Phyllostomus hastatus (greater spear-nosed bat): 123819931
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Entry
123819931 CDS
T07912
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521
EGFR tyrosine kinase inhibitor resistance
phas04062
Chemokine signaling pathway
phas04081
Hormone signaling
phas04148
Efferocytosis
phas04151
PI3K-Akt signaling pathway
phas04217
Necroptosis
phas04550
Signaling pathways regulating pluripotency of stem cells
phas04630
JAK-STAT signaling pathway
phas04658
Th1 and Th2 cell differentiation
phas04659
Th17 cell differentiation
phas04725
Cholinergic synapse
phas04917
Prolactin signaling pathway
phas04920
Adipocytokine signaling pathway
phas04933
AGE-RAGE signaling pathway in diabetic complications
phas04935
Growth hormone synthesis, secretion and action
phas05140
Leishmaniasis
phas05145
Toxoplasmosis
phas05152
Tuberculosis
phas05161
Hepatitis B
phas05164
Influenza A
phas05167
Kaposi sarcoma-associated herpesvirus infection
phas05168
Herpes simplex virus 1 infection
phas05200
Pathways in cancer
phas05207
Chemical carcinogenesis - receptor activation
phas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
phas05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
123819931 (JAK2)
04151 PI3K-Akt signaling pathway
123819931 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
123819931 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123819931 (JAK2)
09143 Cell growth and death
04217 Necroptosis
123819931 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
123819931 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
123819931 (JAK2)
04659 Th17 cell differentiation
123819931 (JAK2)
04062 Chemokine signaling pathway
123819931 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
123819931 (JAK2)
04917 Prolactin signaling pathway
123819931 (JAK2)
04935 Growth hormone synthesis, secretion and action
123819931 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
123819931 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123819931 (JAK2)
05207 Chemical carcinogenesis - receptor activation
123819931 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123819931 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
123819931 (JAK2)
05164 Influenza A
123819931 (JAK2)
05168 Herpes simplex virus 1 infection
123819931 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
123819931 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
123819931 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
123819931 (JAK2)
05140 Leishmaniasis
123819931 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123819931 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
123819931 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123819931 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123819931 (JAK2)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123819931 (JAK2)
Protein kinases [BR:
phas01001
]
Non-receptor tyrosine kinases
JAK family [OT]
123819931 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
123819931
NCBI-ProteinID:
XP_045696477
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MEMACLTMTEMEGTSTFPIHHNGDIPGIVDSVKQIDPVLQVYLYHSLGKAEGDNLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHIFHIDESTRHSVLYRIRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLDIYNSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQEVSNESRIVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKRAGNQT
GLYVLRCSPKEFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFNNLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKTSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCAKNILLIREEDRKIGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKSLNLATDKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTFQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRHLALRVDQIRDNMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atggaaatggcttgccttacaatgacagaaatggaaggaacatccacatttcctatacat
cataatggtgatattcctggaattgttgattctgtgaagcaaatagatccagtcctacag
gtgtatctttatcattcccttgggaaagctgagggagataacctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcctgcggaatcacaccagtg
tatcatagcatgtttgccttaatgagtgaaacagaaaggatctggtatccacccaaccac
atcttccatatagatgagtcaacaaggcacagtgttctctacagaataagattttacttt
ccttactggtattgtaacggcagcaatagaacctatcggcatggtatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgtcatgat
tttttgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgttagatatgatgagaatagccaaagaaaaggatcaaaccccactggacatc
tataactctatcagctacaagacattcttaccaaaatgtgtgcgagcaaagatccaagac
tatcatattttgacaagaaagcgaataaggtacagatttcgcagattcattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgcattctacacagaacaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaagcaggcaaaccaagaagtctcaaatgaaagcaga
attgtaactattcataaacaagatggtaaaaatctggaaattgaacttagctcattaagg
gaagctttgtcctttgtgtcattaattgatggatattatagattaactgcagatgcacat
cattacctctgtaaagaagtggcacctccaatggtgcttgaaaatatacaaagcaactgt
catggtccaatttcgatggattttgccataagtaaactgaagagagcaggtaatcagact
ggactctatgtacttcgatgcagtcctaaggagtttaataaatattttttgacttttgct
gttgagcgagaaaatgtcattgaatataagcactgtttgattacaaaaaatgagaatgga
gaatacaacctcagtgggactaagaagaacttcaataatcttaaagatcttttgaattgc
tatcagatggaaactgttcgctcagacaatataattttccagtttacaaaatgctgtccc
ccaaagccaaaagataaatctaacctcttagtctttagaaccaatggtgtttctgatgta
ccaacctcaccaacactacagaggcataataatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttgatatttaatgaaagccttgggcaaggcactttcacaaaaattttt
aaaggtgtaagaagagaaataggagactatggtcaactgcatgagacagaagttctttta
aaagttttggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcatctggttttaaattacggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtgaaatttggatcactagatacatatttaaaaaag
aataaaacttctataaatatattatggaaacttgaagtggctaaacagctggcatgggcc
atgcattttctagaagaaaaaacccttatccatgggaatgtgtgtgccaaaaatattcta
cttatcagagaagaagacaggaagataggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccgtgggtaccg
cctgaatgcattgaaaatcctaaaagtttaaacttggcaacagacaagtggagttttggt
accactttgtgggaaatctgcagtggaggagataagcctctgaatgctttggattctcag
agaaagctacagttttatgaagatagacaccagcttcctgcaccaaaatggacagagtta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttccttcagagcc
atcatacgagatctaaacagtttgtttactcctgattatgaactattaacagagaatgac
atgttaccaaatatgaggataggtgccctagggttttctggtgcttttgaagaccgagac
cctactcagtttgaagagagacacttgaaatttctgcagcagcttggcaagggtaatttt
gggagtgtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggct
gtgaagaagcttcagcacagtactgaagagcacctcagggactttgaaagggaaattgaa
atccttaaatccctgcaacatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatttaagattaattatggaatatttaccatatggaagtttacgtgactat
ctccagaagcataaagaacggatagatcataaaaaacttctgcagtacacatttcaaata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaagg
aacatattggtggagaatgaaaacagagttaaaattggagattttggattaaccaaagtc
ttgccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaa
ttcatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagag
ctcttgaagaataatggaaggttacctagaccagatggatgcccggatgagatttatgtg
atcatgacagaatgctggaacaataatgtaaatcaacgcccctcttttagacacctcgct
cttcgagttgatcaaataagggacaatatggctggatga
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integrated database retrieval system
