Phyllostomus hastatus (greater spear-nosed bat): 123820487
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Entry
123820487 CDS
T07912
Symbol
ADCY4
Name
(RefSeq) adenylate cyclase type 4 isoform X1
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00230
Purine metabolism
phas01100
Metabolic pathways
phas01522
Endocrine resistance
phas04015
Rap1 signaling pathway
phas04020
Calcium signaling pathway
phas04022
cGMP-PKG signaling pathway
phas04024
cAMP signaling pathway
phas04062
Chemokine signaling pathway
phas04072
Phospholipase D signaling pathway
phas04081
Hormone signaling
phas04082
Neuroactive ligand signaling
phas04114
Oocyte meiosis
phas04211
Longevity regulating pathway
phas04213
Longevity regulating pathway - multiple species
phas04261
Adrenergic signaling in cardiomyocytes
phas04270
Vascular smooth muscle contraction
phas04371
Apelin signaling pathway
phas04540
Gap junction
phas04611
Platelet activation
phas04713
Circadian entrainment
phas04714
Thermogenesis
phas04723
Retrograde endocannabinoid signaling
phas04724
Glutamatergic synapse
phas04725
Cholinergic synapse
phas04727
GABAergic synapse
phas04742
Taste transduction
phas04750
Inflammatory mediator regulation of TRP channels
phas04911
Insulin secretion
phas04912
GnRH signaling pathway
phas04913
Ovarian steroidogenesis
phas04914
Progesterone-mediated oocyte maturation
phas04915
Estrogen signaling pathway
phas04916
Melanogenesis
phas04918
Thyroid hormone synthesis
phas04921
Oxytocin signaling pathway
phas04923
Regulation of lipolysis in adipocytes
phas04925
Aldosterone synthesis and secretion
phas04926
Relaxin signaling pathway
phas04927
Cortisol synthesis and secretion
phas04928
Parathyroid hormone synthesis, secretion and action
phas04934
Cushing syndrome
phas04935
Growth hormone synthesis, secretion and action
phas04970
Salivary secretion
phas04971
Gastric acid secretion
phas04972
Pancreatic secretion
phas04976
Bile secretion
phas05032
Morphine addiction
phas05163
Human cytomegalovirus infection
phas05166
Human T-cell leukemia virus 1 infection
phas05200
Pathways in cancer
phas05207
Chemical carcinogenesis - receptor activation
phas05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123820487 (ADCY4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
123820487 (ADCY4)
04072 Phospholipase D signaling pathway
123820487 (ADCY4)
04024 cAMP signaling pathway
123820487 (ADCY4)
04022 cGMP-PKG signaling pathway
123820487 (ADCY4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
123820487 (ADCY4)
04081 Hormone signaling
123820487 (ADCY4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123820487 (ADCY4)
04062 Chemokine signaling pathway
123820487 (ADCY4)
09152 Endocrine system
04911 Insulin secretion
123820487 (ADCY4)
04923 Regulation of lipolysis in adipocytes
123820487 (ADCY4)
04913 Ovarian steroidogenesis
123820487 (ADCY4)
04915 Estrogen signaling pathway
123820487 (ADCY4)
04921 Oxytocin signaling pathway
123820487 (ADCY4)
04926 Relaxin signaling pathway
123820487 (ADCY4)
04935 Growth hormone synthesis, secretion and action
123820487 (ADCY4)
04918 Thyroid hormone synthesis
123820487 (ADCY4)
