| Entry |
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| Symbol |
TOP2B
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| Name |
(RefSeq) DNA topoisomerase 2-beta isoform X1
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| KO |
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| Organism |
phas Phyllostomus hastatus (greater spear-nosed bat)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:phas00001]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
123830810 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:phas03032]
123830810 (TOP2B)
03036 Chromosome and associated proteins [BR:phas03036]
123830810 (TOP2B)
Enzymes [BR:phas01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
123830810 (TOP2B)
DNA replication proteins [BR:phas03032]
Eukaryotic type
DNA Topoisomerases
123830810 (TOP2B)
Chromosome and associated proteins [BR:phas03036]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
123830810 (TOP2B)
Centrosome formation proteins
Centriole proteins
123830810 (TOP2B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1624 aa
MAKAGGGGGAGAGGNGALTWVTLFDQNNAVKKEESETANRNDSSKKLSVERVYQKKTQLE
HILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKN
MTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGG
RNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQP
DLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDE
TGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVV
KKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKA
ASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTE
GDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKS
YDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKAS
KNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYA
GPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINK
ELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGE
QALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSPLARRLFPAV
DDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLD
GLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLE
PMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMV
LFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQG
KIAIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEESQNQHDDSSSDSGTPSGPD
FNYILNMSLWSLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQ
EREDMMAGMAGKAVKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKK
GDLDTTAVKVEFDEEFSGTPVEGTGEEALIQSVPVNKGPKPKREKKEPGTRVRKRRTPTS
SGKPGAKKMKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDD
DADDNDDDNNDLEELKVKASPITNDGDDEYVPSDGLDKDEYTFSPGKSKATPEKSSHDKK
SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS
SDTTPKPKRTPKQKKIETINSDSDSEFGIPKKTTTPKGKGRGARKRKASGSENEGDYNPG
RKTSKPPSKKPKKTSFDQDSDVDIFPPDFTSEPPSLPRTGRARKEVKYFAESDDEEDVDF
AMFN |
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| NT seq |
4875 nt +upstreamnt +downstreamnt
atggccaaggcgggcggcggtggcggcgcgggagccggcggcaacggggcactgacctgg
gtgactctttttgatcagaacaatgctgtaaaaaaagaagagtcggaaactgcaaacaga
aatgattcttcaaagaagttgtctgttgagagagtatatcagaaaaagacacaacttgaa
cacattctccttcgtcctgacacatacatcgggtcagtggagccattgacacagctaatg
tgggtgtatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggttta
tacaagatctttgatgaaatcttggttaatgcagctgacaataaacagagggataagaac
atgacctgtattaaagtttctattgatcccgaatctaacattataagcatttggaataat
gggaaaggcattccagtagtagaacataaagtagagaaagtttatgttcctgcattaatt
tttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggt
cgtaatggttatggtgcaaaactttgtaatattttcagtacaaagttcacagtagaaact
gcttgcaaagaatacaaacatagttttaaacagacatggatgaataatatgatgaagact
tctgaagccaaaattaaacattttgatggtgaagattacacatgtataacattccaacca
gatctgtccaaatttaagatggaaaaacttgataaggacattgtggccctcatgaccaga
agagcttatgatttggctggttcctgcaaaggggtcaaggtcatgtttaatggaaagaaa
ttgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaaattggatgaa
actggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctt
acgttgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaacaacaaaa
ggtggacgtcatgtggattatgtagtagatcaagttgttggtaaattgattgaagtagtc
