KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123827255
Entry
123827255         CDS       T07912                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521  EGFR tyrosine kinase inhibitor resistance
phas04012  ErbB signaling pathway
phas04062  Chemokine signaling pathway
phas04110  Cell cycle
phas04150  mTOR signaling pathway
phas04151  PI3K-Akt signaling pathway
phas04310  Wnt signaling pathway
phas04340  Hedgehog signaling pathway
phas04360  Axon guidance
phas04390  Hippo signaling pathway
phas04510  Focal adhesion
phas04517  IgSF CAM signaling
phas04518  Integrin signaling
phas04519  Cadherin signaling
phas04550  Signaling pathways regulating pluripotency of stem cells
phas04657  IL-17 signaling pathway
phas04660  T cell receptor signaling pathway
phas04662  B cell receptor signaling pathway
phas04722  Neurotrophin signaling pathway
phas04728  Dopaminergic synapse
phas04910  Insulin signaling pathway
phas04916  Melanogenesis
phas04917  Prolactin signaling pathway
phas04919  Thyroid hormone signaling pathway
phas04931  Insulin resistance
phas04932  Non-alcoholic fatty liver disease
phas04934  Cushing syndrome
phas04935  Growth hormone synthesis, secretion and action
phas04936  Alcoholic liver disease
phas05010  Alzheimer disease
phas05020  Prion disease
phas05022  Pathways of neurodegeneration - multiple diseases
phas05135  Yersinia infection
phas05160  Hepatitis C
phas05162  Measles
phas05163  Human cytomegalovirus infection
phas05165  Human papillomavirus infection
phas05167  Kaposi sarcoma-associated herpesvirus infection
phas05200  Pathways in cancer
phas05210  Colorectal cancer
phas05213  Endometrial cancer
phas05215  Prostate cancer
phas05217  Basal cell carcinoma
phas05224  Breast cancer
phas05225  Hepatocellular carcinoma
phas05226  Gastric cancer
phas05415  Diabetic cardiomyopathy
phas05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:phas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    123827255 (GSK3B)
   04310 Wnt signaling pathway
    123827255 (GSK3B)
   04340 Hedgehog signaling pathway
    123827255 (GSK3B)
   04390 Hippo signaling pathway
    123827255 (GSK3B)
   04151 PI3K-Akt signaling pathway
    123827255 (GSK3B)
   04150 mTOR signaling pathway
    123827255 (GSK3B)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123827255 (GSK3B)
   04518 Integrin signaling
    123827255 (GSK3B)
   04519 Cadherin signaling
    123827255 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    123827255 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123827255 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    123827255 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    123827255 (GSK3B)
   04657 IL-17 signaling pathway
    123827255 (GSK3B)
   04662 B cell receptor signaling pathway
    123827255 (GSK3B)
   04062 Chemokine signaling pathway
    123827255 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123827255 (GSK3B)
   04917 Prolactin signaling pathway
    123827255 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    123827255 (GSK3B)
   04919 Thyroid hormone signaling pathway
    123827255 (GSK3B)
   04916 Melanogenesis
    123827255 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    123827255 (GSK3B)
   04722 Neurotrophin signaling pathway
    123827255 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    123827255 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123827255 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123827255 (GSK3B)
   05225 Hepatocellular carcinoma
    123827255 (GSK3B)
   05226 Gastric cancer
    123827255 (GSK3B)
   05217 Basal cell carcinoma
    123827255 (GSK3B)
   05215 Prostate cancer
    123827255 (GSK3B)
   05213 Endometrial cancer
    123827255 (GSK3B)
   05224 Breast cancer
    123827255 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    123827255 (GSK3B)
   05162 Measles
    123827255 (GSK3B)
   05163 Human cytomegalovirus infection
    123827255 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123827255 (GSK3B)
   05165 Human papillomavirus infection
    123827255 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    123827255 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123827255 (GSK3B)
   05020 Prion disease
    123827255 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    123827255 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123827255 (GSK3B)
   05415 Diabetic cardiomyopathy
    123827255 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123827255 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    123827255 (GSK3B)
   04931 Insulin resistance
    123827255 (GSK3B)
   04934 Cushing syndrome
    123827255 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123827255 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:phas01001]
    123827255 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:phas03036]
    123827255 (GSK3B)
Enzymes [BR:phas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     123827255 (GSK3B)
Protein kinases [BR:phas01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   123827255 (GSK3B)
Chromosome and associated proteins [BR:phas03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    123827255 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 123827255
NCBI-ProteinID: XP_045707686
LinkDB
Position
Unknown
AA seq 433 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRVQ
TNNAASASASNST
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggatggcagtaaggtgaccacagtg
gtggcaactcctgggcagggtccagacaggccacaagaagtcagctatacagacactaaa
gtgattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgattcgggagaa
ctggttgccatcaagaaagtattgcaggacaagagatttaagaaccgagagctccaaatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactcaagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgcttcctgtgatctatgtcaagtta
tatatgtatcagctgtttcgaagtttagcctatattcattcctttggaatctgccatcgg
gatattaaaccacagaacctcttgttggaccctgatacagctgtcttaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgcaggctgtgtgctggctgagctgttgctaggacaaccaatatttccaggggat
agtggtgtggatcagttggtggaaataatcaaggtcctggggacaccaacaagggagcaa
attagagaaatgaacccaaactacacagaattcaaatttcctcaaattaaggcacaccct
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cgaactccaccagaggcaattgcactgtgtagccgtctgctcgagtacacaccaactgcc
cgattgacaccactggaagcttgtgcacattcattttttgatgaattacgggacccaaat
gtcaaactaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagaactg
tcaagtaatccacctctagctacaatccttattcctcctcatgctcggattcaagcagct
gcttcaacccctacaaatgccacagcagcctcagatgctaatgctggagaccgtgtacag
accaataacgctgcttctgcatcagcttccaactccacctga

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