04928 Parathyroid hormone synthesis, secretion and action
123820487 (ADCY4)
04925 Aldosterone synthesis and secretion
123820487 (ADCY4)
04927 Cortisol synthesis and secretion
123820487 (ADCY4)
09154 Digestive system
04970 Salivary secretion
123820487 (ADCY4)
04971 Gastric acid secretion
123820487 (ADCY4)
04972 Pancreatic secretion
123820487 (ADCY4)
04976 Bile secretion
123820487 (ADCY4)
09156 Nervous system
04724 Glutamatergic synapse
123820487 (ADCY4)
04727 GABAergic synapse
123820487 (ADCY4)
04725 Cholinergic synapse
123820487 (ADCY4)
04723 Retrograde endocannabinoid signaling
123820487 (ADCY4)
09157 Sensory system
04742 Taste transduction
123820487 (ADCY4)
04750 Inflammatory mediator regulation of TRP channels
123820487 (ADCY4)
09149 Aging
04211 Longevity regulating pathway
123820487 (ADCY4)
04213 Longevity regulating pathway - multiple species
123820487 (ADCY4)
09159 Environmental adaptation
04713 Circadian entrainment
123820487 (ADCY4)
04714 Thermogenesis
123820487 (ADCY4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123820487 (ADCY4)
05207 Chemical carcinogenesis - receptor activation
123820487 (ADCY4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
123820487 (ADCY4)
05163 Human cytomegalovirus infection
123820487 (ADCY4)
09165 Substance dependence
05032 Morphine addiction
123820487 (ADCY4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
123820487 (ADCY4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123820487 (ADCY4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
123820487 (ADCY4)
Enzymes [BR:
phas01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
123820487 (ADCY4)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
DUF3180
CD52
Motif
Other DBs
NCBI-GeneID:
123820487
NCBI-ProteinID:
XP_045697195
LinkDB
All DBs
Position
Unknown
AA seq
1101 aa
AA seq
DB search
MARLFSPGPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALLALLVVASASGRELTSDPG
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGHGFLFTGGVVSAWDQV
SFFLFVIFTTYAMLPLGMRDATAAGLVSSLSHLLVLGLYLGPQLDSRPALLPQLAANTVL
FLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAG
AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR
YLESWGAAKPFAHLSHIESPVSTSTPLQVEFGGERAVIRGSRNSRIKCSRSKEKALASFS
PQWSLDRSRTPRGLDDELDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEY
RLSALPAFKYYAACTFLVFLSNFTIQMLVTNRPPALAITYSITFLLFLLLLFVCFSEHLT
RCVLKGPKMLHWLPALSGLVATRPGLRVALGTATILLIFAMAIASLFFTPATSNCPFRAP
NVSSVAFNLSWELPGSLPLISIPYSMHCCILGFLSCSLFLHMSFELKLLLLLLWLAASCS
LFLHSHAWLSDCLVARLYQGSLDSRPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRL
DFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLF
ASVPDFKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATG
LNATSGQDAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGV
IGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQALGYTCYRRGVIKVKGKGQ
LCTYFLNTDLTRAGPPSATLG
NT seq
3306 nt
NT seq
+upstream
nt +downstream
nt
atggccagactcttcagtcccgggccgccgcccagcgaagacctcttctacgagacctac
tacagcctgagccagcagtacccgctcctgctactgctgctggtgatcgtgctctgtgcg
ctcctggccctgcttgttgtcgcctcagccagcggcagggagttgacctcagacccgggc
ttcctgaccacggtgctgtgcgcgctgggtggcttctcactgctgctgggcctggcctcc