aagaaaaagaacaaagctggtgtatcagtgaaaccgtttcaagtaaaaaaccatatatgg
gtttttattaattgccttatcgaaaacccaacttttgattctcagactaaggaaaacatg
actctgcagcccaaaagttttgggtccaaatgccagctatcagaaaaatttttcaaagca
gcttctaactgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagact
cagctgaacaagaagtgttcgtcagtaaaatatagtaaaatcaaaggtattcccaaactg
gatgatgcaaatgatgctggtggcaaacattccctggagtgtacactgatactaacagag
ggagactctgccaaatcgctggcagtatctggattaggtgtgattggacgagacagatat
ggagtctttccactcaggggaaaaattcttaatgtccgagaagcctctcataaacaaatc
atggaaaatgcagaaataaataatattattaaaatagttggcctacagtacaagaaaagt
tatgatgatgcagaatctctgaaaactttacgctatggaaagattatgattatgactgat
caggatcaagatggatctcacataaaaggcctgcttattaattttatacaccacaattgg
ccatcacttttgaagcatggttttcttgaagagttcattactccaattgtaaaggcaagc
aaaaacaagcaggaactttccttctacagtattcctgaatttgatgagtggaaaaaacat
atagaaaaccagaaagcctggaaaataaaatattacaaagggttgggtaccagtacagct
aaagaagcaaaggaatattttgctgacatggaaaggcaccgcatcttgtttagatatgct
ggtcctgaagatgatgctgccattacattggcattcagtaaaaagaagattgatgacaga
aaagaatggttaacaaattttatggaagatcggaggcagcgtaggttacatggattacca
gagcaatttttatatggtacagcaacaaagcatttgacatacaatgatttcatcaacaag
gaattgattctcttctcaaactcagacaatgaaagatctataccttctcttgttgatggc
tttaaaccaggccaacgaaaagttttatttacctgtttcaaaaggaatgataaacgtgaa
gtaaaagttgcccagttggctggatctgttgccgagatgtctgcttatcatcatggagaa
caagcattaatgatgactattgtgaatttggctcagaactttgtgggaagtaacaacatt
aacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgca
agccctcgttacattttcaccatgttaagccctttagcaagacggctttttcctgctgtg
gatgacaacctgctaaaattcctttatgatgataatcaacgggtggagcctgagtggtat
attcccataattcccatggttttaataaatggtgctgagggcattggtactggatgggct
tgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagat
ggcttggatcctcatcccatgcttccaaactacaaaaactttaaaggaacaattcaagaa
ctcggtcagaaccaatatgcagtcagtggtgaaatatttgtggtggatagaaacacagta
gagattacagagcttccagttaggacttggacacaggtatacaaagaacaggttttagaa
cctatgctaaatggaacagataaaacaccagcattaatttctgattataaagaatatcat
actgatacaactgtgaaatttgtggtgaaaatgaccgaagagaaattagcacaagcagaa
gctgctggattgcataaagtttttaaacttcaaactactcttacttgtaattccatggta
ctctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattttgaaagaa
ttctttgatttacggttaagctattatggtttacgtaaggagtggcttgtagggatgttg
ggagcagaatctacaaagcttaacaatcaagctcgtttcatattagagaagatacaaggg
aaaattgctatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggt
tatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaa
gaatcacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccctgac
tttaattatattttaaacatgtctctgtggtctcttactaaagagaaagttgaagaactg
attaaacagagagatacaaaagggcgagaggtcaatgatcttaaaagaaaatctccttca
gatctttggaaagaagatttagcagcatttgtcgaagaactggataaagtggaagcgcaa
gaacgagaagatatgatggccggaatggctggaaaagcagtaaaaggtaaagttggcaaa
cctaaggtgaagaaacttcagctggaagagacaatgccctcaccttatgggaggagaata
gttcctgaaatcactgccatgaaggcagatgccagcaaaaagttgctgaagaagaaaaag
ggtgatcttgataccacagcagtaaaagtggaatttgatgaggaattcagtgggacaccc
gtagaaggtacaggagaggaagcactgatccagtcagttcctgtcaataaaggtccaaag
cccaaaagagagaaaaaggagcctggtaccagggtgagaaaaagaagaacacctacatca
tctggcaaacccggtgcaaagaaaatgaagaaacgtaatccttggtcagatgatgaatcc
aagtcagaaagtgacttagaagagacagagcctgtggttattccaagagattctttactt
aggagggcggctgctgagaggcctaaatacacatttgatttctcagaagaagaggatgat
gatgctgatgacaatgatgatgacaataatgatttagaggaattgaaagtcaaagcatct
cccataacaaatgatggggatgatgaatatgttccttcagatggcctagataaagatgaa
tatacattttcaccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaag
agtcaggattttgggaatctcttctcatttccttcatactctcagaagtcagaagatgat
tcagctaaatttgacagtaatgaagaagattctgcttctgttttttcaccgtcatttggt
ctgaaacaaacagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccatct
tcagatacaacccctaagcccaagagaacccccaaacagaagaagatagagactatcaac
tctgactcggattcagaatttggcattccaaagaagactacaacaccaaaaggtaaaggt
cgaggggcaaggaaaaggaaagcatctggctctgaaaatgaaggtgactataacccgggc
aggaaaacgtccaaaccaccaagcaagaaaccgaagaaaacatcttttgatcaggattca
gatgtggacatcttcccaccagacttcacttctgaaccaccttctctgccacggaccggt
cgagctaggaaagaagtaaaatattttgcagagtctgatgatgaagaagatgtcgatttt
gcaatgtttaattaa |
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