Pseudonocardia sp. HH130630-07: AFB00_21800
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Entry
AFB00_21800 CDS
T04486
Name
(GenBank) 2-oxoisovalerate dehydrogenase
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
phh
Pseudonocardia sp. HH130630-07
Pathway
phh00280
Valine, leucine and isoleucine degradation
phh00640
Propanoate metabolism
phh00785
Lipoic acid metabolism
phh01100
Metabolic pathways
phh01110
Biosynthesis of secondary metabolites
phh01210
2-Oxocarboxylic acid metabolism
Module
phh_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
phh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
AFB00_21800
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
AFB00_21800
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AFB00_21800
Enzymes [BR:
phh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
AFB00_21800
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Motif
Pfam:
Transket_pyr
Transketolase_C
PFOR_II
PDE8A_N
Motif
Other DBs
NCBI-ProteinID:
ANY08469
UniProt:
A0A1B1ZRS8
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Position
4585096..4586100
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AA seq
334 aa
AA seq
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MSTQKTTMAQAITTALRDAMTADGSVVVFGEDVAQLGGVFRVTDGLHRDFGESRCFDTPL
AESGIVGMAVGMAMNGMRPVVEMQFDAFAYPAFEQITSHVAKLANRTRGRVRLPMVIRIP
YAGGIGGVEHHCDSSEAYYAHTPGLTVLTPATNADAYGLLRAAIESPDPVVFLEPKKHYF
AKEEIDLAAPVPPIGRAMVRRAGRDATLVAYGPSVPVALAAAEQAATEQAATEGRDLGVV
DLRSIVPFDDETVCAEVRRTGRAVVIAEAPGFASVASEIAARVGERCFHHLEAPVRRVTG
FDVPYPAPKLERHYLPGVDRILDAVDDLQWEHAA
NT seq
1005 nt
NT seq
+upstream
nt +downstream
nt
atgagcacgcagaagacgacgatggcgcaggcgatcaccaccgcgttgcgcgacgcgatg
accgccgacgggtccgtggtggtgttcggcgaggacgtcgcgcagctcggcggcgtcttc
cgggtgaccgacgggttgcaccgggacttcggcgagagccgctgcttcgacaccccgctc
gccgagtccggcatcgtcggcatggcggtgggcatggcgatgaacgggatgcgcccggtc
gtcgagatgcagttcgacgcgttcgcctacccggcgttcgagcagatcaccagccacgtc
gcgaagctggcgaaccggacccgaggccgggtgcggctgccgatggtcatccggatcccg
tacgcgggcgggatcggcggggtggagcaccactgcgactcctcggaggcctactacgcg
cacacgccgggactgaccgtgctcaccccggccacgaacgccgacgcctacggcctgctg
cgcgccgcgattgagagtcccgacccggtggtgttcctggaaccgaagaagcactacttc
gcgaaggaggagatcgacctcgccgcgcccgtgccgccgatcgggcgcgcgatggtgcgc
cgggccgggcgggacgcgacgctcgtcgcgtacggcccgtcggtgccggtggcgctggcc
gccgccgagcaggccgccaccgagcaggccgccaccgaggggcgcgacctcggcgtggtg
gacctgcggtcgatcgtgccgttcgacgacgagacggtctgtgccgaggtgcgacgcacc
ggccgggcggtggtgatcgccgaggcacccgggttcgcgtcggtcgcctcggagatcgcc
gcccgggtcggggagcgctgcttccaccacctggaggcgccggtgcgccgggtgaccggg
ttcgacgttccctacccggccccgaagctcgaacggcactacctccccggcgtcgaccgc
atcctcgacgccgtcgacgacctgcagtgggagcacgcggcatga
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