cgcgagcaacgactgcagcgctggacgcgtcccctgtcgggcctcgtgtgggcagcgctg
cttgctctaggccacggtttcctgtttactgggggcgtggtgagcgcctgggaccaggtg
tcctttttcctctttgtcatcttcactacgtatgccatgttgcccttgggcatgcgggac
gccactgctgcgggtcttgtctcgtcactctcacacctgctggtcctcgggctgtatctt
gggcctcagctggactcaagacccgcgctgctgccgcagctggcagcaaacacggtgttg
ttcctgtgcgggaatgtggccggagtgtaccacaaggcattgatggagcgggcactgcgc
gccaccttccgagaggcgcttagttccctgcactctcgccggcggctggacacagagaag
aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag
gcagagatcatggcacggctgcaggctggacaggggtcgaggccagagaacaccaacaac
ttccacagtctctatgtcaagaggcaccagggagtcagtgtgctgtatgctgatatcgtg
ggcttcacgcggctagccagtgagtgctccccaaaggagttggtgctgatgctcaatgag
ctctttggcaagttcgaccagatcgccaaggagcacgaatgcatgcggatcaagatcctg
ggagactgttactactgtgtctccgggctgcccctctccctgccagaccacgccatcaac
tgtgtgcgcatggggctggacatgtgccgggccatcaggaaactgcgagcagccaccggc
gtggacatcaacatgcgcgtgggtgtgcactcaggcagcgtgctctgtggagtcatcggg
ctgcagaagtggcagtatgatgtctggtcccatgacgtcacattagccaaccacatggag
gcgagcggcgtgccaggacgagtgcacatcacaggggctaccctggccctgctggcagga
gcttacgctgtggaggatgcagccatggaacaccgggacccgtacctgcgggagctaggg
gagcctacctacctggtcatcgatccccgggctgaggaggaggatgagaagggcactgca
ggagggttgctgtcctctctggagggccccaagatgcgtccatcactgttgatgacccgc
tatctggaatcctggggtgcagccaagccttttgctcacctaagccacattgagagccct
gtgtccacttctactcctctccaggtggaatttggtggagagagagcagtcattagaggc
agcagaaacagccgtatcaaatgctcaaggtcaaaggagaaggccctggcttccttcagc
ccccagtggagcctggaccggagccgtacaccccggggactagatgatgaactagacacc
ggggatgccaagttcttccaggtcatcgaacagctcaactctcagaaacagtggaagcag
tcaaaggacttcaacccgctgacactgtactttcgagagaaggaaatggagaaagagtat
cgactgtctgcactccccgccttcaaatactacgcggcctgcaccttcctggtttttctc
tccaacttcaccatccagatgctggtgacaaacaggcccccagcgctggccatcacctat
agcatcaccttcctcctcttcctcctcctcctcttcgtctgcttctcagagcacctgacg
aggtgtgtcttgaaaggccccaaaatgctgcactggctgccagcactgtctggcctggtg
gccacccggcctggactgcgagttgccctgggcactgccaccatcctcctcatctttgcc
atggccattgccagcctgttcttcacaccggcaacatcaaactgccctttccgggctccc
aatgtgtcctccgtggctttcaacctctcttgggagctccctgggtccctgcctctcatc
agcattccatactccatgcactgctgcatactggggttcctctcctgctccctctttctg
cacatgagctttgaactgaagctgctgctgctcctgctatggctggcggcctcctgctcc
ctcttcctgcactcccatgcctggctgtccgactgcctcgtcgcccgcctctatcagggc
tccttggactccaggcctggagtgctaaaggagcccaaactgatgggagctatctccttc
ttcatcttcttcttcacactccttgtcttggctcggcagaatgagtattactgccgcctg
gatttcctgtggaagaagaagctgaggcaggagagggaggagacggagacaatggagaat
ttgactcggctgctcttggagaatgtgcttcctgcacacgtggccccccagtttattggc
cagaaccggcgcaatgaggacctctaccaccagtcctacgaatgtgtctgtgtcctcttc
gcctcagtcccagacttcaaggagttttactctgaatccaacatcaaccatgaggggcta
gagtgtctgcggctgctcaatgagatcattgctgattttgatgagctgctctctaagccc
aagttcagtggggtggagaaaatcaaaaccattggcagcacctacatggcagctacaggc
ctaaatgccacctctggacaggatgcacagcaggatgctgagcgaagctgcagccacctt
ggcaccatggtggaatttgcagtggcccttgggtctaagctggacgttatcaacaagcac
tcattcaacaacttccgcttgcgtgtggggctgaaccatggacctgtagtggctggagtg
ataggggcccagaaaccacaatacgacatctggggcaacacggtgaatgtggccagccgc
atggagagcacaggagtcctgggcaagatccaagtaacagaggagacagcctgggccctg
caggctttaggctacacctgctaccgcagaggtgttatcaaggtcaaaggcaaagggcag
ctgtgcacctacttcctgaacacagatttgacacgagctggacctccctcagccacacta
ggctga
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