Phyllostomus hastatus (greater spear-nosed bat): 123823509
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Entry
123823509 CDS
T07912
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00790
Folate biosynthesis
phas01100
Metabolic pathways
phas01240
Biosynthesis of cofactors
phas01523
Antifolate resistance
phas04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
123823509 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
123823509 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
123823509 (FPGS)
Enzymes [BR:
phas01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
123823509 (FPGS)
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
123823509
NCBI-ProteinID:
XP_045702286
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All DBs
Position
Unknown
AA seq
580 aa
AA seq
DB search
MPGARSQLRAALFLAAVSPFGATPRVAGRRAWSARPAPQEPGMEYQDAVRALNTLQTNAS
YLEEAKRRRGDPPTQLEAMKLYLAQSGLQVEDLDRLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKDSSSCVSMPSYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDSTNIIRKPVVCGVSALGIDHTSLLGDTMEKI
AWQKGGIFKHGVPAFTVLQPDGPLAVLRERAEQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQRKDHQGIGELKASRPSPLGQLPLAPVFQPTPHMRLGLQGTE
WLGRSQVLRRGSLTWYLDGAHTCSSMQACVRWFRHALQRLERPSKGSEVCILLFNSTGDR
DAAALLKLLQPCQFDYAVFCPNLTEVSPMDNADQQNFMVTLDQVLLRCLEHQQHWGRLHE
EPAGLEPVGPGSLLLAPRPPHTHSTSSLVFSCISHALQWISQGRDPVFQTPSPPQGLLAH
PVAASGARVLHEATAVHVLVTGSLHLVGGALKLLEPSLSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgcccggggcgcgcagtcagctgcgcgccgctctcttcctggcagcggtttctccgttt
ggtgcaacgcccagggtcgcggggaggcgagcgtggagtgcaaggcccgcgccgcaggag
ccgggcatggagtatcaggatgctgtgcgcgcactcaacaccctgcagaccaacgccagc
tacctggaggaggcgaagcgccggcggggcgaccccccgacacagctggaggccatgaag
ctgtacttggcacagagtgggcttcaggtggaggacttggatcggctgaacatcatccac
gtcactgggacgaaggggaagggctccacctgtgctttcacggaacggatcctccgaaac
tacggcctgaagacggggttctttagctctccccacctggtgcaggtacgggagcggatc
cgaatcaatgggcagcccatcagccccgagctcttcaccaagcacttctggcgcctctat
catcgcctggaggagaccaaggacagcagcagctgtgtctccatgcccagctacttccgt
ttcctcacgcttatggctttccacgtcttcctccaagagaaggtggacctggccgtggtg
gaagtgggtattggcggggcttacgactctactaacatcatcaggaagcccgtagtgtgt
ggggtctccgctcttggcatcgaccacaccagccttctgggggacacgatggagaagatc
gcgtggcagaaggggggcatcttcaagcacggcgtccctgccttcaccgtgctccagccg
gacggccccctggcggtgctgagggagcgtgcggagcagatctcctgtcccctctacctg
tgtccaccgctggaagccctggaggaaggaggccccccgctgaccctgggcctggaggga
gaacaccagcggtccaatgccgccttggccttgcagctggcccgctgctggctgcagcgg
aaggaccaccaaggcatcggggagctgaaagcgtccaggccaagccccctgggtcagctg
ccgctggcgcccgtgttccagcccacaccccacatgcggctcgggcttcaaggcacggag
tggctgggccgctcgcaggtgctgcggcgtgggtccctcacctggtacctggacggcgcg
cacacctgcagcagcatgcaagcctgcgtacgctggttcagacacgcgctgcagcgcctg
gagaggcccagcaaagggtctgaagtgtgcatcttgctcttcaactccaccggggaccgg
gatgctgccgccctgctgaagctgctgcagccctgccagtttgactatgctgttttctgc
cctaacctgacagaggtgtcgcccatggacaacgcagaccagcagaacttcatggtgacc
ctggaccaggtgttgctccgctgcttggagcaccagcagcactggggccgcctgcacgag
gagccggccggcctggagcctgtggggcctggatccctgctcctggcaccccgccctccc
cacacccacagcaccagctccctcgtcttcagctgcatctcccacgctctgcagtggatc
agtcagggccgggacccggtctttcagacacccagtcccccgcagggccttctcgcccac
cccgtggcagccagcggggccagagtgctccatgaggccactgccgtccacgtgctggtc
accgggagcctgcacctggtgggcggcgccctgaagctgctggagccctccctgtcccag
tag
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