Phyllostomus hastatus (greater spear-nosed bat): 123823431
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Entry
123823431 CDS
T07912
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas03060
Protein export
phas04141
Protein processing in endoplasmic reticulum
phas04612
Antigen processing and presentation
phas04918
Thyroid hormone synthesis
phas05012
Parkinson disease
phas05014
Amyotrophic lateral sclerosis
phas05020
Prion disease
phas05022
Pathways of neurodegeneration - multiple diseases
phas05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
123823431 (HSPA5)
04141 Protein processing in endoplasmic reticulum
123823431 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
123823431 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
123823431 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
123823431 (HSPA5)
05014 Amyotrophic lateral sclerosis
123823431 (HSPA5)
05020 Prion disease
123823431 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
123823431 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123823431 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
phas03110
]
123823431 (HSPA5)
04131 Membrane trafficking [BR:
phas04131
]
123823431 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
phas04147
]
123823431 (HSPA5)
Enzymes [BR:
phas01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
123823431 (HSPA5)
Chaperones and folding catalysts [BR:
phas03110
]
Heat shock proteins
HSP70 / DNAK
123823431 (HSPA5)
Membrane trafficking [BR:
phas04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
123823431 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
123823431 (HSPA5)
Exosome [BR:
phas04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
123823431 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
123823431 (HSPA5)
Exosomal proteins of colorectal cancer cells
123823431 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
123823431
NCBI-ProteinID:
XP_045702116
LinkDB
All DBs
Position
Unknown
AA seq
654 aa
AA seq
DB search
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEESADKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccctggtggctgcggtgctgctgctgctcggcgcggcgcgggccgaggag
gaggataagaaagaggacgtgggcacggtggtcggcatcgacctagggaccacctactcc
tgcgtcggggtgtttaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgt
atcacgccgtcttatgtggccttcactcccgaaggggagcgtctgatcggcgatgcagcc
aagaaccagctcacctccaaccccgagaacacggtcttcgacgccaagcggctcatcggc
cgcacatggaatgacccgtctgtgcagcaggacatcaagtttctgcctttcaaggtggtt
gaaaagaagactaaaccgtacattcaagtcgatattggaggtggccaaaccaagacattt
gctcctgaagaaatatctgctatggttctcactaaaatgaaggaaacagctgaggcttat
ttgggaaagaaggttacccatgcagttgttactgtaccagcctattttaatgatgcccaa
cgccaggcaaccaaagatgctggaactattgctggattgaatgtcatgaggatcatcaat
gagcctacagcagctgctattgcttatggcctggataaaagggaaggggagaagaacatc
ctggtgtttgatctgggtggtggaacctttgatgtgtctcttctcaccattgacaatggt
gtctttgaagttgtggccactaatggcgatactcatctgggtggagaagactttgaccag
cgtgtcatggaacatttcattaagctctacaagaagaagactggcaaagacgttaggaag
gacaacagagctgtgcagaaactccgacgagaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttctctgag
accctgactcgggccaaatttgaagagctaaacatggacctgttccgttctaccatgaag
cctgtccagaaagtgctggaagattctgatttgaagaaatctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcaacaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcataaacccagatgaagctgtagcgtatggtgctgctgtc
caggccggtgtgctctctggtgatcaagatacaggtgatctggtattgcttgacgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattcctaggaac
actgtggtgcccaccaagaagtcacagatcttctctacagcctctgataatcagccaact
gttacaatcaaggtttatgaaggtgaacggcccctgacgaaagacaatcaccttctggga
acttttgatctgactggaattcctcctgctccccgtggggtcccgcagattgaagtcacc
tttgagatagatgtgaatggtattctccgagtgacagcggaagacaaaggtacgggcaac
aaaaataagatcacaattaccaatgaccagaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgcagagaagtttgctgaagaagacaaaaagctcaaggagcgcattgat
actagaaatgagttggaaagttatgcctattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactttcctctgaagataaggagaccatggaaaaagctgtagaggaa
aagattgaatggctggaaagtcaccaagatgctgacattgaagacttcaaagctaaaaag
aaggaactagaagaaatcgtgcagccaattatcagcaaactctatggaagtgcaggccct
ccccccactggcgaagaggaatcggcagacaaagatgagttgtag
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