Phyllostomus hastatus (greater spear-nosed bat): 123823304
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Entry
123823304 CDS
T07912
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
123823304 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
phas03021
]
123823304 (SETX)
Enzymes [BR:
phas01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
123823304 (SETX)
5.6.2.5 RNA 5'-3' helicase
123823304 (SETX)
Transcription machinery [BR:
phas03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
123823304 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
SEN1_N
AAA_19
UvrD-helicase
AAA_30
AAA_22
nSTAND3
AAA_16
ResIII
NAT10_TcmA_helicase
SLFN-g3_helicase
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
123823304
NCBI-ProteinID:
XP_045701844
LinkDB
All DBs
Position
Unknown
AA seq
2756 aa
AA seq
DB search
MSTCCWCTPGGASTADFLQRYASRAPGGASPAAEEFHTADEDLCYCLECVTEYHRARDEL
PTLHEVLWELETLRLINHFEKSMRGEIEDDDELYIVDSNGEAQLFDFTGQDFENKLRVPI
LEILKYPYLLLHERVNELCVEALCRMEQANCSFQVFEKQPGIYLLLVHPNEMVRRWAILT
AKGLGKVERDDYYDLQEVFTCLFKVIELGLLENPDIYTTSALEKGKLVVLPSHMYDTSSH
KNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHIMERQSQDDSEDPFWPALHCFM
VILDRLGSKVWGQLIDPIEAFQTIINNASYNREIQNIRNSSVRTKSEPESCLDDMVTCSQ
IVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDVGQDMRVHNSTFLWFIPF
VQSLMDLKDLGVVYILEVINHLYFQVKDVLNQPVVTCDKVTEFFSLILVSVIELHRSRKC
LHSLCVNSHRWVEAVVKCARLPTAAFVRSSEKSAGSGSRGPAATSLSLHPMPSNSVQLAC
VQLIRSLLKDGHQLGQQTLCKEFWDKLNLFLRGNLSLGWQLTNQETEALQSCLKQIIRNM
RLRVPQHTALVELAPSCKTPPASCGKEESEEAGKACGKDLRCLESPTFSKPMKADVCQVQ
QRSLVSKVSNAMEEDNGKNYIKDLKLEDHLSAESCLKQSSKNLFPERAQHQVKVCTRKQN
PVKHNCSCAPQNCTSRNSPERGCGQGATMSMRLSADSGADPPEKGSTSKEDFSSQDDVLG
RTSKAKTRAQKSEICAKLSHVIKKQHRKSALVNSTVKLEGDLTESNIENVCSRQGTGGQK
GDSFLHDLTLDPEDIPESKHGGCGSPSSILLKKKQLKKEELGGFSSHENDCQIQDCHFDT
KDLVLFAEGTSTSMHRASPFKDPMSSPESTRKKVSKGADQVSSNLIEQVPSITLQSDILT
DSQVDRDLHKLSLMAQASVTTFPSDSAPKSSPQLQRKVKDKKGFRANQSDVRETCCGQVI
IISDSDDNGDDEGILDLERHWRRDTACAGEECPEPRASMAGADVEGKMTEEERTNSPLEF
EDSDSQVFEFESQRDIFSVWQDQTPDKNSGQGDEKSSCWTPAADTTNDWGYDTDYPMPEE
VTEKESEGTERAQPQSSSTGEESCAVQIKKPKRKKIERPVAKDGLRPSSSVRNEDQSDTG
NESERTENNRSAGARTAPKAGAPRTALVSLKKASPKPCTYSRPVRRAPAPKTARKTHSDA
RRGQNKGSQCISCRTVPFIVPPKKDRQCPEPASTAERLGLKKGPRKRQAFDLSQRSRDCT
ARLRAHGRNVGAIDTGKKTKLISPQAHSVKDKKLLVSQDRQFQRQTRQRSKQNRQGRPDS
TRASAARAGPRAARSSDAAAAEPGRPGCSDRGGTEVVAHSCGNQSLSCASPERGPAKARS
APRAAAGACLSGPCSSPVFNGRRPASEITVSTSEGTPARGDLTGHHLEVAALKKAEPDDD
SDPEGNDLFLTQHDPEDMDLCSQMQDDDDKLIEVVPGENRARGEEDSAHQPRLESLSSAK
