Phyllostomus hastatus (greater spear-nosed bat): 123821051
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Entry
123821051 CDS
T07912
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00760
Nicotinate and nicotinamide metabolism
phas01100
Metabolic pathways
phas04068
FoxO signaling pathway
phas04148
Efferocytosis
phas04152
AMPK signaling pathway
phas04211
Longevity regulating pathway
phas04213
Longevity regulating pathway - multiple species
phas04218
Cellular senescence
phas04310
Wnt signaling pathway
phas04922
Glucagon signaling pathway
phas04936
Alcoholic liver disease
phas05031
Amphetamine addiction
phas05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
123821051 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
123821051 (SIRT1)
04068 FoxO signaling pathway
123821051 (SIRT1)
04152 AMPK signaling pathway
123821051 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123821051 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
123821051 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123821051 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
123821051 (SIRT1)
04213 Longevity regulating pathway - multiple species
123821051 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123821051 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
123821051 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123821051 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
phas03036
]
123821051 (SIRT1)
03029 Mitochondrial biogenesis [BR:
phas03029
]
123821051 (SIRT1)
Enzymes [BR:
phas01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
123821051 (SIRT1)
Chromosome and associated proteins [BR:
phas03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
123821051 (SIRT1)
Mitochondrial biogenesis [BR:
phas03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
123821051 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Bt_P21
Motif
Other DBs
NCBI-GeneID:
123821051
NCBI-ProteinID:
XP_045698293
LinkDB
All DBs
Position
Unknown
AA seq
731 aa
AA seq
DB search
MADEAALALQPGGSPSAVAAEWEAPSPPTGEPLSKRPRRDVPGLGWSPGEPEEAAPEHEL
LSVAGDGRAAAGGEQEAPATAGGIGDNGPGLQGLSRDPPPADDFDDEDEDEEGEEEEEAA
AEIEYRDNLFRDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPYAFVQQHLMIGTDP
RTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIV
LTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYP
GQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFAAASCLICKYKV
DCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIV
IGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYA
KLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEGSSSPERTSPPNSSVIVTLLDQ
ATKSNVDDPDMSESKDCMEEQSQVVQTSTRSTESVTEQLESPDLKSIGSSTGEKDERTSV
AETVRKCWPSKLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSD
SGTCQSPSLEEPIEDESEIEEFYNGLEDDADINERAGGTEFGADGGDQEAVNDAVSMKQE
ATDINYQSNKS
NT seq
2196 nt
NT seq
+upstream
nt +downstream
nt
atggcggatgaggcggcgctcgcccttcagcccggcggctccccttcggcggtggcggcc
gagtgggaggccccgtcgccgcccaccggggagcctctcagcaagaggccgcggagagac
gtcccgggcctcggatggagcccgggcgagcccgaagaggcagcccctgagcatgagctg
ctttcggtggccggggacggccgggcggcggctggcggggagcaggaggccccggcgacg
gcaggcggaataggagacaatgggccgggcctacagggcctatcccgggacccgccaccg
gccgacgacttcgacgacgaggacgaagacgaagagggagaggaggaggaagaggcagcg
gcggagattgagtaccgagacaacctgtttcgtgatgaaataatcacaaatggttttcat
tcgtgtgaaagtgatgaggatgatagagcctcacatgcaagctctagtgactggactcca
aggccaaggataggtccatatgcttttgttcagcaacatctcatgatcggcacagatcct
cgaacaattcttaaagatttactaccagaaacaattcctccacctgaattggatgatatg
acactgtggcagattgttattaatatcctttcagaaccaccaaaaaggaaaaaaagaaaa
gatattaatacaattgaagatgctgtgaaattactgcaggaatgcaaaaaaataatagtt
ctaactggagctggggtttctgtttcttgtggaatacctgacttcaggtcaagagatggt
atttatgctcgccttgcagtagacttcccagatcttccagatcctcaagcaatgtttgat
attgaatatttcagaaaagatccaagaccattcttcaagtttgcaaaggaaatatatcct
ggacagttccaaccatctctctgtcacaaattcatagccttgtcagataaagaaggaaaa
ctacttcgcaactacactcagaatatagatacactggaacaggttgcaggaatccaaagg
ataattcagtgtcatggttcctttgcagcagcatcttgcctgatatgtaaatacaaagtt
gactgtgaagctgtaagaggagatatttttaatcaggtggttcctcgatgtcccaggtgc
ccagctgatgagccacttgctattatgaaaccagagattgtcttttttggtgaaaattta
ccagaacagtttcatagagccatgaagtatgacaaagatgaagttgatctcctcattgtc
attgggtcttccctgaaagtaagaccagtagcactaattccaagttccataccccatgaa
gtgcctcagatattaattaatagggaacctttgcctcatctgcattttgacgtagaactt
cttggagactgtgatgtcataattaatgaattgtgtcataggttaggtggtgaatatgcc
aaactatgctgcaaccctgtaaagctttcagaaattactgaaaaacctccacgaacacaa
aaagagttggcacatttgtcagagttgccacccacacctcttaatatttcagaaggctca
agttcaccagaaagaacttcaccaccaaattcttcagttattgtcacacttttagaccaa
gcaacaaagagtaatgttgatgatccagatatgtctgaatcaaaagattgtatggaagaa
cagtcacaggtagtacagacttctactaggagcactgaaagtgttacagaacagttggag
agcccagatttgaagagcattggctccagcactggggagaaggatgaaagaacttcagta
gctgaaaccgtgagaaagtgctggccatccaagctcgcaaaggagcaaattagtaaacgg
cttgatggtaatcaatatctgtttttaccaccaaatcgttacattttccatggtgctgag
gtttattcagactctgaagatgacgtcttatcctctagttcttgtggcagtaatagtgat
agtggaacatgccagagtccaagtttagaagaacccattgaggacgaaagtgaaattgaa
gaattttacaatggtttggaagatgatgctgatattaatgagagagctggaggaacagaa
tttggagctgatggaggtgatcaggaggcagttaatgatgctgtatctatgaaacaggaa
gcaacagacattaactatcagtcaaacaaatcataa
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