB signaling pathway
123816974 (ERBB2)
04066 HIF-1 signaling pathway
123816974 (ERBB2)
04020 Calcium signaling pathway
123816974 (ERBB2)
04151 PI3K-Akt signaling pathway
123816974 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
123816974 (ERBB2)
04520 Adherens junction
123816974 (ERBB2)
04530 Tight junction
123816974 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123816974 (ERBB2)
05206 MicroRNAs in cancer
123816974 (ERBB2)
05205 Proteoglycans in cancer
123816974 (ERBB2)
05230 Central carbon metabolism in cancer
123816974 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
123816974 (ERBB2)
05226 Gastric cancer
123816974 (ERBB2)
05219 Bladder cancer
123816974 (ERBB2)
05215 Prostate cancer
123816974 (ERBB2)
05213 Endometrial cancer
123816974 (ERBB2)
05224 Breast cancer
123816974 (ERBB2)
05223 Non-small cell lung cancer
123816974 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123816974 (ERBB2)
01524 Platinum drug resistance
123816974 (ERBB2)
01522 Endocrine resistance
123816974 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123816974 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
phas04147
]
123816974 (ERBB2)
04090 CD molecules [BR:
phas04090
]
123816974 (ERBB2)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
123816974 (ERBB2)
Protein kinases [BR:
phas01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
123816974 (ERBB2)
Exosome [BR:
phas04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
123816974 (ERBB2)
CD molecules [BR:
phas04090
]
Proteins
123816974 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
123816974
NCBI-ProteinID:
XP_045692209
LinkDB
All DBs
Position
Unknown
AA seq
1253 aa
AA seq
DB search
MELAAWYRWGLLLALLPPGTADTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLHFLQDIQEVQGYVLIAHNQVRQVPLQRLRIIRGTQLFEDSYALAVLDNG
DLPDSATPAAGAAPGGLRELQLRSLTEILKGGVRIQRNPQLCHQDTILWTDIFHKNNQLA
LTVMDTNHSRACPPCSPACEHCWGESSRDCQSLTRTVCAGGCARCKGRRATDCCHEQCAA
GCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCPYN
YLSTDVGSCTLVCPVNNQEVTAEDGTQRCEKCSKPCARVCYGLGVEHLREARAVTSANIQ
EFAGCKKIFGSLAFLPESFEGDSTSSTAPLQPEQLRVFETLEEITGYLYISAWPDTLRDL
SVFQNLRVIRGRVLHDGAYSLTLQGLGIEWLGLRSLRELGSGLALVHHNAHLCFVHTVPW
DQLFRNPHQALLHSANRPEEECVGDGLACYHLCAHGRCWGPGPTQCVNCSQFLRGQECVE
KCRVLQGLPREYVKGRYCLPCHPECQPQNGSATCSGSGADQCVACTHYKDPPFCVARCPS
GVKPDLSFMPIWKFPDEEGTCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVGIL
LFMLMGIVTVILIRRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRK
VKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYV
SRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVRLV
HRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQ
SDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMID
SECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEE
YLVPQQGFFCPDPAPGAGSTAHRRHRSASTRSGGGELTLGLEPSEEEPPKSPLAPSEGAG
SDVFDGDLGMGAAKGMQSLPRLDSSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYVNQ
TEVRPKPPSPLEGPLPPPRPAGATLERPKTLSPGKNGIVKDIFTFGGAVENPEYLAPHSR
AAPQPHPPPAFSPAFDNLYYWDQDPPERGSPPSTFEGTPTAENPEYLGLNVPV
NT seq
3762 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtaccgctgggggctcctcctcgccctcctgccccccggaacc
gcagacacccaagtgtgcaccggcacagacatgaagctgcgcctcccggccagtcccgag
acccacttggacatgctccgccacctctaccagggctgtcaggtggtgcagggtaacctg
gagctcacctacttgcctgccaatgccagcctccacttcctgcaggatatccaggaggtg
cagggctacgtgctcatcgctcacaaccaggtgagacaggtcccgctgcagaggctgcgg
atcatacgaggcacccagctctttgaggacagctacgccctggccgtgctggacaacgga
gaccttccggacagcgccaccccagctgcaggggccgccccagggggcctgcgggagctg
