| Entry |
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| Symbol |
NOS1
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| Name |
(RefSeq) nitric oxide synthase, brain
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| KO |
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| Organism |
phas Phyllostomus hastatus (greater spear-nosed bat)
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| Pathway |
| phas05022 | Pathways of neurodegeneration - multiple diseases |
| phas05412 | Arrhythmogenic right ventricular cardiomyopathy |
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| Brite |
KEGG Orthology (KO) [BR:phas00001]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
123820989 (NOS1)
00330 Arginine and proline metabolism
123820989 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
123820989 (NOS1)
04020 Calcium signaling pathway
123820989 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
123820989 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
123820989 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
123820989 (NOS1)
09154 Digestive system
04970 Salivary secretion
123820989 (NOS1)
09156 Nervous system
04730 Long-term depression
123820989 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
123820989 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123820989 (NOS1)
05014 Amyotrophic lateral sclerosis
123820989 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
123820989 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123820989 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
123820989 (NOS1)
05414 Dilated cardiomyopathy
123820989 (NOS1)
05416 Viral myocarditis
123820989 (NOS1)
Enzymes [BR:phas01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
123820989 (NOS1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1468 aa
MENHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGQPLVDLSYENALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTQPLGPPTTAVDLSHQSSACKEQLPPVDGATGPGNGPQHTHDNGQEAGSLSHTNGLAP
RPPGPDPAKKNAGVTLQGRGEHNDLLKEIEPVLNLLTSGDRRINGGGPDKAETKDAEVQV
DRNLDDKSHKPLPLGVENDRVFSDLWGKGNVPVVLNNPYSEKEQSPASGKQSPTKNGSPS
KCPRFLKVKNWETDVVLTDTLHLKSTLETGCSEHICMGSVMHTSQQLRRPEDIRTKEQLF
PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRIDSKHDFRVW
NAQLIRYAGYKQPDGSILGDPANVEFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMNLDMKRTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVH
EERKYPEPLRFFPRKGPPLPRGDTGVRGLAGVRDSQLRSYKVRFNSVSSFSDSRKSSGDG
PDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLAYVAEAPELT
QGLSSVHKKRVSAARFLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHE
DLVNTLIERLEDAPPVNQLVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDIT
TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFQSIQMPAT
LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPIHHGVCSSWLNRIQSD
EVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVF
GCRQSQIDHIYKEETLQARSLGVFRELYTAYSREPDKPKKYVQDVLQEKLAEPVYRALRE
QGGHIYVCGDVTMAADVLKAIQRIMAQQGKLSVEDAGVFISRLRDDNRYHEDIFGVTLRT
YEVTNRLRSESIAFIEESKKDTDEVFSS |
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| NT seq |
4407 nt +upstreamnt +downstreamnt
atggagaaccacatgttcagcgtccagcaaatccagcccaacgtgatttctgtccgcctc
ttcaagcgcaaagtggggggcctgggctttctggtgaaggagcgagtgagcaagcccccc
gtgatcatctctgacctgattcgcgggggagccgcagagcagagcggcctcatccaggct
ggagacatcattctggcagtcaatggccagccgttggtggacctgagttatgagaatgcc
ttggaggtgctccggggcattgcttccgagacccacgtggtcctcatcctgcggggccct
gagggcttcaccacgcacctggagaccacctttactggggatgggacccccaagaccatc
cgggtgacacagcccctgggtccccccaccacagctgtcgatctgtcgcaccagtcatca
gcctgcaaagagcagctgcccccagtggatggggccaccggtcctggcaatgggccacag
catacccacgacaatgggcaggaggctggctcgctgtcccacaccaacggcctggcgccc
aggcctccaggcccggaccctgccaagaagaatgctggggtcacccttcagggccgtggg
gagcacaatgacttgctcaaagagatagagcctgtgctgaaccttctcaccagtggtgac
agacggatcaatggagggggaccggacaaagcagagacaaaagacgcagaagtccaggtg
