Pseudonocardia sp. HH130630-07: AFB00_00740
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Entry
AFB00_00740 CDS
T04486
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
phh
Pseudonocardia sp. HH130630-07
Pathway
phh00300
Lysine biosynthesis
phh00550
Peptidoglycan biosynthesis
phh01100
Metabolic pathways
phh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
phh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AFB00_00740
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AFB00_00740
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AFB00_00740
Enzymes [BR:
phh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AFB00_00740
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ANY05093
UniProt:
A0A1B1ZH77
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Position
complement(159090..160601)
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AA seq
503 aa
AA seq
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MIEMTLAEVATVTGGRLHRVPGPPPAGAADPSGEPAEAAAATVTSVEFDSRAVGPGALFL
ALPGARADGHDFAAAAVARGATGVLAGREVDAPAVVVPPIERRDSHTYLGAVDPDGRGAA
VLAGLGRLARHVLGALPGLAVVGVTGSAGKTSTKDLLAAVLSPLGRTVAPPESFNNELGT
PWTALRADASTRHLVLEFSARGAGHIADLCAVAPPRIGVVLNVGSAHLGEFGSRAGIAAA
KGELVEALPPGDLPSYPSGPSRGGVAVLNADDELVLAMRSRTPARVVTFGRSADADVRAC
DETLVAGRATFRLVTPAGSAPVTLRLVGAHQVPNALAAAAVALELGGTPEQIARALSAAE
PASRWRMEVTDRADGVTVVNDAYNANPEAMRAALSALVSVAGPQRRTWAVLGPMGEIGAD
ADAAHAELVDVADAAGVGRVVAVGSPGYGPGAEHVDDVAAALELLRGALEPGDVVLVKAS
RAAGLERVAAGLLGSATEGLARR
NT seq
1512 nt
NT seq
+upstream
nt +downstream
nt
atgatcgagatgaccctggccgaggtggccacggtgaccggcggccggttgcaccgggtg
cccggccccccgccggccggcgccgcggacccgtccggcgagcctgctgaggccgctgcg
gcgaccgtcacgagcgtcgagttcgactcgcgggcggtcggcccgggggccctgttcctg
gcgctgccgggtgcccgggccgacggccacgacttcgccgccgccgcggtggcccgtggc
gcgaccggggtgctggccgggcgggaggtcgacgcacccgccgtcgtcgtcccgccgatc
gagcgccgggactcccacacctacctcggcgccgtcgacccggacggccggggcgccgcg
gtgctcgccgggctgggccggctggcccggcacgtgctgggcgcgctgccggggctggcc
gtggtcggggtgaccggcagcgccggcaagacctccaccaaggacctgctggccgccgtg
ctgtccccgctgggccgcacggtcgccccgccggagtcgttcaacaacgagctcgggacg
ccgtggacggcgctgcgggcggacgcgtcgacccggcacctcgtgctcgagttctccgcc
cgcggggccggccacatcgccgacctgtgcgcggtggcgccgccgcggatcggcgtcgtg
ctcaacgtcggctcggcgcacctgggtgagttcggctcccgggccgggatcgccgccgcg
aagggcgagctggtcgaggcgctgccccccggtgacttgcccagctacccgtccgggccg
tcccgcggcggggtcgccgtcctcaacgccgacgacgagctcgtcctcgccatgcgcagc
cgtaccccggcccgggtggtcacgttcgggcggtcggccgacgccgacgtccgggcgtgc
gacgagacgctggtcgcgggccgtgcgacgttccggctggtcaccccggccggatcggca
ccggtcacgctgcggctggtcggtgcgcaccaggtcccgaacgcgctcgccgcggcggcg
gtcgcgctggagctgggcgggacgccggagcagatcgcgcgggcgctgtcggccgcggag
ccggcgtcgcgctggcggatggaggtcaccgaccgggcggacggcgtcacggtcgtcaac
gacgcctacaacgccaaccccgaggccatgcgcgccgcgctgtccgcactcgtgtcggtc
gccggtccgcagcgccgcacctgggcggtgctgggcccgatgggggagatcggtgccgac
gccgacgcggcccacgccgagctggtcgacgtcgcggacgccgcgggtgtcggccgggtg
gtggccgtcggcagtcccggctacgggccgggcgccgagcacgtcgacgacgtcgcggcg
gcgctggaactcctgcgcggtgcgctcgaacccggtgacgtcgtgctcgtgaaggcctcg
cgcgcggccgggctggagcgggtcgcggccggcctgctgggctcggcgaccgaggggctg
gcccgccggtga
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