KEGG   Phyllostomus hastatus (greater spear-nosed bat): 123831214
Entry
123831214         CDS       T07912                                 
Symbol
OPTN
Name
(RefSeq) optineurin
  KO
K19946  optineurin
Organism
phas  Phyllostomus hastatus (greater spear-nosed bat)
Pathway
phas04137  Mitophagy - animal
phas04140  Autophagy - animal
phas05014  Amyotrophic lateral sclerosis
phas05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:phas00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123831214 (OPTN)
   04137 Mitophagy - animal
    123831214 (OPTN)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    123831214 (OPTN)
   05022 Pathways of neurodegeneration - multiple diseases
    123831214 (OPTN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:phas04131]
    123831214 (OPTN)
Membrane trafficking [BR:phas04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    123831214 (OPTN)
 Protein recycling
  Rab GTPases and associated proteins
   Other Rab GTPase associated proteins
    123831214 (OPTN)
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    123831214 (OPTN)
  Xenophagy
   Cargo receptors
    123831214 (OPTN)
SSDB
Motif
Pfam: CC2-LZ NEMO zf_C2H2_10 DUF8106 EDR4-like_1st Zn_ribbon_CLPX_N
Other DBs
NCBI-GeneID: 123831214
NCBI-ProteinID: XP_045713969
LinkDB
Position
Unknown
AA seq 574 aa
MSHEPLSCLTEKGDSPSETTGNGPPHLAHPNLGTFTPEELLQQMKELLIENHQLKEAMKL
NNQAMKGRFQELSAWTEKQKEERLFFETQSKEAKERLMALSHENEKLKEELGKLKRKTER
SFEDPAEDPQVPKAEAEQEMEQLKTQVVRLQAEKADLLGIVSELQLKLNSGGSSEDSFVE
IRMAEGGADVAMQEIKRSPGPTRTDATDKSRSAEGARNYLESEELTVSQLLLCLREGNQK
VERLENALKEAKKRVSDFEKKVNDRSEIETQTEGSTEKEKEEEKDRETVGSEVEALNLQV
TTLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSATPSELNEKQELIYNNKKLELQVE
SMRSEIKMEQAKREDEKSKLAILQLTHNKLLEEYSHALKTVEDLKRRESEKVDKVVLQEL
NEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTVLRAQMEVYCSDFHAERAAREKIH
EEKEQLALQLAILLKDNNVFEDGDSRQSLMEMQSRHGARTSDPDQQDYLVQRGAEDNNWR
QQQQQNIPIHSCPKCGEVLPDIDTLQIHVMDCII
NT seq 1725 nt   +upstreamnt  +downstreamnt
atgtcccacgaacctcttagctgcctgactgaaaagggggacagccccagtgaaaccact
gggaatggccccccacatctggctcacccaaacctgggcacatttaccccagaggagctg
ctgcagcaaatgaaagagctcctgattgagaaccatcagctgaaagaagccatgaagctg
aataaccaagctatgaaagggcggtttcaggagctttcagcctggacagagaaacagaag
gaggaacgccttttttttgagacccagagcaaagaagccaaagagcgcctaatggctctg
agccatgaaaatgaaaaattgaaagaagaacttggaaaactaaaacggaaaacagaaagg
tcatttgaggaccccgctgaggacccacaggtccccaaggcagaagcagaacaggaaatg
gaacagctgaagacccaagtggtccgccttcaagctgaaaaggcagatctgctgggcatt
gtgtctgaattacagctcaagctgaactcaggcggctcctctgaagactcctttgttgaa
attaggatggctgaaggaggagcagatgtggcaatgcaagaaatcaagaggagtcctggg
cccacaagaactgatgccaccgacaagagcagatctgcagaaggtgccaggaattatttg
gaatctgaggaactaactgtgagccagctcctgctttgtctaagggaaggaaaccagaag
gtggagagacttgaaaatgcactcaaggaagccaaaaaaagagtttcagattttgaaaag
aaagtcaatgatcgttctgagatcgagacccagacagaggggagcacagaaaaagagaaa
gaagaggagaaagacagagaaactgttggaagtgaggtggaagccttgaaccttcaggtg
acaaccttgtttaaggagcttcaagaggcccatacgaaactcagtgaagctgagctaatg
aagaagaggcttcaagaaaaatgtcaggcccttgaaaggaaaaattctgcaaccccatca
gagctgaatgaaaagcaagagcttatttacaataacaaaaagttagagctacaagtggaa
agcatgcgatcggaaatcaaaatggagcaggcaaaacgggaagacgaaaagtccaaatta
gccattctacagctgacacacaacaaactccttgaagaatacagtcacgcactgaaaaca
gttgaagacctaaaacggagagagtcagaaaaagtggataaggtggtgctgcaggaacta
aatgaaaaactggaactggcagagaaggcgctggcttccaagcagcttcagatggatgag
atgaagcagaccattgccaagcaggaggaggacctggaaaccatgacagttcttagggcg
cagatggaggtttactgttcagactttcatgctgaaagagcagcaagagagaagattcat
gaagaaaaggagcagcttgcattgcagctggcaattttgctgaaagacaataatgttttt
gaagatggagacagtaggcagtccttgatggaaatgcagagccgtcatggggccagaacc
agtgaccccgaccagcaggattaccttgttcaaagaggagctgaggataataactggcgg
caacagcaacagcagaatataccaattcattcttgccccaaatgtggagaagttctgccc
gacatagacacattacaaattcatgtcatggactgcatcatttaa

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