CKHQGCVEAVKTQGDCCSKHSAAKAADEDVFRKPGLPPSASRPLRPSTTKIFSSSGTSRT
AHLSKSLESSSALPAVKNKSSGGRSALKAPQPAPPGSPKPAGKGKGLCNIHSSPASPGSP
KSPGEGKGSCSVYSSPAPPGSPKPPGEGKGLRNVLRSPVSPKPLGEVKGLCNVLSPARSN
SSRQAYKLPFGESRPLPSSLDSTSPQSVSDTFVKEVLKWKYEMFVNFDQCGLPASLCQTI
SRPVPVRFQDCNDYFNVFLPLMVVNTFESVAQEWISSPNKEKFYELHLRKFPVEYKKYWE
FVVSLQDCELAKQLHPKENDLVFLVLERRSGEKRDVEGNPVQGPREYHCAYVHKFRRTSA
LRNGKYECFLCIQTQDDLPVNLNEFVKCIVISSLVTTQRKLKAMTLLNGRNQLARAILNP
NPMDFCTKDLLTTTSERIVSDGCVMAGSQKVSCPSTAYLRDFNEEQKKAIETAYAMVKHS
PAVAKICLIHGPPGTGKSKTIVGLLYRLLTERRGHLDENSNAKIKQNRVLVCAPSNAAVD
ELMKKIILEFKEKCKDKKNPMGNCGDINLVRLGPEKAINNEVLKFSLDNQVNHRMKKDLP
SHVQEMHKRKEYLDHQLDELSRQRALCRGGKEMQRRELDERIAHVSKERQELASKIKEVQ
GRPQKTQSIIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQACEVETLTP
LIHRCNKLILVGDPKQLPPTVISLKAQEFGYDQSMMARFCKLLEENVEHNVSGRLPILQL
NMQYRMHPDICLFPSNYVYGKSLRTNRVTETIRCSSEWPFQPYLVFDVGDGLERRDNDSY
VNIQEIKVVIELIKLLKDKRKDVTFRNVGIITHYKAQKMMIQKELDKEFEGKGLAEVDTV
DAFQGRQKDCIIVTCVRANAVQGSIGFLASLQRLNVAITRAKYSLFILGHLRTLMDNQHW
NHLIQDAQRRGAIIKTCDKNYRHDATKILKLKPMLQRSLTHPPALALEGFSLRGGSPSSR
PDEIIKALSASFLNGTAPDPKEAAATAAARDPERPPVKDQPRDPRLLKRMGLSSEAQGKC
LRDPEPSSPQHQGATPPLGEPGFPGSPQVPGSTMEWSTATGSVHRPHAPCEPPAASAAAT
TSVYDQEWGHSHQRDARAFRDWDQEMPSPASHRPKRNSGRDRRPEREDSRSKRRKL
NT seq
8271 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgctggtgcaccccgggcggggcctccactgccgacttcctgcagcgc
tacgcgtccagggccccgggcggcgcgtcccccgcagcagaggagttccacaccgcagac
gaagacctctgctactgcttggagtgtgtgaccgagtaccacagggctcgcgatgagctg
cccaccttgcacgaggttttatgggaactagaaaccttacgtctcataaatcactttgaa
aagtccatgaggggagagatcgaggacgacgacgagttgtacatagtggacagcaacggg
gaggcccagctgttcgacttcactggccaggacttcgagaataagcttcgagttccgatt
cttgaaatcctgaaatacccttacctgcttttacacgagcgtgtcaacgagctgtgtgtg
gaagcgctgtgccggatggagcaggcgaactgctcctttcaggtgtttgagaaacagcct
gggatctacttgttgctggtccatcctaatgaaatggtgcggcgttgggcaatcctgaca
gcaaaaggcttggggaaggtggagcgggacgactactatgacctacaggaggtttttacg
tgcctcttcaaagtcatcgagttggggcttttggagaatccggacatttataccacctct
gccctcgagaaggggaaactggtcgtcctgccctcgcacatgtacgacacgagcagccac
aagaactactggctagggatctgcatgctgctgaccatcctcgaggagcaggccatggac
tcgctgctgctgggctccgacaagcagaacgacttcatgcagtccatactgcacatcatg
gagaggcagtcgcaggatgatagtgaagatcctttctggccagcattgcactgtttcatg
gtgattctggatcgcctggggtccaaggtctggggtcaacttattgatccgattgaggca
tttcagaccattatcaacaatgcaagctacaacagagagatccagaatatccggaacagc
tctgtaaggaccaagtccgaaccggagtcgtgtctggatgatatggtgacttgcagccag
attgtatacaattacaatcctgaaaagaccaaaaaggactcgggctggagatcggccatt