gacagaaatctggatgacaagtctcacaaacctctgcccctcggcgtggagaatgaccga
gtcttcagtgacctgtgggggaagggcaacgtgcctgtggtcctcaacaacccgtattcg
gagaaagagcagtcccctgcttcgggaaaacagtcccccacaaagaatggcagcccctcc
aagtgcccccgcttcctcaaggtcaagaactgggagactgatgtggttctcacggacacc
ctccaccttaagagtacattggagacgggatgcagcgagcacatctgcatgggctccgtc
atgcacacctctcagcagttgcggaggccggaagacatccgcactaaggagcagctcttc
cctctcgccaaagagtttatcgatcagtactactcgtccattaaaagatttggctccaaa
gcccacatggagaggctggaagaggtgaacaaagagattgaaaccaccagcacctaccag
ctcaaagacacggagctcatctacggggccaagcatgcctggaggaatgcctcccgctgc
gtcggcaggatccagtggtccaaactgcaggtgtttgatgcccgagactgtaccacggct
catgggatgttcaactacatctgcaaccacatcaagtatgccaccaacaaagggaacctc
aggtccgccatcaccatatttccccagagaatcgacagcaagcacgatttccgagtctgg
aacgcccagctcatccgctatgccggctacaagcagcctgacggctccatcctaggggac
ccagccaacgtggagttcacggagatctgcatacagcagggctggaaacccccgcggggt
cgcttcgacgtcctgccactcctgctccaggccaacggcaacgaccccgagctcttccag
atccctccagagctggtgttggaagtgcccatcaggcaccccaagtttgagtggttcaag
gacctggggctgaagtggtacggcctccccgctgtgtccaacatgcttctggagattggt
ggcctggagttcagcgcctgccccttcagcggctggtacatgggcacggagattggcgtc
cgtgactactgtgacaactctcggtacaacatcctggaggaagtggccaagaagatgaac
ttggacatgaagaggacgtcctccctgtggaaggaccaggcgctggtggagatcaacatt
gcagtcctctacagtttccagagtgacaaagtgaccatcgtcgaccaccactcggccacc
gagtctttcatcaagcacatggagaatgaataccgctgccgggggggctgtcccgcagac
tgggtgtggattgtgccccccatgtctggcagcatcacccctgtcttccaccaggagatg
ctcaactaccggctcaccccctccttcgagtaccagcctgacccttggaacacccacgtc
tggaaaggcaccaacgggacccccacaaagcggcgagccattggcttcaagaagctggca
gaagccgtcaagttctcagccaagctgatggggcaggcaatggccaagagggtcaaggca
accatcctttatgccacagagacgggcaaatcacaggcctatgccaaaaccttgtgtgag
atcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatatgacattgtgcac
ctagaacatgaaactctggtcctggtggtcaccagcacctttggcaacggagacccccct
gaaaatggggagaagttcggctgcgctctgatggaaatgaggcaccccaactctgtgcac
gaggaaaggaagtacccggaacccttgcgtttctttccccgtaaagggcctcccctcccc
cgaggcgacacaggagtccgtggtctggctggagtccgtgacagccagctcaggagctac
aaggtcaggttcaatagtgtttcctccttttccgactcccgcaaatcatcaggcgacggg
ccagacctcagagacaactttgagagcaccggccccctggcaaacgtgaggttctcggtg
ttcggccttggctcgcgggcctacccccacttctgcgccttcggacatgccgtggacacc
ctcctggaggagctgggaggagagaggatcctgaagatgagggagggggacgagctctgt
gggcaggaggaggcgttcaggacctgggccaagaaggtcttcaaggcagcctgcgatgtg
ttctgcgtgggggacgacgtcaacatcgagaaggcgaacaactcgctcatcagcaatgac
cgcagctggaagaggaacaagttccgcctcgcctacgtggctgaggctccggagctcacg
caaggtctctccagtgtccacaagaagcgggtctcggccgctcgcttcctcagccgtcaa
aaccttcagagccccaagtccagccggtcaaccatcttcgtgcgtctccacaccaacggg
aatcaggagctgcagtaccagcctggggaccacctgggcgtcttccctggcaaccacgag
gacctcgtgaacaccctgatcgagcggctggaggacgcgccccccgtcaaccagctggtg
aaagtagaactgctggaggagcggaacacagctctgggagtcatcagtaactggacggat
gagcaccgcctcccgccctgcaccatcttccaggccttcaagtactacctggacatcacc
acgccgcccacgcccctgcagctgcagcagtttgcctccctggccaccagcgaaaaggag
aagcagcgcctgctggtcctcagcaagggcttacaggagtacgaggagtggaaatggggc
aagaaccccaccatcgtggaggtgctggaggagttccagtccatccagatgcccgccacc
ctgctcctgacccagctgtccctcctgcagcctcgctactactccatcagctcctcccca
gacatgtaccccgacgaggtgcacctcaccgtggccatcgtctcctaccacacccgagat
ggagaaggaccaatccaccatggcgtgtgctcctcctggttgaaccggatccagtctgat
gaagtggtcccctgcttcgtgagaggagcacccagcttccacctgccccgaaacccccaa
gtgccctgcatcctggttggcccgggcaccggcattgcccctttccgaagcttctggcag
cagcggcaatttgatatccagcacaaaggaatgagtccctgccccatggtcctggtcttc
gggtgccggcagtcccagatagaccacatctacaaggaggagaccctgcaggcccggagc
ttgggggtcttccgagagctgtacacggcctactcccgggagccggacaaaccaaagaag
tacgtgcaggacgtcctgcaggagaagctggcggagcctgtgtaccgagccctgcgggag
caagggggccacatttacgtctgcggggacgtcaccatggccgccgacgtcctcaaagcc
atccaacgcatcatggcccagcaggggaagctctcggtggaggacgccggcgtgttcatc
agccggctgcgggatgacaaccgctaccatgaggatattttcggggtcaccctgcgcacg
tacgaagtgaccaaccgccttagatctgaatccattgccttcattgaggagagcaaaaag
gacaccgacgaggtttttagctcctaa |
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