Phyllostomus hastatus (greater spear-nosed bat): 123828369
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Entry
123828369 CDS
T07912
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas04217
Necroptosis
phas04380
Osteoclast differentiation
phas04620
Toll-like receptor signaling pathway
phas04621
NOD-like receptor signaling pathway
phas04630
JAK-STAT signaling pathway
phas04658
Th1 and Th2 cell differentiation
phas04659
Th17 cell differentiation
phas05145
Toxoplasmosis
phas05160
Hepatitis C
phas05161
Hepatitis B
phas05162
Measles
phas05164
Influenza A
phas05165
Human papillomavirus infection
phas05167
Kaposi sarcoma-associated herpesvirus infection
phas05168
Herpes simplex virus 1 infection
phas05169
Epstein-Barr virus infection
phas05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
123828369 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
123828369 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
123828369 (TYK2)
04621 NOD-like receptor signaling pathway
123828369 (TYK2)
04658 Th1 and Th2 cell differentiation
123828369 (TYK2)
04659 Th17 cell differentiation
123828369 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
123828369 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
123828369 (TYK2)
05160 Hepatitis C
123828369 (TYK2)
05171 Coronavirus disease - COVID-19
123828369 (TYK2)
05164 Influenza A
123828369 (TYK2)
05162 Measles
123828369 (TYK2)
05168 Herpes simplex virus 1 infection
123828369 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
123828369 (TYK2)
05169 Epstein-Barr virus infection
123828369 (TYK2)
05165 Human papillomavirus infection
123828369 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
123828369 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123828369 (TYK2)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123828369 (TYK2)
Protein kinases [BR:
phas01001
]
Non-receptor tyrosine kinases
JAK family [OT]
123828369 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
FERM_C_FAK1
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
123828369
NCBI-ProteinID:
XP_045709221
LinkDB
All DBs
Position
Unknown
AA seq
1177 aa
AA seq
DB search
MPLCHCGATGRGSKPNGDEAQLMTTRGGLKVLLHWAGPDSREPWVTFSEATLTAEEVCIH
IAQKVGITPPCFNLFALFDAQAQVWLPPNHILEVSRDTNLMLHFRMRFYFRNWHGMNLQE
PAVYRCGPPGAETSSEQAEQGVPLLDSASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
KNESLGMAFLHLCHLALCRGISLEKVAKKISFKDCIPRSFREEIQQYNVFTQLRLWIIFH
RFLQAFQPGRLSQQVIMVKYLATLEQLAPRFGTERVPVCHLELVPQATGEHCYIQDSGQA
PADPKPESAVESLTHEVLVTGTGGIQWRPVQTKGPRSSRSPRAGSSGKKAKAQELGEQPV
DRPQEAPWAYFCDFQDITHVVLRERHASIHCQDKSLELTLPSRAIALSLVSLVDGYFRLT
ADSNHYLCHEVAPPRLVMSIQDGIHGPLLEPYVLAKLQPEGGLYLIHWSTTHFDRLILTV
AQQDQAPGMQCLRLRKFPIELSAGAFSLESWDRSFPSVRELRATLQGCSLQAGDNCFSLR
HCCLPRPGEISNLIIMRGPRASTRSLNLSQLSFHWICQDDITQLSHLGQGTRTNVYEGLL
RVGGGGPEEDKADGDPASLGEDRGQELRVVLKVLDPSHHDIALAFYETASLMSQVSHVHL
TFIHGICVHSSKNIMVTEYVEHGPLDVWLRRERGRVPVAWKVAVAQQLASALSYLEDKSL
AHSNVCGRNILLARVGLAEGTSPFIKLSDPGVGLGALSREERVERIPWMAPECMSGGANS
LSTAADKWGFGATLLEICFDGEAPLQDRSPSEKECFYQKRHQLPEPACPELATLTSQCLT
YEPAQRPSFRTILRDLTHLQLQNLSAVLHVNPTSPASDPTIFHKRYLKKIRDLGEGHFGK
VSLYCYDPTNEGTGEMVAVKALKAGCSPQLHTGWRREIDILRTLYHEHIVKYKGCCEDQG
EKAMHLVMEYMPLGSLRDYLPRHSIGLAQLLLFAQQICEGMAYLHMQHYVHRDLAARNVL
LDNDSLVKIGDFGLTKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDIWSFGVT
LYELLTYCDSSQSPPSKFIELIGPTQGQMTVLRLTELLERGERLPRPEKCPYEVYLLMKN
CWEAEASFRPTFQNLVPILKTAHEKYRGQAPSVFSVC
NT seq
3534 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattgtggggccaccggcaggggcagcaagcccaatggggatgaagct
cagctcatgaccaccagaggaggcctgaaggtgctcctgcactgggctggccctgacagc