tgcccggactattgcccaaacatgtacgaagaaatggagacattggccagtgtgctccag
tcggatgtcggtcaagacatgcgcgttcacaacagcacgtttctgtggttcatccctttc
gttcagtctctcatggaccttaaggacctgggtgtggtttacatactagaggttattaac
catctgtacttccaagtcaaagatgtcctcaaccaaccagtcgtcacatgtgacaaagtc
actgaatttttttccctgattttggtgtctgtgatcgagctccacagaagcaggaagtgc
ctgcactcgctctgtgtcaactcccatcggtgggtggaggccgtcgtgaagtgtgccagg
ctccccaccgccgcgttcgtgcggagttccgagaagtcggccggcagcggctccagagga
ccagcagcgacatcactgtccctgcatccaatgccgtctaactcggtccagctggcttgt
gtgcagctgattagaagtctccttaaagacggtcatcagcttgggcagcaaactctttgt
aaggaattctgggataaactcaacttattcctgcgaggaaatttatctctaggttggcag
ttgactaatcaggaaaccgaagcgctacagtcttgtttaaagcaaattattagaaacatg
agactcagagtacctcagcataccgctctggtggagctggctccttcctgtaaaactcct
cctgcgtcttgtggtaaagaagaaagtgaagaagcagggaaggcgtgtggaaaagacctg
cgctgtctggaaagcccaacgttttctaaaccgatgaaagctgatgtgtgtcaagtgcaa
cagaggagcctagtaagcaaagtgagtaacgccatggaagaggataatgggaagaattac
ataaaagatttgaaactggaggaccatctgtcagctgagtcatgcttaaagcagagtagt
aaaaaccttttccctgaaagagcccaacatcaagttaaagtatgtacaaggaagcagaat
cctgtaaaacataattgctcatgtgcaccacagaactgtacttcaagaaatagcccggaa
agggggtgtggccaaggagcgactatgtccatgcgcctgtcggctgattccggtgcagat
cctccggagaaggggtccacatcaaaggaggacttctcttcacaggatgatgtccttggc
agaacctcaaaagcaaaaacgagggcacagaaaagtgaaatctgtgctaagttatcacat
gtaataaagaagcaacacaggaaaagtgctttggtcaatagtactgtgaaattagaggga
gacctgacggaatctaacattgagaatgtctgttcaaggcaaggcacaggaggtcagaaa
ggggacagcttcctgcacgatctcactttagaccctgaggatattccagaaagtaaacat
ggagggtgcggatctcctagcagtatattgctgaaaaagaaacaattgaagaaggaagag
ttaggtgggttttcttcccatgaaaacgattgtcaaatacaggactgtcattttgatact
aaagatttggtcttgtttgcagaagggaccagtacttccatgcatagagcatctcctttt
aaagatcctatgagttcacctgaatcaactcgaaagaaagttagcaagggtgctgatcag
gtttcttctaacttgatagaacaggtccctagcatcacccttcagtctgacatcttaaca
gattctcaggtggacagagatctccacaaattatcattgatggctcaagccagtgttacc
acatttccatcagattcagctccaaaaagctcaccccagctacaaagaaaagtaaaagat
aaaaaaggtttcagagccaaccaaagtgatgtcagagaaacctgctgtggacaagtcatc
atcatctcagattccgacgacaatggtgatgatgaaggaatcctggatctggagagacac
tggagacgagatacagcgtgcgctggggaggagtgtcccgagccacgtgcttcgatggct
ggtgcggacgtggaagggaagatgacagaagaagaaaggacaaattcccccttggagttt
gaggactccgattctcaggtgtttgagtttgaaagccaaagggacatattttcagtttgg
caagatcagacaccagacaagaattcaggtcaaggggatgaaaagagttcgtgttggact
cccgcggcagataccaccaatgactggggctatgatacggattaccccatgcccgaggaa
gttactgaaaaagaatcagagggcaccgagcgcgcacaaccacagagcagtagtactggt
gaggaatcctgtgcagttcaaataaaaaaacctaagaggaaaaaaattgaaagaccagtg