cagctgcgaagcctcacagagatcctgaaaggaggggtccggatccagcggaacccccag
ctctgccaccaggacacgattctgtggacggacatcttccacaagaacaaccagctggcc
ctcacggtgatggacaccaaccactcccgggcctgcccgccctgctcgccagcctgtgaa
cactgctggggagagagctccagggactgtcagagcttgacccggactgtgtgcgccggt
ggctgtgcccgctgcaagggccggcgggccaccgactgctgccacgagcagtgcgctgcc
ggctgcacgggccccaaacactccgactgcctggcctgcctccacttcaaccacagtggc
atctgtgagctgcactgcccagccctggtcacctacaacacggacacctttgagtccatg
cccaaccccgagggccgttacaccttcggtgccagctgtgtgaccacctgtccctacaac
tatctgtcgacggacgtgggatcctgcaccctggtctgtcccgtgaacaaccaggaggtg
acagctgaggacgggacacagcggtgtgagaaatgcagcaagccctgtgctcgagtgtgc
tacggtctgggcgtggaacacctgcgagaggcgcgggcggtcaccagtgccaacatccag
gagttcgccggctgcaagaagatctttgggagcctggcgtttctgccagagagctttgag
ggggactccacctccagcaccgccccgctccagccggagcagctcagagtgtttgagacc
ctggaggagatcacaggttacctgtacatctcagcgtggccagacaccctgcgtgacctc
agtgtcttccagaacctgcgagtcatccggggacgagttctgcatgatggtgcctactcg
ctgaccctgcaagggctgggcatcgagtggctggggctgcgctcgctgcgggagctgggc
agcgggctggccctcgtccaccacaacgcccacctctgctttgtgcacacggtgccctgg
gaccagctctttcggaacccgcaccaggccctgctgcacagcgctaaccggccagaggag
gagtgtgtgggtgacggtctagcctgctaccacctctgcgcccacgggcgctgctggggg
ccggggcccacacagtgtgtcaactgcagccagttcctgcggggccaggagtgcgtggag
aagtgccgagtcctgcaggggctcccgcgcgagtacgtgaagggcaggtactgtctgccg
tgccaccccgagtgtcagccccagaacggctcggcgacctgctcgggatcgggggctgac
cagtgtgtggcttgcacccactacaaagaccctcccttctgcgtggcccgctgccccagc
ggtgtgaagcctgacctctccttcatgcccatctggaagttcccagacgaggagggcacg
tgccagccatgccccatcaactgcacccactcctgtgtggatctggacgacaagggctgc
cccgccgagcagagagccagccctgtgacgtccatcattgccgctgtggtgggcatcctg
ctgttcatgctcatgggcatagtcaccgtcatcctgatcaggagaaggcggcagaagatc
cgcaagtacacgatgcggaggctgctgcaggaaacggagctggtggagccgctgacaccc
agcggagcgatgcccaaccaggctcagatgcggatcctcaaagagacggagctgaggaag
gtgaaggtgcttggatccggagctttcggcaccgtctacaagggcatctggatccctgac
ggggagaacgtgaagatcccagtggccatcaaagtgttgagggaaaacacatctcccaaa
gccaacaaggaaatcttggatgaagcatatgtgatggctggtgtgggctccccgtatgtg
tcacgcctcctgggcatctgcttgacctccacggtgcagctggtgacacagctcatgccc
tacggctgcctcctggaccacgtccgagaacaccgcgggcgcctgggctcccaggacctg
ctgaactggtgtgtgcagatcgccaagggcatgagctatttggaggaggtgcggctcgtg
cacagggacctggctgcccggaatgtgctggtcaagagtcctaaccacgtcaagatcaca
gacttcgggctggctcggctgctggacattgacgagacggagtaccacgcggatgggggc
aaggtgcccatcaagtggatggcattggagtccattctccgccgacggttcacccaccag
agtgacgtgtggagctatggtgtgactgtatgggagctgatgacttttggggccaaacct
tacgacgggatcccggcccgagagatccccgacctgctggagaagggggaacggctgccc
cagccccccatctgcaccatcgatgtctacatgatcatggtcaaatgctggatgattgat
tccgaatgtcggccgaggttccgggagctggtggccgaattctcccgcatggccagggac
ccccagcgctttgtggtcatccagaacgaggacttgggccctgccagccccctggacagc
accttctaccggtcgctgctggaggacgacgacatgggggacctggtggacgctgaggag
tacctggtgccgcagcaaggcttcttctgcccggaccccgccccgggggccgggagcacg
gcccaccgcaggcaccgcagcgcgtccaccaggagtggcggtggcgagctgacgctgggg
cttgagccctccgaggaggagccccccaagtccccgctggcaccctcagaaggggcaggc
tctgacgtgtttgacggcgacttgggaatgggagcagccaaggggatgcagagcctcccc
aggcttgactccagccctctacagcggtacagcgaggaccccacggtacccctgccccct
gagactgatggctacgttgcccccctgacctgcagcccccagccagagtacgtgaaccag
acggaggttcgcccgaagcccccctcgccccttgagggccctctgcctcctcctcgacct
gcaggcgccactctggaaaggcccaagactctctccccagggaagaatgggattgtcaaa
gacattttcacctttggcggtgctgtggagaaccctgagtacttggcgccccacagcagg
gctgccccgcagccccaccctcctccagccttcagcccggcctttgacaacctctattac
tgggaccaggacccaccagagcggggctctccgcccagcacctttgaagggacccccaca
gcagagaaccccgagtacctgggcctgaacgtgcccgtgtga
DBGET
integrated database retrieval system
