Pedobacter heparinus: Phep_0078
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Entry
Phep_0078 CDS
T00978
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
phe
Pedobacter heparinus
Pathway
phe00300
Lysine biosynthesis
phe00550
Peptidoglycan biosynthesis
phe01100
Metabolic pathways
phe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
phe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Phep_0078
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Phep_0078
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Phep_0078
Enzymes [BR:
phe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Phep_0078
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACU02304
UniProt:
C6XXQ0
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All DBs
Position
complement(81609..82910)
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AA seq
433 aa
AA seq
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MTSIGSLYQHYLNHSTVCTDTRNIVPGCLFFALKGEKFDANTFAEEALKLGAAYSIIDNE
AYQTNERCLLVSDVLTALQDLARHHRSQLHIPVVGLTGSNGKTTTKELINAVLSRKYKTF
ATRGNLNNHIGVPLSILSLGPEIEMAVIEMGANHQKEIEFLCGIAQPTHGLITNIGMAHL
DGFGGFEGVKKGKAELFAYLKQHSGFAFINRNNPYLLEMSEKAQLSKVVYYGTESSNTVA
GKLLKTDPFIELSWQSKAGEFYIALNLTGAYNFENILAAVCIGQFFEVSPVEINAGLSGY
FPNNNRSQLTKTASNTVICDFYNANPSSMAAALTNIELLKGSNKTVIIGDMFELGEESAK
QHLNIIEQAEKLDIATLIFIGKHFYHAKQNHKGHFFATPAEAAAFLKTNPLKNALILLKG
SRGMALEQLMPLL
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atgacaagcataggctccctatatcagcattacctcaaccacagcactgtatgtactgat
acaaggaatattgtacctggttgtcttttttttgcccttaaaggcgaaaaatttgatgcc
aacacctttgcagaagaggccctgaagcttggtgcagcatacagcatcatcgataatgaa
gcttatcaaaccaatgagcgttgcctgctggttagcgatgtactgaccgccctgcaggac
ctggccaggcatcaccgttcgcaactccatatccccgtggttggccttacaggtagtaat
ggcaaaaccaccacgaaggaactgatcaatgccgtgctttcccgcaaatacaaaaccttt
gccaccaggggcaatctgaataaccatatcggggttccgctttctatcctgtcccttgga
cccgaaatagaaatggctgtgatagaaatgggtgccaatcatcaaaaggagattgaattt
ctttgtggcatagcccagcctacacatggcctgatcaccaatattggcatggcccatttg
gacggatttggcggctttgaaggggtaaaaaaggggaaagcagaactgtttgcttacctg
aagcagcattcgggttttgcgttcatcaaccgcaacaacccttatttattagagatgagc
gaaaaagcgcaattgagcaaagttgtttattatggtactgaaagcagcaatacggtagct
ggaaagctcttaaaaacagatccctttattgaactttcctggcaaagcaaggccggcgaa
ttctacatcgccttaaacttaaccggtgcttataactttgaaaatatccttgctgccgta
tgtatcggccagttttttgaagtaagcccggtagagatcaatgccggcctgtcgggctat
ttccccaacaacaaccgctcacagttaaccaaaaccgccagtaacaccgtgatctgcgat
ttttacaatgccaatccaagcagtatggctgcagccttaaccaatattgaattgttaaag
ggcagcaacaaaacggtgattatcggagatatgtttgaattgggggaagaatcggccaaa
cagcacctgaacattattgaacaggcagaaaagctagatattgctacgcttatttttatt
ggaaaacacttttaccatgcgaaacaaaaccacaagggccatttttttgccaccccggca
gaggcagctgcatttttgaaaacaaacccgctaaaaaatgccctgatcttacttaaaggg
tcgcgtggaatggcattggagcaactgatgcccttgctttaa
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