gctaaagatggtttaaggccttcatcttctgtcagaaacgaggaccagtctgacactggc
aatgagagtgagcgaactgaaaataacaggagtgcaggcgcaaggaccgctcccaaagca
ggtgctccgagaaccgccttggtttccctgaagaaggcttcgccaaagccttgtacttac
tccagacccgttcggagagccccagctcccaaaactgccaggaagacacattcagacgcc
agaagagggcagaataagggctcccagtgcatcagctgcaggacggtgcccttcatagtg
ccgcccaagaaggaccgccagtgtcccgagcccgcctccaccgcggagcggctcgggctg
aagaagggccctcgcaagcgccaggccttcgacctgtcgcagaggtctcgggactgcaca
gcgcggttacgcgcccacggcagaaacgtcggcgccattgatactggaaaaaagactaaa
ctgatttctcctcaggctcattctgtgaaagataagaaactgctcgtgagtcaagatcgt
cagtttcaaaggcagacgagacagaggtctaaacaaaacaggcaaggacgccctgattct
acacgtgccagtgccgcgagagcgggaccacgggcggctcggagctctgacgcagctgca
gcagagccgggccggccgggttgcagcgacagaggagggaccgaggtcgtggctcacagc
tgtgggaaccagtcgttgagctgcgcgtctcctgaacgaggacccgctaaagcacgatct
gctcctcgggcggctgccggggcttgtctttcgggcccgtgtagttccccagtgttcaat
ggaagacgaccagcgagcgaaatcacggtctccacttccgaaggcactccagctagaggg
gacctgaccggacatcacctagaggtggcagctttgaagaaggcagagcctgacgacgac
agtgacccggagggaaatgatctctttttaacacaacacgatcccgaagatatggacttg
tgttcgcagatgcaggacgatgacgataaactcatcgaagtggttcccggggaaaacaga
gctcggggagaagaggattctgcacaccagcctcggttggagtctctcagtagcgcaaaa
tgtaagcaccagggctgtgtcgaagctgtgaagacccagggcgactgctgctcgaaacac
tccgcggccaaagcggccgacgaagacgtcttccgcaaacctggcttgccaccttctgcc
tctagacctttgagaccttccaccactaagatttttagctcaagtggtacttcacggact
gctcatctctccaagtctttggaaagcagctcagcacttccagctgtaaaaaataagtca
agtgggggacggtctgctttgaaagcaccacagccagcccctccggggtctccgaagcca
gcgggcaaagggaagggattgtgcaacattcattcttctccggcgtctccggggtctccg
aagtcaccgggtgaagggaagggatcgtgcagtgtttattcttctccggcccctccgggg
tctccgaagccaccgggtgaagggaagggtttacgcaacgttcttcggtctccagtgtct
ccaaagccattgggtgaagtgaagggtttgtgcaacgttctttctccagctcgaagtaat
tccagcagacaagcttacaaactgccgtttggtgagagcagacctcttccatcttctctg
gacagcacttcgccgcagtccgtctctgacaccttcgttaaagaggtcttgaagtggaaa
tatgagatgttcgtgaacttcgaccagtgcgggctgccagcaagtctttgtcagaccatc
tcaagacctgtgcctgtcagattccaagattgtaacgattattttaacgttttccttcct
ttgatggtagtgaatactttcgaatcagtagcacaggaatggatcagctctccaaataaa
gaaaaattctatgagttgcatttacgaaaatttcctgtagaatacaaaaaatactgggag
tttgttgtttctcttcaggattgtgaactagctaaacagcttcacccgaaggagaatgac
ttggtgtttttggtccttgaacgacggagtggagagaagagagatgtggaggggaaccct
gtccagggtccccgtgaataccactgcgcttacgtccataaattccgccgcacgtcagcc
ctgcgtaatgggaaatatgagtgtttcctttgcatccagactcaagatgacttgccagtc
aatctgaacgaatttgtaaaatgtattgtaatcagttctctggtaactacgcaaaggaaa
ttgaaagccatgacgttgctgaatggtcggaaccagctggccagagctatcctgaatcca
