Phyllostomus hastatus (greater spear-nosed bat): 123824590
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Entry
123824590 CDS
T07912
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas00230
Purine metabolism
phas01100
Metabolic pathways
phas04927
Cortisol synthesis and secretion
phas04934
Cushing syndrome
phas05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
123824590 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
123824590 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
123824590 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123824590 (PDE8B)
Enzymes [BR:
phas01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
123824590 (PDE8B)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PDE8
PAS_8
DHH
JetB
Motif
Other DBs
NCBI-GeneID:
123824590
NCBI-ProteinID:
XP_045703780
LinkDB
All DBs
Position
Unknown
AA seq
887 aa
AA seq
DB search
MDHPRCWPSTRQSGVIYCRDSDESNSPCHITSVSQGPAAPQPGLFVQTDAADAVPRSRAS
GPPSAARVRRARRAELGSGSSTDSAAPTGTTCRGRRRHCCSSAEAETQTNYSNVKQVSPA
EVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGFRCNIARTPESALECFLDKHHE
IIVIDHRQSRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDHEEASVLPLLHAGFNRRF
VENSSITACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDEHVIQYVNPAF
ERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQH
VKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTESHSLRYKNRRRESI
DVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRV
LEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPI
TINDVPPCIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLR
AWLQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVD
HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDNKCNIFKNIDRNHYRTLRQ
AIIDMVLATEMTKHFEHVNKFVNSINKPMAAETEGSDCECNPIGKNLPENQILIKRMMIK
CADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFID
YFITDMFDAWDAFAHLPALMQHLANNYKHWKTLDDLKCKSLRLPSDN
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atggaccatcctcgctgctggccaagcacccgccagagcggcgtgatctactgtcgggac
tcggacgaatccaactcgccctgccatatcaccagcgtgtcgcagggccccgcagccccc
cagcccggcctcttcgtccagaccgacgccgccgacgccgtaccccggagccgcgcgtcc
ggaccccccagcgccgctcgggtccgtagggcccgccgcgcagagctgggcagtggcagc
agcaccgactctgcggcccccacggggaccacctgcaggggccggaggcgccactgctgc
agcagcgcggaggccgagacccagaccaactactccaacgtcaagcaggtttctcctgcg
gaggtacgcattgggcccatgagactgacgcaggatcctatccaggttctgctgatcttt
gccaaagaggacagtcagagcgacgggttctggtgggcctgcgacagagccggcttccgg
tgcaacatcgcccggactccggagtcagccctggagtgctttctagataaacatcatgaa
attatcgtcattgatcacagacaaagtcgaaactttgatgcagaagctgtgtgcaggtcg
atccgggccacaaacccctcggagcacacggtgatcctcgcggtggtttcacaagcatcg
ggcgaccacgaagaggcctcagtcctccctcttcttcatgcaggcttcaacaggagattt
gtggagaatagcagcatcactgcttgctataatgaacttattcaaatagaacacggggaa
gttcgctcacagttcaaattacgggcctgtaattcagtgtttacagcattagaccactgc
cacgaagccatagaaataacaagcgatgagcatgtgattcagtatgtcaacccagccttc
gaaaggatgatgggctaccacaagggcgagctcctggggaaagaactcgcggagctgccc
aagagcgacaagaaccgggcagacctcctcgacaccatcaacacgtgcatcaagaagggc
aaggaatggcaaggggtttactatgccagacggaagtccggggacagcatccaacagcac
gtgaagatcacccccgtgattggccaaggagggaaaattaggcattttgtctccctcaag
aaactgtgttgtaccactgacaataataagcagattcacaagattcatcgtgattcagga
gacaattctcagacagagtcccattcactcagatacaagaacaggaggagagagtccatc
gatgtgaaatcaatatcatctcgaggcagtgatgcaccgagcctccagaaccgccgctat
ccgtctatggccaggatccactccatgaccatcgaggcgcccatcacgaaggttataaat
ataatcaatgcggcccaagaaaacagccccgtcacagtagcggaagccttggacagagtt
ttagaaattttacggaccacggaattgtactcccctcagctgggtaccaaagatgaagat
cctcacaccagcgatctcgtcggaggcctgatgactgatggcctgcgaaggttgtccgga
aatgagtacgtgttcactaagaacgtgcaccagagtcacagtcacctggcgatgccaata
accatcaacgatgtccccccttgtatcgcccagttactggataatgaggaaagttgggag
ttcaacatctttgagttggaagctgttacacataaaaggccactggtttacctgggctta
aaggtcttttcccggtttggagtctgtgagtttttacactgttctgaaaccactcttcgg
gcctggctccaagtgatcgaggccaactaccactcctccaacgcgtaccacaactccacc
catgccgccgacgtgctgcacgccaccgccttcttcctcgggaaggaacgagtgaagggc
agcctcgaccagctggatgaggtggcagcactgatcgctgccacagtccatgacgtggac
cacccgggaaggaccaactctttcctctgcaacgcaggcagtgaacttgctgtgctctac
aatgacaccgccgtcttggagagtcaccacacagccctggccttccagctgacggtgaag
gacaacaaatgcaacattttcaagaatattgacaggaaccattatcgaacgctgcgccag
gctattattgacatggtcttagcaacagagatgacaaaacactttgaacatgtgaacaaa
tttgtgaatagcatcaacaagccgatggcagctgagaccgagggcagtgactgtgaatgc
aaccctattgggaagaacttacctgaaaaccaaatcctgatcaagcgcatgatgattaag
tgtgctgacgtggccaacccatgccgccccctggacctgtgcatcgaatgggcagggagg
atctccgaggaatacttcgcacagaccgatgaagagaagagacagggactacctgtggtg
atgccagtgtttgaccggaatacctgtagcatccccaagtcacaaatttccttcattgac
tacttcataacagacatgttcgatgcttgggatgcctttgcacacctgccagccctaatg
caacacctggccaacaactacaagcactggaagacattagatgacctgaagtgcaagagt
ctgaggctcccatccgacaactga
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