Phyllostomus hastatus (greater spear-nosed bat): 123829298
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Entry
123829298 CDS
T07912
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
phas
Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas01521
EGFR tyrosine kinase inhibitor resistance
phas01522
Endocrine resistance
phas04012
ErbB signaling pathway
phas04066
HIF-1 signaling pathway
phas04140
Autophagy - animal
phas04150
mTOR signaling pathway
phas04151
PI3K-Akt signaling pathway
phas04152
AMPK signaling pathway
phas04211
Longevity regulating pathway
phas04213
Longevity regulating pathway - multiple species
phas04350
TGF-beta signaling pathway
phas04371
Apelin signaling pathway
phas04666
Fc gamma R-mediated phagocytosis
phas04714
Thermogenesis
phas04910
Insulin signaling pathway
phas04931
Insulin resistance
phas05163
Human cytomegalovirus infection
phas05165
Human papillomavirus infection
phas05170
Human immunodeficiency virus 1 infection
phas05200
Pathways in cancer
phas05205
Proteoglycans in cancer
phas05207
Chemical carcinogenesis - receptor activation
phas05210
Colorectal cancer
phas05212
Pancreatic cancer
phas05221
Acute myeloid leukemia
phas05224
Breast cancer
phas05225
Hepatocellular carcinoma
phas05226
Gastric cancer
phas05231
Choline metabolism in cancer
phas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
phas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
123829298 (RPS6KB2)
04066 HIF-1 signaling pathway
123829298 (RPS6KB2)
04151 PI3K-Akt signaling pathway
123829298 (RPS6KB2)
04152 AMPK signaling pathway
123829298 (RPS6KB2)
04150 mTOR signaling pathway
123829298 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
123829298 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
123829298 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
123829298 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
123829298 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
123829298 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123829298 (RPS6KB2)
05205 Proteoglycans in cancer
123829298 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
123829298 (RPS6KB2)
05231 Choline metabolism in cancer
123829298 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123829298 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
123829298 (RPS6KB2)
05212 Pancreatic cancer
123829298 (RPS6KB2)
05225 Hepatocellular carcinoma
123829298 (RPS6KB2)
05226 Gastric cancer
123829298 (RPS6KB2)
05221 Acute myeloid leukemia
123829298 (RPS6KB2)
05224 Breast cancer
123829298 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
123829298 (RPS6KB2)
05163 Human cytomegalovirus infection
123829298 (RPS6KB2)
05165 Human papillomavirus infection
123829298 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
123829298 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123829298 (RPS6KB2)
01522 Endocrine resistance
123829298 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phas01001
]
123829298 (RPS6KB2)
Enzymes [BR:
phas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
123829298 (RPS6KB2)
Protein kinases [BR:
phas01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
123829298 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Motif
Other DBs
NCBI-GeneID:
123829298
NCBI-ProteinID:
XP_045710796
LinkDB
All DBs
Position
Unknown
AA seq
481 aa
AA seq
DB search
MAAVFDLDLETEEDSEGEGEPEYPADVCPLAESRAAGLEPVGHYEEVELTETSVNPGPER
IGPHCFELLRVLGKGGYGKVFQVRKVQGTNVGKIYAMKVLRKAKIVRNAKDTAHTRAERN
ILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLGEITLA
LGHLHAQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGTVTHTFCGTIEYMAPEIL
VRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLALPPYLTPDARDLVK
KFLKRNPSQRIGGGPGDAADVQRHPFFRHINWDDLLARRVDPPFKPCLSEEDVSQFDPRF
TRQTPVDSPDDAALSESANQAFLGFTYVAPSVLDSIREGFSFQPKLRSPRRLNSSPRTPV
SPLKFSPFEGFRPSPGPPEPMEPPLPPLVPPPPPPSSTVPLPIRPPSGTKKSKRGRGRPG
R
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgacctggatctggagacggaggaagacagcgagggcgagggcgag
ccggagtaccctgcggacgtgtgtccccttgccgagtcgagggcggctggcctggagccc
gtgggacactacgaggaggtggagctgaccgagaccagtgtgaaccctggccctgagcgc
atcgggccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaaggtg
ttccaggtgcgaaaggtgcagggcaccaacgtgggcaaaatatatgccatgaaagtcctg
aggaaggccaaaattgtgcgcaacgccaaggacacggcgcacactcgggccgagcggaac
attctggagtctgtgaagcacccgttcattgtggagctggcctacgccttccagactggc
ggcaaactctacctcatccttgagtgcctcagcggcggtgagctcttcacgcacttggag
cgagagggcatcttcctggaggacacggcctgcttctacctgggggagatcacactggcc
ctgggccacctgcacgcccagggcatcatctaccgggacctcaagcccgagaacatcatg
ctcagcagccagggccacatcaaactgacagactttgggctctgcaaggagtcgatacat
gagggcaccgtcacccacaccttctgtggcaccattgagtacatggcccctgagattctg
gtgcgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtacgac
atgctcactggatcgccacccttcactgcagagaaccgcaagaaaaccatggacaagatc
atcaaagggaagctggcgctgcccccgtacctcaccccggacgcccgggacctcgtcaaa
aagtttctgaagcggaaccccagccagcggattgggggcggcccaggggatgctgctgac
gtgcagaggcacccctttttccggcacattaactgggacgacctcctagcccgccgtgtg
gacccccctttcaagccctgtctgtcggaggaggacgtgagccagttcgacccccgcttc
acgcggcagacgccagtggacagtccggacgacgcggccctcagcgagagcgccaaccag
gccttcctgggcttcacctacgtggcgccctctgtcctggacagcatccgggagggcttc
tccttccagcccaagctgcgctcccccaggcgcctcaacagcagcccccggacccccgtc
agccccctgaagttctcaccctttgaggggtttcggcccagccccggaccaccggagccc
atggagccccctctgcctcctctggtgccaccaccgccaccgccctcaagcactgtcccc
ctgcccatccgacccccctcagggaccaagaagtccaagaggggccgtgggcgccctggg
cgctag
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