agggagccctgggtcactttcagcgaggccacactgaccgcagaggaggtctgcattcac
attgcacaaaaagtcggcatcactccaccctgcttcaatctctttgccctctttgatgcc
caggcccaggtctggctgcccccaaaccacattctggaggtctccagagacacaaatttg
atgttgcacttccgcatgaggttttatttccggaactggcatggcatgaatcttcaggag
ccagctgtgtaccgctgtgggcccccaggggccgagacttcatcagaacaggcagaacag
ggcgtgccgctcctggactcagcctcctttgagtacctctttgagcagggtaagcatgag
tttgtgaatgatgtggcatcactgtgggagctgtcgagtgaggaggagatccaccacttt
aagaatgagagcctaggcatggcctttctgcacctctgccacctcgctctctgccgcggt
atttccctggagaaggtggccaagaagatcagcttcaaggactgtatcccacgctccttc
cgggaggagatccaacagtacaacgtgttcacacagctacgcctgtggatcatcttccac
aggttcctgcaggccttccagccaggccgcctttcccagcaggtcatcatggtcaagtac
ctggccacactcgagcagctggcaccccgcttcggcacggagcgtgtgcctgtgtgccac
ctagaactggtacctcaggccacaggggagcactgctacatccaggacagtgggcaggcc
cctgcagaccccaagcccgagtctgcggtcgaatcccttacccatgaggtgctggtgact
ggcactggcggcatccagtggcggccagtacagacaaagggcccccgcagcagcaggagt
cctcgtgccggctcatctgggaagaaagccaaggcccaagagttgggtgagcagcctgtg
gacaggccacaggaggcgccgtgggcctacttctgtgacttccaggacatcacccatgtg
gtgctaagagaacgccatgccagcatccactgccaggacaagagcctggagctgaccctg
ccttcccgggccatcgccctgtccttggtgtcactggtggatggatacttccgcctgacg
gccgactccaaccactacctgtgccacgaggtggctcctccacggctggtgatgagtatc
caggatggcatccacggacccctgctggagccgtatgtgctggccaagctgcagccagag
ggtggcctttatctcatccactggagcaccacccactttgaccgcctcatcctcacagtg
gcccagcaggaccaggcccctggcatgcagtgtttgcgcctgcgcaagttccccattgag
ctgtctgcaggggccttcagcctggagagctgggaccggtccttccccagtgtgcgggag
ctgcgggccaccctgcagggctgctctctgcaggccggtgacaactgcttctccctgcgc
cactgctgcctgccaagaccaggagagatctccaacctcatcattatgcggggacctcgg
gccagcaccaggtctctcaacctcagccagctcagcttccactggatctgccaggatgac
atcacccagctgtcccacttgggccagggcacaaggaccaatgtgtatgaaggcctcttg
cgagtcgggggcggaggccctgaggaggacaaggcagacggggaccccgcctcactcggt
gaggaccgtgggcaggagctacgagtggtactgaaggtgctggaccccagtcaccatgac
attgccctggccttctatgagacggccagcctcatgagccaggtgtcccatgtgcacctg
accttcatccacggtatctgcgtgcacagctccaaaaatatcatggtgaccgagtacgtg
gagcatggacccctggacgtgtggctgcgacgggagaggggccgtgtgcctgtggcctgg
aaggtggcagtggcccagcagctggccagtgccctcagctacctggaggacaagagcctg
gctcacagtaacgtgtgtggccggaacatcctgctggcacgtgtggggctggcggagggc
accagcccgttcatcaaactgagcgaccctggcgtgggcctgggtgccctttccagggag
gagcgggtagagcggatcccctggatggcccccgagtgcatgtctggtggggccaacagc
ctgagcaccgccgctgacaagtggggctttggtgccactcttctggagatctgcttcgat
ggggaggcccccctgcaggaccgcagtccctctgagaaagagtgcttctaccagaagcgg
caccaactgcctgaacccgcatgcccggagctagccacactcaccagccagtgcctgacc
tatgagccagcccagcggccttccttccgcaccatccttcgtgacctcactcaccttcag
ctccaaaatctttcggcagtcctgcatgtgaacccaacctcaccagcatcagaccccact
attttccacaagcgctatttgaaaaagatccgggatctgggtgagggccactttggcaag
gtcagcctgtactgctatgacccaaccaacgaaggcactggtgagatggtggccgtgaag
gctctcaaggcgggctgcagccctcagctccacactggctggaggcgggagattgacatc
ctgcgcacactctaccatgagcacattgtcaagtacaagggctgctgtgaggaccaaggt
gagaaagcgatgcaccttgtcatggagtacatgcccctgggcagcctccgagactacctg
ccccggcacagcatagggctggcccagctgctgctgtttgcgcagcaaatctgcgagggc
atggcctacctgcacatgcagcactatgtccaccgagacctggctgcccgcaacgtgctg
ctggacaacgacagcctggtcaagattggggactttggcctcaccaaggctgtgcctgaa
ggccacgagtactaccgcgtgcgcgaggatggggacagccctgtgttctggtatgccccc
gagtgcctgaaggagtgtaagttctactatgcatctgatatctggtcctttggagtcacc
ctgtatgaactgctgacctactgtgactccagccaaagccccccctcgaaattcatcgag
ctcataggccccacccaggggcagatgacagtactgaggctcactgagctgctggaacga
ggggagaggctgccaaggccagaaaaatgtccctatgaggtctatctcctcatgaagaac
tgctgggaggcagaggcctcatttcgcccaaccttccagaacctcgtacccatcctgaaa
acggcccatgagaaataccggggccaggccccctcggtgttcagtgtctgctga
DBGET
integrated database retrieval system