aaccccatggacttctgtacgaaagatttactgaccacgacatcggagagaattgtgagt
gatggttgtgtgatggcgggaagtcagaaggtgtcctgtccttcgactgcctacctaaga
gatttcaacgaagaacagaagaaggcgatcgaaaccgcctatgccatggtgaaacactcc
ccggcggttgccaagatctgtctcatccacgggccccctgggacggggaagtcgaagacc
atcgtcggcctcctgtaccgcctgctgacggagaggagggggcacttggatgaaaactcg
aacgccaagatcaagcagaaccgcgtgctcgtgtgtgcgccttccaacgcggccgtggac
gagctgatgaaaaagattattcttgaattcaaagaaaagtgtaaagacaagaagaatcct
atgggaaactgtggagatatcaatttagtacgtctggggccagaaaaggctattaataat
gaggtcctaaaattcagtttggacaaccaagtcaaccacagaatgaaaaaagacttacca
tctcacgttcaggagatgcataaaagaaaggagtacctggaccatcagctagatgaactt
tcccgccagcgtgctctctgccgaggtgggaaggaaatgcagaggcgagaattagatgaa
agaattgctcatgtttccaaagaaaggcaggaacttgcttctaaaattaaagaggttcaa
ggacgcccgcagaaaacccagagcatcatcatcctggagtctcacgtcatctgctgcacc
ctgagcacgagcggcggcctgctgctcgagtccgccttccgcggacaggggggcgtcccc
ttcagctgtgtcatcgtcgacgaggcggggcaggcgtgcgaggtcgagaccctcacccca
ctcatccaccgctgcaacaagctgatcctcgtgggcgacccgaagcagctcccccccacg
gtcatctccctgaaggcgcaggagttcggctacgaccagtcgatgatggcccgcttctgc
aagctgctggaggagaacgtggagcacaacgtgagtggtaggctgcccatcctgcagctg
aacatgcagtaccggatgcaccccgacatctgcctcttcccctccaactacgtgtacggc
aagagcctgaggaccaacagggtgacggagaccatccggtgctcgtcggagtggccgttc
cagccctacctcgtgtttgacgtcggagacggcctggagcggcgggacaacgactcttac
gtgaacattcaagaaataaaagtggtcatagagttgatcaaacttctcaaagacaagaga
aaggacgttactttccggaacgttggcatcataacccattacaaggctcagaagatgatg
attcagaaggagttggacaaagaatttgaaggaaaagggctcgcggaagtagataccgtg
gacgcgtttcagggtcgtcagaaagactgtatcattgtcacgtgcgtccgagcgaacgct
gtgcaaggttcaattgggtttctggcgagcttgcagagactgaacgtcgccatcacacga
gccaagtacagcctcttcatcctgggccacctgcggaccttgatggacaatcagcactgg
aaccacctgattcaggacgcacagaggcgcggcgccatcatcaagacctgcgacaaaaac
tatagacacgacgcaacgaagatcctgaaactgaagcccatgctgcagcgaagtctgacc
cacccccccgccctggccctagagggcttcagcctccggggcggctcccccagcagcagg
cctgacgagattatcaaggcgctgtctgcgtctttcctgaacggcacggcccccgaccct
aaggaagctgctgctaccgctgctgccagggaccccgagaggcctccagttaaggaccag
ccgcgggacccacgactgcttaagagaatgggcctgagctctgaagcgcaagggaagtgc
ctgagggatccggagccctcgagcccccagcaccagggagcaacgccccccttgggtgag
cccggcttccctgggagcccccaggtgccaggcagcaccatggagtggtccacagccaca
gggagcgtccacaggccgcacgcgccgtgtgaacctcctgctgccagtgccgccgccacg
acaagcgtgtatgaccaggagtgggggcacagccaccaaagagacgccagggctttcagg
gactgggaccaggagatgcctagccctgcaagccatcgccccaagaggaactcgggccgg
gaccggagaccggagagggaggacagccgctcaaagaggaggaaactgtag
DBGET
integrated database retrieval system
